1 00:00:00,771 --> 00:00:04,135 What's the fastest growing threat to Americans' health? 2 00:00:04,135 --> 00:00:06,973 Cancer? Heart attacks? Diabetes? 3 00:00:07,603 --> 00:00:09,449 The answer is actually none of these; 4 00:00:09,449 --> 00:00:11,250 it's Alzheimer's disease. 5 00:00:11,250 --> 00:00:13,276 Every 67 seconds, 6 00:00:13,276 --> 00:00:16,221 someone in the United States is diagnosed with Alzheimer's. 7 00:00:16,761 --> 00:00:20,149 As the number of Alzheimer's patients triples by the year 2050, 8 00:00:20,149 --> 00:00:23,446 caring for them, as well as the rest of the aging population, 9 00:00:23,446 --> 00:00:26,005 will become an overwhelming societal challenge. 10 00:00:26,585 --> 00:00:28,465 My family has experienced firsthand 11 00:00:28,465 --> 00:00:30,967 the struggles of caring for an Alzheimer's patient. 12 00:00:30,967 --> 00:00:33,107 Growing up in a family with three generations, 13 00:00:33,107 --> 00:00:35,262 I've always been very close to my grandfather. 14 00:00:35,262 --> 00:00:36,689 When I was four years old, 15 00:00:36,689 --> 00:00:39,192 my grandfather and I were walking in a park in Japan 16 00:00:39,192 --> 00:00:40,497 when he suddenly got lost. 17 00:00:40,497 --> 00:00:43,710 It was one of the scariest moments I've ever experienced in my life, 18 00:00:43,710 --> 00:00:46,117 and it was also the first instance that informed us 19 00:00:46,117 --> 00:00:48,412 that my grandfather had Alzheimer's disease. 20 00:00:48,682 --> 00:00:52,025 Over the past 12 years, his condition got worse and worse, 21 00:00:52,025 --> 00:00:55,823 and his wandering in particular caused my family a lot of stress. 22 00:00:55,823 --> 00:00:57,302 My aunt, his primary caregiver, 23 00:00:57,302 --> 00:01:00,349 really struggled to stay awake at night to keep an eye on him, 24 00:01:00,349 --> 00:01:03,047 and even then often failed to catch him leaving the bed. 25 00:01:03,047 --> 00:01:05,858 I became really concerned about my aunt's well-being 26 00:01:05,858 --> 00:01:07,599 as well as my grandfather's safety. 27 00:01:07,599 --> 00:01:11,130 I searched extensively for a solution that could help my family's problems, 28 00:01:11,130 --> 00:01:12,490 but couldn't find one. 29 00:01:12,960 --> 00:01:15,693 Then, one night about two years ago, 30 00:01:15,693 --> 00:01:19,158 I was looking after my grandfather and I saw him stepping out of the bed. 31 00:01:19,158 --> 00:01:21,150 The moment his foot landed on the floor, 32 00:01:21,150 --> 00:01:24,412 I thought, why don't I put a pressure sensor on the heel of his foot? 33 00:01:24,412 --> 00:01:26,809 Once he stepped onto the floor and out of the bed, 34 00:01:26,809 --> 00:01:30,516 the pressure sensor would detect an increase in pressure caused by body weight 35 00:01:30,516 --> 00:01:33,971 and then wirelessly send an audible alert to the caregiver's smartphone. 36 00:01:33,971 --> 00:01:36,312 That way, my aunt could sleep much better at night 37 00:01:36,312 --> 00:01:39,002 without having to worry about my grandfather's wandering. 38 00:01:39,002 --> 00:01:42,934 So now I'd like to perform a demonstration of this sock. 39 00:01:45,134 --> 00:01:47,802 Could I please have my sock model on the stage? 40 00:01:48,831 --> 00:01:50,560 Great. 41 00:01:52,170 --> 00:01:55,950 So once the patient steps onto the floor -- 42 00:01:55,950 --> 00:01:57,510 (Ringing) -- 43 00:01:57,510 --> 00:02:00,182 an alert is sent to the caregiver's smartphone. 44 00:02:04,571 --> 00:02:06,057 Thank you. (Applause) 45 00:02:06,057 --> 00:02:09,225 Thank you, sock model. 46 00:02:12,045 --> 00:02:14,649 So this is a drawing of my preliminary design. 47 00:02:15,819 --> 00:02:18,441 My desire to create a sensor-based technology 48 00:02:18,441 --> 00:02:21,969 perhaps stemmed from my lifelong love for sensors and technology. 49 00:02:21,979 --> 00:02:23,465 When I was six years old, 50 00:02:23,465 --> 00:02:25,795 an elderly family friend fell down in the bathroom 51 00:02:25,795 --> 00:02:27,505 and suffered severe injuries. 52 00:02:27,505 --> 00:02:29,606 I became concerned about my own grandparents 53 00:02:29,606 --> 00:02:31,958 and decided to invent a smart bathroom system. 54 00:02:31,958 --> 00:02:35,566 Motion sensors would be installed inside the tiles of bathroom floors 55 00:02:35,566 --> 00:02:39,404 to detect the falls of elderly patients whenever they fell down in the bathroom. 56 00:02:39,404 --> 00:02:41,416 Since I was only six years old at the time 57 00:02:41,416 --> 00:02:43,739 and I hadn't graduated from kindergarten yet, 58 00:02:43,739 --> 00:02:48,073 I didn't have the necessary resources and tools to translate my idea into reality, 59 00:02:48,073 --> 00:02:50,706 but nonetheless, my research experience 60 00:02:50,706 --> 00:02:54,957 really implanted in me a firm desire to use sensors to help the elderly people. 