0:00:00.771,0:00:04.135 What's the fastest growing threat[br]to Americans' health? 0:00:04.135,0:00:06.973 Cancer? Heart attacks? Diabetes? 0:00:07.603,0:00:09.449 The answer is actually none of these: 0:00:09.449,0:00:11.250 it's Alzheimer's disease. 0:00:11.250,0:00:13.276 Every 67 seconds, 0:00:13.276,0:00:16.921 someone in the United States[br]is diagnosed with Alzheimer's. 0:00:16.921,0:00:20.149 As the number of Alzheimer's patients[br]triples by the year 2050, 0:00:20.149,0:00:23.446 caring for them, as well as[br]the rest of the aging population, 0:00:23.446,0:00:26.005 will become an overwhelming[br]society challenge. 0:00:26.585,0:00:28.465 My family has experienced firsthand 0:00:28.465,0:00:30.967 the struggles of caring[br]for an Alzheimer's patient. 0:00:30.967,0:00:33.107 Growing up in a family[br]with three generations, 0:00:33.107,0:00:35.262 I've always been very close[br]to my grandfather. 0:00:35.262,0:00:36.689 When I was four years old, 0:00:36.689,0:00:39.192 my grandfather and I [br]were walking in a park in Japan 0:00:39.192,0:00:40.497 when he suddenly got lost. 0:00:40.497,0:00:43.730 It was one of the scariest moments[br]I've ever experienced in my life, 0:00:43.730,0:00:47.167 and it was also the first instance[br]that informed us that my grandfather 0:00:47.167,0:00:48.412 had Alzheimer's disease. 0:00:48.942,0:00:52.025 Over the past 12 years,[br]his condition got worse and worse, 0:00:52.025,0:00:55.823 and his wandering in particular[br]caused my family a lot of stress. 0:00:55.823,0:00:57.302 My aunt, his primary caregiver, 0:00:57.302,0:01:00.349 really struggled to stay awake at night[br]to keep an eye on him, 0:01:00.349,0:01:03.047 and even then often failed[br]to catch him leaving the bed. 0:01:03.047,0:01:05.858 I became really concerned[br]about my aunt's well-being 0:01:05.858,0:01:07.599 as well as my grandfather's safety. 0:01:07.599,0:01:11.150 I searched extensively for a solution[br]that could help my family's problems, 0:01:11.150,0:01:12.450 but couldn't find one. 0:01:12.960,0:01:15.693 Then, one night about two years ago, 0:01:15.693,0:01:19.158 I was looking after my grandfather[br]and I saw him stepping out of the bed. 0:01:19.158,0:01:21.150 The moment his foot landed on the floor, 0:01:21.150,0:01:24.412 I thought, why don't I put[br]a pressure sensor on the heel of his foot? 0:01:24.412,0:01:26.809 Once he stepped onto the floor[br]and out of the bed, 0:01:26.809,0:01:30.516 the pressure sensor would detect an[br]increase in pressure caused by body weight 0:01:30.516,0:01:33.971 and then wirelessly send an audible alert[br]to the caregiver's smart phone. 0:01:33.971,0:01:36.312 That way, my aunt could sleep[br]much better at night 0:01:36.312,0:01:39.002 without having to worry[br]about my grandfather's wandering. 0:01:39.002,0:01:42.934 So now I'd like to perform[br]a demonstration of this sock. 0:01:45.134,0:01:47.802 Could I please have[br]my sock model on the stage? 0:01:48.831,0:01:50.560 Great. 0:01:52.590,0:01:56.727 So once the patient steps onto the floor, 0:01:57.567,0:02:00.182 an alert is sent[br]to the caregiver's smartphone. 0:02:04.571,0:02:06.057 Thank you. (Applause) 0:02:06.057,0:02:09.225 Thank you sock model. 0:02:12.045,0:02:14.489 So this is a drawing[br]of my preliminary design. 0:02:15.819,0:02:18.441 My desire to create[br]a sensor-based technology 0:02:18.441,0:02:21.969 perhaps stemmed from my life-long love[br]for sensors and technology. 0:02:22.449,0:02:24.925 When I was six years old,[br]an elderly family friend 0:02:24.925,0:02:27.498 fell down in the bathroom[br]and suffered severe injuries. 0:02:27.498,0:02:29.606 I became concerned[br]about my own grandparents 0:02:29.606,0:02:32.108 and decided to invent[br]a smart bathroom system. 0:02:32.108,0:02:35.566 Motion sensors would be installed[br]inside the tiles of bathroom floors 0:02:35.566,0:02:39.404 to detect the falls of elderly patients[br]whenever they fell down in the bathroom. 0:02:39.404,0:02:41.416 Since I was only six years old at the time 0:02:41.416,0:02:43.739 and I hadn't graduated[br]from kindergarten yet, 0:02:43.739,0:02:48.073 I didn't have the necessary resources and [br]tools to translate my idea into reality, 0:02:48.073,0:02:50.706 but nonetheless, my research experience 0:02:50.706,0:02:54.957 really implanted in my a firm desire[br]to use sensors to help the elderly people. 