1 00:00:00,000 --> 00:00:13,000 (Music) 2 00:00:13,000 --> 00:00:16,000 One of the great things about science 3 00:00:16,000 --> 00:00:18,000 is that when scientists make a discovery, 4 00:00:18,000 --> 00:00:20,000 it's not always in a prescribed manner, 5 00:00:20,000 --> 00:00:24,000 as in, only in a laboratory under strict settings, 6 00:00:24,000 --> 00:00:28,000 with white lab coats and all sorts of neat science gizmos 7 00:00:28,000 --> 00:00:29,000 that go, "Beep!" 8 00:00:29,000 --> 00:00:30,000 In reality, 9 00:00:30,000 --> 00:00:34,000 the events and people involved in some of the major scientific discoveries 10 00:00:34,000 --> 00:00:37,000 are as weird and varied as they get. 11 00:00:37,000 --> 00:00:38,000 My case in point: 12 00:00:38,000 --> 00:00:41,000 The Weird History of the Cell Theory. 13 00:00:41,000 --> 00:00:44,000 There are three parts to the cell theory. 14 00:00:44,000 --> 00:00:48,000 One: All organisms are composed of one or more cells. 15 00:00:48,000 --> 00:00:53,000 Two: The cell is the basic unit of structure and organization in organisms. 16 00:00:53,000 --> 00:00:57,000 And three: All cells come from preexisting cells. 17 00:00:57,000 --> 00:01:01,000 To be honest, this all sounds incredibly boring 18 00:01:01,000 --> 00:01:06,000 until you dig a little deeper into how the world of microscopic organisms 19 00:01:06,000 --> 00:01:07,000 and this theory came to be. 20 00:01:07,000 --> 00:01:10,000 It all started in the early 1600s, 21 00:01:10,000 --> 00:01:12,000 in the Netherlands, where a spectacle maker 22 00:01:12,000 --> 00:01:16,000 name Zacharias Jansen is said to have come up with the first compound microscope, 23 00:01:16,000 --> 00:01:18,000 along with the first telescope. 24 00:01:18,000 --> 00:01:20,000 Both claims are often disputed, 25 00:01:20,000 --> 00:01:25,000 as apparently he wasn't the only bored guy with a ton of glass lenses to play with at the time. 26 00:01:25,000 --> 00:01:27,000 Despite this, 27 00:01:27,000 --> 00:01:29,000 the microscope soon became a hot item 28 00:01:29,000 --> 00:01:33,000 that every naturalist or scientist at the time wanted to play with, 29 00:01:33,000 --> 00:01:35,000 making it much like the iPad of its day. 30 00:01:35,000 --> 00:01:37,000 One such person 31 00:01:37,000 --> 00:01:41,000 was a fellow Dutchman by the name of Anton van Leeuwenhoek, 32 00:01:41,000 --> 00:01:43,000 who heard about these microscope doohickies, 33 00:01:43,000 --> 00:01:45,000 and instead of going out and buying one, 34 00:01:45,000 --> 00:01:47,000 he decided to make his own. 35 00:01:47,000 --> 00:01:50,000 And it was a strange little contraption indeed, 36 00:01:50,000 --> 00:01:54,000 as it looked more like a tiny paddle the size of a sunglass lens. 37 00:01:54,000 --> 00:01:58,000 If he had stuck two together, it probably would have made a wicked set of sunglasses ... 38 00:01:58,000 --> 00:02:01,000 that you couldn't see much out of. 39 00:02:01,000 --> 00:02:04,000 Any-who, once Leeuwenhoek had his microscope ready, 40 00:02:04,000 --> 00:02:08,000 he went to town, looking at anything and everything he could with them, 41 00:02:08,000 --> 00:02:10,000 including the gunk on his teeth. 42 00:02:10,000 --> 00:02:12,000 Yes, you heard right. 43 00:02:12,000 --> 00:02:17,000 He actually discovered bacteria by looking at dental scrapings, 44 00:02:17,000 --> 00:02:21,000 which, when you keep in mind that people didn't brush their teeth much, 45 00:02:21,000 --> 00:02:23,000 if at all, back then, 46 00:02:23,000 --> 00:02:27,000 he must have had a lovely bunch of bacteria to look at. 47 00:02:27,000 --> 00:02:29,000 When he wrote about his discovery, 48 00:02:29,000 --> 00:02:31,000 he didn't call them bacteria, as we know them today. 49 00:02:31,000 --> 00:02:34,000 But he called them animalcules, 50 00:02:34,000 --> 00:02:36,000 because they looked like little animals to him. 51 00:02:36,000 --> 00:02:39,000 While Leeuwenhoek was staring at his teeth gunk, 52 00:02:39,000 --> 00:02:42,000 he was also sending letters to a scientific colleague in England, 53 00:02:42,000 --> 00:02:44,000 by the name of Robert Hooke. 54 00:02:44,000 --> 00:02:48,000 Hooke was a guy who really loved all aspects of science, 55 00:02:48,000 --> 00:02:53,000 so he dabbled in a little bit of everything, including physics, chemistry and biology. 56 00:02:53,000 --> 00:02:57,000 Thus it is Hooke who we can thank for the term "the cell," 57 00:02:57,000 --> 00:03:00,000 as he was looking at a piece of cork under his microscope, 58 00:03:00,000 --> 00:03:04,000 and the little chambers he saw reminded him of cells, 59 00:03:04,000 --> 00:03:08,000 or the rooms monks slept in in their monasteries. 