61 00:02:54,957 --> 00:02:59,573 I really believe that sensors can improve the quality of life of the elderly. 62 00:03:00,944 --> 00:03:04,425 When I laid out my plan, I realized that I faced three main challenges: 63 00:03:04,425 --> 00:03:06,194 first, creating a sensor; 64 00:03:06,194 --> 00:03:07,773 second, designing a circuit; 65 00:03:07,773 --> 00:03:09,519 and third, coding a smartphone app. 66 00:03:09,519 --> 00:03:12,927 This made me realize that my project was actually much harder to realize 67 00:03:12,927 --> 00:03:14,982 than I initially had thought it to be. 68 00:03:14,982 --> 00:03:18,476 First, I had to create a wearable sensor that was thin and flexible enough 69 00:03:18,476 --> 00:03:21,237 to be worn comfortably on the bottom of the patient's foot. 70 00:03:21,237 --> 00:03:24,656 After extensive research and testing of different materials like rubber, 71 00:03:24,656 --> 00:03:28,191 which I realized was too thick to be worn snugly on the bottom of the foot, 72 00:03:28,191 --> 00:03:29,758 I decided to print a film sensor 73 00:03:29,758 --> 00:03:32,660 with electrically conductive pressure-sensitive ink particles. 74 00:03:32,660 --> 00:03:36,236 Once pressure is applied, the connectivity between the particles increases. 75 00:03:36,236 --> 00:03:39,200 Therefore, I could design a circuit that would measure pressure 76 00:03:39,200 --> 00:03:40,967 by measuring electrical resistance. 77 00:03:41,267 --> 00:03:44,026 Next, I had to design a wearable wireless circuit, 78 00:03:44,026 --> 00:03:47,338 but wireless signal transmission consumes lots of power 79 00:03:47,338 --> 00:03:49,101 and requires heavy, bulky batteries. 80 00:03:49,101 --> 00:03:52,728 Thankfully, I was able to find out about the Bluetooth low energy technology, 81 00:03:52,728 --> 00:03:56,251 which consumes very little power and can be driven by a coin-sized battery. 82 00:03:56,251 --> 00:03:59,880 This prevented the system from dying in the middle of the night. 83 00:03:59,880 --> 00:04:03,343 Lastly, I had to code a smartphone app that would essentially transform 84 00:04:03,343 --> 00:04:05,821 the care-giver's smartphone into a remote monitor. 85 00:04:05,821 --> 00:04:09,497 For this, I had to expand upon my knowledge of coding with Java and XCode 86 00:04:09,497 --> 00:04:12,984 and I also had to learn about how to code for Bluetooth low energy devices 87 00:04:12,984 --> 00:04:15,860 by watching YouTube tutorials and reading various textbooks. 88 00:04:17,230 --> 00:04:21,019 Integrating these components, I was able to successfully create two prototypes, 89 00:04:21,019 --> 00:04:23,347 one in which the sensor is embedded inside a sock, 90 00:04:23,347 --> 00:04:25,743 and another that's a re-attachable sensor assembly 91 00:04:25,743 --> 00:04:27,949 that can be adhered anywhere that makes contact 92 00:04:27,949 --> 00:04:29,782 with the bottom of the patient's foot. 93 00:04:29,782 --> 00:04:32,682 I've tested the device on my grandfather for about a year now, 94 00:04:32,682 --> 00:04:34,593 and it's had a 100 percent success rate 95 00:04:34,593 --> 00:04:38,089 in detecting the over 900 known cases of his wandering. 96 00:04:38,629 --> 00:04:41,052 Last summer, I was able to beta test my device 97 00:04:41,052 --> 00:04:43,598 at several residential care facilities in California, 98 00:04:43,598 --> 00:04:45,770 and I'm currently incorporating the feedback 99 00:04:45,770 --> 00:04:48,733 to further improve the device into a marketable product. 100 00:04:48,733 --> 00:04:50,841 Testing the device on a number of patients 101 00:04:50,841 --> 00:04:53,350 made me realize that I needed to invent solutions 102 00:04:53,350 --> 00:04:56,235 for people who didn't want to wear socks to sleep at night. 103 00:04:56,805 --> 00:04:59,630 So sensor data, collected on a vast number of patients, 104 00:04:59,630 --> 00:05:01,959 can be useful for improving patient care 105 00:05:01,959 --> 00:05:04,777 and also leading to a cure for the disease, possibly. 106 00:05:04,777 --> 00:05:06,620 For example, I'm currently examining 107 00:05:06,620 --> 00:05:09,848 correlations between the frequency of a patient's nightly wandering 108 00:05:09,848 --> 00:05:12,714 and his or her daily activities and diet. 109 00:05:13,854 --> 00:05:16,615 One thing I'll never forget is when my device first caught 110 00:05:16,615 --> 00:05:18,833 my grandfather's wandering out of bed at night. 111 00:05:18,833 --> 00:05:21,784 At that moment, I was really struck by the power of technology 112 00:05:21,784 --> 00:05:23,761 to change lives for the better. 113 00:05:24,011 --> 00:05:26,131 People living happily and healthfully -- 114 00:05:26,131 --> 00:05:28,156 that's the world that I imagine. 115 00:05:28,156 --> 00:05:30,216 Thank you very much. 116 00:05:30,216 --> 00:05:33,526 (Applause)