1 00:00:00,744 --> 00:00:04,685 What's the fastest growing threat to Americans' health? 2 00:00:04,685 --> 00:00:07,773 Cancer? Heart attacks? Diabetes? 3 00:00:07,773 --> 00:00:09,979 The answer is actually none of these: 4 00:00:09,979 --> 00:00:11,650 it's Alzheimer's disease. 5 00:00:11,650 --> 00:00:13,276 Every 67 seconds, 6 00:00:13,276 --> 00:00:16,921 someone in the United States is diagnosed with Alzheimer's. 7 00:00:16,921 --> 00:00:20,659 As the number of Alzheimer's patients triples by the year 2050, 8 00:00:20,659 --> 00:00:23,446 caring for them, as well as the rest of the aging population, 9 00:00:23,446 --> 00:00:26,185 will become an overwhelming society challenge. 10 00:00:26,185 --> 00:00:29,575 My family has experienced firsthand the struggles of caring 11 00:00:29,575 --> 00:00:31,387 for an Alzheimer's patient. 12 00:00:31,387 --> 00:00:33,337 Growing up in a family with three generations, 13 00:00:33,337 --> 00:00:35,612 I've always been very close to my grandfather. 14 00:00:35,612 --> 00:00:37,879 When I was four years old, my grandfather and I 15 00:00:37,879 --> 00:00:39,272 were walking in a park in Japan 16 00:00:39,272 --> 00:00:40,967 when he suddenly got lost. 17 00:00:40,967 --> 00:00:43,730 It was one of the scariest moments I've ever experienced in my life, 18 00:00:43,730 --> 00:00:46,517 and it was also the first instance that informed us that my grandfather 19 00:00:46,517 --> 00:00:48,792 had Alzheimer's disease. 20 00:00:48,792 --> 00:00:52,275 Over the past 12 years, his condition got worse and worse, 21 00:00:52,275 --> 00:00:56,013 and his wandering in particular caused my family a lot of stress. 22 00:00:56,013 --> 00:00:57,522 My aunt, his primary caregiver, 23 00:00:57,522 --> 00:01:00,239 really struggled to stay awake at night to keep an eye on him, 24 00:01:00,239 --> 00:01:03,327 and even then often failed to catch him leaving the bed. 25 00:01:03,327 --> 00:01:05,858 I became really concerned about my aunt's well-being 26 00:01:05,858 --> 00:01:08,009 as well as my grandfather's safety. 27 00:01:08,009 --> 00:01:11,260 I searched extensively for a solution that could help my family's problems, 28 00:01:11,260 --> 00:01:13,280 but couldn't find one. 29 00:01:13,280 --> 00:01:15,973 Then, one night about two years ago, 30 00:01:15,973 --> 00:01:19,758 I was looking after my grandfather and I saw him stepping out of the bed. 31 00:01:19,758 --> 00:01:21,360 The moment his foot landed on the floor, 32 00:01:21,360 --> 00:01:24,982 I thought, why don't I put a pressure sensor on the heel of his foot? 33 00:01:24,982 --> 00:01:27,049 Once he stepped onto the floor and out of the bed, 34 00:01:27,049 --> 00:01:30,276 the pressure sensor would detect an increase in pressure caused by body weight 35 00:01:30,276 --> 00:01:32,691 and then wirelessly send an audible alert to the caregiver's smart phone. 36 00:01:32,691 --> 00:01:36,452 That way, my aunt could sleep much better at night 37 00:01:36,452 --> 00:01:39,192 without having to worry about my grandfather's wandering. 38 00:01:39,192 --> 00:01:43,604 So now I'd like to perform a demonstration of this sock. 39 00:01:45,554 --> 00:01:47,992 Could I please have my sock model on the stage? 40 00:01:48,991 --> 00:01:51,080 Great. 41 00:01:52,590 --> 00:01:57,837 So once the patient steps onto the floor, 42 00:01:57,837 --> 00:02:00,182 an alert is sent to the caregiver's smartphone. 43 00:02:04,571 --> 00:02:06,057 Thank you. (Applause) 44 00:02:06,057 --> 00:02:12,535 Thank you sock model. 45 00:02:12,535 --> 00:02:15,739 So this is a drawing of my preliminary design. 46 00:02:15,739 --> 00:02:18,711 My desire to create a sensor-based technology 47 00:02:18,711 --> 00:02:22,449 perhaps stemmed from my life-long love for sensors and technology. 48 00:02:22,449 --> 00:02:24,725 When I was six years old, an elderly family friend 49 00:02:24,725 --> 00:02:27,488 fell down in the bathroom and suffered severe injuries. 50 00:02:27,488 --> 00:02:29,276 I became concerned about my own grandparents 51 00:02:29,276 --> 00:02:32,108 and decided to invent a smart bathroom system. 52 00:02:32,108 --> 00:02:35,916 Motion sensors would be installed inside the tiles of bathroom floors 53 00:02:35,916 --> 00:02:39,864 to detect the falls of elderly patients whenever they fell down in the bathroom. 54 00:02:39,864 --> 00:02:41,976 Since I was only six years old at the time 55 00:02:41,976 --> 00:02:44,089 and I hadn't graduated from kindergarten yet, 56 00:02:44,089 --> 00:02:47,294 I didn't have the necessary resources and tools 57 00:02:47,294 --> 00:02:48,803 to translate my idea into reality, 58 00:02:48,803 --> 00:02:51,636 but nonetheless, my research experience 59 00:02:51,636 --> 00:02:55,467 really planted in my a firm desire to use sensors to help the elderly people. 