0:02:54.957,0:02:58.003 I really believed that sensors[br]could improve the quality of life 0:02:58.003,0:02:59.694 of the elderly. 0:03:01.254,0:03:04.675 When I laid out my plan, I realized[br]that I faced three main challenges: 0:03:04.675,0:03:06.194 first, creating a sensor; 0:03:06.194,0:03:07.773 second, designing a circuit; 0:03:07.773,0:03:09.519 and third, coding a smartphone app. 0:03:09.519,0:03:12.927 This made me realize that my project[br]was actually much harder to realize 0:03:12.927,0:03:14.982 than I initially had thought it to be. 0:03:14.982,0:03:18.476 First, I had to create a wearable sensor[br]that was thin and flexible enough[br] 0:03:18.476,0:03:21.237 to be worn comfortably[br]on the bottom of the patient's foot. 0:03:21.237,0:03:24.656 After extensive research and testing[br]of different materials like rubber, 0:03:24.656,0:03:28.191 which I realized was too thick to be worn[br]snugly on the bottom of the foot, 0:03:28.191,0:03:30.998 I decided to print a film sensor[br]with electrically conducted 0:03:30.998,0:03:32.660 pressure sensitive ink particles. 0:03:32.660,0:03:36.236 Once pressure is applied, the connectivity[br]between the particles increases. 0:03:36.236,0:03:39.260 Therefore, I could design a circuit[br]that would measure pressure 0:03:39.260,0:03:40.967 by measuring electrical resistance. 0:03:41.267,0:03:44.026 Next, I had to design[br]a wearable wireless circuit, 0:03:44.026,0:03:47.338 but wireless [???] transmission[br]consumes lots of power 0:03:47.338,0:03:49.211 and requires heavy, bulky batteries. 0:03:49.211,0:03:52.728 Thankfully, I was able to find out[br]about the blue tooth energy technology, 0:03:52.728,0:03:56.251 which consumes very little power[br]and can be driven by a coin-sized battery. 0:03:56.251,0:03:59.880 This prevented the system[br]from dying in the middle of the night. 0:03:59.880,0:04:03.343 Lastly, I had to code a smartphone app[br]that would essentially transform 0:04:03.343,0:04:05.848 the care-giver's smartphone[br]into a remote monitor. 0:04:05.848,0:04:07.301 For this, I had to expand upon 0:04:07.301,0:04:09.497 my knowledge of coding[br]with Java and S Code, 0:04:09.497,0:04:12.984 and I also had to learn about how[br]to encode for bluetooth energy devices 0:04:12.984,0:04:15.860 by watching YouTube tutorials[br]and reading various textbooks. 0:04:17.230,0:04:21.019 Integrating these components, I was able[br]to successfully create two prototypes, 0:04:21.019,0:04:23.347 one in which the sensor[br]is embedded inside a sock, 0:04:23.347,0:04:25.793 and another that's[br]a re-attachable sensor assembly 0:04:25.793,0:04:28.029 that can be adhered anywhere[br]that makes contact 0:04:28.029,0:04:29.852 with the bottom of the patient's foot. 0:04:29.852,0:04:32.872 I've tested the device on my grandfather[br]for about a year now, 0:04:32.872,0:04:36.543 and it's had a 100 percent success rate[br]in detecting the over 900 known cases 0:04:36.543,0:04:38.089 of his wandering. 0:04:38.629,0:04:41.052 Last summer, I was able[br]to beta test my device 0:04:41.052,0:04:43.598 at several residential[br]care facilities in California, 0:04:43.598,0:04:45.770 and I'm currently incorporating[br]the feedback 0:04:45.770,0:04:48.733 to further improve the device [br]into a marketable product. 0:04:48.733,0:04:50.841 Testing the device on a number of patients 0:04:50.841,0:04:53.350 made me realize that I need[br]to invent solutions 0:04:53.350,0:04:56.235 for people who didn't want[br]to wear socks to sleep at night. 0:04:56.805,0:04:59.630 So sensor data, collected[br]on a vast number of patients, 0:04:59.630,0:05:01.959 can be useful for improving patient care 0:05:01.959,0:05:04.777 and also leading to a cure[br]for the disease, possibly. 0:05:04.777,0:05:06.620 For example, I'm currently examining [br] 0:05:06.620,0:05:09.848 correlations between the frequency[br]of a patient's nightly wandering 0:05:09.848,0:05:12.714 and his or her daily activities and diet. 0:05:13.854,0:05:16.615 One thing I'll never forget[br]is when my device first caught 0:05:16.615,0:05:18.833 my grandfather's wandering[br]out of bed at night. 0:05:18.833,0:05:21.784 At that moment, I was really struck[br]by the power of technology 0:05:21.784,0:05:23.761 to change lives for the better. 0:05:24.011,0:05:26.131 People living happily and healthfully: 0:05:26.131,0:05:28.156 that's the world that I imagine. 0:05:28.156,0:05:30.216 Thank you very much. 0:05:30.216,0:05:33.526 (Applause)