WEBVTT 00:00:00.771 --> 00:00:04.135 What's the fastest growing threat to Americans' health? 00:00:04.135 --> 00:00:06.973 Cancer? Heart attacks? Diabetes? 00:00:07.603 --> 00:00:09.449 The answer is actually none of these: 00:00:09.449 --> 00:00:11.250 it's Alzheimer's disease. 00:00:11.250 --> 00:00:13.276 Every 67 seconds, 00:00:13.276 --> 00:00:16.921 someone in the United States is diagnosed with Alzheimer's. 00:00:16.921 --> 00:00:20.149 As the number of Alzheimer's patients triples by the year 2050, 00:00:20.149 --> 00:00:23.446 caring for them, as well as the rest of the aging population, 00:00:23.446 --> 00:00:26.005 will become an overwhelming society challenge. NOTE Paragraph 00:00:26.585 --> 00:00:28.465 My family has experienced firsthand 00:00:28.465 --> 00:00:30.967 the struggles of caring for an Alzheimer's patient. 00:00:30.967 --> 00:00:33.107 Growing up in a family with three generations, 00:00:33.107 --> 00:00:35.262 I've always been very close to my grandfather. 00:00:35.262 --> 00:00:36.689 When I was four years old, 00:00:36.689 --> 00:00:39.192 my grandfather and I were walking in a park in Japan 00:00:39.192 --> 00:00:40.497 when he suddenly got lost. 00:00:40.497 --> 00:00:43.730 It was one of the scariest moments I've ever experienced in my life, 00:00:43.730 --> 00:00:47.167 and it was also the first instance that informed us that my grandfather 00:00:47.167 --> 00:00:48.412 had Alzheimer's disease. 00:00:48.942 --> 00:00:52.025 Over the past 12 years, his condition got worse and worse, 00:00:52.025 --> 00:00:55.823 and his wandering in particular caused my family a lot of stress. 00:00:55.823 --> 00:00:57.302 My aunt, his primary caregiver, 00:00:57.302 --> 00:01:00.349 really struggled to stay awake at night to keep an eye on him, 00:01:00.349 --> 00:01:03.047 and even then often failed to catch him leaving the bed. 00:01:03.047 --> 00:01:05.858 I became really concerned about my aunt's well-being 00:01:05.858 --> 00:01:07.599 as well as my grandfather's safety. 00:01:07.599 --> 00:01:11.150 I searched extensively for a solution that could help my family's problems, 00:01:11.150 --> 00:01:12.450 but couldn't find one. NOTE Paragraph 00:01:12.960 --> 00:01:15.693 Then, one night about two years ago, 00:01:15.693 --> 00:01:19.158 I was looking after my grandfather and I saw him stepping out of the bed. 00:01:19.158 --> 00:01:21.150 The moment his foot landed on the floor, 00:01:21.150 --> 00:01:24.412 I thought, why don't I put a pressure sensor on the heel of his foot? 00:01:24.412 --> 00:01:26.809 Once he stepped onto the floor and out of the bed, 00:01:26.809 --> 00:01:30.516 the pressure sensor would detect an increase in pressure caused by body weight 00:01:30.516 --> 00:01:33.971 and then wirelessly send an audible alert to the caregiver's smart phone. 00:01:33.971 --> 00:01:36.312 That way, my aunt could sleep much better at night 00:01:36.312 --> 00:01:39.002 without having to worry about my grandfather's wandering. NOTE Paragraph 00:01:39.002 --> 00:01:42.934 So now I'd like to perform a demonstration of this sock. 00:01:45.134 --> 00:01:47.802 Could I please have my sock model on the stage? 00:01:48.831 --> 00:01:50.560 Great. 00:01:52.590 --> 00:01:56.727 So once the patient steps onto the floor, 00:01:57.567 --> 00:02:00.182 an alert is sent to the caregiver's smartphone. NOTE Paragraph 00:02:04.571 --> 00:02:06.057 Thank you. (Applause) NOTE Paragraph 00:02:06.057 --> 00:02:09.225 Thank you sock model. NOTE Paragraph 00:02:12.045 --> 00:02:14.489 So this is a drawing of my preliminary design. NOTE Paragraph 00:02:15.819 --> 00:02:18.441 My desire to create a sensor-based technology 00:02:18.441 --> 00:02:21.969 perhaps stemmed from my life-long love for sensors and technology. 00:02:22.449 --> 00:02:24.925 When I was six years old, an elderly family friend 00:02:24.925 --> 00:02:27.498 fell down in the bathroom and suffered severe injuries. 00:02:27.498 --> 00:02:29.606 I became concerned about my own grandparents 00:02:29.606 --> 00:02:32.108 and decided to invent a smart bathroom system. 00:02:32.108 --> 00:02:35.566 Motion sensors would be installed inside the tiles of bathroom floors 00:02:35.566 --> 00:02:39.404 to detect the falls of elderly patients whenever they fell down in the bathroom. 00:02:39.404 --> 00:02:41.416 Since I was only six years old at the time 00:02:41.416 --> 00:02:43.739 and I hadn't graduated from kindergarten yet, 00:02:43.739 --> 00:02:48.073 I didn't have the necessary resources and tools to translate my idea into reality, 00:02:48.073 --> 00:02:50.706 but nonetheless, my research experience 00:02:50.706 --> 00:02:54.957 really implanted in my a firm desire to use sensors to help the elderly people. 