0:00:09.420,0:00:15.580 [Applause] 0:00:24.380,0:00:29.699 this looks like a very mild disease like 0:00:27.210,0:00:31.949 a common cold in the majority of people 0:00:29.699,0:00:34.590 there are certain people who get 0:00:31.949,0:00:36.480 infected and have very serious illness 0:00:34.590,0:00:38.190 among them are health workers it's a 0:00:36.480,0:00:40.290 very serious infection in them as they 0:00:38.190,0:00:42.269 get higher dose than normal people and 0:00:40.290,0:00:47.070 at the same time they have no immunity 0:00:42.269,0:00:49.230 so in in the general population it's 0:00:47.070,0:00:51.570 likely that the dose of virus that you 0:00:49.230,0:00:53.129 receive when you are infected is much 0:00:51.570,0:00:55.470 less than the dose that a health worker 0:00:53.129,0:00:57.570 would receive health workers having more 0:00:55.470,0:01:00.239 serious infections so your infection 0:00:57.570,0:01:01.979 would be less serious hopefully so that 0:01:00.239,0:01:04.290 leaves the elderly and those with 0:01:01.979,0:01:06.780 comorbidities to really be the ones that 0:01:04.290,0:01:09.619 we have to make sure are taken care of 0:01:06.780,0:01:09.619 in hospitals 0:01:11.530,0:01:17.120 well the most concerned are people who 0:01:14.810,0:01:19.370 are first of all in developing countries 0:01:17.120,0:01:21.920 and who don't have access to good 0:01:19.370,0:01:25.010 medical care and may not have access at 0:01:21.920,0:01:27.020 all to a hospital should an epidemic 0:01:25.010,0:01:28.580 occur in their country those people 0:01:27.020,0:01:31.340 would be a great risk especially the 0:01:28.580,0:01:33.590 elderly elderly in all populations are 0:01:31.340,0:01:35.870 at risk but especially those who can't 0:01:33.590,0:01:38.420 get to oxygen in industrialized 0:01:35.870,0:01:40.640 countries it's the very elderly who have 0:01:38.420,0:01:42.980 comorbidities who have diabetes who have 0:01:40.640,0:01:44.930 other diseases who are at risk the 0:01:42.980,0:01:47.530 general population doesn't appear to be 0:01:44.930,0:01:47.530 a great risk 0:01:49.730,0:01:55.220 first of all pulmonary disease existing 0:01:52.790,0:01:57.590 as a comorbidity is also important in 0:01:55.220,0:02:00.380 general the elderly are a greater risk 0:01:57.590,0:02:03.050 especially those over 70 because their 0:02:00.380,0:02:04.880 immune systems are not as effective as 0:02:03.050,0:02:07.190 they might have once been and there are 0:02:04.880,0:02:10.310 more susceptible to infections in 0:02:07.190,0:02:12.560 addition in some instances in China 0:02:10.310,0:02:15.320 there's been a CO infection with 0:02:12.560,0:02:17.030 influenza and at the same time there 0:02:15.320,0:02:18.800 have been some bacterial super 0:02:17.030,0:02:21.220 infections on the pneumonias that are 0:02:18.800,0:02:21.220 occurring 0:02:22.780,0:02:27.130 Center for Disease Control in Atlanta 0:02:24.069,0:02:29.980 keeps track and has updates on a regular 0:02:27.130,0:02:32.260 basis on its website also the World 0:02:29.980,0:02:33.730 Health Organization in Geneva which is 0:02:32.260,0:02:36.040 coordinating many of the activities 0:02:33.730,0:02:38.290 going on internationally also has a 0:02:36.040,0:02:39.970 website with daily updates it's our 0:02:38.290,0:02:43.239 responsibility to get that information 0:02:39.970,0:02:44.860 as individuals so we understand and can 0:02:43.239,0:02:49.380 make sure that we can contribute in our 0:02:44.860,0:02:49.380 own way to prevention of major spread 0:02:51.990,0:02:55.740 that's the same problem with all new 0:02:53.910,0:02:57.990 infections this is an infection that's 0:02:55.740,0:03:00.690 