[Script Info]
Title: 
[Events]
Format: Layer, Start, End, Style, Name, MarginL, MarginR, MarginV, Effect, Text
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,Chris Anderson: So I guess\Nwhat we're going to do is
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,we're going to talk about your life,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and using some pictures\Nthat you shared with me.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,And I think we should start\Nright here with this one.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,Okay, now who is this?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,Martine Rothblatt: This is me
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,with our oldest son Eli.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,He was about age five.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,This is taken in Nigeria
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,right after having taken\Nthe Washington, DC bar exam.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: Okay. But this doesn't\Nreally look like a Martine.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: Right. That was myself as a male,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,the way I was brought up,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,before I transitioned
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,from male to female and Martin to Martine.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: You were brought up Martin Rothblatt.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: Correct.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: And about a year after this picture,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,you married a beautiful woman.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,Was this love at first sight?\NWhat happened there?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: It was love at the first sight.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,I saw Bina at a discotheque\Nin Los Angeles,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and we later began living together,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,but the moment I saw her,\NI saw just an aura of energy around her.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,I asked her to dance.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,She said she saw an aura\Nof energy around me.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,I was a single male parent.\NShe was a single female parent.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,We showed each other\Nour kids' pictures,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and we've been happily married\Nfor a third of a century now.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,(Applause)
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: And at the time, you were\Nkind of this hotshot entrepreneur,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,working with satellites.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,I think you had two successful companies,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and then you started\Naddressing this problem
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,of how could you use satellites
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,to revolutionize radio.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,Tell us about that.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: Right. I always\Nloved space technology,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and satellites, to me, are sort of\Nlike the canoes that our ancestors
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,first pushed out into the water.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,So it was exciting for me\Nto be part of the navigation
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,of the oceans of the sky,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and as I developed different types\Nof satellite communication systems,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,the main thing I did was to launch
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,bigger and more powerful satellites,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,the consequence was that\Nthe receiving antennas
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,could be smaller and smaller,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and after going through\Ndirect television broadcasting,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,I had the idea that if we could make
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,a more powerful satellite,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,the receiving dish could be so small
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,that it would just be a section\Nof a parabolic dish,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,a flap of a plate embedded\Ninto the roof of an automobile,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and it would be possible to have\Nnationwide satellite radio,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and that's SiriusXM today.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: Wow. So who here has used Sirius?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,(Applause)
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: Thank you for\Nyour monthly subscriptions.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,(Laughter)
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: So that succeeded despite\Nall predictions at the time.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,It was a huge commercial success,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,but soon after this, in the early 1990s,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,there was this big transition in your life
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and you became Martine.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: Correct.\NCA: So tell me, how did that happen?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: It happened in consultation with Bina
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and our four beautiful children,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and I discussed with each of them
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,that I felt my soul was always female,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and as a woman,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,but I was afraid people would laugh at me
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,if I expressed it,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,so I always kept it bottled up
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and just showed my male side.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,And each of them\Nhad a different take on this.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,Bina said that I love your soul
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and whether the outside\Nis Martin and Martine,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,it doesn't it matter to me,\NI love your soul.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,My son said, if you become a woman,\Nwill you still be my father?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,And I said yes,\NI'll always be your father,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and I'm still his father today.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,My youngest daughter did an absolutely\Nbrilliant five-year old thing.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,She told people, "I love my dad\Nand she loves me."
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,So she had no problem\Nwith a gender blending whatsoever.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: And a couple years after this,\Nyou published this book:
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,The Apartheid of Sex.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,What was your thesis in this book?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: My thesis in this book is that there\Nare seven billion people in the world,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and actually, seven billion unique ways\Nto express one's gender.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,And while people may have\Nthe genitals of a male or a female,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,the genitals don't determine your gender
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,or even really your sexual identity.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,That's just a matter of anatomy
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and reproductive tracts,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and people could choose\Nwhatever gender they want
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,if they weren't forced by society
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,into categories of either male or female
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,the way South Africa used to force people
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,into categories of black or white.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,We know from anthropological science
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,that race is fiction,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,even though racism is very, very real,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and we now know from cultural studies
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,that separate male or female genders
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,is a constructed fiction.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,The reality is a gender fluidity
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,that crosses the entire continuum\Nfrom male to female.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: You yourself don't always\Nfeel 100 percent female.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: Correct. I would say in some ways
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,I change my gender about as often\Nas I change my hairstyle.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: (Laughs) Okay, now, this is\Nyour gorgeous daughter, Genesis.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,And I guess she was about this age
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,when something pretty terrible happened.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: Yes, she was finding herself\Nunable to walk up the stairs
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,in our house to her bedroom,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and after several months of doctors,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,she was diagnosed to have a rare,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,almost invariably fatal disease
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,called pulmonary arterial hypertension.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: So how did you respond to that?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: Well, we first tried to get her\Nto the best doctors we could.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,We ended up at Children's\NNational Medical Center in Washington, DC.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,The head of pediatric cardiology
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,told us that he was going to refer her\Nto get a lung transplant,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,but not to hold out any hope,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,because there are\Nvery few lungs available,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,especially for children.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,He said that all people\Nwith this illness die,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and if any of you have seen\Nthe film "Lorenzo's Oil,"
