1 00:00:00,000 --> 00:00:02,475 [MUSIC PLAYING] 2 00:00:02,475 --> 00:00:03,960 3 00:00:03,960 --> 00:00:05,445 [CHEERING] 4 00:00:05,445 --> 00:00:06,939 5 00:00:06,939 --> 00:00:10,690 Few of us think about the trauma we generate in our voice boxes 6 00:00:10,690 --> 00:00:14,210 when we talk, sing, laugh, or scream. 7 00:00:14,210 --> 00:00:15,130 [CHEERING] 8 00:00:15,130 --> 00:00:16,050 9 00:00:16,050 --> 00:00:18,310 But take a look down the talented gullet 10 00:00:18,310 --> 00:00:21,486 of Steven Tyler, Aerosmith's lead singer-- 11 00:00:21,486 --> 00:00:21,985 12 00:00:21,985 --> 00:00:22,915 [SINGING] 13 00:00:22,915 --> 00:00:24,310 14 00:00:24,310 --> 00:00:28,000 --and you get a feel for why he, and millions of others, 15 00:00:28,000 --> 00:00:31,542 are wreaking havoc on a delicate instrument. 16 00:00:31,542 --> 00:00:32,485 OK. 17 00:00:32,485 --> 00:00:33,490 [INAUDIBLE] 18 00:00:33,490 --> 00:00:37,630 Tonight, as Aerosmith performs, Dr. Stephens Zeitels 19 00:00:37,630 --> 00:00:40,390 and his team from Massachusetts General Hospital, 20 00:00:40,390 --> 00:00:41,620 will get a rare treat. 21 00:00:41,620 --> 00:00:43,420 Yeah. 22 00:00:43,420 --> 00:00:46,300 With the help of special monitoring equipment, 23 00:00:46,300 --> 00:00:49,150 they'll see how this famous pair of vocal cords 24 00:00:49,150 --> 00:00:51,700 holds up to such extremes. 25 00:00:51,700 --> 00:00:53,920 Doctors Zeitels, one time for my kids, what do you-- 26 00:00:53,920 --> 00:00:56,650 what do you-- what is this monitoring? 27 00:00:56,650 --> 00:00:59,625 What we're going to be doing is looking at the vibrations 28 00:00:59,625 --> 00:01:01,750 on the skin of your neck, which is going to pick up 29 00:01:01,750 --> 00:01:02,950 the intensity of your voice. 30 00:01:02,950 --> 00:01:03,530 Mm hm. 31 00:01:03,530 --> 00:01:06,790 It's going to be picking up the loudness of your voice. 32 00:01:06,790 --> 00:01:07,300 Mm hm. 33 00:01:07,300 --> 00:01:07,930 Thank you, doctor. 34 00:01:07,930 --> 00:01:08,430 Thank you. 35 00:01:08,430 --> 00:01:09,070 Into the abyss. 36 00:01:09,070 --> 00:01:10,270 [THROAT CLEARING] 37 00:01:10,270 --> 00:01:10,770 Oh. 38 00:01:10,770 --> 00:01:13,050 Into the great beyond with doctor Zeitels. 39 00:01:13,050 --> 00:01:13,810 And that one-- 40 00:01:13,810 --> 00:01:16,700 Backstage, throughout tonight's concert, 41 00:01:16,700 --> 00:01:20,080 Zeitels will use an endoscope to examine Tyler's voice 42 00:01:20,080 --> 00:01:21,190 box up close. 43 00:01:21,190 --> 00:01:25,010 [INAUDIBLE] 44 00:01:25,010 --> 00:01:26,240 Try not to touch the sides. 45 00:01:26,240 --> 00:01:26,739 Yup. 46 00:01:26,739 --> 00:01:27,960 [THROAT CLEARING] 47 00:01:27,960 --> 00:01:28,850 That's great, Steven. 48 00:01:28,850 --> 00:01:30,630 Put your tongue out for me. 49 00:01:30,630 --> 00:01:31,520 Just breathe. 50 00:01:31,520 --> 00:01:33,356 Say hee. 51 00:01:33,356 --> 00:01:34,760 Heee-- 52 00:01:34,760 --> 00:01:38,040 It's a rare insight into what goes on in a high performance 53 00:01:38,040 --> 00:01:38,540 singer. 