WEBVTT 00:00:14.004 --> 00:00:16.183 One of the great things about science 00:00:16.207 --> 00:00:18.745 is that when scientists make a discovery, 00:00:18.769 --> 00:00:21.275 it's not always in a prescribed manner, 00:00:21.299 --> 00:00:24.419 as in, only in a laboratory under strict settings, 00:00:24.443 --> 00:00:25.864 with white lab coats 00:00:25.888 --> 00:00:29.108 and all sorts of neat science gizmos that go, "Beep!" 00:00:29.715 --> 00:00:31.033 In reality, 00:00:31.057 --> 00:00:32.486 the events and people involved 00:00:32.510 --> 00:00:34.879 in some of the major scientific discoveries 00:00:34.903 --> 00:00:37.292 are as weird and varied as they get. 00:00:37.645 --> 00:00:39.226 My case in point: 00:00:39.250 --> 00:00:41.929 The Weird History of the Cell Theory. 00:00:42.633 --> 00:00:44.762 There are three parts to the cell theory. 00:00:44.786 --> 00:00:48.909 One: all organisms are composed of one or more cells. 00:00:48.933 --> 00:00:51.449 Two: the cell is the basic unit of structure 00:00:51.473 --> 00:00:53.337 and organization in organisms. 00:00:53.361 --> 00:00:57.484 And three: all cells come from preexisting cells. 00:00:57.508 --> 00:01:01.548 To be honest, this all sounds incredibly boring 00:01:01.572 --> 00:01:03.307 until you dig a little deeper 00:01:03.331 --> 00:01:05.976 into how the world of microscopic organisms, 00:01:06.000 --> 00:01:08.014 and this theory came to be. 00:01:08.038 --> 00:01:11.049 It all started in the early 1600s in the Netherlands, 00:01:11.073 --> 00:01:13.736 where a spectacle maker named Zacharias Janssen 00:01:13.760 --> 00:01:17.260 is said to have come up with the first compound microscope, 00:01:17.284 --> 00:01:19.034 along with the first telescope. 00:01:19.058 --> 00:01:20.871 Both claims are often disputed, 00:01:20.895 --> 00:01:23.285 as apparently he wasn't the only bored guy 00:01:23.309 --> 00:01:26.290 with a ton of glass lenses to play with at the time. 00:01:26.314 --> 00:01:27.465 Despite this, 00:01:27.489 --> 00:01:29.852 the microscope soon became a hot item 00:01:29.876 --> 00:01:33.304 that every naturalist or scientist at the time wanted to play with, 00:01:33.328 --> 00:01:36.195 making it much like the iPad of its day. 00:01:36.219 --> 00:01:37.752 One such person 00:01:37.776 --> 00:01:41.280 was a fellow Dutchman by the name of Anton van Leeuwenhoek, 00:01:41.304 --> 00:01:43.566 who heard about these microscope doohickeys, 00:01:43.590 --> 00:01:45.874 and instead of going out and buying one, 00:01:45.898 --> 00:01:47.729 he decided to make his own. 00:01:47.753 --> 00:01:50.494 And it was a strange little contraption indeed, 00:01:50.518 --> 00:01:54.485 as it looked more like a tiny paddle the size of a sunglass lens. 00:01:54.509 --> 00:01:56.044 If he had stuck two together, 00:01:56.068 --> 00:01:58.847 it probably would have made a wicked set of sunglasses 00:01:58.871 --> 00:02:01.844 that you couldn't see much out of. 00:02:01.868 --> 00:02:04.756 Anyhoo, once Leeuwenhoek had his microscope ready, 00:02:04.780 --> 00:02:05.935 he went to town, 00:02:05.959 --> 00:02:08.493 looking at anything and everything he could with them, 00:02:08.517 --> 00:02:10.378 including the gunk on his teeth. 00:02:10.775 --> 00:02:13.028 Yes, you heard right. 00:02:13.052 --> 00:02:15.100 He actually discovered bacteria 00:02:15.124 --> 00:02:17.577 by looking at dental scrapings, 00:02:17.601 --> 00:02:19.267 which, when you keep in mind 00:02:19.291 --> 00:02:23.644 that people didn't brush their teeth much -- if at all -- back then, 00:02:23.668 --> 00:02:27.185 he must have had a lovely bunch of bacteria to look at. 00:02:27.594 --> 00:02:29.285 When he wrote about his discovery, 00:02:29.309 --> 00:02:32.061 he didn't call them bacteria, as we know them today. 00:02:32.085 --> 00:02:34.246 But he called them "animalcules," 00:02:34.270 --> 00:02:36.857 because they looked like little animals to him. 00:02:36.881 --> 00:02:39.200 While Leeuwenhoek was staring at his teeth gunk, 00:02:39.224 --> 00:02:42.320 he was also sending letters to a scientific colleague in England, 00:02:42.344 --> 00:02:44.244 by the name of Robert Hooke. 00:02:44.268 --> 00:02:48.774 Hooke was a guy who really loved all aspects of science, 00:02:48.798 --> 00:02:51.838 so he dabbled in a little bit of everything, including physics, 00:02:51.862 --> 00:02:53.365 chemistry and biology. 00:02:53.776 --> 00:02:57.440 Thus it is Hooke who we can thank for the term "the cell," 00:02:57.464 --> 00:03:00.675 as he was looking at a piece of cork under his microscope, 00:03:00.699 --> 00:03:04.973 and the little chambers he saw reminded him of cells, 00:03:04.997 --> 00:03:08.682 or the rooms monks slept in in their monasteries. 