0:00:00.920,0:00:02.160 Just over a year ago, 0:00:02.840,0:00:05.216 for the third time in my life,[br]I ceased to exist. 0:00:05.240,0:00:09.520 I was having a small operation,[br]and my brain was filling with anesthetic. 0:00:10.520,0:00:13.856 I remember a sense[br]of detachment and falling apart 0:00:13.880,0:00:15.080 and a coldness. 0:00:15.880,0:00:18.296 And then I was back,[br]drowsy and disoriented, 0:00:18.320,0:00:19.760 but definitely there. 0:00:20.280,0:00:22.096 Now, when you wake from a deep sleep, 0:00:22.120,0:00:25.376 you might feel confused about the time[br]or anxious about oversleeping, 0:00:25.400,0:00:28.136 but there's always a basic sense[br]of time having passed, 0:00:28.160,0:00:30.376 of a continuity between then and now. 0:00:30.400,0:00:32.616 Coming round from[br]anesthesia is very different. 0:00:32.640,0:00:35.136 I could have been under[br]for five minutes, five hours, 0:00:35.160,0:00:36.576 five years or even 50 years. 0:00:36.600,0:00:38.056 I simply wasn't there. 0:00:38.080,0:00:39.320 It was total oblivion. 0:00:40.240,0:00:42.296 Anesthesia --[br]it's a modern kind of magic. 0:00:42.320,0:00:45.496 It turns people into objects, 0:00:45.520,0:00:47.520 and then, we hope, back again into people. 0:00:47.544,0:00:48.776 And in this process 0:00:48.800,0:00:52.040 is one of the greatest remaining[br]mysteries in science and philosophy. 0:00:52.400,0:00:54.016 How does consciousness happen? 0:00:54.040,0:00:56.256 Somehow, within each of our brains, 0:00:56.280,0:00:59.176 the combined activity[br]of many billions of neurons, 0:00:59.200,0:01:02.216 each one a tiny biological machine, 0:01:02.240,0:01:04.056 is generating a conscious experience. 0:01:04.080,0:01:06.016 And not just any conscious experience -- 0:01:06.040,0:01:08.421 your conscious experience[br]right here and right now. 0:01:08.445,0:01:09.645 How does this happen? 0:01:10.560,0:01:12.616 Answering this question is so important 0:01:12.640,0:01:15.496 because consciousness[br]for each of us is all there is. 0:01:15.520,0:01:17.520 Without it there's no world, 0:01:18.400,0:01:19.776 there's no self, 0:01:19.800,0:01:21.336 there's nothing at all. 0:01:21.360,0:01:23.313 And when we suffer, we suffer consciously 0:01:23.337,0:01:25.417 whether it's through[br]mental illness or pain. 0:01:26.400,0:01:29.336 And if we can experience[br]joy and suffering, 0:01:29.360,0:01:30.800 what about other animals? 0:01:31.320,0:01:32.736 Might they be conscious, too? 0:01:32.760,0:01:34.416 Do they also have a sense of self? 0:01:34.440,0:01:37.576 And as computers get faster and smarter, 0:01:37.600,0:01:40.176 maybe there will come a point,[br]maybe not too far away, 0:01:40.200,0:01:42.936 when my iPhone develops[br]a sense of its own existence. 0:01:42.960,0:01:47.440 I actually think the prospects[br]for a conscious AI are pretty remote. 0:01:47.960,0:01:50.336 And I think this because[br]my research is telling me 0:01:50.360,0:01:53.016 that consciousness has less to do[br]with pure intelligence 0:01:53.040,0:01:57.616 and more to do with our nature[br]as living and breathing organisms. 0:01:57.640,0:02:00.336 Consciousness and intelligence[br]are very different things. 0:02:00.360,0:02:03.920 You don't have to be smart to suffer,[br]but you probably do have to be alive. 0:02:05.200,0:02:06.896 In the story I'm going to tell you, 0:02:06.920,0:02:09.256 our conscious experiences[br]of the world around us, 0:02:09.280,0:02:10.616 and of ourselves within it, 0:02:10.639,0:02:13.176 are kinds of controlled hallucinations 0:02:13.200,0:02:17.040 that happen with, through[br]and because of our living bodies. 