54 00:01:38,540 --> 00:01:40,110 Mm. 55 00:01:40,110 --> 00:01:40,610 Eh. 56 00:01:40,610 --> 00:01:43,840 Real-time measures of a performer, 57 00:01:43,840 --> 00:01:47,660 who is at the top of his game doing a live performance 58 00:01:47,660 --> 00:01:48,940 for thousands of people. 59 00:01:48,940 --> 00:01:49,510 It's a first. 60 00:01:49,510 --> 00:01:50,634 It hasn't been done before. 61 00:01:50,634 --> 00:01:51,133 62 00:01:51,133 --> 00:01:57,460 [SINGING] 63 00:01:57,460 --> 00:02:03,360 64 00:02:03,360 --> 00:02:05,850 To produce these kinds of sounds, 65 00:02:05,850 --> 00:02:08,729 Tyler's vocal chords are slamming together an average 66 00:02:08,729 --> 00:02:11,130 of 170 times a second. 67 00:02:11,130 --> 00:02:13,510 Ah. 68 00:02:13,510 --> 00:02:15,460 That's more than half a million times 69 00:02:15,460 --> 00:02:16,810 during the course of a concert. 70 00:02:16,810 --> 00:02:19,200 Ah. 71 00:02:19,200 --> 00:02:21,450 And nearly a billion times during the course 72 00:02:21,450 --> 00:02:25,230 of his 30-year professional career. 73 00:02:25,230 --> 00:02:27,270 There's no part of the human body that 74 00:02:27,270 --> 00:02:30,330 likely sees these kinds of collision forces and shearing 75 00:02:30,330 --> 00:02:33,360 stresses, which is why vocal folds essentially wear out 76 00:02:33,360 --> 00:02:34,890 over time. 77 00:02:34,890 --> 00:02:39,020 It's also why, just months earlier, damaged vocal chords 78 00:02:39,020 --> 00:02:42,680 canceled much of Aerosmith's tour. 79 00:02:42,680 --> 00:02:44,190 Tyler could barely sing-- 80 00:02:44,190 --> 00:02:45,591 81 00:02:45,591 --> 00:02:46,525 [SINGING] 82 00:02:46,525 --> 00:02:47,459 83 00:02:47,459 --> 00:02:50,270 Just breathe. 84 00:02:50,270 --> 00:02:53,590 --forcing him to undergo Zeitels' knife. 85 00:02:53,590 --> 00:02:56,410 Or laser, in this case. 86 00:02:56,410 --> 00:02:59,890 Stephen basically had a vocal bleed, which 87 00:02:59,890 --> 00:03:02,920 is very common in performers. 88 00:03:02,920 --> 00:03:06,760 Common, in fact, to many with the gift of gab. 89 00:03:06,760 --> 00:03:10,030 From attorneys to telemarketers. 90 00:03:10,030 --> 00:03:14,070 The laser surgery, which Zeitels and his team pioneered, 91 00:03:14,070 --> 00:03:20,340 works by sealing off damaged vessels to stop the bleeding. 92 00:03:20,340 --> 00:03:23,310 These aren't some Photoshop tricks you're looking at. 93 00:03:23,310 --> 00:03:25,920 This is Steven Tyler's voice box. 94 00:03:25,920 --> 00:03:29,970 And these are his fragile blood vessels disappearing. 95 00:03:29,970 --> 00:03:33,270 He was able to zap those blood vessels. 96 00:03:33,270 --> 00:03:36,700 So I go out there and just sing and hope for the best. 97 00:03:36,700 --> 00:03:40,676 [MUSIC - AEROSMITH, "DREAM ON"] 98 00:03:40,676 --> 00:03:46,000 Now, as Stephen heads on stage, his finely tuned vocal chords 99 00:03:46,000 --> 00:03:48,570 spring into action. 100 00:03:48,570 --> 00:03:51,040 And we get a front row seat. 101 00:03:51,040 --> 00:03:53,155 This is Steven Tyler outside-- 102 00:03:53,155 --> 00:03:53,928 103 00:03:53,928 --> 00:03:58,810 Anytime that I look in the mirror-- 104 00:03:58,810 --> 00:03:59,624 --and in. 105 00:03:59,624 --> 00:04:00,124 106 00:04:00,124 --> 00:04:04,580 Anytime that I look in the mirror. 