1 00:00:07,123 --> 00:00:09,763 When a team of archaeologists recently came across 2 00:00:09,763 --> 00:00:13,003 some 15,000 year-old human remains, 3 00:00:13,003 --> 00:00:15,293 they made an interesting discovery. 4 00:00:15,293 --> 00:00:19,122 The teeth of those ancient humans were riddled with holes. 5 00:00:19,122 --> 00:00:23,942 Their cavities were caused by the same thing that still plagues us today, 6 00:00:23,942 --> 00:00:28,124 specific tiny microbes that live in our mouths. 7 00:00:28,124 --> 00:00:30,512 These microbes are with us soon after birth. 8 00:00:30,512 --> 00:00:34,313 We typically pick them up as babies from our mothers' mouths. 9 00:00:34,313 --> 00:00:35,924 And as our teeth erupt, 10 00:00:35,924 --> 00:00:39,943 they naturally begin to accumulate communities of bacteria. 11 00:00:39,943 --> 00:00:41,194 Depending on what we eat, 12 00:00:41,194 --> 00:00:43,621 and specifically how much sugar we consume, 13 00:00:43,621 --> 00:00:48,493 certain microbes can overpopulate and cause cavities. 14 00:00:48,493 --> 00:00:52,343 Diets high in sugary foods cause an explosion of bacteria 15 00:00:52,343 --> 00:00:55,994 called mutans streptococci in our mouths. 16 00:00:55,994 --> 00:00:58,874 Like humans, these microorganisms love sugar, 17 00:00:58,874 --> 00:01:03,306 using it as a molecular building block and energy source. 18 00:01:03,306 --> 00:01:04,653 As they consume it, 19 00:01:04,653 --> 00:01:07,944 the bacteria generate byproducts in the form of acids, 20 00:01:07,944 --> 00:01:09,894 such as lactic acid. 21 00:01:09,894 --> 00:01:13,144 Mutans streptococci are resistant to this acid, 22 00:01:13,144 --> 00:01:16,314 but unfortunately, our teeth aren't. 23 00:01:16,314 --> 00:01:20,404 While each human tooth is coated in a hardy, protective layer of enamel, 24 00:01:20,404 --> 00:01:22,803 it's no match for acid. 25 00:01:22,803 --> 00:01:28,154 That degrades the armor over time, leaching away its calcium minerals. 26 00:01:28,154 --> 00:01:31,575 Gradually, acid wears down a pathway for bacteria 27 00:01:31,575 --> 00:01:35,576 into the tooth's secondary layer called the dentin. 28 00:01:35,576 --> 00:01:40,195 Since blood vessels and nerves in our teeth are enclosed deep within, 29 00:01:40,195 --> 00:01:43,875 at this stage, the expanding cavity doesn't hurt. 30 00:01:43,875 --> 00:01:46,045 But if the damage extends beyond the dentin, 31 00:01:46,045 --> 00:01:48,376 the bacterial invasion progresses 32 00:01:48,376 --> 00:01:52,856 causing excruciating pain as the nerves become exposed. 33 00:01:52,856 --> 00:01:55,665 Without treatment, the whole tooth may become infected 34 00:01:55,665 --> 00:01:57,346 and require removal 35 00:01:57,346 --> 00:02:00,586 all due to those sugar-loving bacteria. 36 00:02:00,586 --> 00:02:02,505 The more sugar our food contains, 37 00:02:02,505 --> 00:02:04,895 the more our teeth are put at risk. 38 00:02:04,895 --> 00:02:09,826 Those cavemen would hardly have indulged in sugary treats, however, 39 00:02:09,826 --> 00:02:11,977 so what caused their cavities? 40 00:02:11,977 --> 00:02:16,135 In meat-heavy diets, there would have been a low-risk of cavities developing 41 00:02:16,135 --> 00:02:19,256 because lean meat contains very little sugar, 42 00:02:19,256 --> 00:02:22,285 but that's not all our early human ancestors ate. 43 00:02:22,285 --> 00:02:27,285 Cavemen would also have consumed root vegetables, nuts, and grains, 44 00:02:27,285 --> 00:02:29,830 all of which contain carbohydrates. 