9:59:59.000,9:59:59.000 This is Pleurobot. 9:59:59.000,9:59:59.000 Pleurobot is a robot that we designed[br]to closely mimic a salamander species 9:59:59.000,9:59:59.000 called ?? 9:59:59.000,9:59:59.000 Pleurobot can walk, as you can see here, 9:59:59.000,9:59:59.000 and as you'll see later, it can also swim. 9:59:59.000,9:59:59.000 So you might ask,[br]why did we design this robot? 9:59:59.000,9:59:59.000 And in fact, this robot has been designed[br]as a scientific tool for neuroscience. 9:59:59.000,9:59:59.000 Indeed, we designed it[br]together with neurobiologists 9:59:59.000,9:59:59.000 to understand how animals move, 9:59:59.000,9:59:59.000 and especially how the spinal cord[br]controls locomotion. 9:59:59.000,9:59:59.000 But the more I work in biorobotics, 9:59:59.000,9:59:59.000 the more I'm really impressed[br]by animal locomotion. 9:59:59.000,9:59:59.000 If you think of a dolphin swimming[br]or a cat running or jumping around, 9:59:59.000,9:59:59.000 or even us as humans, 9:59:59.000,9:59:59.000 when you go jogging or play tennis, 9:59:59.000,9:59:59.000 we do amazing things. 9:59:59.000,9:59:59.000 And in fact, our nervous system solves[br]a very, very complex control problem. 9:59:59.000,9:59:59.000 It has to coordinate more[br]or less 200 muscles perfectly, 9:59:59.000,9:59:59.000 because if the coordination is bad,[br]we fall over or we do bad locomotion. 9:59:59.000,9:59:59.000 And my goal is to understand[br]how this works. 9:59:59.000,9:59:59.000 There are four main components[br]behind animal locomotion. 9:59:59.000,9:59:59.000 The first component is just the body, 9:59:59.000,9:59:59.000 and in fact we should never underestimate[br]what extent the biomechanics 9:59:59.000,9:59:59.000 already simplify locomotion in animals. 9:59:59.000,9:59:59.000 Then you have the spinal cord, 9:59:59.000,9:59:59.000 and in the spinal cord you find reflexes, 9:59:59.000,9:59:59.000 like multiple reflexes that create[br]a sensory motor coordination loop 9:59:59.000,9:59:59.000 between neural activity in the spinal cord[br]and mechanical activity. 9:59:59.000,9:59:59.000 A third component[br]are central pattern generators. 9:59:59.000,9:59:59.000 These are very interesting circuits[br]in the spinal cord of vertebrate animals 9:59:59.000,9:59:59.000 that can generate, by themselves, very[br]coordinated rhythmic patterns of activity 9:59:59.000,9:59:59.000 while receiving only[br]very simple input signals. 9:59:59.000,9:59:59.000 And these input signals come from[br]descending modulation 9:59:59.000,9:59:59.000 from higher parts of the brain,[br]from the motor cortex, the cerebellum, 9:59:59.000,9:59:59.000 the basal ganglia, will all modulate[br]activity of the spinal cord 9:59:59.000,9:59:59.000 while we do locomotion. 9:59:59.000,9:59:59.000 But what's interesting is to what extent[br]just a low level component, 9:59:59.000,9:59:59.000 the spinal cord, together with the body,[br]already solves a big part 9:59:59.000,9:59:59.000 of the locomotion problem, 9:59:59.000,9:59:59.000 and you probably know it by the fact[br]that you can cut the head of the chicken, 9:59:59.000,9:59:59.000 it can still run for a while, 9:59:59.000,9:59:59.000 showing that just the lower part,[br]spinal cord and body, 9:59:59.000,9:59:59.000 already solves a big part of locomotion. 9:59:59.000,9:59:59.000 Now, understanding how this works[br]is very complex, 9:59:59.000,9:59:59.000 because first of all, 9:59:59.000,9:59:59.000 recording activity in the spinal cord[br]is very difficult. 9:59:59.000,9:59:59.000 It's much easier to implant electrodes[br]in the motor cortex 9:59:59.000,9:59:59.000 than in the spinal cord, because[br]it's protected by the vertebrae. 9:59:59.000,9:59:59.000 Especially in humans,[br]it's very hard to do. 9:59:59.000,9:59:59.000 A second difficulty is that locomotion[br]is really due to a very complex 9:59:59.000,9:59:59.000 and very dynamic interaction[br]between these four components. 9:59:59.000,9:59:59.000 So it's very hard to find out[br]what's the role of each over time. 9:59:59.000,9:59:59.000 This is where biorobots like Pleurobot[br]and mathematical models 9:59:59.000,9:59:59.000 can really help. 9:59:59.000,9:59:59.000 So what's biorobotics? 9:59:59.000,9:59:59.000 Biorobotics is a very active field[br]of research in robotics 9:59:59.000,9:59:59.000 where people want to take inspiration[br]from animals to make robots 9:59:59.000,9:59:59.000 to go outdoors, 9:59:59.000,9:59:59.000 like service robots[br]or search-and-rescue robots 9:59:59.000,9:59:59.000 or field robots, 9:59:59.000,9:59:59.000 and the big goal here is[br]to take inspiration from animals 9:59:59.000,9:59:59.000 to make robotics that can handle[br]complex terrain -- 9:59:59.000,9:59:59.000 stairs, mountains, forests, 9:59:59.000,9:59:59.000 places where robots[br]still have difficulties 9:59:59.000,9:59:59.000 and where animals can do[br]a much better job. 9:59:59.000,9:59:59.000 The robot can be[br]a wonderful scientific tool as well. 9:59:59.000,9:59:59.000 There are some very nice projects[br]where robots are used 9:59:59.000,9:59:59.000 like a scientific tool for neuroscience,[br]for biomechanics, or for ?? dynamics. 9:59:59.000,9:59:59.000 And this is exactly[br]the purpose of Pleurobot. 9:59:59.000,9:59:59.000 So what we do in my lab[br]is to collaborate with neurobiologists 9:59:59.000,9:59:59.000 like Jean-Marie Cabelguen,[br]a neurobiologist in Bordeaux in France, 9:59:59.000,9:59:59.000 and we want to make spinal cord models[br]and validate them on robots. 9:59:59.000,9:59:59.000 And here we want to start simple. 9:59:59.000,9:59:59.000 So it's good to start with simple animals 9:59:59.000,9:59:59.000 like lampreys, which are[br]very primitive fish, 9:59:59.000,9:59:59.000 and then gradually go toward[br]more complex locomotion, 9:59:59.000,9:59:59.000 like in salamanders, 9:59:59.000,9:59:59.000 but also in cats and in humans, 9:59:59.000,9:59:59.000 in mammals. 9:59:59.000,9:59:59.000 And here, a robot becomes[br]an interesting tool 9:59:59.000,9:59:59.000 to validate our models, 9:59:59.000,9:59:59.000 and in fact, for me, Pleurobot[br]is a kind of dream becoming true. 9:59:59.000,9:59:59.000 Like, more or less 20 years ago[br]I was already working on a computer 9:59:59.000,9:59:59.000 making simulations of lamprey[br]and salamander locomotion 9:59:59.000,9:59:59.000 during my Ph.D