0:02:17.840,0:02:21.176 Now, you might have heard[br]that we know nothing 0:02:21.200,0:02:23.936 about how the brain and body[br]give rise to consciousness. 0:02:23.960,0:02:27.096 Some people even say it's beyond[br]the reach of science altogether. 0:02:27.120,0:02:28.336 But in fact, 0:02:28.360,0:02:32.496 the last 25 years have seen an explosion[br]of scientific work in this area. 0:02:32.520,0:02:35.296 If you come to my lab[br]at the University of Sussex, 0:02:35.320,0:02:38.480 you'll find scientists[br]from all different disciplines 0:02:39.200,0:02:41.120 and sometimes even philosophers. 0:02:41.800,0:02:45.776 All of us together trying to understand[br]how consciousness happens 0:02:45.800,0:02:47.520 and what happens when it goes wrong. 0:02:47.880,0:02:50.016 And the strategy is very simple. 0:02:50.040,0:02:52.016 I'd like you to think about consciousness 0:02:52.040,0:02:54.256 in the way that we've[br]come to think about life. 0:02:54.280,0:02:56.896 At one time, people thought[br]the property of being alive 0:02:56.920,0:02:59.536 could not be explained[br]by physics and chemistry -- 0:02:59.560,0:03:01.720 that life had to be[br]more than just mechanism. 0:03:02.480,0:03:04.376 But people no longer think that. 0:03:04.400,0:03:06.016 As biologists got on with the job 0:03:06.040,0:03:08.616 of explaining the properties[br]of living systems 0:03:08.640,0:03:10.456 in terms of physics and chemistry -- 0:03:10.480,0:03:13.536 things like metabolism,[br]reproduction, homeostasis -- 0:03:13.560,0:03:17.376 the basic mystery of what life is[br]started to fade away, 0:03:17.400,0:03:20.456 and people didn't propose[br]any more magical solutions, 0:03:20.480,0:03:22.480 like a force of life or an élan vital. 0:03:23.080,0:03:25.736 So as with life, so with consciousness. 0:03:25.760,0:03:28.056 Once we start explaining its properties 0:03:28.080,0:03:31.776 in terms of things happening[br]inside brains and bodies, 0:03:31.800,0:03:35.216 the apparently insoluble mystery[br]of what consciousness is 0:03:35.240,0:03:36.976 should start to fade away. 0:03:37.000,0:03:38.720 At least that's the plan. 0:03:39.280,0:03:40.536 So let's get started. 0:03:40.560,0:03:42.536 What are the properties of consciousness? 0:03:42.560,0:03:45.084 What should a science[br]of consciousness try to explain? 0:03:45.960,0:03:49.656 Well, for today I'd just like to think[br]of consciousness in two different ways. 0:03:49.680,0:03:52.056 There are experiences[br]of the world around us, 0:03:52.080,0:03:54.296 full of sights, sounds and smells, 0:03:54.320,0:03:58.240 there's multisensory, panoramic,[br]3D, fully immersive inner movie. 0:03:59.000,0:04:00.560 And then there's conscious self. 0:04:01.080,0:04:03.536 The specific experience[br]of being you or being me. 0:04:03.560,0:04:05.576 The lead character in this inner movie, 0:04:05.600,0:04:08.960 and probably the aspect of consciousness[br]we all cling to most tightly. 0:04:09.840,0:04:12.296 Let's start with experiences[br]of the world around us, 0:04:12.320,0:04:16.055 and with the important idea[br]of the brain as a prediction engine. 0:04:16.079,0:04:17.839 Imagine being a brain. 0:04:18.600,0:04:20.255 You're locked inside a bony skull, 0:04:20.279,0:04:22.496 trying to figure[br]what's out there in the world. 0:04:22.520,0:04:25.536 There's no lights inside the skull.[br]There's no sound either. 