Saffron is the most expensive spice in the world. Its cultivation and harvesting are very laborious and about 250,000 flowers are needed to obtain one kilogram of pure saffron. A very high-quality saffron is grown in Kashmir, which is also a key ingredient in the traditional cuisine of the region, as well as in the rest of India, where it is used as a condiment, medicine or dye. However, the current political instability in the Kashmir region, the confinement due to the COVID-19 pandemic and the effects of global warming are impacting negatively the cultivation of saffron in this region and threatens the future of the production of this spice for the thousands of families that have depended on it for generations.