00:02:54.957 --> 00:02:58.003 I really believed that sensors could improve the quality of life 00:02:58.003 --> 00:02:59.694 of the elderly. NOTE Paragraph 00:03:01.254 --> 00:03:04.675 When I laid out my plan, I realized that I faced three main challenges: 00:03:04.675 --> 00:03:06.194 first, creating a sensor; 00:03:06.194 --> 00:03:07.773 second, designing a circuit; 00:03:07.773 --> 00:03:09.519 and third, coding a smartphone app. 00:03:09.519 --> 00:03:12.927 This made me realize that my project was actually much harder to realize 00:03:12.927 --> 00:03:14.982 than I initially had thought it to be. NOTE Paragraph 00:03:14.982 --> 00:03:18.476 First, I had to create a wearable sensor that was thin and flexible enough 00:03:18.476 --> 00:03:21.237 to be worn comfortably on the bottom of the patient's foot. 00:03:21.237 --> 00:03:24.656 After extensive research and testing of different materials like rubber, 00:03:24.656 --> 00:03:28.191 which I realized was too thick to be worn snugly on the bottom of the foot, 00:03:28.191 --> 00:03:30.998 I decided to print a film sensor with electrically conducted 00:03:30.998 --> 00:03:32.660 pressure sensitive ink particles. 00:03:32.660 --> 00:03:36.236 Once pressure is applied, the connectivity between the particles increases. 00:03:36.236 --> 00:03:39.260 Therefore, I could design a circuit that would measure pressure 00:03:39.260 --> 00:03:40.967 by measuring electrical resistance. NOTE Paragraph 00:03:41.267 --> 00:03:44.026 Next, I had to design a wearable wireless circuit, 00:03:44.026 --> 00:03:47.338 but wireless [???] transmission consumes lots of power 00:03:47.338 --> 00:03:49.211 and requires heavy, bulky batteries. 00:03:49.211 --> 00:03:52.728 Thankfully, I was able to find out about the blue tooth energy technology, 00:03:52.728 --> 00:03:56.251 which consumes very little power and can be driven by a coin-sized battery. 00:03:56.251 --> 00:03:59.880 This prevented the system from dying in the middle of the night. NOTE Paragraph 00:03:59.880 --> 00:04:03.343 Lastly, I had to code a smartphone app that would essentially transform 00:04:03.343 --> 00:04:05.848 the care-giver's smartphone into a remote monitor. 00:04:05.848 --> 00:04:07.301 For this, I had to expand upon 00:04:07.301 --> 00:04:09.497 my knowledge of coding with Java and S Code, 00:04:09.497 --> 00:04:12.984 and I also had to learn about how to encode for bluetooth energy devices 00:04:12.984 --> 00:04:15.860 by watching YouTube tutorials and reading various textbooks. NOTE Paragraph 00:04:17.230 --> 00:04:21.019 Integrating these components, I was able to successfully create two prototypes, 00:04:21.019 --> 00:04:23.347 one in which the sensor is embedded inside a sock, 00:04:23.347 --> 00:04:25.793 and another that's a re-attachable sensor assembly 00:04:25.793 --> 00:04:28.029 that can be adhered anywhere that makes contact 00:04:28.029 --> 00:04:29.852 with the bottom of the patient's foot. 00:04:29.852 --> 00:04:32.872 I've tested the device on my grandfather for about a year now, 00:04:32.872 --> 00:04:36.543 and it's had a 100 percent success rate in detecting the over 900 known cases 00:04:36.543 --> 00:04:38.089 of his wandering. 00:04:38.629 --> 00:04:41.052 Last summer, I was able to beta test my device 00:04:41.052 --> 00:04:43.598 at several residential care facilities in California, 00:04:43.598 --> 00:04:45.770 and I'm currently incorporating the feedback 00:04:45.770 --> 00:04:48.733 to further improve the device into a marketable product. 00:04:48.733 --> 00:04:50.841 Testing the device on a number of patients 00:04:50.841 --> 00:04:53.350 made me realize that I need to invent solutions 00:04:53.350 --> 00:04:56.235 for people who didn't want to wear socks to sleep at night. NOTE Paragraph 00:04:56.805 --> 00:04:59.630 So sensor data, collected on a vast number of patients, 00:04:59.630 --> 00:05:01.959 can be useful for improving patient care 00:05:01.959 --> 00:05:04.777 and also leading to a cure for the disease, possibly. 00:05:04.777 --> 00:05:06.620 For example, I'm currently examining 00:05:06.620 --> 00:05:09.848 correlations between the frequency of a patient's nightly wandering 00:05:09.848 --> 00:05:12.714 and his or her daily activities and diet. NOTE Paragraph 00:05:13.854 --> 00:05:16.615 One thing I'll never forget is when my device first caught 00:05:16.615 --> 00:05:18.833 my grandfather's wandering out of bed at night. 00:05:18.833 --> 00:05:21.784 At that moment, I was really struck by the power of technology 00:05:21.784 --> 00:05:23.761 to change lives for the better. 00:05:24.011 --> 00:05:26.131 People living happily and healthfully: 00:05:26.131 --> 00:05:28.156 that's the world that I imagine. NOTE Paragraph 00:05:28.156 --> 00:05:30.216 Thank you very much. NOTE Paragraph 00:05:30.216 --> 00:05:33.526 (Applause)