1 00:00:09,420 --> 00:00:15,580 [Applause] 2 00:00:24,380 --> 00:00:29,699 this looks like a very mild disease like 3 00:00:27,210 --> 00:00:31,949 a common cold in the majority of people 4 00:00:29,699 --> 00:00:34,590 there are certain people who get 5 00:00:31,949 --> 00:00:36,480 infected and have very serious illness 6 00:00:34,590 --> 00:00:38,190 among them are health workers it's a 7 00:00:36,480 --> 00:00:40,290 very serious infection in them as they 8 00:00:38,190 --> 00:00:42,269 get higher dose than normal people and 9 00:00:40,290 --> 00:00:47,070 at the same time they have no immunity 10 00:00:42,269 --> 00:00:49,230 so in in the general population it's 11 00:00:47,070 --> 00:00:51,570 likely that the dose of virus that you 12 00:00:49,230 --> 00:00:53,129 receive when you are infected is much 13 00:00:51,570 --> 00:00:55,470 less than the dose that a health worker 14 00:00:53,129 --> 00:00:57,570 would receive health workers having more 15 00:00:55,470 --> 00:01:00,239 serious infections so your infection 16 00:00:57,570 --> 00:01:01,979 would be less serious hopefully so that 17 00:01:00,239 --> 00:01:04,290 leaves the elderly and those with 18 00:01:01,979 --> 00:01:06,780 comorbidities to really be the ones that 19 00:01:04,290 --> 00:01:09,619 we have to make sure are taken care of 20 00:01:06,780 --> 00:01:09,619 in hospitals 21 00:01:11,530 --> 00:01:17,120 well the most concerned are people who 22 00:01:14,810 --> 00:01:19,370 are first of all in developing countries 23 00:01:17,120 --> 00:01:21,920 and who don't have access to good 24 00:01:19,370 --> 00:01:25,010 medical care and may not have access at 25 00:01:21,920 --> 00:01:27,020 all to a hospital should an epidemic 26 00:01:25,010 --> 00:01:28,580 occur in their country those people 27 00:01:27,020 --> 00:01:31,340 would be a great risk especially the 28 00:01:28,580 --> 00:01:33,590 elderly elderly in all populations are 29 00:01:31,340 --> 00:01:35,870 at risk but especially those who can't 30 00:01:33,590 --> 00:01:38,420 get to oxygen in industrialized 31 00:01:35,870 --> 00:01:40,640 countries it's the very elderly who have 32 00:01:38,420 --> 00:01:42,980 comorbidities who have diabetes who have 33 00:01:40,640 --> 00:01:44,930 other diseases who are at risk the 34 00:01:42,980 --> 00:01:47,530 general population doesn't appear to be 35 00:01:44,930 --> 00:01:47,530 a great risk 36 00:01:49,730 --> 00:01:55,220 first of all pulmonary disease existing 37 00:01:52,790 --> 00:01:57,590 as a comorbidity is also important in 38 00:01:55,220 --> 00:02:00,380 general the elderly are a greater risk 39 00:01:57,590 --> 00:02:03,050 especially those over 70 because their 40 00:02:00,380 --> 00:02:04,880 immune systems are not as effective as 41 00:02:03,050 --> 00:02:07,190 they might have once been and there are 42 00:02:04,880 --> 00:02:10,310 more susceptible to infections in 43 00:02:07,190 --> 00:02:12,560 addition in some instances in China 44 00:02:10,310 --> 00:02:15,320 there's been a CO infection with 45 00:02:12,560 --> 00:02:17,030 influenza and at the same time there 46 00:02:15,320 --> 00:02:18,800 have been some bacterial super 47 00:02:17,030 --> 00:02:21,220 infections on the pneumonias that are 48 00:02:18,800 --> 00:02:21,220 occurring 49 00:02:22,780 --> 00:02:27,130 Center for Disease Control in Atlanta 50 00:02:24,069 --> 00:02:29,980 keeps track and has updates on a regular 51 00:02:27,130 --> 00:02:32,260 basis on its website also the World 52 00:02:29,980 --> 00:02:33,730 Health Organization in Geneva which is 53 00:02:32,260 --> 00:02:36,040 coordinating many of the activities 54 00:02:33,730 --> 00:02:38,290 going on internationally also has a 55 00:02:36,040 --> 00:02:39,970 website with daily updates it's our 56 00:02:38,290 --> 00:02:43,239 responsibility to get that information 57 00:02:39,970 --> 00:02:44,860 as individuals so we understand and can 58 00:02:43,239 --> 00:02:49,380 make sure that we can contribute in our 59 00:02:44,860 --> 00:02:49,380 own way to prevention of major spread 60 00:02:51,990 --> 00:02:55,740 that's the same problem with all new 61 00:02:53,910 --> 00:02:57,990 infections this is an infection that's 62 00:02:55,740 --> 00:03:00,690 coming to humans who have