0:04:25.560,0:04:28.336 All you've got to go on[br]is streams of electrical impulses 0:04:28.360,0:04:31.536 which are only indirectly related[br]to things in the world, 0:04:31.560,0:04:32.760 whatever they may be. 0:04:33.520,0:04:35.656 So perception --[br]figuring out what's there -- 0:04:35.680,0:04:38.536 has to be a process of informed guesswork 0:04:38.560,0:04:41.696 in which the brain combines[br]these sensory signals 0:04:41.720,0:04:45.776 with its prior expectations or beliefs[br]about the way the world is 0:04:45.800,0:04:48.936 to form its best guess[br]of what caused those signals. 0:04:48.960,0:04:51.656 The brain doesn't hear sound or see light. 0:04:51.680,0:04:56.040 What we perceive is its best guess[br]of what's out there in the world. 0:04:57.040,0:04:59.960 Let me give you a couple[br]of examples of all this. 0:05:00.400,0:05:02.376 You might have seen this illusion before, 0:05:02.400,0:05:04.656 but I'd like you to think[br]about it in a new way. 0:05:04.680,0:05:06.736 If you look at those two patches, A and B, 0:05:06.760,0:05:10.080 they should look to you to be[br]very different shades of gray, right? 0:05:11.040,0:05:14.016 But they are in fact[br]exactly the same shade. 0:05:14.040,0:05:15.376 And I can illustrate this. 0:05:15.400,0:05:17.616 If I put up a second version[br]of the image here 0:05:17.640,0:05:20.656 and join the two patches[br]with a gray-colored bar, 0:05:20.680,0:05:22.336 you can see there's no difference. 0:05:22.360,0:05:24.136 It's exactly the same shade of gray. 0:05:24.160,0:05:25.816 And if you still don't believe me, 0:05:25.840,0:05:28.080 I'll bring the bar across[br]and join them up. 0:05:28.680,0:05:32.040 It's a single colored block of gray,[br]there's no difference at all. 0:05:32.760,0:05:34.456 This isn't any kind of magic trick. 0:05:34.480,0:05:35.896 It's the same shade of gray, 0:05:35.920,0:05:38.120 but take it away again,[br]and it looks different. 0:05:39.240,0:05:40.496 So what's happening here 0:05:40.520,0:05:43.336 is that the brain[br]is using its prior expectations 0:05:43.360,0:05:46.456 built deeply into the circuits[br]of the visual cortex 0:05:46.480,0:05:49.176 that a cast shadow dims[br]the appearance of a surface, 0:05:49.200,0:05:52.840 so that we see B as lighter[br]than it really is. 0:05:53.920,0:05:55.176 Here's one more example, 0:05:55.200,0:05:58.376 which shows just how quickly[br]the brain can use new predictions 0:05:58.400,0:06:00.696 to change what we consciously experience. 0:06:00.720,0:06:01.920 Have a listen to this. 0:06:03.440,0:06:06.480 (Distorted voice) 0:06:07.320,0:06:08.896 Sounded strange, right? 0:06:08.920,0:06:11.349 Have a listen again[br]and see if you can get anything. 0:06:11.760,0:06:14.720 (Distorted voice) 0:06:15.880,0:06:17.136 Still strange. 0:06:17.160,0:06:18.360 Now listen to this. 0:06:18.920,0:06:21.976 (Recording) Anil Seth: I think Brexit[br]is a really terrible idea. 0:06:22.000,0:06:23.336 (Laughter) 0:06:23.360,0:06:24.576 Which I do. 0:06:24.600,0:06:26.416 So you heard some words there, right? 0:06:26.440,0:06:29.536 Now listen to the first sound again.[br]I'm just going to replay it. 0:06:29.560,0:06:32.616 (Distorted voice) 0:06:32.640,0:06:35.136 Yeah? So you can now hear words there. 0:06:35.160,0:06:36.360 Once more for luck. 0:06:37.040,0:06:40.040 (Distorted voice) 0:06:41.000,0:06:43.256 OK, so what's going on here? 0:06:43.280,0:06:46.856 The remarkable thing is the sensory[br]information coming into the brain 0:06:46.880,0:06:48.080 hasn't changed at all. 0:06:48.680,0:06:51.216 All that's changed[br]is your brain's best guess 0:06:51.240,0:06:53.296 of the causes of that sensory information. 0:06:53.320,0:06:55.680 And that changes[br]what you consciously hear. 0:06:56.560,0:06:59.696 All this puts the brain[br]basis of perception 0:06:59.720,0:07:01.176 in a bit of a different light. 