WEBVTT 00:00:06.513 --> 00:00:07.893 Across the whole planet, 00:00:07.893 --> 00:00:14.022 humans eat on average between one and 2.7 kilograms of food a day. 00:00:14.022 --> 00:00:17.534 That's over 365 kilograms a year per person, 00:00:17.534 --> 00:00:23.072 and more than 28,800 kilograms over the course of a lifetime. 00:00:23.072 --> 00:00:27.384 And every last scrap makes its way through the digestive system. 00:00:27.384 --> 00:00:30.103 Comprised of ten organs covering nine meters 00:00:30.103 --> 00:00:33.423 and containing over 20 specialized cell types, 00:00:33.423 --> 00:00:38.123 this is one of the most diverse and complicated systems in the human body. 00:00:38.123 --> 00:00:42.693 Its parts continuously work in unison to fulfill a singular task: 00:00:42.693 --> 00:00:45.393 transforming the raw materials of your food 00:00:45.393 --> 00:00:48.914 into the nutrients and energy that keep you alive. 00:00:48.914 --> 00:00:51.384 Spanning the entire length of your torso, 00:00:51.384 --> 00:00:54.705 the digestive system has four main components. 00:00:54.705 --> 00:00:57.594 First, there's the gastrointestinal tract, 00:00:57.594 --> 00:00:59.995 a twisting channel that transports your food 00:00:59.995 --> 00:01:05.625 and has an internal surface area of between 30 and 40 square meters, 00:01:05.625 --> 00:01:08.589 enough to cover half a badminton court. 00:01:08.589 --> 00:01:09.977 Second, there's the pancreas, 00:01:09.977 --> 00:01:10.893 gallbladder, 00:01:10.893 --> 00:01:11.678 and liver, 00:01:11.678 --> 00:01:16.504 a trio of organs that break down food using an array of special juices. 00:01:16.504 --> 00:01:18.472 Third, the body's enzymes, 00:01:18.472 --> 00:01:19.253 hormones, 00:01:19.253 --> 00:01:19.996 nerves, 00:01:19.996 --> 00:01:20.727 and blood 00:01:20.727 --> 00:01:23.203 all work together to break down food, 00:01:23.203 --> 00:01:25.093 modulate the digestive process, 00:01:25.093 --> 00:01:28.077 and deliver its final products. 00:01:28.077 --> 00:01:29.776 Finally, there's the mesentery, 00:01:29.776 --> 00:01:32.095 a large stretch of tissue that supports 00:01:32.095 --> 00:01:35.854 and positions all your digestive organs in the abdomen, 00:01:35.854 --> 00:01:37.833 enabling them to do their jobs. 00:01:37.833 --> 00:01:42.153 The digestive process begins before food even hits your tongue. 00:01:42.153 --> 00:01:44.184 Anticipating a tasty morsel, 00:01:44.184 --> 00:01:47.644 glands in your mouth start to pump out saliva. 00:01:47.644 --> 00:01:52.134 We produce about 1.5 liters of this liquid each day. 00:01:52.134 --> 00:01:53.575 Once inside your mouth, 00:01:53.575 --> 00:01:56.055 chewing combines with the sloshing saliva 00:01:56.055 --> 00:02:00.873 to turn food into a moist lump called the bolus. 00:02:00.873 --> 00:02:04.550 Enzymes present in the saliva break down any starch. 00:02:04.550 --> 00:02:06.225 Then, your food finds itself 00:02:06.225 --> 00:02:10.986 at the rim of a 25 centimeter-long tube called the esophagus, 00:02:10.986 --> 00:02:14.314 down which it must plunge to reach the stomach. 00:02:14.314 --> 00:02:16.726 Nerves in the surrounding esophageal tissue 00:02:16.726 --> 00:02:20.268 sense the bolus's presence and trigger peristalsis, 00:02:20.268 --> 00:02:23.155 a series of defined muscular contractions. 