1 00:00:06,170 --> 00:00:08,790 Vismita Gupta-Smith: Hello, and welcome to Science in 5. 2 00:00:08,790 --> 00:00:10,720 I'm Vismita Gupta-Smith. 3 00:00:10,720 --> 00:00:14,824 We are talking today about the Delta variant and vaccines. 4 00:00:14,968 --> 00:00:19,745 Dr. Soumya Swaminathan, WHO's Chief Scientist is our expert today. 5 00:00:19,780 --> 00:00:20,940 Welcome, Soumya. 6 00:00:21,010 --> 00:00:23,071 Our first question to you, Soumya, 7 00:00:23,071 --> 00:00:26,833 is we know that the Delta variant is more transmissible. 8 00:00:27,039 --> 00:00:30,587 Please explain to us what kind of protection 9 00:00:30,587 --> 00:00:34,109 we get from the current batch of approved vaccines. 10 00:00:34,109 --> 00:00:37,204 Soumya Swaminathan: So we're talking here about the Delta variant, 11 00:00:37,204 --> 00:00:39,171 which is the fourth variant of concern 12 00:00:39,171 --> 00:00:40,678 described by WHO 13 00:00:40,678 --> 00:00:44,512 because it's both more transmissible than the previous variant 14 00:00:44,512 --> 00:00:50,484 and also has been able to resist the antibodies that we have in our blood. 15 00:00:50,484 --> 00:00:53,966 So what that means is that you need a higher level of antibodies 16 00:00:53,966 --> 00:00:55,561 to overcome this variant 17 00:00:55,561 --> 00:00:58,489 as compared to, let's say, the Alpha variant. 18 00:00:59,049 --> 00:01:05,202 Now, the good news is that all of the WHO emergency use listed vaccines 19 00:01:05,202 --> 00:01:09,233 do protect against developing severe disease, 20 00:01:09,233 --> 00:01:12,178 hospitalization and death due to the Delta variant. 21 00:01:12,178 --> 00:01:13,319 So there are studies now 22 00:01:13,319 --> 00:01:16,453 from countries where there is a predominance of Delta variant 23 00:01:16,453 --> 00:01:19,049 to show that people who've been vaccinated 24 00:01:19,049 --> 00:01:23,243 are much less likely to end up in hospital. 25 00:01:23,500 --> 00:01:26,028 And you need the full course of vaccination 26 00:01:26,028 --> 00:01:30,347 in order to give you that full immunity to protect you against the Delta variant. 27 00:01:30,489 --> 00:01:31,879 So the important thing is 28 00:01:31,879 --> 00:01:36,743 if you have access to a vaccine that's approved by WHO, 29 00:01:36,743 --> 00:01:38,878 please do take it and take the full course 30 00:01:38,878 --> 00:01:40,219 so that you can be protected 31 00:01:40,219 --> 00:01:43,521 both against the Delta and other variants of COVID. 32 00:01:43,570 --> 00:01:47,791 VGS: Soumya, explain to us, please, the level of protection that you have 33 00:01:47,791 --> 00:01:51,219 if you have received one dose of the vaccine 34 00:01:51,219 --> 00:01:53,230 versus if you're fully vaccinated. 35 00:01:53,230 --> 00:01:57,912 SS: So the main goal of these vaccines is really to prevent severe disease 36 00:01:57,912 --> 00:02:02,057 because what we want is for people, even if they get the infection, 37 00:02:02,057 --> 00:02:05,994 is for them to recover from it and not become seriously ill. 38 00:02:06,480 --> 00:02:10,679 So that's something that all of these vaccines do really well. 39 00:02:10,679 --> 00:02:12,490 Of course, there are different levels. 40 00:02:12,490 --> 00:02:14,396 You read about the efficacy trials. 41 00:02:14,396 --> 00:02:16,991 They may range from 70% to 90%. 