0:07:01.200,0:07:05.216 Instead of perception depending largely[br]on signals coming into the brain 0:07:05.240,0:07:06.776 from the outside world, 0:07:06.800,0:07:09.296 it depends as much, if not more, 0:07:09.320,0:07:13.240 on perceptual predictions[br]flowing in the opposite direction. 0:07:14.160,0:07:16.216 We don't just passively[br]perceive the world, 0:07:16.240,0:07:17.936 we actively generate it. 0:07:17.960,0:07:20.576 The world we experience[br]comes as much, if not more, 0:07:20.600,0:07:21.936 from the inside out 0:07:21.960,0:07:23.280 as from the outside in. 0:07:23.640,0:07:25.816 Let me give you[br]one more example of perception 0:07:25.840,0:07:28.720 as this active, constructive process. 0:07:29.400,0:07:34.536 Here we've combined immersive[br]virtual reality with image processing 0:07:34.560,0:07:37.536 to simulate the effects[br]of overly strong perceptual predictions 0:07:37.560,0:07:38.896 on experience. 0:07:38.920,0:07:41.816 In this panoramic video,[br]we've transformed the world -- 0:07:41.840,0:07:43.736 which is in this case Sussex campus -- 0:07:43.760,0:07:45.320 into a psychedelic playground. 0:07:45.760,0:07:49.616 We've processed the footage using[br]an algorithm based on Google's Deep Dream 0:07:49.640,0:07:53.736 to simulate the effects[br]of overly strong perceptual predictions. 0:07:53.760,0:07:55.376 In this case, to see dogs. 0:07:55.400,0:07:57.536 And you can see[br]this is a very strange thing. 0:07:57.560,0:07:59.656 When perceptual[br]predictions are too strong, 0:07:59.680,0:08:01.056 as they are here, 0:08:01.080,0:08:03.976 the result looks very much[br]like the kinds of hallucinations 0:08:04.000,0:08:06.016 people might report in altered states, 0:08:06.040,0:08:08.120 or perhaps even in psychosis. 0:08:09.120,0:08:10.787 Now, think about this for a minute. 0:08:11.160,0:08:16.256 If hallucination is a kind[br]of uncontrolled perception, 0:08:16.280,0:08:20.736 then perception right here and right now[br]is also a kind of hallucination, 0:08:20.760,0:08:22.776 but a controlled hallucination 0:08:22.800,0:08:25.696 in which the brain's predictions[br]are being reigned in 0:08:25.720,0:08:27.600 by sensory information from the world. 0:08:28.200,0:08:31.176 In fact, we're all[br]hallucinating all the time, 0:08:31.200,0:08:32.576 including right now. 0:08:32.600,0:08:35.416 It's just that when we agree[br]about our hallucinations, 0:08:35.440,0:08:36.640 we call that reality. 0:08:37.280,0:08:41.216 (Laughter) 0:08:41.240,0:08:44.576 Now I'm going to tell you[br]that your experience of being a self, 0:08:44.600,0:08:46.416 the specific experience of being you, 0:08:46.440,0:08:49.936 is also a controlled hallucination[br]generated by the brain. 0:08:49.960,0:08:51.976 This seems a very strange idea, right? 0:08:52.000,0:08:54.136 Yes, visual illusions[br]might deceive my eyes, 0:08:54.160,0:08:57.680 but how could I be deceived[br]about what it means to be me? 0:08:58.200,0:08:59.416 For most of us, 0:08:59.440,0:09:01.016 the experience of being a person 0:09:01.040,0:09:03.136 is so familiar, so unified[br]and so continuous 0:09:03.160,0:09:05.376 that it's difficult[br]not to take it for granted. 0:09:05.400,0:09:07.216 But we shouldn't take it for granted. 0:09:07.240,0:09:10.456 There are in fact many different ways[br]we experience being a self. 0:09:10.480,0:09:12.576 There's the experience of having a body 0:09:12.600,0:09:14.056 and of being a body. 0:09:14.080,0:09:16.216 There are experiences[br]of perceiving the world 0:09:16.240,0:09:17.880 from a first person point of view. 0:09:18.240,0:09:20.456 There are experiences[br]of intending to do things 0:09:20.480,0:09:23.200 and of being the cause of things[br]that happen in the world. 