00:02:23.155 --> 00:02:25.905 That propels the food into the stomach 00:02:25.905 --> 00:02:29.537 where it's left at the mercy of the muscular stomach walls, 00:02:29.537 --> 00:02:32.886 which bound the bolus, breaking it into chunks. 00:02:32.886 --> 00:02:37.016 Hormones secreted by cells in the lining trigger the release of acids 00:02:37.016 --> 00:02:39.936 and enzyme-rich juices from the stomach wall 00:02:39.936 --> 00:02:43.517 that start to dissolve the food and break down its proteins. 00:02:43.517 --> 00:02:45.988 These hormones also alert the pancreas, 00:02:45.988 --> 00:02:46.695 liver, 00:02:46.695 --> 00:02:47.767 and gallbladder 00:02:47.767 --> 00:02:49.717 to produce digestive juices 00:02:49.717 --> 00:02:53.815 and transfer bile, a yellowish-green liquid that digests fat, 00:02:53.815 --> 00:02:56.427 in preparation for the next stage. 00:02:56.427 --> 00:02:58.450 After three hours inside the stomach, 00:02:58.450 --> 00:03:02.957 the once shapely bolus is now a frothy liquid called chyme, 00:03:02.957 --> 00:03:05.714 and it's ready to move into the small intestine. 00:03:05.714 --> 00:03:08.237 The liver receives bile from the gallbladder 00:03:08.237 --> 00:03:13.769 and secretes it into the first portion of the small intestine called the duodenum. 00:03:13.769 --> 00:03:17.778 Here, it dissolves the fats floating in the slurry of chyme 00:03:17.778 --> 00:03:22.238 so they can be easily digested by the pancreatic and intestinal juices 00:03:22.238 --> 00:03:24.467 that have leached onto the scene. 00:03:24.467 --> 00:03:29.528 These enzyme-rich juices break the fat molecules down into fatty acids 00:03:29.528 --> 00:03:33.217 and glycerol for easier absorption into the body. 00:03:33.217 --> 00:03:35.889 The enzymes also carry out the final deconstruction 00:03:35.889 --> 00:03:38.559 of proteins into amino acids 00:03:38.559 --> 00:03:40.759 and carbohydrates into glucose. 00:03:40.759 --> 00:03:43.900 This happens in the small intestine's lower regions, 00:03:43.900 --> 00:03:45.888 the jejunum and ileum, 00:03:45.888 --> 00:03:49.877 which are coated in millions of tiny projections called villi. 00:03:49.877 --> 00:03:54.410 These create a huge surface area to maximize molecule absorption 00:03:54.410 --> 00:03:56.991 and transference into the blood stream. 00:03:56.991 --> 00:03:59.650 The blood takes them on the final leg of their journey 00:03:59.650 --> 00:04:02.450 to feed the body's organs and tissues. 00:04:02.450 --> 00:04:04.331 But it's not over quite yet. 00:04:04.331 --> 00:04:05.669 Leftover fiber, 00:04:05.669 --> 00:04:06.401 water, 00:04:06.401 --> 00:04:09.300 and dead cells sloughed off during digestion 00:04:09.300 --> 00:04:13.390 make it into the large intestine, also known as the colon. 00:04:13.390 --> 00:04:17.421 The body drains out most of the remaining fluid through the intestinal wall. 00:04:17.421 --> 00:04:20.029 What's left is a soft mass called stool. 00:04:20.029 --> 00:04:24.031 The colon squeezes this byproduct into a pouch called the rectum, 00:04:24.031 --> 00:04:26.200 where nerves sense it expanding 00:04:26.200 --> 00:04:29.193 and tell the body when it's time to expel the waste. 00:04:29.193 --> 00:04:32.041 The byproducts of digestion exit through the anus 00:04:32.041 --> 00:04:33.470 and the food's long journey, 00:04:33.470 --> 00:04:36.521 typically lasting between 30 and 40 hours, 00:04:36.521 --> 00:04:38.190 is finally complete.