coming to humans who have never been 0:02:57.990,0:03:03.420 exposed to this virus before they don't 0:03:00.690,0:03:05.310 have any antibody protection and it's 0:03:03.420,0:03:07.620 not clear whether their immune system 0:03:05.310,0:03:10.380 can handle this virus or not this is a 0:03:07.620,0:03:12.510 virus that usually finds itself in bats 0:03:10.380,0:03:15.180 or in other animals and all of a sudden 0:03:12.510,0:03:17.100 it's in humans and humans just don't 0:03:15.180,0:03:18.660 have experience with this virus but 0:03:17.100,0:03:21.630 gradually we are beginning to learn a 0:03:18.660,0:03:24.210 lot as we did with SARS and you know 0:03:21.630,0:03:26.970 there are certainly a larger number of 0:03:24.210,0:03:29.340 deaths than there were with SARS but 0:03:26.970,0:03:31.380 when you divide that by a denominator of 0:03:29.340,0:03:33.150 persons who are infected there are many 0:03:31.380,0:03:35.820 many more persons infected than that 0:03:33.150,0:03:38.730 where with SARS the case fatality ratio 0:03:35.820,0:03:41.310 that is the ratio of deaths to the 0:03:38.730,0:03:44.010 numbers of cases in SARS was about 10 0:03:41.310,0:03:48.990 percent with the current coronavirus 0:03:44.010,0:03:51.480 Koba 19 is 2 percent or probably less so 0:03:48.990,0:03:53.520 it's a much less virulent virus but it's 0:03:51.480,0:03:54.930 still a virus that causes mortality and 0:03:53.520,0:03:58.280 that's what we don't want 0:03:54.930,0:03:58.280 entering human populations 0:04:00.040,0:04:05.620 it's clearly understood that airports or 0:04:03.340,0:04:07.750 any land borders cannot prevent the 0:04:05.620,0:04:09.579 disease from entering people in the 0:04:07.750,0:04:12.400 incubation period can cross that border 0:04:09.579,0:04:14.950 can enter countries and can then infect 0:04:12.400,0:04:18.269 others when they become sick so its 0:04:14.950,0:04:20.500 borders are not a means of preventing 0:04:18.269,0:04:22.900 infections from entering a country by 0:04:20.500,0:04:24.850 checking temperatures borders are 0:04:22.900,0:04:27.370 important because you can provide to 0:04:24.850,0:04:29.259 people arriving from areas that might be 0:04:27.370,0:04:31.389 at risk of having had infection 0:04:29.259,0:04:33.430 providing them with an understanding 0:04:31.389,0:04:35.740 either a printed understanding or a 0:04:33.430,0:04:37.599 verbal understanding of what the signs 0:04:35.740,0:04:40.300 and symptoms are of this infection and 0:04:37.599,0:04:43.440 what they should do if they feel that 0:04:40.300,0:04:43.440 they might be infected 0:04:44.500,0:04:48.700 vaccines are under development right now 0:04:46.720,0:04:51.490 there's a lot of research going on that 0:04:48.700,0:04:54.250 research requires first that the vaccine 0:04:51.490,0:04:57.460 be developed then that it be studied for 0:04:54.250,0:04:59.110 safety and effectiveness in animals who 0:04:57.460,0:05:00.670 are challenged with the virus when 0:04:59.110,0:05:03.370 they're after they're in vaccinated and 0:05:00.670,0:05:05.560 then it was going to human studies the 0:05:03.370,0:05:07.630 animal studies have not yet begun but 0:05:05.560,0:05:10.000 will soon begin for certain vaccines and 0:05:07.630,0:05:11.770 it's thought that by the end of the year 0:05:10.000,0:05:14.380 or early next year there may be some 0:05:11.770,0:05:17.410 candidate vaccines that can then be 0:05:14.380,0:05:20.320 studied for licensing by regulatory 0:05:17.410,0:05:22.480 agencies so we're talking about at least 0:05:20.320,0:05:26.550 a year until there's vaccine available 0:05:22.480,0:05:26.550 that can be used in many populations 0:05:28.990,0:05:33.310 