never been 63 00:02:57,990 --> 00:03:03,420 exposed to this virus before they don't 64 00:03:00,690 --> 00:03:05,310 have any antibody protection and it's 65 00:03:03,420 --> 00:03:07,620 not clear whether their immune system 66 00:03:05,310 --> 00:03:10,380 can handle this virus or not this is a 67 00:03:07,620 --> 00:03:12,510 virus that usually finds itself in bats 68 00:03:10,380 --> 00:03:15,180 or in other animals and all of a sudden 69 00:03:12,510 --> 00:03:17,100 it's in humans and humans just don't 70 00:03:15,180 --> 00:03:18,660 have experience with this virus but 71 00:03:17,100 --> 00:03:21,630 gradually we are beginning to learn a 72 00:03:18,660 --> 00:03:24,210 lot as we did with SARS and you know 73 00:03:21,630 --> 00:03:26,970 there are certainly a larger number of 74 00:03:24,210 --> 00:03:29,340 deaths than there were with SARS but 75 00:03:26,970 --> 00:03:31,380 when you divide that by a denominator of 76 00:03:29,340 --> 00:03:33,150 persons who are infected there are many 77 00:03:31,380 --> 00:03:35,820 many more persons infected than that 78 00:03:33,150 --> 00:03:38,730 where with SARS the case fatality ratio 79 00:03:35,820 --> 00:03:41,310 that is the ratio of deaths to the 80 00:03:38,730 --> 00:03:44,010 numbers of cases in SARS was about 10 81 00:03:41,310 --> 00:03:48,990 percent with the current coronavirus 82 00:03:44,010 --> 00:03:51,480 Koba 19 is 2 percent or probably less so 83 00:03:48,990 --> 00:03:53,520 it's a much less virulent virus but it's 84 00:03:51,480 --> 00:03:54,930 still a virus that causes mortality and 85 00:03:53,520 --> 00:03:58,280 that's what we don't want 86 00:03:54,930 --> 00:03:58,280 entering human populations 87 00:04:00,040 --> 00:04:05,620 it's clearly understood that airports or 88 00:04:03,340 --> 00:04:07,750 any land borders cannot prevent the 89 00:04:05,620 --> 00:04:09,579 disease from entering people in the 90 00:04:07,750 --> 00:04:12,400 incubation period can cross that border 91 00:04:09,579 --> 00:04:14,950 can enter countries and can then infect 92 00:04:12,400 --> 00:04:18,269 others when they become sick so its 93 00:04:14,950 --> 00:04:20,500 borders are not a means of preventing 94 00:04:18,269 --> 00:04:22,900 infections from entering a country by 95 00:04:20,500 --> 00:04:24,850 checking temperatures borders are 96 00:04:22,900 --> 00:04:27,370 important because you can provide to 97 00:04:24,850 --> 00:04:29,259 people arriving from areas that might be 98 00:04:27,370 --> 00:04:31,389 at risk of having had infection 99 00:04:29,259 --> 00:04:33,430 providing them with an understanding 100 00:04:31,389 --> 00:04:35,740 either a printed understanding or a 101 00:04:33,430 --> 00:04:37,599 verbal understanding of what the signs 102 00:04:35,740 --> 00:04:40,300 and symptoms are of this infection and 103 00:04:37,599 --> 00:04:43,440 what they should do if they feel that 104 00:04:40,300 --> 00:04:43,440 they might be infected 105 00:04:44,500 --> 00:04:48,700 vaccines are under development right now 106 00:04:46,720 --> 00:04:51,490 there's a lot of research going on that 107 00:04:48,700 --> 00:04:54,250 research requires first that the vaccine 108 00:04:51,490 --> 00:04:57,460 be developed then that it be studied for 109 00:04:54,250 --> 00:04:59,110 safety and effectiveness in animals who 110 00:04:57,460 --> 00:05:00,670 are challenged with the virus when 111 00:04:59,110 --> 00:05:03,370 they're after they're in vaccinated and 112 00:05:00,670 --> 00:05:05,560 then it was going to human studies the 113 00:05:03,370 --> 00:05:07,630 animal studies have not yet begun but 114 00:05:05,560 --> 00:05:10,000 will soon begin for certain vaccines and 115 00:05:07,630 --> 00:05:11,770 it's thought that by the end of the year 116 00:05:10,000 --> 00:05:14,380 or early next year there may be some 117 00:05:11,770 --> 00:05:17,410 candidate vaccines that can then be 118 00:05:14,380 --> 00:05:20,320 studied for licensing by regulatory 119 00:05:17,410 --> 00:05:22,480 agencies so we're talking about at least 120 00:05:20,320 --> 00:05:26,550 a year until there's vaccine available 121 00:05:22,480 --> 00:05:26,550 that can be used in many populations 122 00:05:28,990 --> 00:05:33,310 that's clear we know how it transmits