0:00:00.182,0:00:05.039 So exactly, how does a lack of sleep[br]impact our emotional brain? 0:00:05.063,0:00:06.936 Why does that lack of sleep make us 0:00:06.960,0:00:11.147 so emotionally irrational[br]and hyperreactive? 0:00:11.608,0:00:13.726 [Sleeping with Science] 0:00:16.192,0:00:19.854 Well, several years ago,[br]we conducted a brain imaging study. 0:00:19.878,0:00:22.422 And we took a group of healthy adults. 0:00:22.446,0:00:24.971 And we either gave them[br]a full night of sleep 0:00:24.995,0:00:26.836 or we sleep-deprived them. 0:00:26.860,0:00:30.915 And then the next day,[br]we placed them inside an MRI scanner, 0:00:30.939,0:00:34.568 and we looked at how[br]their emotional brain was reacting. 0:00:34.978,0:00:38.138 And we focused on one[br]structure in particular, 0:00:38.162,0:00:39.859 it's called the amygdala. 0:00:39.883,0:00:43.408 And the amygdala is one[br]of the centerpiece regions 0:00:43.432,0:00:47.479 for the generation[br]of strong emotional reactions, 0:00:47.503,0:00:50.479 including negative emotional reactions. 0:00:50.503,0:00:54.344 Now when we looked at those people[br]who had had a full night of sleep, 0:00:54.368,0:00:59.206 what we saw was a nice,[br]appropriate moderate degree 0:00:59.230,0:01:01.525 of reactivity from the amygdala. 0:01:01.549,0:01:04.356 It wasn't as though[br]there was no response at all, 0:01:04.380,0:01:06.626 but it was an appropriate response. 0:01:06.650,0:01:09.351 Yet in those people[br]who were sleep-deprived, 0:01:09.375,0:01:14.491 that deep emotional brain center[br]was in fact, hyperactive. 0:01:14.515,0:01:19.451 Indeed, the amygdala[br]was almost 60 percent more responsive 0:01:19.475,0:01:22.076 under conditions of a lack of sleep. 0:01:22.100,0:01:24.158 But why was that the case? 0:01:24.570,0:01:26.452 And what we went on to discover, 0:01:26.476,0:01:29.644 is that there's another[br]brain region that's involved. 0:01:30.035,0:01:33.744 This brain region is called[br]the prefrontal cortex, 0:01:33.768,0:01:36.402 and it sits directly above your eyes. 0:01:36.426,0:01:38.712 And you can think[br]of the prefrontal cortex 0:01:38.736,0:01:41.711 almost like the CEO of your brain. 0:01:41.735,0:01:45.489 It's very good at making[br]high-level, executive, top-down 0:01:45.513,0:01:48.475 control decisions and reactions. 0:01:48.910,0:01:52.479 In fact, it's one of the most[br]evolved regions of our brain. 0:01:52.806,0:01:56.381 And one of the parts[br]of the brain that it controls 0:01:56.405,0:01:59.452 is this deep emotional[br]center, the amygdala. 0:01:59.848,0:02:03.095 Now in those people[br]who had had a full night of sleep, 0:02:03.119,0:02:06.419 there was a nice, strong[br]communication and connection 0:02:06.443,0:02:08.348 between the prefrontal cortex, 0:02:08.372,0:02:11.521 regulating that deep[br]emotional brain center. 0:02:11.545,0:02:14.206 But in those people[br]who were sleep-deprived, 0:02:14.230,0:02:18.276 that communication, that connection[br]between the prefrontal cortex 0:02:18.300,0:02:21.371 and that deep amygdala[br]emotional brain center 0:02:21.395,0:02:23.260 had essentially been severed. 0:02:23.284,0:02:24.641 And as a consequence, 0:02:24.665,0:02:28.116 the amygdala was responding[br]far more reactively 0:02:28.140,0:02:29.546 due to a lack of sleep. 0:02:29.570,0:02:31.919 It's almost as though without sleep 0:02:31.943,0:02:35.649 we become all emotional accelerator pedal, 0:02:35.673,0:02:39.217 and too little regulatory control brake. 0:02:39.241,0:02:43.384 And that seems to be the reason[br]that we become so unbuckled 0:02:43.408,0:02:46.289 in terms of our emotional integrity 0:02:46.313,0:02:48.431 when we haven't been sleeping well. 0:02:48.455,0:02:50.601 So that's the bad that can happen 0:02:50.625,0:02:53.401 if I take sleep away from you. 0:02:53.425,0:02:54.770 But it turns out 0:02:54.794,0:02:56.876 that there's something good that happens 0:02:56.900,0:02:59.180 when you get your sleep back. 0:02:59.204,0:03:02.443 And sleep, particularly[br]rapid eye movement sleep, 0:03:02.467,0:03:06.530 actually offers a form[br]of emotional first aid. 0:03:06.887,0:03:09.356 Because it's during sleep at night 0:03:09.380,0:03:12.617 that we take these difficult[br]emotional experiences 0:03:12.641,0:03:14.829 that we've been having during the day, 0:03:14.853,0:03:18.911 and that sleep acts almost[br]like a nocturnal soothing balm, 0:03:18.935,0:03:23.274 taking the sharp edges off[br]those difficult experiences. 0:03:23.605,0:03:28.646 And so perhaps it's not time[br]that heals all wounds, 0:03:28.670,0:03:35.031 it's time during sleep that provides[br]that form of emotional convalescence. 0:03:35.055,0:03:37.183 So that when we come back the next day, 0:03:37.207,0:03:40.160 we're able to cope[br]with those emotional memories.