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So I left up this picture.
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This is a picture of how
blood flows in a baby right
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after it's born, and
all the different parts
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of that circulation and
all the different names.
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And the reason I left
this up is because I
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want to talk about
all the changes
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that then happen
as we grow older.
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So you know, let's take
myself for example.
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I'm an adult now.
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And as an adult, what are
all of the structures called?
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Or what becomes of all
these things in my body?
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Well, for starters, if I
look down at my belly button,
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I'm not going to see
a little smiley face.
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Right?
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I'm not going to see
any blood vessels.
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I'm just going to see skin.
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And that's because all these
blood vessels have really,
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for a long time in my body,
not been delivering blood.
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So that's the first kind of
change I want to point out.
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Now, what used to be the
umbilical vein over here
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has, in my body,
become a ligament.
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All of that, from
many years ago,
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there was some clotted
blood in there.
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But over the years-- in
fact, shortly after birth,
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this started getting fibrosed.
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And lots of tissue kind
of fell into this area,
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and it became almost like
what happens with a scab.
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You get lots of
proteins in there.
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And you don't really have
a space anymore for blood
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to flow.
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So this becomes a ligament.
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In fact, there's a
ligament that extends
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towards the portal vein.
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And even the ductus
venosus, that
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becomes a ligament as well.
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So all these become ligaments.
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In fact, they have
fancy Latin names.
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So let me actually just
replace this umbilical vein
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with what it's
called in my body.
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And in my body we call it
the ligamentum teres hepatis.
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So if you want to impress
your friends, you can say, ah,
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do you mean my
ligamentum teres hepatis?
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And that's what becomes
of the umbilical vein.
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This is actually kind of
a tricky word to remember.
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But "hepatis" refers to liver.
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So you know that this is
headed towards the liver.
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So you can remember it that way.
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And over on this side,
this ductus venosus, well,
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it's no longer a
duct, right? "Duct"
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implies that you can actually
pass something through it.
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And the way I've drawn it,
it's a ligament, right?
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So it's a ligament.
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And we're actually going to
name it something fancy as well.
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We'll call it
ligamentum-- so kind
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of starting out the same
way as the other one.
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This one is ligamentum venosum.
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So remember it used
to be ductus venosus.
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So now we call this
the ligamentum venosum.
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So that's fairly
easy to remember.
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So two ligamentums
so far, right?
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And I promise you we're going
to have a few more before we're
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done.
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Now moving on, we have blood
entering the right atrium.
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And you know blood
in the fetus used
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to go from the right
atrium to the left atrium
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through the foramen ovale.
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But then we talked
about how it closes
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when the pressure
on the left side
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gets higher than the
pressure on the right side.
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And so when it closes, the
idea is that, over time, there
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is actually going to be
some-- some tissue is going
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to basically form
between those two flaps.
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And so it actually
creates a real seal.
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And when that happens, then
that space-- this space right
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here-- becomes known
as the fossa ovalis.
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So that's what it might be
called in me or you today.
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If you were to actually look
inside of the right atrium,
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you would spot a
tiny little hole
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on the wall that has
tissue on the other side,
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and that's called
the fossa ovalis.
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But it turns out
that in many adults,
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you actually don't
have a real seal there.
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So the way I've drawn it
where there's actually
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a little seal between the
two, that may not even happen.
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In fact, let's say in
about 20%, or sometimes
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you'll see the
number 25% of adults,
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you actually just
have two flaps that
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could theoretically kind of move
apart from each other again.
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And so if you're one of those
20%, let's say 20 to 25%,
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if you're one of
them, then you'd
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have what's called a
patent foramen ovale.
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And if you're part
of the majority,
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then, the other 75 to 80%,
then you'd have a fossa ovalis.
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So really all that means
is that some people have
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a real seal that connects
the two flaps of tissue,
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and some people
don't have a seal.
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And so the two
flaps can actually
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move apart from each other if
the pressure on the right side
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gets really high.
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So in a person with a patent
foramen ovale, theoretically,
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if you had a lot of pressure on
this right side, on that spot,
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you would actually
open that flap up.
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And you could actually
have a situation
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like this, where all of a
sudden now, you can actually
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move blood between the two.
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So this is actually an
interesting thought process.
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You can actually move
blood from the right side
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to the left in people
with what they call a PFO.
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But for most people, the
pressure on the right side
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really never gets that high.
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So even if you have a
PFO, because the pressure
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on the right side
is almost always
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lower than the left
side, it almost always
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means that this
flap will stay shut.
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So even with a PFO, the
vast majority of people
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never even know it.
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In fact, they go on living
their lives very happily,
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even though there's really no
seal sealing that thing off.
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Now moving onwards, we
have the ductus arteriosus.
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And so we know that this,
shortly after birth,
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is going to kind of tighten up.
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The muscles constrict when
they face all those high oxygen
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levels and they can sense
the low prostaglandins.
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And this ductus
arteriosus then, it really
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doesn't have this name anymore.
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It gets changed.
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And in an adult, I'm
going to give you
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a moment to guess
as I write it out.
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Again, ligamentum-- and
I'll give you a clue.
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Try to remember what we
called this guy over here.
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We're going to call this
one ligamentum arteriosum.
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So you're getting the hint
for how we name these things.
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And now if we follow the
blood down, down, down,
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down the aorta, it goes into
the internal iliac artery.
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That's this guy on the left
and this guy on the right.
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And the internal iliac
artery has lots of branches.
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And we haven't drawn all the
branches, but there are many.
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And eventually, it
was going to lead
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into what we used to call
the umbilical artery.
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Now, these umbilical
arteries, just
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like the ductus
arteriosus, actually
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starts kind of constricting
once the oxygen levels go up
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and once the prostaglandins
levels go down.
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And when it constricts,
it turns into a ligament.
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And this is also
because there's no blood
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flow through this area.
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And the last place where
there is blood flow
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is going to maintain blood flow.
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So there were branches, I said.
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And of course, through
these branches,
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blood is flowing to
other areas, right?
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Blood it's going to, let's say,
different structures inside
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of our pelvis.
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And these last couple
of branches right here,
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these are headed
towards our bladder.
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So sometimes you'll see that.
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You'll see that
they'll say part of it
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turns into an artery
towards the bladder.
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And the other part
turns into a ligament.
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So let's actually erase this
word, "umbilical artery,"
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and replace it with
the correct word, which
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is that it turns
into the medial--
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and actually, this is very
important, because people get
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confused on this
point all the time.
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I'm going to point to the L--
medial umbilical ligament.
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And there are two of
them, of course, right?
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Because there are two arteries.
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So I should write medial
umbilical ligaments,
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two of them.
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So then just to
kind of summarize,
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we have a few ligaments down
here by our belly button.
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We have one important
ligament that's in our liver.
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We also have one up by
our aorta separating it
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from the pulmonary artery.
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And finally, we have-- either
you have a sealed-off version,
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and we call that a fossa
ovalis in our heart,
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or you have a patent
foramen ovale.
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And even if that's the
case, for most of us,
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that is not a problem.