[Script Info]
Title: 
[Events]
Format: Layer, Start, End, Style, Name, MarginL, MarginR, MarginV, Effect, Text
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,We all go to doctors,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and we do so with trust and blind faith
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,that the test they are ordering\Nand the medications they're prescribing
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,are based upon evidence,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,evidence that's designed to help us.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,However, the reality is
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,that that hasn't always\Nbeen the case for everyone.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,What if I told you that the medical\Nscience discovered over the past century
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,has been based on\Nonly half the population?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,I'm an emergency medicine doctor.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,I was trained to be prepared\Nin a medical emergency.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,It's about saving lives.\NHow cool is that?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,Okay, there's a lot of runny noses\Nand stubbed toes,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,but no matter who walks\Nthrough the door to the ER,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,we order the same tests,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,we prescribe the same medication
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,without ever thinking about\Nthe sex or gender of our patients.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,Why would we?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,We were never taught that there were\Nany differences between men and women.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,A recent Government Accountability study\Nrevealed that 80 percent of the drugs
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,withdrawn from the market
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,are due to side effects on women.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,So let's think about that for a minute.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,Why are we discovering\Nside effects on women
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,only after a drug has been released\Nto the market?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,Do you know that it takes years for a drug
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,to go from an idea to being tested\Non cells in a laboratory,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,to animal studies,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,to then clinical trials on humans,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,finally to go through\Na regulatory approval process,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,to be available for your doctor\Nto prescribe to you,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,not to mention the millions\Nand billions of dollars of funding
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,it takes to go through that process.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,So why are we discovering\Nunacceptable side effects
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,on half the population\Nafter that has gone through?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,What's happening?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,Well, it turns out that those cells\Nused in that laboratory,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,they're male cells,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and the animals used\Nin the animal studies were male animals,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and the clinical trials have been\Nperformed almost exclusively on men.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,How is it that the male model became\Nour framework for medical research?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,Let's look at an example that has\Nbeen popularized in the media,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and it has to do\Nwith the sleep aid Ambien.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,Ambien was released on the market\Nover 20 years ago,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and since then, hundreds of millions\Nof prescriptions have been written,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,primarily to women because women\Nsuffer more sleep disorders than men.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,But just this past year,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,the Food and Drug Administration\Nrecommended cutting the dose in half
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,for women only,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,because they just realized\Nthat women metabolize the drug
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,at a slower rate than men,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,causing them to wake up in the morning\Nwith more of the active drug in the system
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and then they're drowsy and they're\Ngetting behind the wheel of the car,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and they're at risk\Nfor motor vehicle accidents.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,And I can't help but think,\Nas an emergency physician,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,how many of my patients\Nthat I've cared for over the years
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,that were involved\Nin a motor vehicle accident
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,possibly could have been prevented
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,if this type of analysis was performed\Nand acted upon 20 years ago
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,when this drug was first released.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,How many other things\Nneed to be analyzed by gender?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,What else are we missing?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,World War II changed a lot of things,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and one of them was this need\Nto protect people
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,from becoming victims of medical research\Nwithout informed consent.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,So some much-needed guidelines\Nor rules were set into place,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and part of that was this desire\Nto protect women of childbearing age
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,from entering into any\Nmedical research studies.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,It was fear, what if something happened\Nto the fetus during this study?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,Who would be responsible.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,And so the scientists\Nat this time actually thought
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,this was a blessing in disguise,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,because let's face it,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,men's bodies are pretty homogeneous.