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To detect diseases earlier, let's speak bacteria's secret language

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    You don't know them.
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    You don't see them.
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    But they're always around,
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    whispering,
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    making secret plans,
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    building armies with millions of soldiers.
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    And when they decide to attack,
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    they all attack at the same time.
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    I'm talking about bacteria.
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    (Laughter)
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    Who did you think I was talking about?
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    Bacteria live in communities
    just like humans.
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    They have families,
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    they talk
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    and they plan their activities.
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    And just like humans,
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    they trick, deceive and some might
    even cheat on each other.
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    What if I tell you that we can listen
    to bacterial conversations
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    and translate their confidential
    information into human language?
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    And what if I tell you that translating
    bacterial conversations can save lives?
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    I hold a PhD in nanophysics,
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    and I've used nanotechnology
    to develop a real-time translation tool
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    that can spy on bacterial communities
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    and give us recordings of what
    bacteria are up to.
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    Bacteria live everywhere:
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    they're in the soil,
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    on our furniture
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    and inside our bodies.
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    In fact 90 percent of all of life's cells
    in this theatre are bacterial.
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    Some bacteria are good for us:
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    they help us digest food
    or produce antibiotics.
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    And some bacteria are bad for us:
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    they cause diseases and death.
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    To coordinate all the functions
    bacteria have,
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    they have to be able to organize,
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    and they do that just like us humans --
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    by communicaiting.
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    But instead of using words,
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    they use signaling
    molecules with each other.
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    When bacteria are few,
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    the signaling molecules just flow away.
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    Like the screams of a man
    alone in the desert.
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    But when their are many bacteria,
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    the signaling molecules accumulate,
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    and the bacteria start sensing
    that they're not alone.
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    They listen to each other.
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    In this way, they keep track
    of how many they are
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    and when they're many enough
    to iniate a new action.
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    And when the signaling molecules
    have reached a certain threshold,
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    all the bacteria sense at once
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    that they need to act
    with the same action.
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    So bacterial conversation consists
    of an initiative and a reaction.
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    A production of a molecule
    and the response to it.
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    In my research I focused on spying
    on bacterial communities
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    inside the human body.
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    How does it work?
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    We have a sample from a patient.
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    It could be a blood or spit sample.
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    We shoot electrons into the sample,
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    the electrons will interact with any
    communication molecules present,
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    and this interaction
    will give us information
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    on the identity of the bacteria,
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    the type of communication
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    and how much the bacteria are talking.
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    But what is it like
    when bacteria communicate?
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    Before I developed the translation tool,
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    my first assumption
Title:
To detect diseases earlier, let's speak bacteria's secret language
Speaker:
Fatima AlZahra'a Alatraktchi
Description:

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Video Language:
English
Team:
closed TED
Project:
TEDTalks
Duration:
11:41

English subtitles

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