0:00:07.051,0:00:09.603 The discovery of the structure of DNA 0:00:09.603,0:00:14.170 was one of the most important scientific[br]achievements in the last century, 0:00:14.170,0:00:16.224 in human history, in fact. 0:00:16.224,0:00:20.163 The now-famous double helix is almost[br]synonymous with Watson and Crick, 0:00:20.163,0:00:24.327 two of the scientists who won[br]the Nobel Prize for figuring it out. 0:00:24.327,0:00:26.442 But there's another name [br]you may know, too, 0:00:26.442,0:00:28.382 Rosalind Franklin. 0:00:28.382,0:00:32.567 You may have heard that her data supported[br]Watson and Crick's brilliant idea, 0:00:32.567,0:00:36.850 or that she was a plain-dressing,[br]belligerent scientist, 0:00:36.850,0:00:41.859 which is how Watson actually described her[br]in the Double Helix. 0:00:41.859,0:00:43.852 But thanks to Franklin's biographers, 0:00:43.852,0:00:47.191 who investigated her life [br]and interviewed many people close to her, 0:00:47.191,0:00:50.917 we now know that that account[br]is far from true, 0:00:50.917,0:00:54.851 and her scientific contributions[br]have been vastly underplayed. 0:00:54.851,0:00:56.721 Let's hear the real story. 0:00:56.721,0:01:01.475 Rosalind Elsie Franklin was born[br]in London in 1920. 0:01:01.475,0:01:04.612 She wanted to be a scientist ever[br]since we was a teenager, 0:01:04.612,0:01:08.764 which wasn't a common or easy[br]career path for girls at that time. 0:01:08.764,0:01:11.039 But she excelled at science anyway. 0:01:11.039,0:01:14.325 She won a scholarship to Cambridge[br]to study chemistry, 0:01:14.325,0:01:16.112 where she earned her Ph.D., 0:01:16.112,0:01:19.397 and she later conducted research on[br]the structure of coal 0:01:19.397,0:01:23.700 that led to better gas masks for [br]the British during World War II. 0:01:23.700,0:01:26.256 In 1951, she joined King's College 0:01:26.256,0:01:29.790 to use x-ray techniques to study[br]the structure of DNA, 0:01:29.790,0:01:32.414 then one of the hottest topics in science. 0:01:32.414,0:01:35.449 Franklin upgraded the x-ray lab[br]and got to work 0:01:35.449,0:01:40.120 shining high-energy x-rays [br]on tiny, wet crystals of DNA. 0:01:40.120,0:01:43.804 But the acadmemic culture at the time[br]wasn't very friendly to women, 0:01:43.804,0:01:46.286 and Fraklin was isolated [br]from her colleagues. 0:01:46.286,0:01:48.609 She clashed with Maurice Wilkins, 0:01:48.609,0:01:52.974 a labmate who assumed Franklin[br]had been hired as his assistant. 0:01:52.974,0:01:54.472 But Franklin kept working, 0:01:54.472,0:02:01.193 and in 1952, she obtained Photo 51,[br]the most famous x-ray image of DNA. 0:02:01.193,0:02:03.630 Just getting the image took 100 hours, 0:02:03.630,0:02:07.485 the calculations necessary to analyze it[br]would take a year. 0:02:07.485,0:02:10.448 Meanwhile, the American biologist[br]James Watson 0:02:10.448,0:02:12.787 and the British physicist Francis Crick 0:02:12.787,0:02:15.730 were also working [br]on finding DNA's structure. 0:02:15.730,0:02:17.252 Without Franklin's knowledge, 0:02:17.252,0:02:21.667 Wilkins took Photo 51[br]and showed it to Watson and Crick. 0:02:21.667,0:02:25.078 Instead of calculating the exact[br]position of every atom, 0:02:25.078,0:02:27.942 they did a quick analysis [br]of Franklin's data 0:02:27.942,0:02:31.442 and used that to build [br]a few potential structures. 0:02:31.442,0:02:34.220 Eventually, they arrived at the right one. 0:02:34.220,0:02:37.169 DNA is made of two helicoidal strands, 0:02:37.169,0:02:42.416 one opposite the other with bases[br]in the center like rungs of a ladder. 0:02:42.416,0:02:46.670 Watson and Crick published their model[br]in April 1953. 0:02:46.670,0:02:50.215 Meanwhile, [br]Franklin had finished her calculations, 0:02:50.215,0:02:51.664 comes to the same conclusion, 0:02:51.664,0:02:54.398 and submitted her own manuscript. 0:02:54.398,0:02:56.721 The journal published [br]the manuscripts together, 0:02:56.721,0:02:58.883 but put Franklin's last, 0:02:58.883,0:03:02.882 making it look like her experiments just[br]confirmed Watson and Crick's breakthrough 0:03:02.882,0:03:05.381 instead of inspiring it. 0:03:05.381,0:03:07.920 But Franklin had already [br]stopped working on DNA 0:03:07.920,0:03:11.018 and died of cancer in 1958, 0:03:11.018,0:03:15.107 never knowing that Watson and Crick[br]had seen her photographs. 0:03:15.107,0:03:19.326 Watson, Crick, and Wilkins won[br]the Nobel Prize in 1962 0:03:19.326,0:03:21.421 for their work on DNA. 0:03:21.421,0:03:25.006 It's often said that Franklin would have[br]been recognized by a Nobel Prize 0:03:25.006,0:03:28.288 if only they could be [br]awarded posthumously. 0:03:28.288,0:03:31.638 And in fact, it's possible [br]she could have won twice. 0:03:31.638,0:03:37.302 Her work on the structure of viruses[br]led to a Nobel for a colleague in 1982. 0:03:37.302,0:03:42.636 It's time to tell the story of a brave[br]woman who fought sexism in science, 0:03:42.636,0:03:47.514 and whose work revolutionized[br]medicine, biology, and agriculture. 0:03:47.514,0:03:51.039 It's time to honor [br]Rosalind Elsie Franklin, 0:03:51.039,0:03:53.534 the unsung mother of the double helix.