42 00:02:17,240 --> 00:02:20,240 But in terms of just looking at the prevention of severe disease 43 00:02:20,240 --> 00:02:21,244 and hospitalization, 44 00:02:21,244 --> 00:02:24,138 they're all very good, over 90% effective. 45 00:02:24,616 --> 00:02:28,102 Again, they vary in the protection against getting an infection. 46 00:02:28,289 --> 00:02:30,924 Ideally, you know, you'd like a vaccine 47 00:02:30,924 --> 00:02:33,664 which completely prevents you from getting infected, 48 00:02:33,664 --> 00:02:35,250 therefore you can't get ill. 49 00:02:35,540 --> 00:02:37,862 But none of the vaccines that we have currently 50 00:02:37,862 --> 00:02:39,624 are 100% protective. 51 00:02:39,780 --> 00:02:44,884 So this is why even if you're vaccinated, you can get the infection, 52 00:02:44,884 --> 00:02:48,401 but the chances are you'll get very mild symptoms 53 00:02:48,401 --> 00:02:49,912 or no symptoms at all, 54 00:02:49,912 --> 00:02:52,208 and that the chances of getting seriously ill 55 00:02:52,208 --> 00:02:53,411 are really, really low. 56 00:02:53,411 --> 00:02:56,440 VGS: So Soumya, if we can still get infected 57 00:02:56,440 --> 00:03:01,092 and also infect others even after we are fully vaccinated, 58 00:03:01,092 --> 00:03:02,739 then why get vaccinated? 59 00:03:02,819 --> 00:03:05,512 SS: There are two very good reasons to get vaccinated. 60 00:03:05,699 --> 00:03:08,800 The first is to protect yourself from getting severely ill 61 00:03:08,800 --> 00:03:10,090 if you catch the infection. 62 00:03:10,090 --> 00:03:13,622 We know that there's a certain proportion of people of all age groups 63 00:03:13,622 --> 00:03:14,845 who do get severely ill 64 00:03:14,845 --> 00:03:18,030 and, you know, you could have a chance of dying from this disease, 65 00:03:18,030 --> 00:03:19,742 and this is what we want to protect. 66 00:03:19,742 --> 00:03:23,031 So that's why you want to get vaccinated in the first place. 67 00:03:23,280 --> 00:03:27,967 But secondly, if you get vaccinated and yes, you may still get the infection 68 00:03:27,967 --> 00:03:31,311 because we know that these vaccines are not going to protect you a 100% 69 00:03:31,311 --> 00:03:32,321 from the infection. 70 00:03:32,321 --> 00:03:34,470 So there is a small risk you get infected, 71 00:03:34,470 --> 00:03:36,215 and you could pass it on to others. 72 00:03:36,419 --> 00:03:38,606 Why do you want to take the risk of doing that? 73 00:03:38,606 --> 00:03:41,873 Why do you want to be one person in the chain of transmission? 74 00:03:42,080 --> 00:03:45,808 What we need to do in the world today is to break those chains of transmission, 75 00:03:45,808 --> 00:03:47,736 get control of this disease. 76 00:03:47,879 --> 00:03:49,482 So that's why we say 77 00:03:49,482 --> 00:03:52,498 get vaccinated as soon as you can get access to your vaccine 78 00:03:52,498 --> 00:03:53,760 when your turn comes, 79 00:03:53,760 --> 00:03:56,151 and continue to take all the precautions 80 00:03:56,151 --> 00:03:59,286 so that you are completely protecting yourself 81 00:03:59,286 --> 00:04:01,400 as well as protecting others around you. 82 00:04:01,680 --> 00:04:02,810 VGS: Thank you, Soumya. 83 00:04:02,810 --> 00:04:04,371 That was Science in 5 today. 84 00:04:04,371 --> 00:04:05,705 Until next time then. 85 00:04:05,705 --> 00:04:09,270 Stay safe. Stay healthy, and stick with science. 86 00:04:09,270 --> 00:04:11,963 Subtitles by MaurĂ­cio Kakuei Tanaka Review by Carol Wang