0:09:23.640,0:09:24.896 And there are experiences 0:09:24.920,0:09:28.816 of being a continuous[br]and distinctive person over time, 0:09:28.840,0:09:31.680 built from a rich set[br]of memories and social interactions. 0:09:32.200,0:09:33.496 Many experiments show, 0:09:33.520,0:09:35.856 and psychiatrists[br]and neurologists know very well, 0:09:35.880,0:09:38.776 that these different ways[br]in which we experience being a self 0:09:38.800,0:09:40.496 can all come apart. 0:09:40.520,0:09:43.416 What this means is[br]the basic background experience 0:09:43.440,0:09:48.016 of being a unified self is a rather[br]fragile construction of the brain. 0:09:48.040,0:09:50.696 Another experience,[br]which just like all others, 0:09:50.720,0:09:51.920 requires explanation. 0:09:52.720,0:09:54.496 So let's return to the bodily self. 0:09:54.520,0:09:57.256 How does the brain generate[br]the experience of being a body 0:09:57.280,0:09:58.536 and of having a body? 0:09:58.560,0:10:00.416 Well, just the same principles apply. 0:10:00.440,0:10:01.896 The brain makes its best guess 0:10:01.920,0:10:04.120 about what is and what is not[br]part of its body. 0:10:04.880,0:10:08.616 And there's a beautiful experiment[br]in neuroscience to illustrate this. 0:10:08.640,0:10:10.616 And unlike most neuroscience experiments, 0:10:10.640,0:10:12.136 this is one you can do at home. 0:10:12.160,0:10:14.056 All you need is one of these. 0:10:14.080,0:10:15.336 (Laughter) 0:10:15.360,0:10:16.800 And a couple of paintbrushes. 0:10:18.880,0:10:20.256 In the rubber hand illusion, 0:10:20.280,0:10:22.256 a person's real hand is hidden from view, 0:10:22.280,0:10:24.896 and that fake rubber hand[br]is placed in front of them. 0:10:24.920,0:10:28.176 Then both hands are simultaneously[br]stroked with a paintbrush 0:10:28.200,0:10:30.880 while the person stares at the fake hand. 0:10:31.320,0:10:33.296 Now, for most people, after a while, 0:10:33.320,0:10:35.416 this leads to the very uncanny sensation 0:10:35.440,0:10:38.040 that the fake hand[br]is in fact part of their body. 0:10:39.640,0:10:43.816 And the idea is that the congruence[br]between seeing touch and feeling touch 0:10:43.840,0:10:48.216 on an object that looks like hand[br]and is roughly where a hand should be, 0:10:48.240,0:10:51.016 is enough evidence for the brain[br]to make its best guess 0:10:51.040,0:10:54.256 that the fake hand[br]is in fact part of the body. 0:10:54.280,0:10:56.880 (Laughter) 0:11:03.240,0:11:05.496 So you can measure[br]all kinds of clever things. 0:11:05.520,0:11:08.816 You can measure skin conductance[br]and startle responses, 0:11:08.840,0:11:10.096 but there's no need. 0:11:10.120,0:11:13.056 It's clear the guy in blue[br]has assimilated the fake hand. 0:11:13.080,0:11:16.496 This means that even experiences[br]of what our body is 0:11:16.520,0:11:18.056 is a kind of best guessing -- 0:11:18.080,0:11:20.560 a kind of controlled[br]hallucination by the brain. 0:11:21.480,0:11:22.680 There's one more thing. 0:11:24.120,0:11:27.776 We don't just experience our bodies[br]as objects in the world from the outside, 0:11:27.800,0:11:29.536 we also experience them from within. 0:11:29.560,0:11:33.800 We all experience the sense[br]of being a body from the inside. 0:11:35.000,0:11:37.576 And sensory signals[br]coming from the inside of the body 0:11:37.600,0:11:41.656 are continually telling the brain[br]about the state of the internal organs, 0:11:41.680,0:11:44.336 how the heart is doing,[br]what the blood pressure is like, 0:11:44.360,0:11:45.576 lots of things. 0:11:45.600,0:11:48.080 This kind of perception,[br]which we call interoception, 0:11:48.840,0:11:50.096 is rather overlooked. 