107 00:04:04,580 --> 00:04:10,970 All these lines on my face getting clearer-- 108 00:04:10,970 --> 00:04:13,880 Every time we exhale, we force air 109 00:04:13,880 --> 00:04:16,940 through our two membranous vocal chords. 110 00:04:16,940 --> 00:04:19,125 When we bring them together they vibrate. 111 00:04:19,125 --> 00:04:19,625 112 00:04:19,625 --> 00:04:21,019 Dream on. 113 00:04:21,019 --> 00:04:22,420 Dream on. 114 00:04:22,420 --> 00:04:27,120 These vibrations produce sound, much like a guitar string 115 00:04:27,120 --> 00:04:28,120 after it's been plucked. 116 00:04:28,120 --> 00:04:30,530 117 00:04:30,530 --> 00:04:31,500 Dream on. 118 00:04:31,500 --> 00:04:33,900 Muscles open and close the chords, 119 00:04:33,900 --> 00:04:35,380 and change the sound's pitch. 120 00:04:35,380 --> 00:04:35,880 121 00:04:35,880 --> 00:04:38,280 Dream until your dreams come true. 122 00:04:38,280 --> 00:04:41,670 During low notes, the chords are loose and vibrate more slowly. 123 00:04:41,670 --> 00:04:43,098 124 00:04:43,098 --> 00:04:44,526 Dream on. 125 00:04:44,526 --> 00:04:45,954 Dream on. 126 00:04:45,954 --> 00:04:46,910 Dream on. 127 00:04:46,910 --> 00:04:48,200 But for those falsettos-- 128 00:04:48,200 --> 00:04:49,174 129 00:04:49,174 --> 00:04:50,150 Dream on. 130 00:04:50,150 --> 00:04:51,887 --his chords stretched to the limit-- 131 00:04:51,887 --> 00:04:52,387 132 00:04:52,387 --> 00:04:53,700 Dream on. 133 00:04:53,700 --> 00:04:56,010 --and vibrate, virtually, off the charts. 134 00:04:56,010 --> 00:05:00,560 135 00:05:00,560 --> 00:05:04,270 A surprisingly simple feat for Tyler's pliable chords. 136 00:05:04,270 --> 00:05:09,000 137 00:05:09,000 --> 00:05:11,630 I mean to go from, and woke up this morning 138 00:05:11,630 --> 00:05:13,490 on the wrong side of the bed. 139 00:05:13,490 --> 00:05:16,010 And all them things you said, and all the things I 140 00:05:16,010 --> 00:05:18,470 said, but-- and it's in that voice. 141 00:05:18,470 --> 00:05:20,740 And then, you know, of course, and I 142 00:05:20,740 --> 00:05:23,360 don't want to miss a thing, is in that voice, 143 00:05:23,360 --> 00:05:25,028 and then Dream On is Dream on. 144 00:05:25,028 --> 00:05:26,450 Dream on. 145 00:05:26,450 --> 00:05:28,609 And they've asked me before, how do 146 00:05:28,609 --> 00:05:29,900 you sing that song every night? 147 00:05:29,900 --> 00:05:32,610 Well that's one of the easiest ones for me to sing. 148 00:05:32,610 --> 00:05:34,450 [SINGING] 149 00:05:34,450 --> 00:05:36,750 150 00:05:36,750 --> 00:05:40,800 As for what translates these vocal vibrations into song, 151 00:05:40,800 --> 00:05:45,420 that happens much farther up in the throat, the mouth, 152 00:05:45,420 --> 00:05:47,880 the tongue, the nose. 153 00:05:47,880 --> 00:05:51,750 These are what put the stamp on a human sound, 154 00:05:51,750 --> 00:05:54,990 distinguishing the likes of Steven Tyler from just 155 00:05:54,990 --> 00:05:56,213 about anyone else. 156 00:05:56,213 --> 00:05:58,004 [MUSIC - AEROSMITH, "LOVE IN AN ELEVATOR"] 157 00:05:58,004 --> 00:05:58,879 Bettin' on the dice-- 158 00:05:58,879 --> 00:06:02,500 After some two hours of vocal gymnastics, 159 00:06:02,500 --> 00:06:04,960 initial data reveal that Tyler's chords 160 00:06:04,960 --> 00:06:07,375 crash together more than half a million times-- 161 00:06:07,375 --> 00:06:08,032 162 00:06:08,032 --> 00:06:09,640 I really need a girl like an open-- 163 00:06:09,640 --> 00:06:12,515 --and covered the equivalent of more than six miles. 