60 00:02:55,467 --> 00:02:58,323 I really believed that sensors could improve the quality of life 61 00:02:58,323 --> 00:03:01,364 of the elderly. 62 00:03:01,364 --> 00:03:04,615 When I laid out my plan, I realized that I faced three main challenges: 63 00:03:04,615 --> 00:03:06,194 first, creating a sensor; 64 00:03:06,194 --> 00:03:07,773 second, design a circuit; 65 00:03:07,773 --> 00:03:09,909 and third, coding a smartphone app. 66 00:03:09,909 --> 00:03:13,067 This made me realize that my project was actually much harder to realize 67 00:03:13,067 --> 00:03:15,412 than I initially had thought it to be. 68 00:03:15,412 --> 00:03:18,546 First, I had to create a wearable sensor that was thin and flexible enough 69 00:03:18,546 --> 00:03:21,147 to be worn comfortably on the bottom of the patient's foot. 70 00:03:21,147 --> 00:03:24,236 After extensive research and testing of different materials like rubber, 71 00:03:24,236 --> 00:03:27,741 which I realized was too thick to be worn snugly on the bottom of the foot, 72 00:03:27,741 --> 00:03:30,388 I decided to print a film sensor with electrically conducted 73 00:03:30,388 --> 00:03:32,640 pressure sensitive ink particles. 74 00:03:32,640 --> 00:03:36,286 Once pressure is applied, the connectivity between the particles increases. 75 00:03:36,286 --> 00:03:38,840 Therefore, I could design a circuit that would measure pressure 76 00:03:38,840 --> 00:03:41,487 by measuring electrical resistance. 77 00:03:41,487 --> 00:03:44,366 Next, I had to design a wearable wireless circuit, 78 00:03:44,366 --> 00:03:47,338 but wireless [???] transmission consumes lots of power 79 00:03:47,338 --> 00:03:49,521 and requires heavy, bulky batteries. 80 00:03:49,521 --> 00:03:52,748 Thankfully, I was able to find out about the blue tooth energy technology, 81 00:03:52,748 --> 00:03:57,531 which consumes very little power and can be driven by a coin-sized battery. 82 00:03:57,531 --> 00:04:00,410 This prevented the system from dying in the middle of the night. 83 00:04:00,410 --> 00:04:03,313 Lastly, I had to code a smartphone app that would essentially transform 84 00:04:03,313 --> 00:04:06,238 the care-giver's smartphone into a remote monitor. 85 00:04:06,238 --> 00:04:07,631 For this, I had to expand upon 86 00:04:07,631 --> 00:04:09,767 my knowledge of coding with Java and S Code, 87 00:04:09,767 --> 00:04:13,134 and I also had to learn about how to encode for bluetooth energy devices 88 00:04:13,134 --> 00:04:16,710 by watching YouTube tutorials and reading various textbooks. 89 00:04:16,710 --> 00:04:20,889 Integrating these components, I was able to successfully create two prototypes, 90 00:04:20,889 --> 00:04:23,467 one in which the sensor is embedded inside a sock, 91 00:04:23,467 --> 00:04:25,603 and another that's a re-attachable sensor assembly 92 00:04:25,603 --> 00:04:27,669 that can be adhered anywhere that makes contact 93 00:04:27,669 --> 00:04:29,852 with the bottom of the patient's foot. 94 00:04:29,852 --> 00:04:32,522 I've tested the device on my grandfather for about a year now, 95 00:04:32,522 --> 00:04:36,423 and it's had a 100 percent success rate in detecting the over 900 known cases 96 00:04:36,423 --> 00:04:38,629 of his wandering. 97 00:04:38,629 --> 00:04:41,322 Last summer, I was able to beta test my device 98 00:04:41,322 --> 00:04:44,178 at several residential care facilities in California, 99 00:04:44,178 --> 00:04:47,080 and I'm currently incorporating the feedback to further improve the device 100 00:04:47,080 --> 00:04:49,193 into a marketable product. 101 00:04:49,193 --> 00:04:51,121 Testing the device on a number of patients 102 00:04:51,121 --> 00:04:53,350 made me realize that I need to invent solutions 103 00:04:53,350 --> 00:04:56,925 for people who didn't want to wear socks to sleep at night. 104 00:04:56,925 --> 00:04:59,620 So sensor data, collected on a vast number of patients, 105 00:04:59,620 --> 00:05:02,359 can be useful for improving patient care 106 00:05:02,359 --> 00:05:05,447 and also leading to a cure for the disease, possibly. 107 00:05:05,447 --> 00:05:06,840 For example, I'm currently examining 108 00:05:06,840 --> 00:05:09,928 correlations between the frequency of a patient's nightly wandering 109 00:05:09,928 --> 00:05:12,714 and his or her daily activities and diet. 110 00:05:12,714 --> 00:05:16,615 One thing I'll never forget is when my device first caught 111 00:05:16,615 --> 00:05:19,123 my grandfather's wandering out of bed at night. 112 00:05:19,123 --> 00:05:22,234 At that moment, I was really struck by the power of the technology 113 00:05:22,234 --> 00:05:24,161 to change lives for the better. 114 00:05:24,161 --> 00:05:26,251 People living happily and healthfully: 115 00:05:26,251 --> 00:05:28,225 that's the world that I imagine. 116 00:05:28,225 --> 00:05:33,263 Thank you very much. 117 99:59:59,999 --> 99:59:59,999 (Applause)