that's clear we know how it transmits we 0:05:31.180,0:05:37.229 don't know how easily it transmits in 0:05:33.310,0:05:40.330 humans in communities or in unenclosed 0:05:37.229,0:05:42.130 areas we know and for example they did 0:05:40.330,0:05:44.530 in the enclosed area of a cruise ship it 0:05:42.130,0:05:46.660 spread very easily we need to better 0:05:44.530,0:05:49.389 understand how it will spread once it 0:05:46.660,0:05:54.090 gets into more open areas where people 0:05:49.389,0:05:54.090 are exposed to people who might be sick 0:05:56.310,0:06:00.960 a major problem in the world today is 0:05:58.380,0:06:02.940 that we look at outbreaks in developing 0:06:00.960,0:06:05.520 countries there's something that we need 0:06:02.940,0:06:07.560 to go and stop so when there's an 0:06:05.520,0:06:09.900 outbreak of Ebola we think how can we go 0:06:07.560,0:06:12.710 and stop this outbreak because we don't 0:06:09.900,0:06:15.750 think about how can we help that country 0:06:12.710,0:06:19.050 strengthen its capacity so that it can 0:06:15.750,0:06:21.930 detect and respond to infections so we 0:06:19.050,0:06:24.330 haven't invested enough in helping 0:06:21.930,0:06:26.100 countries develop their core capacity in 0:06:24.330,0:06:28.770 public health what we've done is 0:06:26.100,0:06:31.650 invested in many mechanisms globally 0:06:28.770,0:06:33.840 which can provide support to other 0:06:31.650,0:06:35.910 countries to go and help stop outbreaks 0:06:33.840,0:06:38.100 but we want to see a world where every 0:06:35.910,0:06:40.610 country can do its best to stop its own 0:06:38.100,0:06:40.610 outbreaks 0:06:41.690,0:06:45.440 today there are over seven billion 0:06:43.310,0:06:47.000 people and when those people come into 0:06:45.440,0:06:48.920 the world they demand more food they 0:06:47.000,0:06:50.030 demand a whole series of things and they 0:06:48.920,0:06:51.950 live closer together 0:06:50.030,0:06:54.590 in fact we're in an urban world where 0:06:51.950,0:06:56.960 people live in urban areas and at the 0:06:54.590,0:06:59.810 same time we're growing more animals and 0:06:56.960,0:07:02.960 those animals are contributing food to 0:06:59.810,0:07:05.300 humans as well so what we see is that 0:07:02.960,0:07:08.900 that animal human interface is becoming 0:07:05.300,0:07:11.480 closer and closer together and and this 0:07:08.900,0:07:13.820 intensive agriculture of animals and 0:07:11.480,0:07:15.620 this intensive increase in human 0:07:13.820,0:07:19.190 populations living together on the same 0:07:15.620,0:07:22.130 planet is really a melting pot where 0:07:19.190,0:07:23.960 outbreaks can occur and do occur we will 0:07:22.130,0:07:27.860 eventually have more and more of these 0:07:23.960,0:07:29.690 outbreaks so an emerging infection today 0:07:27.860,0:07:31.580 is just a warning of what will happen in 0:07:29.690,0:07:33.890 the future we have to make sure that 0:07:31.580,0:07:37.250 that technical collaboration in the 0:07:33.890,0:07:38.750 world is there to work together to make 0:07:37.250,0:07:40.880 sure that we can understand these 0:07:38.750,0:07:42.890 outbreaks when they occur and rapidly 0:07:40.880,0:07:45.460 provide the information necessary to 0:07:42.890,0:07:45.460 control 0:07:46.260,0:07:50.310 I can't predict with accuracy so all I 0:07:48.450,0:07:53.700 can say is that we must all be prepared 0:07:50.310,0:07:55.800 for the worst-case scenario and at the 0:07:53.700,0:07:58.110 same time learn how we can protect 0:07:55.800,0:08:01.640 ourselves and protect others should we 0:07:58.110,0:08:01.640 become a part of that a together 0:08:05.050,0:08:08.569 [Music] 0:08:09.320,0:08:11.380 you