1 00:00:10,025 --> 00:00:11,111 Oh the humanity! 2 00:00:13,730 --> 00:00:15,651 Ah... humanity... 3 00:00:16,210 --> 00:00:19,162 It’s a trainwreck, but I can’t look away. 4 00:00:20,206 --> 00:00:23,576 It’s 1843, and a debate is raging among physicians 5 00:00:23,576 --> 00:00:28,089 about one of the most common killers of women: childbed fever. 6 00:00:28,089 --> 00:00:31,569 Childbed fever strikes within days of giving birth, 7 00:00:31,569 --> 00:00:37,983 killing more than 70% of those infected— and nobody knows what causes it. 8 00:00:37,983 --> 00:00:41,846 Obstetrician Charles Meigs has a theory. 9 00:00:41,846 --> 00:00:43,928 Having observed abdominal inflammation 10 00:00:43,928 --> 00:00:46,498 in patients who go on to develop the fever, 11 00:00:46,498 --> 00:00:51,114 he claims this inflammation is the cause of childbed fever. 12 00:00:51,114 --> 00:00:54,954 Much of the medical establishment supports his theory. 13 00:00:54,954 --> 00:00:56,424 Oh, come on! 14 00:00:56,424 --> 00:01:01,114 They really leave me no choice but to teach them some skepticism. 15 00:01:12,891 --> 00:01:13,959 That’s better. 16 00:01:14,871 --> 00:01:21,687 Now, Meigs, your argument is based on a fallacy— the false cause fallacy. 17 00:01:21,687 --> 00:01:25,687 Correlation does not imply causation: 18 00:01:25,687 --> 00:01:28,927 When two phenomena regularly occur together, 19 00:01:28,927 --> 00:01:33,725 one does not necessarily cause the other. 20 00:01:33,725 --> 00:01:39,666 So you say women who have inflammation also come down with childbed fever, 21 00:01:39,666 --> 00:01:43,666 therefore the inflammation caused the fever. 22 00:01:43,666 --> 00:01:46,966 But that’s not necessarily true. 23 00:01:46,966 --> 00:01:51,116 Yes, yes, the inflammation comes first, then the fever, 24 00:01:51,116 --> 00:01:55,116 so it seems like the inflammation causes the fever. 25 00:01:55,116 --> 00:02:00,400 But by that logic, since babies usually grow hair before teeth, 26 00:02:00,400 --> 00:02:03,630 hair growth must cause tooth growth. 27 00:02:03,630 --> 00:02:06,460 And we all know that’s not true, right? 28 00:02:06,460 --> 00:02:08,280 Actually, don’t answer that. 29 00:02:08,280 --> 00:02:11,991 A couple of different things could be going on here. 30 00:02:11,991 --> 00:02:16,668 First, it’s possible that fever and inflammation are correlated 31 00:02:16,668 --> 00:02:19,588 purely by coincidence. 32 00:02:19,588 --> 00:02:25,627 Or, there could be a causal relationship that’s the opposite of what you think— 33 00:02:25,627 --> 00:02:28,627 the fever causes the inflammation, 34 00:02:28,627 --> 00:02:31,747 rather than the inflammation causing the fever. 35 00:02:31,747 --> 00:02:38,535 Or both could share a common underlying cause you haven’t thought of. 36 00:02:38,535 --> 00:02:46,059 If I may, just what do you think causes inflammation? Nothing? 37 00:02:46,059 --> 00:02:49,519 It just is? Really? 38 00:02:49,519 --> 00:02:54,257 Humor me for a moment in discussing one of your colleague’s ideas— 39 00:02:54,257 --> 00:02:56,847 Dr. Oliver Wendell Holmes. 40 00:02:56,847 --> 00:03:00,157 I know, I know, you don’t like his theory— 41 00:03:00,157 --> 00:03:03,377 you already wrote a scathing letter about it. 42 00:03:03,377 --> 00:03:06,477 But let’s fill your students in, shall we? 43 00:03:06,477 --> 00:03:12,289 Holmes noticed a pattern: when a patient dies of childbed fever, 44 00:03:12,289 --> 00:03:15,199 a doctor performs an autopsy. 45 00:03:15,199 --> 00:03:18,599 If the doctor then treats a new patient, 46 00:03:18,599 --> 00:03:22,599 that patient often comes down with the fever. 47 00:03:22,599 --> 00:03:24,094 Based on this correlation 48 00:03:24,094 --> 00:03:29,384 between autopsies of fever victims and new fever patients, 49 00:03:29,384 --> 00:03:32,150 he proposes a possible cause. 50 00:03:32,150 --> 00:03:38,705 Since there’s no evidence that the autopsy causes the fever beyond this correlation, 51 00:03:38,705 --> 00:03:43,774 he doesn’t jump to the conclusion that autopsy causes fever. 52 00:03:43,774 --> 00:03:49,230 Instead, he suggests that doctors are infecting their patients 53 00:03:49,230 --> 00:03:54,922 via an invisible contaminant on their hands and surgical instruments. 54 00:03:54,922 --> 00:04:00,750 This idea outrages most doctors, who see themselves as infallible. 55 00:04:00,750 --> 00:04:04,880 Like Meigs here, who refuses to consider the possibility 56 00:04:04,880 --> 00:04:08,440 that he’s playing a role in his patients’ plight. 57 00:04:08,440 --> 00:04:13,523 His flawed argument doesn’t leave any path forward for further investigation— 58 00:04:13,523 --> 00:04:15,743 but Holmes’ does. 59 00:04:24,222 --> 00:04:27,492 It’s 1847, and physician Ignaz Semmelweis 60 00:04:27,492 --> 00:04:29,752 has reduced the number of childbed fever deaths 61 00:04:29,752 --> 00:04:34,832 in a clinic from 12% to 1% by requiring all medical personnel 62 00:04:34,832 --> 00:04:40,162 to disinfect their hands after autopsies and between patient examinations. 63 00:04:40,162 --> 00:04:45,252 With this initiative, he has proven the contagious nature of childbed fever. 64 00:04:45,552 --> 00:04:46,692 Ha! 65 00:04:50,368 --> 00:04:53,845 It’s 1879, and Louis Pasteur has identified 66 00:04:53,845 --> 00:04:58,371 the contaminant responsible for many cases of childbed fever: 67 00:04:58,371 --> 00:05:01,411 Hemolytic streptococcus bacteria. 68 00:05:04,301 --> 00:05:07,151 Hmm, my fries are cold. 69 00:05:07,151 --> 00:05:10,501 Must be because my ice cream melted.