164 00:06:12,515 --> 00:06:13,232 165 00:06:13,232 --> 00:06:14,840 [CHEERING] 166 00:06:14,840 --> 00:06:16,610 And there's no indication they'll 167 00:06:16,610 --> 00:06:18,500 be wearing out anytime soon. 168 00:06:18,500 --> 00:06:19,494 [CHEERING] 169 00:06:19,494 --> 00:06:20,488 Thank you! 170 00:06:20,488 --> 00:06:21,482 171 00:06:21,482 --> 00:06:22,476 [CHEERING] 172 00:06:22,476 --> 00:06:24,470 173 00:06:24,470 --> 00:06:28,100 Dramatic as it may be, singing is a side effect 174 00:06:28,100 --> 00:06:31,930 of a much more crucial process. 175 00:06:31,930 --> 00:06:35,680 The real reason why air passes through our mouths 176 00:06:35,680 --> 00:06:36,812 is breathing. 177 00:06:36,812 --> 00:06:37,716 [CAR HONKING] 178 00:06:37,716 --> 00:06:38,620 [BREATHING] 179 00:06:38,620 --> 00:06:41,720 We wouldn't survive much more than a couple of minutes if we 180 00:06:41,720 --> 00:06:42,220 didn't. 181 00:06:42,220 --> 00:06:43,168 182 00:06:43,168 --> 00:06:44,116 [BREATHING] 183 00:06:44,116 --> 00:06:48,520 With every inhale, our noses or mouths 184 00:06:48,520 --> 00:06:55,420 suck in about a pint of air some 20,000 times a day. 185 00:06:55,420 --> 00:06:59,510 We can follow it on its journey down the throat, passed 186 00:06:59,510 --> 00:07:03,390 the voice box, and into the windpipe, or trachea. 187 00:07:03,390 --> 00:07:07,320 As it approaches the lungs, air has a choice. 188 00:07:07,320 --> 00:07:08,820 Left or right? 189 00:07:08,820 --> 00:07:11,950 But both lungs lead to the same end. 190 00:07:11,950 --> 00:07:14,640 The lungs' bronchi divide and divide 191 00:07:14,640 --> 00:07:18,390 into thousands of smaller and smaller branches, progressively 192 00:07:18,390 --> 00:07:22,110 filtering chemicals, dust, and smoke in the air, 193 00:07:22,110 --> 00:07:26,040 until, finally, they come to an end in this pouch-like ball 194 00:07:26,040 --> 00:07:27,390 called, an alveolus. 195 00:07:27,390 --> 00:07:28,804 196 00:07:28,804 --> 00:07:31,220 [MUSIC PLAYING] 197 00:07:31,220 --> 00:07:35,870 More than 300 million of them spread across each lung 198 00:07:35,870 --> 00:07:39,020 with a combined surface area roughly a third the size 199 00:07:39,020 --> 00:07:41,420 of a tennis court. 200 00:07:41,420 --> 00:07:44,450 In less than a second, oxygen molecules 201 00:07:44,450 --> 00:07:49,400 exit the lungs here through walls just one cell thick. 202 00:07:49,400 --> 00:07:52,350 They'll then cross into a surging bloodstream, 203 00:07:52,350 --> 00:07:56,690 be whisked throughout the body, and provide precious resources 204 00:07:56,690 --> 00:08:01,340 to every one of our trillions of cells. 205 00:08:01,340 --> 00:08:04,340 Assuming air gets to this point. 