WEBVTT 00:00:00.441 --> 00:00:04.685 What's the fastest growing threat to Americans' health? 00:00:04.685 --> 00:00:07.773 Cancer? Heart attacks? Diabetes? 00:00:07.773 --> 00:00:09.979 The answer is actually none of these: 00:00:09.979 --> 00:00:11.650 it's Alzheimer's disease. 00:00:11.650 --> 00:00:13.276 Every 67 seconds, 00:00:13.276 --> 00:00:16.921 someone in the United States is diagnosed with Alzheimer's. 00:00:16.921 --> 00:00:20.659 As the number of Alzheimer's patients triples by the year 2050, 00:00:20.659 --> 00:00:23.446 caring for them, as well as the rest of the aging population, 00:00:23.446 --> 00:00:26.185 will become an overwhelming society challenge. NOTE Paragraph 00:00:26.185 --> 00:00:29.575 My family has experienced firsthand the struggles of caring 00:00:29.575 --> 00:00:31.387 for an Alzheimer's patient. 00:00:31.387 --> 00:00:33.337 Growing up in a family with three generations, 00:00:33.337 --> 00:00:35.612 I've always been very close to my grandfather. 00:00:35.612 --> 00:00:37.879 When I was four years old, my grandfather and I 00:00:37.879 --> 00:00:39.272 were walking in a park in Japan 00:00:39.272 --> 00:00:40.967 when he suddenly got lost. 00:00:40.967 --> 00:00:43.730 It was one of the scariest moments I've ever experienced in my life, 00:00:43.730 --> 00:00:46.517 and it was also the first instance that informed us that my grandfather 00:00:46.517 --> 00:00:48.792 had Alzheimer's disease. 00:00:48.792 --> 00:00:52.275 Over the past 12 years, his condition got worse and worse, 00:00:52.275 --> 00:00:56.013 and his wandering in particular caused my family a lot of stress. 00:00:56.013 --> 00:00:57.522 My aunt, his primary caregiver, 00:00:57.522 --> 00:01:00.239 really struggled to stay awake at night to keep an eye on him, 00:01:00.239 --> 00:01:03.327 and even then often failed to catch him leaving the bed. 00:01:03.327 --> 00:01:05.858 I became really concerned about my aunt's well-being 00:01:05.858 --> 00:01:08.009 as well as my grandfather's safety. 00:01:08.009 --> 00:01:11.260 I searched extensively for a solution that could help my family's problems, 00:01:11.260 --> 00:01:13.280 but couldn't find one. NOTE Paragraph 00:01:13.280 --> 00:01:15.973 Then, one night about two years ago, 00:01:15.973 --> 00:01:19.758 I was looking after my grandfather and I saw him stepping out of the bed. 00:01:19.758 --> 00:01:21.360 The moment his foot landed on the floor, 00:01:21.360 --> 00:01:24.982 I thought, why don't I put a pressure sensor on the heel of his foot? 00:01:24.982 --> 00:01:27.049 Once he stepped onto the floor and out of the bed, 00:01:27.049 --> 00:01:30.276 the pressure sensor would detect an increase in pressure caused by body weight 00:01:30.276 --> 00:01:32.691 and then wirelessly send an audible alert to the caregiver's smart phone. 00:01:32.691 --> 00:01:36.452 That way, my aunt could sleep much better at night 00:01:36.452 --> 00:01:39.192 without having to worry about my grandfather's wandering. NOTE Paragraph 00:01:39.192 --> 00:01:43.604 So now I'd like to perform a demonstration of this sock. 00:01:45.554 --> 00:01:47.992 Could I please have my sock model on the stage? 00:01:48.991 --> 00:01:51.080 Great. 00:01:52.590 --> 00:01:57.837 So once the patient steps onto the floor, 00:01:57.837 --> 00:02:00.182 an alert is sent to the caregiver's smartphone. NOTE Paragraph 00:02:04.571 --> 00:02:06.057 Thank you. (Applause) NOTE Paragraph 00:02:06.057 --> 00:02:12.535 Thank you sock model. NOTE Paragraph 00:02:12.535 --> 00:02:15.739 So this is a drawing of my preliminary design. NOTE Paragraph 00:02:15.739 --> 00:02:18.711 My desire to create a sensor-based technology 00:02:18.711 --> 00:02:22.449 perhaps stemmed from my life-long love for sensors and technology. 00:02:22.449 --> 00:02:24.725 When I was six years old, an elderly family friend 00:02:24.725 --> 00:02:27.488 fell down in the bathroom and suffered severe injuries. 00:02:27.488 --> 00:02:29.276 I became concerned about my own grandparents 00:02:29.276 --> 00:02:32.108 and decided to invent a smart bathroom system. 00:02:32.108 --> 00:02:35.916 Motion sensors would be installed inside the tiles of bathroom floors 00:02:35.916 --> 00:02:39.864 to detect the falls of elderly patients whenever they fell down in the bathroom. 00:02:39.864 --> 00:02:41.976 Since I was only six years old at the time 00:02:41.976 --> 00:02:44.089 and I hadn't graduated from kindergarten yet, 00:02:44.089 --> 00:02:47.294 I didn't have the necessary resources and tools 00:02:47.294 --> 00:02:48.803 to translate my idea into reality, 00:02:48.803 --> 00:02:51.636 but nonetheless, my research experience 00:02:51.636 --> 00:02:55.467 really planted in my a firm desire to use sensors to help the elderly people. 