45 00:02:29,830 --> 00:02:32,027 When exposed to enzymes in the saliva, 46 00:02:32,027 --> 00:02:35,645 carbohydrates get broken down into simpler sugars, 47 00:02:35,645 --> 00:02:40,105 which can become the fodder for those ravenous mouth bacteria. 48 00:02:40,105 --> 00:02:44,376 So while ancient humans did eat less sugar compared to us, 49 00:02:44,376 --> 00:02:47,392 their teeth were still exposed to sugars. 50 00:02:47,392 --> 00:02:50,666 That doesn't mean they were unable to treat their cavities, though. 51 00:02:50,666 --> 00:02:54,638 Archaeological remains show that about 14,000 years ago, 52 00:02:54,638 --> 00:03:00,549 humans were already using sharpened flint to remove bits of rotten teeth. 53 00:03:00,549 --> 00:03:02,917 Ancient humans even made rudimentary drills 54 00:03:02,917 --> 00:03:06,018 to smooth out the rough holes left behind 55 00:03:06,018 --> 00:03:10,369 and beeswax to plug cavities, like modern-day fillings. 56 00:03:10,369 --> 00:03:13,387 Today, we have much more sophisticated techniques and tools, 57 00:03:13,387 --> 00:03:17,877 which is fortunate because we also need to contend with our more damaging, 58 00:03:17,877 --> 00:03:20,180 sugar-guzzling ways. 59 00:03:20,180 --> 00:03:24,559 After the Industrial Revolution, the human incidence of cavities surged 60 00:03:24,559 --> 00:03:27,308 because suddenly we had technological advances 61 00:03:27,308 --> 00:03:31,209 that made refined sugar cheaper and accessible. 62 00:03:31,209 --> 00:03:37,058 Today, an incredible 92% of American adults have had cavities in their teeth. 63 00:03:37,058 --> 00:03:39,947 Some people are more susceptible to cavities due to genes 64 00:03:39,947 --> 00:03:42,998 that may cause certain weaknesses, like softer enamel, 65 00:03:42,998 --> 00:03:46,928 but for most, high sugar consumption is to blame. 66 00:03:46,928 --> 00:03:50,218 However, we have developed other ways of minimizing cavities 67 00:03:50,218 --> 00:03:53,750 besides reducing our intake of sugar and starch. 68 00:03:53,750 --> 00:03:56,630 In most toothpastes and many water supplies, 69 00:03:56,630 --> 00:03:59,328 we use tiny amounts of fluoride. 70 00:03:59,328 --> 00:04:03,109 That strengthens teeth and encourages the growth of enamel crystals 71 00:04:03,109 --> 00:04:06,470 that build up a tooth's defenses against acid. 72 00:04:06,470 --> 00:04:08,020 When cavities do develop, 73 00:04:08,020 --> 00:04:11,909 we use tooth fillings to fill and close off the infected area, 74 00:04:11,909 --> 00:04:13,989 preventing them from getting worse. 75 00:04:13,989 --> 00:04:18,120 The best way to avoid a cavity is still cutting down on sugar intake 76 00:04:18,120 --> 00:04:20,151 and practicing good oral hygiene 77 00:04:20,151 --> 00:04:23,051 to get rid of the bacteria and their food sources. 78 00:04:23,051 --> 00:04:24,900 That includes regular tooth brushing, 79 00:04:24,900 --> 00:04:25,909 flossing, 80 00:04:25,909 --> 00:04:27,160 and avoiding sugary, 81 00:04:27,160 --> 00:04:28,003 starchy, 82 00:04:28,003 --> 00:04:31,671 and sticky foods that cling to your teeth between meals. 83 00:04:31,671 --> 00:04:36,050 Gradually, the population of sugar-loving microbes in your mouth will decline. 84 00:04:36,050 --> 00:04:38,102 Unlike the cavemen of yesteryear, 85 00:04:38,102 --> 00:04:41,950 today we have the knowledge required to avert a cavity calamity. 86 00:04:41,950 --> 00:04:43,700 We just need to use it.