we 123 00:05:31,180 --> 00:05:37,229 don't know how easily it transmits in 124 00:05:33,310 --> 00:05:40,330 humans in communities or in unenclosed 125 00:05:37,229 --> 00:05:42,130 areas we know and for example they did 126 00:05:40,330 --> 00:05:44,530 in the enclosed area of a cruise ship it 127 00:05:42,130 --> 00:05:46,660 spread very easily we need to better 128 00:05:44,530 --> 00:05:49,389 understand how it will spread once it 129 00:05:46,660 --> 00:05:54,090 gets into more open areas where people 130 00:05:49,389 --> 00:05:54,090 are exposed to people who might be sick 131 00:05:56,310 --> 00:06:00,960 a major problem in the world today is 132 00:05:58,380 --> 00:06:02,940 that we look at outbreaks in developing 133 00:06:00,960 --> 00:06:05,520 countries there's something that we need 134 00:06:02,940 --> 00:06:07,560 to go and stop so when there's an 135 00:06:05,520 --> 00:06:09,900 outbreak of Ebola we think how can we go 136 00:06:07,560 --> 00:06:12,710 and stop this outbreak because we don't 137 00:06:09,900 --> 00:06:15,750 think about how can we help that country 138 00:06:12,710 --> 00:06:19,050 strengthen its capacity so that it can 139 00:06:15,750 --> 00:06:21,930 detect and respond to infections so we 140 00:06:19,050 --> 00:06:24,330 haven't invested enough in helping 141 00:06:21,930 --> 00:06:26,100 countries develop their core capacity in 142 00:06:24,330 --> 00:06:28,770 public health what we've done is 143 00:06:26,100 --> 00:06:31,650 invested in many mechanisms globally 144 00:06:28,770 --> 00:06:33,840 which can provide support to other 145 00:06:31,650 --> 00:06:35,910 countries to go and help stop outbreaks 146 00:06:33,840 --> 00:06:38,100 but we want to see a world where every 147 00:06:35,910 --> 00:06:40,610 country can do its best to stop its own 148 00:06:38,100 --> 00:06:40,610 outbreaks 149 00:06:41,690 --> 00:06:45,440 today there are over seven billion 150 00:06:43,310 --> 00:06:47,000 people and when those people come into 151 00:06:45,440 --> 00:06:48,920 the world they demand more food they 152 00:06:47,000 --> 00:06:50,030 demand a whole series of things and they 153 00:06:48,920 --> 00:06:51,950 live closer together 154 00:06:50,030 --> 00:06:54,590 in fact we're in an urban world where 155 00:06:51,950 --> 00:06:56,960 people live in urban areas and at the 156 00:06:54,590 --> 00:06:59,810 same time we're growing more animals and 157 00:06:56,960 --> 00:07:02,960 those animals are contributing food to 158 00:06:59,810 --> 00:07:05,300 humans as well so what we see is that 159 00:07:02,960 --> 00:07:08,900 that animal human interface is becoming 160 00:07:05,300 --> 00:07:11,480 closer and closer together and and this 161 00:07:08,900 --> 00:07:13,820 intensive agriculture of animals and 162 00:07:11,480 --> 00:07:15,620 this intensive increase in human 163 00:07:13,820 --> 00:07:19,190 populations living together on the same 164 00:07:15,620 --> 00:07:22,130 planet is really a melting pot where 165 00:07:19,190 --> 00:07:23,960 outbreaks can occur and do occur we will 166 00:07:22,130 --> 00:07:27,860 eventually have more and more of these 167 00:07:23,960 --> 00:07:29,690 outbreaks so an emerging infection today 168 00:07:27,860 --> 00:07:31,580 is just a warning of what will happen in 169 00:07:29,690 --> 00:07:33,890 the future we have to make sure that 170 00:07:31,580 --> 00:07:37,250 that technical collaboration in the 171 00:07:33,890 --> 00:07:38,750 world is there to work together to make 172 00:07:37,250 --> 00:07:40,880 sure that we can understand these 173 00:07:38,750 --> 00:07:42,890 outbreaks when they occur and rapidly 174 00:07:40,880 --> 00:07:45,460 provide the information necessary to 175 00:07:42,890 --> 00:07:45,460 control 176 00:07:46,260 --> 00:07:50,310 I can't predict with accuracy so all I 177 00:07:48,450 --> 00:07:53,700 can say is that we must all be prepared 178 00:07:50,310 --> 00:07:55,800 for the worst-case scenario and at the 179 00:07:53,700 --> 00:07:58,110 same time learn how we can protect 180 00:07:55,800 --> 00:08:01,640 ourselves and protect others should we 181 00:07:58,110 --> 00:08:01,640 become a part of that a together 182 00:08:05,050 --> 00:08:08,569 [Music] 183 00:08:09,320 --> 00:08:11,380 you