206 00:08:04,340 --> 00:08:07,670 The blue, here, shows how a healthy lung empties oxygen 207 00:08:07,670 --> 00:08:10,280 into the bloodstream. 208 00:08:10,280 --> 00:08:14,420 In this smokers lung, oxygen can't empty nearly as well. 209 00:08:14,420 --> 00:08:17,360 210 00:08:17,360 --> 00:08:20,830 Then there's the exhale. 211 00:08:20,830 --> 00:08:24,310 Carbon dioxide, the waste product of breathing, 212 00:08:24,310 --> 00:08:26,460 makes the opposite journey back out. 213 00:08:26,460 --> 00:08:29,350 214 00:08:29,350 --> 00:08:32,710 Another inhale and our breathing apparatus 215 00:08:32,710 --> 00:08:37,624 offers yet another gift with delightful or disgusting 216 00:08:37,624 --> 00:08:38,124 results. 217 00:08:38,124 --> 00:08:41,049 218 00:08:41,049 --> 00:08:43,630 With every new breath, our noses can 219 00:08:43,630 --> 00:08:47,600 distinguish as many as 10,000 different odors. 220 00:08:47,600 --> 00:08:52,780 Some pleasing, some not. 221 00:08:52,780 --> 00:08:58,000 They can calm, caution, or make our mouths water, 222 00:08:58,000 --> 00:09:00,970 but the essence of any aroma, from a day 223 00:09:00,970 --> 00:09:06,660 at the beach to fresh baked bread, is pure chemistry. 224 00:09:06,660 --> 00:09:10,750 Isobutyl acetate, vanillic acid, and more than 300 225 00:09:10,750 --> 00:09:12,880 different chemicals, for example, 226 00:09:12,880 --> 00:09:17,980 come together to give chocolate its unmistakable bouquet. 227 00:09:17,980 --> 00:09:23,410 A rose, by any other name, might be phenol ethyl alcohol. 228 00:09:23,410 --> 00:09:25,990 And once fish is passed its prime, 229 00:09:25,990 --> 00:09:29,610 it owes its stench to trymethylamine, 230 00:09:29,610 --> 00:09:34,300 a byproduct of the bacteria growing inside it. 231 00:09:34,300 --> 00:09:37,820 Whatever the chemical, deep inside our noses, 232 00:09:37,820 --> 00:09:42,580 there is a small patch of about 10 million cells waiting 233 00:09:42,580 --> 00:09:45,550 to sniff it out. 234 00:09:45,550 --> 00:09:48,220 These cells carry about 1,000 different kinds 235 00:09:48,220 --> 00:09:50,920 of receptors on their surfaces. 236 00:09:50,920 --> 00:09:53,230 When the right odor chemical meets up 237 00:09:53,230 --> 00:09:56,350 with the right receptor, an electrical signal 238 00:09:56,350 --> 00:09:57,980 gets sent to the brain. 239 00:09:57,980 --> 00:10:01,030 And finally, the incredible machine, smells. 240 00:10:01,030 --> 00:10:04,430 241 00:10:04,430 --> 00:10:07,520 All in all, our respiratory systems 242 00:10:07,520 --> 00:10:12,820 are ingenious multi-taskers, sorting thousands of smells 243 00:10:12,820 --> 00:10:15,370 at each intake. 244 00:10:15,370 --> 00:10:21,210 Capable of making thousands of sounds on the way out. 245 00:10:21,210 --> 00:10:24,090 But no matter how pleasant the by product, 246 00:10:24,090 --> 00:10:28,890 there is a higher calling to breathing. 247 00:10:28,890 --> 00:10:31,820 Every breath we take delivers oxygen 248 00:10:31,820 --> 00:10:35,930 to our trillions of power hungry cells 249 00:10:35,930 --> 00:10:37,970 and gets our hearts to pump. 250 00:10:37,970 --> 00:10:38,570 251 00:10:38,570 --> 00:10:40,720 [HEART BEAT] 252 00:10:40,720 --> 00:10:41,705