00:03:09.158 --> 00:03:10.698 Think college dorm rooms, 00:03:10.722 --> 00:03:14.359 but without the TVs, computers and really annoying roommates. 00:03:14.836 --> 00:03:17.349 Hooke was something of an underappreciated scientist 00:03:17.373 --> 00:03:18.524 of his day -- 00:03:18.548 --> 00:03:20.187 something he brought upon himself, 00:03:20.211 --> 00:03:22.085 as he made the mistake of locking horns 00:03:22.109 --> 00:03:25.032 with one of the most famous scientists ever, Sir Isaac Newton. 00:03:25.056 --> 00:03:27.887 Remember when I said Hooke dabbled in many different fields? 00:03:27.911 --> 00:03:30.293 Well, after Newton published a groundbreaking book 00:03:30.317 --> 00:03:32.668 on how planets move due to gravity, 00:03:32.692 --> 00:03:33.844 Hooke made the claim 00:03:33.868 --> 00:03:37.542 that Newton had been inspired by Hooke's work in physics. 00:03:37.889 --> 00:03:41.275 Newton, to say the least, did not like that, 00:03:41.299 --> 00:03:43.634 which sparked a tense relationship between the two 00:03:43.658 --> 00:03:45.961 that lasted even after Hooke died, 00:03:45.985 --> 00:03:49.978 as quite a bit of Hooke's research -- as well as his only portrait -- 00:03:50.002 --> 00:03:52.674 was ... misplaced, due to Newton. 00:03:52.698 --> 00:03:56.027 Much of it was rediscovered, thankfully, after Newton's time, 00:03:56.051 --> 00:03:57.313 but not his portrait, 00:03:57.337 --> 00:04:00.123 as, sadly, no one knows what Robert Hooke looked like. 00:04:00.776 --> 00:04:02.553 Fast-forward to the 1800s, 00:04:02.577 --> 00:04:05.088 where two German scientists discovered something 00:04:05.112 --> 00:04:07.776 that today we might find rather obvious, 00:04:07.800 --> 00:04:11.243 but helped tie together what we now know as the cell theory. 00:04:11.267 --> 00:04:13.819 The first scientist was Matthias Schleiden, 00:04:13.843 --> 00:04:16.775 a botanist who liked to study plants under a microscope. 00:04:17.299 --> 00:04:19.912 From his years of studying different plant species, 00:04:19.936 --> 00:04:21.245 it finally dawned on him 00:04:21.269 --> 00:04:23.740 that every single plant he had looked at 00:04:23.764 --> 00:04:26.462 were all made of cells. 00:04:26.866 --> 00:04:28.051 At the same time, 00:04:28.075 --> 00:04:30.841 on the other end of Germany was Theodor Schwann, 00:04:30.865 --> 00:04:33.835 a scientist who not only studied slides of animal cells 00:04:33.859 --> 00:04:35.077 under the microscope 00:04:35.101 --> 00:04:38.230 and got a special type of nerve cell named after him, 00:04:38.254 --> 00:04:40.947 but also invented rebreathers for firefighters, 00:04:40.971 --> 00:04:43.282 and had a kickin' pair of sideburns. 00:04:43.306 --> 00:04:45.321 After studying animal cells for a while, 00:04:45.345 --> 00:04:47.232 he, too, came to the conclusion 00:04:47.256 --> 00:04:49.423 that all animals were made of cells. 00:04:49.447 --> 00:04:52.276 Immediately, he reached out via snail mail, 00:04:52.300 --> 00:04:54.486 as Twitter had yet to be invented, 00:04:54.510 --> 00:04:57.655 to other scientists working in the same field with Schleiden, 00:04:57.679 --> 00:04:58.840 who got back to him, 00:04:58.864 --> 00:05:01.928 and the two started working on the beginnings of the cell theory. 00:05:01.952 --> 00:05:03.885 A bone of contention arose between them. 00:05:03.909 --> 00:05:06.048 As for the last part of the cell theory -- 00:05:06.072 --> 00:05:08.680 that cells come from preexisting cells -- 00:05:08.704 --> 00:05:11.133 Schleiden didn't exactly subscribe to that thought, 00:05:11.157 --> 00:05:14.726 as he swore cells came from free-cell formation, 00:05:14.750 --> 00:05:18.611 where they just kind of spontaneously crystallized into existence. 00:05:19.009 --> 00:05:21.937 That's when another scientist named Rudolph Virchow, 00:05:21.961 --> 00:05:25.570 stepped in with research showing that cells did come from other cells, 00:05:25.594 --> 00:05:28.239 research that was actually -- hmm ... How to put it? -- 00:05:28.263 --> 00:05:30.030 "borrowed without permission" 00:05:30.054 --> 00:05:33.131 from a Jewish scientist by the name of Robert Remak, 00:05:33.155 --> 00:05:36.038 which led to two more feuding scientists. 00:05:36.062 --> 00:05:39.195 Thus, from teeth gunk to torquing off Newton, 00:05:39.219 --> 00:05:41.593 crystallization to Schwann cells, 00:05:41.617 --> 00:05:44.921 the cell theory came to be an important part of biology today. 00:05:45.301 --> 00:05:49.515 Some things we know about science today may seem boring, 00:05:49.539 --> 00:05:53.198 but how we came to know them is incredibly fascinating. 00:05:53.222 --> 00:05:54.976 So if something bores you, 00:05:55.000 --> 00:05:56.462 dig deeper. 00:05:56.486 --> 00:06:00.291 It's probably got a really weird story behind it somewhere.