60 00:03:08,000 --> 00:03:14,000 Think college dorm rooms, but without the TV's, computers and really annoying roommates. 61 00:03:14,000 --> 00:03:17,000 Hooke was something of an under-appreciated scientist of his day, 62 00:03:17,000 --> 00:03:19,000 something he brought upon himself, 63 00:03:19,000 --> 00:03:23,000 as he made the mistake of locking horns with one of the most famous scientists ever, 64 00:03:23,000 --> 00:03:24,000 Sir Isaac Newton. 65 00:03:24,000 --> 00:03:27,000 Remember when I said Hooke dabbled in many different fields? 66 00:03:27,000 --> 00:03:30,000 Well, after Newton published a groundbreaking book 67 00:03:30,000 --> 00:03:32,000 on how planets move due to gravity, 68 00:03:32,000 --> 00:03:34,000 Hooke made the claim that Newton 69 00:03:34,000 --> 00:03:37,000 had been inspired by Hooke's work in physics. 70 00:03:37,000 --> 00:03:40,000 Newton, to say the least, did not like that, 71 00:03:40,000 --> 00:03:45,000 which sparked a tense relationship between the two that lasted even after Hooke died, 72 00:03:45,000 --> 00:03:47,000 as quite a bit of Hooke's research, 73 00:03:47,000 --> 00:03:52,000 as well as his only portrait, was "misplaced," due to Newton. 74 00:03:52,000 --> 00:03:55,000 Much of it was rediscovered, thankfully, after Newton's time, 75 00:03:55,000 --> 00:04:00,000 but not his portrait, as sadly no one knows what Robert Hooke looked like. 76 00:04:00,000 --> 00:04:02,000 Fast-forward to the 1800s, 77 00:04:02,000 --> 00:04:07,000 where two German scientists discovered something that today we might find rather obvious, 78 00:04:07,000 --> 00:04:10,000 but helped tie together what we now know as the cell theory. 79 00:04:10,000 --> 00:04:13,000 The first scientist was Matthias Schleiden, 80 00:04:13,000 --> 00:04:16,000 a botanist who liked to study plants under a microscope. 81 00:04:16,000 --> 00:04:20,000 From his years of studying different plant species, 82 00:04:20,000 --> 00:04:23,000 it finally dawned on him that every single plant he had looked at 83 00:04:23,000 --> 00:04:26,000 were all made of cells. 84 00:04:26,000 --> 00:04:29,000 At the same time, on the other end of Germany, 85 00:04:29,000 --> 00:04:30,000 was Theodor Schwann, 86 00:04:30,000 --> 00:04:34,000 a scientist who not only studied slides of animal cells under the microscope, 87 00:04:34,000 --> 00:04:37,000 and got a special type of nerve cell named after him, 88 00:04:37,000 --> 00:04:41,000 but also invented rebreathers for firefighters 89 00:04:41,000 --> 00:04:42,000 and had a kickin' pair of sideburns. 90 00:04:42,000 --> 00:04:45,000 After studying animal cells for a while, 91 00:04:45,000 --> 00:04:49,000 he too came to the conclusion that all animals were made of cells. 92 00:04:49,000 --> 00:04:51,000 Immediately, he reached out via snail mail, 93 00:04:51,000 --> 00:04:54,000 as Twitter had yet to be invented, 94 00:04:54,000 --> 00:04:56,000 to other scientists working in the same field, 95 00:04:56,000 --> 00:05:01,000 met with Schleiden, who got back to him, and the two started working on the beginnings of the cell theory. 96 00:05:01,000 --> 00:05:03,000 A bone of contention arose between them 97 00:05:03,000 --> 00:05:05,000 as for the last part of the cell theory, 98 00:05:05,000 --> 00:05:08,000 that cells come from preexisting cells. 99 00:05:08,000 --> 00:05:11,000 Schleiden didn't exactly subscribe to that thought, 100 00:05:11,000 --> 00:05:14,000 as he swore cells came from free cell formation, 101 00:05:14,000 --> 00:05:18,000 where they just kind of spontaneously crystalized into existence. 102 00:05:18,000 --> 00:05:21,000 That's when another scientist, named Rudolph Virchow, 103 00:05:21,000 --> 00:05:25,000 stepped in with research showing that cells did come from other cells, 104 00:05:25,000 --> 00:05:29,000 research that was actually -- hmm, how to put it? -- borrowed without permission 105 00:05:29,000 --> 00:05:32,000 from a Jewish scientist by the name of Robert Remak, 106 00:05:32,000 --> 00:05:35,000 which led to two more feuding scientists. 107 00:05:35,000 --> 00:05:38,000 Thus, from teeth gunk to torquing off Newton, 108 00:05:38,000 --> 00:05:41,000 crystallization to Schwann cells, 109 00:05:41,000 --> 00:05:44,000 the cell theory came to be an important part of biology today. 110 00:05:44,000 --> 00:05:48,000 Some things we know about science today may seem boring, 111 00:05:48,000 --> 00:05:52,000 but how we came to know them is incredibly fascinating. 112 00:05:52,000 --> 00:05:55,000 So if something bores you, 113 00:05:55,000 --> 00:05:56,000 dig deeper. 114 00:05:56,000 --> 00:06:00,000 It's probably got a really weird story behind it somewhere.