00:02:55.467 --> 00:02:58.323 I really believed that sensors could improve the quality of life 00:02:58.323 --> 00:03:01.364 of the elderly. NOTE Paragraph 00:03:01.364 --> 00:03:04.615 When I laid out my plan, I realized that I faced three main challenges: 00:03:04.615 --> 00:03:06.194 first, creating a sensor; 00:03:06.194 --> 00:03:07.773 second, design a circuit; 00:03:07.773 --> 00:03:09.909 and third, coding a smartphone app. 00:03:09.909 --> 00:03:13.067 This made me realize that my project was actually much harder to realize 00:03:13.067 --> 00:03:15.412 than I initially had thought it to be. NOTE Paragraph 00:03:15.412 --> 00:03:18.546 First, I had to create a wearable sensor that was thin and flexible enough 00:03:18.546 --> 00:03:21.147 to be worn comfortably on the bottom of the patient's foot. 00:03:21.147 --> 00:03:24.236 After extensive research and testing of different materials like rubber, 00:03:24.236 --> 00:03:27.741 which I realized was too thick to be worn snugly on the bottom of the foot, 00:03:27.741 --> 00:03:30.388 I decided to print a film sensor with electrically conducted 00:03:30.388 --> 00:03:32.640 pressure sensitive ink particles. 00:03:32.640 --> 00:03:36.286 Once pressure is applied, the connectivity between the particles increases. 00:03:36.286 --> 00:03:38.840 Therefore, I could design a circuit that would measure pressure 00:03:38.840 --> 00:03:41.487 by measuring electrical resistance. NOTE Paragraph 00:03:41.487 --> 00:03:44.366 Next, I had to design a wearable wireless circuit, 00:03:44.366 --> 00:03:47.338 but wireless [???] transmission consumes lots of power 00:03:47.338 --> 00:03:49.521 and requires heavy, bulky batteries. 00:03:49.521 --> 00:03:52.748 Thankfully, I was able to find out about the blue tooth energy technology, 00:03:52.748 --> 00:03:57.531 which consumes very little power and can be driven by a coin-sized battery. 00:03:57.531 --> 00:04:00.410 This prevented the system from dying in the middle of the night. NOTE Paragraph 00:04:00.410 --> 00:04:03.313 Lastly, I had to code a smartphone app that would essentially transform 00:04:03.313 --> 00:04:06.238 the care-giver's smartphone into a remote monitor. 00:04:06.238 --> 00:04:07.631 For this, I had to expand upon 00:04:07.631 --> 00:04:09.767 my knowledge of coding with Java and S Code, 00:04:09.767 --> 00:04:13.134 and I also had to learn about how to encode for bluetooth energy devices 00:04:13.134 --> 00:04:16.710 by watching YouTube tutorials and reading various textbooks. NOTE Paragraph 00:04:16.710 --> 00:04:20.889 Integrating these components, I was able to successfully create two prototypes, 00:04:20.889 --> 00:04:23.467 one in which the sensor is embedded inside a sock, 00:04:23.467 --> 00:04:25.603 and another that's a re-attachable sensor assembly 00:04:25.603 --> 00:04:27.669 that can be adhered anywhere that makes contact 00:04:27.669 --> 00:04:29.852 with the bottom of the patient's foot. 00:04:29.852 --> 00:04:32.522 I've tested the device on my grandfather for about a year now, 00:04:32.522 --> 00:04:36.423 and it's had a 100 percent success rate in detecting the over 900 known cases 00:04:36.423 --> 00:04:38.629 of his wandering. 00:04:38.629 --> 00:04:41.322 Last summer, I was able to beta test my device 00:04:41.322 --> 00:04:44.178 at several residential care facilities in California, 00:04:44.178 --> 00:04:47.080 and I'm currently incorporating the feedback to further improve the device 00:04:47.080 --> 00:04:49.193 into a marketable product. 00:04:49.193 --> 00:04:51.121 Testing the device on a number of patients 00:04:51.121 --> 00:04:53.350 made me realize that I need to invent solutions 00:04:53.350 --> 00:04:56.925 for people who didn't want to wear socks to sleep at night. NOTE Paragraph 00:04:56.925 --> 00:04:59.620 So sensor data, collected on a vast number of patients, 00:04:59.620 --> 00:05:02.359 can be useful for improving patient care 00:05:02.359 --> 00:05:05.447 and also leading to a cure for the disease, possibly. 00:05:05.447 --> 00:05:06.840 For example, I'm currently examining 00:05:06.840 --> 00:05:09.928 correlations between the frequency of a patient's nightly wandering 00:05:09.928 --> 00:05:12.714 and his or her daily activities and diet. NOTE Paragraph 00:05:12.714 --> 00:05:16.615 One thing I'll never forget is when my device first caught 00:05:16.615 --> 00:05:19.123 my grandfather's wandering out of bed at night. 00:05:19.123 --> 00:05:22.234 At that moment, I was really struck by the power of the technology 00:05:22.234 --> 00:05:24.161 to change lives for the better. 00:05:24.161 --> 00:05:26.251 People living happily and healthfully: 00:05:26.251 --> 00:05:28.156 that's the world that I imagine. NOTE Paragraph 00:05:28.156 --> 00:05:30.216 Thank you very much. NOTE Paragraph 00:05:30.216 --> 00:05:33.526 (Applause)