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,there's a scene when the protagonist
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,kind of rolls down the stairway\Ncrying and bemoaning the fate of his son,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and that's exactly\Nhow we felt about Genesis.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: But you didn't accept that\Nas the limit of what you could do.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,You started trying to research
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and see if you could find a cure somehow.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: Correct. She was in intensive\Ncare ward for weeks at a time,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and Bina and I would tag team\Nto stay at the hospital
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,while the other watched\Nthe rest of the kids,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and when I was in the hospital\Nand she was sleeping,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,I went to the hospital library.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,I read every article that I could find\Non pulmonary hypertension.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,I had not taken any biology,\Neven in college,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,so I had to go from a biology textbook
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,to a college-level textbook
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and then medical textbook\Nand the journal articles, back and forth,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and eventually I knew enough to think\Nthat it might be possible
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,that somebody could find a cure.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,So we started a nonprofit foundation.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,I wrote a description
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,asking people to submit grants
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and we would pay for medical research.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,I became an expert on the condition.\NDoctors said to me, Martine,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,we really appreciate all the funding\Nyou've provided us,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,but we are not going to be able\Nto find a cure in time
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,to save your daughter.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,However, there is a medicine
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,that was developed at the\NBorroughs Wellcome Trust Company
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,that could halt the progression\Nof the disease,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,but Borroughs Wellcome has just\Nbeen acquired by Glaxo Wellcome.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,They made a decision not to develop
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,any medicines for rare\Nand orphan diseases,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and maybe you could use your expertise\Nin satellite communications
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,to develop this cure\Nfor pulmonary hypertension.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: So how on earth did you get\Naccess to this drug?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: I went to Glaxo Wellcome
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and after three times being rejected\Nand having the door slammed in my face
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,because they weren't going\Nto out-license the drug
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,to a satellite communications expert,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,they weren't going to send the drug\Nout to anybody at all,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and they thought\NI didn't have the expertise,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,finally I was able to persuade\Na small team of people to work with me
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and develop enough credibility.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,I wore down their resistance,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and they had no hope this drug\Nwould even work, by the way,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and they tried to tell me,\N"You're just wasting your time.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,We're sorry about your daughter."
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,But finally, for 25,000 dollars
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and agreement to pay 10 percent\Nof any revenues we might ever get,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,they agreed to give me\Nworldwide rights to this drug.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: And so you put this drug on the market
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,in a really brilliant way,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,by basically charging what it would take\Nto make the economics work.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: Oh yes, Chris, but this really wasn't\Na drug that I ended up,\N
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,after I wrote the check for 25,000,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and I said, "Okay, where's\Nthe medicine for Genesis?"
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,they said, "Oh, Martine,\Nthere's no medicine for Genesis.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,This is just something we tried in rats."
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,And they gave me, like,\Na little plastic Ziploc bag
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,of a small amount of powder.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,They said, "Don't give it to any human,"
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and they gave me a piece of paper\Nwhich said it was a patent,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and from that, we had to figure out\Na way to make this medicine.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,A hundred chemists in the U.S.\Nat the top universities
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,all swore that little patent\Ncould never be turned into a medicine.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,If it was turned into a medicine,\Nit could never be delivered
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,because it had a half life\Nof only 45 minutes.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: And yet, a year or two later,\Nyou were there with the medicine
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,that worked for Genesis.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: Chris, the astonishing thing\Nis that this absolutely worthless
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,piece of powder
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,that had the sparkle of a promise\Nof hope for Genesis
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,is not only keeping Genesis\Nand other people alive today,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,but produces almost a billion\Nand a half dollars a year in revenue.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,(Applause)
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: So here you go.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,So you took this company public, right?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,And made an absolute fortune.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,And how much have you paid Glaxo,\Nby the way, after that 25,000?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: Yeah, well every year we pay them\N10 percent of 1.5 billion,,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,150 million dollars,\Nlast year a hundred million dollars.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,The best return on an investment\Nthey ever received.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: And the best news of all, I guess,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,is this.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,Mr: Yes. Genesis is an absolutely\Nbrilliant young lady.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,She's alive, healthy today at 30.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,You see me, Bina, and Genesis there.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,She's, the most amazing\Nthing about Genesis
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,is that while she could do\Nanything with her life,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and believe me, if you grew up\Nyour whole life with people
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,in your face saying\Nthat you've got a fatal disease,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,I would probably run to Tahiti and just\Nnot want to run into anybody again.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,But instead she chooses to work\Nin United Therapeutics.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,She says she wants to do all she can\Nto help other people
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,with orphan diseases get medicines,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and today, she's our project leader\Nfor all telepresence activities,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,where she helps digitally unite\Nthe entire company to work together
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,to find cures for pulmonary hypertension.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: But not everyone who has this disease\Nhas been so fortunate.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,There are still many people dying,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,and you are tackling that too. How?
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,MR: Exactly, Chris. There's some 3,000\Npeople a year in the United States alone,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,perhaps ten times that number worldwide,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,who continue to die of this illness
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,because the medicines\Nslow down the progression
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,but they don't halt it.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,The only cure for pulmonary hypertension,\Npulmonary fibrosis,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,cystic fibrosis, emphysema,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,COPD, what Leonard Nimoy just died of,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,is a lung transplant,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,but sadly, there are only enough\Navailable lungs for 2,000 people
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,in the U.S. a year\Nto get a young transplant,
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,whereas nearly a half\Nmillion people a year
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,die of end stage lung failure.
Dialogue: 0,9:59:59.99,9:59:59.99,Default,,0000,0000,0000,,CA: So how can you address that?