0:11:50.120,0:11:51.536 But it's critically important 0:11:51.560,0:11:54.896 because perception and regulation[br]of the internal state of the body -- 0:11:54.920,0:11:56.520 well, that's what keeps us alive. 0:11:57.400,0:11:59.816 Here's another version[br]of the rubber hand illusion. 0:11:59.840,0:12:01.336 This is from our lab at Sussex. 0:12:01.360,0:12:04.776 And here, people see[br]a virtual reality version of their hand, 0:12:04.800,0:12:06.176 which flashes red and back 0:12:06.200,0:12:09.456 either in time or out of time[br]with their heartbeat. 0:12:09.480,0:12:11.936 And when it's flashing[br]in time with their heartbeat, 0:12:11.960,0:12:15.080 people have a stronger sense[br]that it's in fact part of their body. 0:12:15.720,0:12:19.216 So experiences of having a body[br]are deeply grounded 0:12:19.240,0:12:21.640 in perceiving our bodies from within. 0:12:23.680,0:12:26.336 There's one last thing[br]I want to draw your attention to, 0:12:26.360,0:12:30.016 which is that experiences of the body[br]from the inside are very different 0:12:30.040,0:12:32.096 from experiences of the world around us. 0:12:32.120,0:12:34.816 When I look around me,[br]the world seems full of objects -- 0:12:34.840,0:12:37.016 tables, chairs, rubber hands, 0:12:37.040,0:12:38.776 people, you lot -- 0:12:38.800,0:12:40.776 even my own body in the world, 0:12:40.800,0:12:43.056 I can perceive it[br]as an object from the outside. 0:12:43.080,0:12:45.136 But my experiences[br]of the body from within, 0:12:45.160,0:12:46.576 they're not like that at all. 0:12:46.600,0:12:48.656 I don't perceive my kidneys here, 0:12:48.680,0:12:50.256 my liver here, 0:12:50.280,0:12:51.536 my spleen ... 0:12:51.560,0:12:53.456 I don't know where my spleen is, 0:12:53.480,0:12:54.856 but it's somewhere. 0:12:54.880,0:12:56.776 I don't perceive my insides as objects. 0:12:56.800,0:13:00.440 In fact, I don't experience them[br]much at all unless they go wrong. 0:13:01.400,0:13:02.880 And this is important, I think. 0:13:03.600,0:13:05.696 Perception of the internal[br]state of the body 0:13:05.720,0:13:07.576 isn't about figuring out what's there, 0:13:07.600,0:13:09.736 it's about control and regulation -- 0:13:09.760,0:13:13.656 keeping the physiological variables[br]within the tight bounds 0:13:13.680,0:13:15.520 that are compatible with survival. 0:13:16.640,0:13:19.496 When the brain uses predictions[br]to figure out what's there, 0:13:19.520,0:13:22.616 we perceive objects[br]as the causes of sensations. 0:13:22.640,0:13:26.256 When the brain uses predictions[br]to control and regulate things, 0:13:26.280,0:13:29.440 we experience how well[br]or how badly that control is going. 0:13:29.880,0:13:32.696 So our most basic experiences[br]of being a self, 0:13:32.720,0:13:34.776 of being an embodied organism, 0:13:34.800,0:13:38.760 are deeply grounded in the biological[br]mechanisms that keep us alive. 0:13:40.760,0:13:43.096 And when we follow this idea[br]all the way through, 0:13:43.120,0:13:46.816 we can start to see[br]that all of our conscious experiences, 0:13:46.840,0:13:51.576 since they all depend on the same[br]mechanisms of predictive perception, 0:13:51.600,0:13:55.016 all stem from this basic[br]drive to stay alive. 0:13:55.040,0:13:57.656 We experience the world and ourselves 0:13:57.680,0:14:00.760 with, through and because of[br]our living bodies. 0:14:01.560,0:14:03.960 Let me bring things together step-by-step. 0:14:04.560,0:14:06.136 What we consciously see depends 0:14:06.160,0:14:08.456 on the brain's best guess[br]of what's out there. 0:14:08.480,0:14:10.856 Our experienced world[br]comes from the inside out, 0:14:10.880,0:14:12.120 not just the outside in. 0:14:12.600,0:14:15.856 The rubber hand illusion shows[br]that this applies to our experiences 0:14:15.880,0:14:17.720 of what is and what is not our body. 0:14:18.560,0:14:22.136 And these self-related predictions[br]depend critically on sensory signals 0:14:22.160,0:14:23.920 coming from deep inside the body. 0:14:24.400,0:14:25.616 And finally, 0:14:25.640,0:14:30.016 experiences of being an embodied self[br]are more about control and regulation 0:14:30.040,0:14:31.720 than figuring out what's there. 0:14:32.840,0:14:36.056 So our experiences of the world[br]around us and ourselves within it -- 0:14:36.080,0:14:38.336 well, they're kinds[br]of controlled hallucinations 0:14:38.360,0:14:41.256 that have been shaped[br]over millions of years of evolution 0:14:41.280,0:14:44.040 to keep us alive in worlds[br]full of danger and opportunity. 0:14:44.480,0:14:47.160 We predict ourselves into existence. 0:14:48.520,0:14:51.000 Now, I leave you with three[br]implications of all this. 0:14:51.640,0:14:53.856 First, just as we can[br]misperceive the world, 0:14:53.880,0:14:55.656 we can misperceive ourselves 0:14:55.680,0:14:57.816 when the mechanisms[br]of prediction go wrong. 0:14:57.840,0:15:02.056 Understanding this opens many new[br]opportunities in psychiatry and neurology, 0:15:02.080,0:15:04.696 because we can finally[br]get at the mechanisms 0:15:04.720,0:15:06.616 rather than just treating the symptoms 0:15:06.640,0:15:09.160 in conditions like[br]depression and schizophrenia. 0:15:09.720,0:15:10.936 Second: 0:15:10.960,0:15:14.776 what it means to be me[br]cannot be reduced to or uploaded to 0:15:14.800,0:15:17.176 a software program running on a robot, 0:15:17.200,0:15:19.416 however smart or sophisticated. 0:15:19.440,0:15:22.056 We are biological, flesh-and-blood animals 0:15:22.080,0:15:25.336 whose conscious experiences[br]are shaped at all levels 0:15:25.360,0:15:28.336 by the biological mechanisms[br]that keep us alive. 0:15:28.360,0:15:32.000 Just making computers smarter[br]is not going to make them sentient. 0:15:33.000,0:15:34.296 Finally, 0:15:34.320,0:15:36.296 our own individual inner universe, 0:15:36.320,0:15:37.976 our way of being conscious, 0:15:38.000,0:15:40.760 is just one possible[br]way of being conscious. 0:15:41.840,0:15:43.816 And even human consciousness generally -- 0:15:43.840,0:15:47.816 it's just a tiny region in a vast space[br]of possible consciousnesses. 0:15:47.840,0:15:51.496 Our individual self and worlds[br]are unique to each of us, 0:15:51.520,0:15:54.736 but they're all grounded[br]in biological mechanisms 0:15:54.760,0:15:57.360 shared with many other living creatures. 0:15:57.920,0:16:00.880 Now, these are fundamental changes 0:16:01.760,0:16:04.016 in how we understand ourselves, 0:16:04.040,0:16:05.896 but I think they should be celebrated, 0:16:05.920,0:16:08.296 because as so often in science,[br]from Copernicus -- 0:16:08.320,0:16:10.320 we're not at the center of the universe -- 0:16:10.344,0:16:11.576 to Darwin -- 0:16:11.600,0:16:13.816 we're related to all other creatures -- 0:16:13.840,0:16:15.040 to the present day. 0:16:16.320,0:16:19.056 With a greater sense of understanding 0:16:19.080,0:16:21.496 comes a greater sense of wonder, 0:16:21.520,0:16:23.376 and a greater realization 0:16:23.400,0:16:28.000 that we are part of[br]and not apart from the rest of nature. 0:16:28.920,0:16:30.120 And ... 0:16:30.720,0:16:33.096 when the end of consciousness comes, 0:16:33.120,0:16:35.920 there's nothing to be afraid of. 0:16:36.560,0:16:37.760 Nothing at all. 0:16:38.480,0:16:39.696 Thank you. 0:16:39.720,0:16:47.746 (Applause)