WEBVTT 00:00:01.667 --> 00:00:05.229 I started life as a fashion designer, 00:00:05.253 --> 00:00:09.486 working closely with textile designers and fabric suppliers. 00:00:10.458 --> 00:00:15.323 But today, I can no longer see or talk to my new collaborators, 00:00:15.347 --> 00:00:18.434 because they're in the soil beneath our feet, 00:00:18.458 --> 00:00:20.846 on the shelves of our supermarkets 00:00:20.870 --> 00:00:23.813 and in the beer I'm going to drink when I finish this talk. 00:00:25.720 --> 00:00:28.299 I'm talking about microbes 00:00:28.323 --> 00:00:30.662 and designing with life. NOTE Paragraph 00:00:31.958 --> 00:00:33.149 Fifteen years ago, 00:00:33.173 --> 00:00:36.379 I completely changed both what I worked with 00:00:36.403 --> 00:00:37.569 and how I worked, 00:00:37.593 --> 00:00:41.061 after a revelatory collaboration with a biologist. 00:00:41.775 --> 00:00:46.664 Our project gave me a different perspective on life, 00:00:46.688 --> 00:00:49.811 introducing a whole new world of possibility 00:00:49.835 --> 00:00:52.958 around how we can design and make things. 00:00:53.561 --> 00:00:57.378 I discovered a radical manufacturing proposition: 00:00:58.323 --> 00:00:59.679 biofabrication. 00:01:00.172 --> 00:01:04.251 Literally, fabricating with biology. NOTE Paragraph 00:01:05.212 --> 00:01:06.632 What does that mean? 00:01:06.656 --> 00:01:11.871 Well, instead of processing plants, animals or oil 00:01:11.895 --> 00:01:14.347 to make consumer materials, 00:01:14.371 --> 00:01:19.991 we might grow materials directly with living organisms. 00:01:20.618 --> 00:01:24.634 In what many are terming "the Fourth Industrial Revolution," 00:01:24.658 --> 00:01:29.178 we're thinking about the new factories as being living cells. 00:01:29.568 --> 00:01:33.504 Bacteria, algae, fungi, yeast: 00:01:33.528 --> 00:01:38.710 our latest design tools include those of biotechnology. NOTE Paragraph 00:01:39.212 --> 00:01:41.887 My own journey in biofabrication 00:01:41.911 --> 00:01:44.644 started with a project called "Biocouture." 00:01:45.522 --> 00:01:49.857 The provocation was that instead of growing a plant, like cotton, 00:01:49.881 --> 00:01:52.174 in a field over several months, 00:01:52.198 --> 00:01:58.481 we could use microbes to grow a similar cellulose material in a lab 00:01:58.505 --> 00:01:59.934 in a few days. 00:01:59.958 --> 00:02:04.577 Using a certain species of bacteria in a nutrient-rich liquid, 00:02:04.601 --> 00:02:07.982 we fermented threads of cellulose 00:02:08.006 --> 00:02:12.188 that self-organized into a sheet of fabric. 00:02:12.529 --> 00:02:15.474 I dried the fabric I had grown 00:02:15.498 --> 00:02:21.110 and cut and sewed it into a range of garments, shoes and bags. 00:02:21.134 --> 00:02:24.373 In other words, in one lab we grew materials 00:02:24.397 --> 00:02:26.761 and turned them into a range of products 00:02:26.785 --> 00:02:28.745 in a matter of days. 00:02:28.769 --> 00:02:33.292 And this is in contrast to currents methods of fabric production, 00:02:33.316 --> 00:02:35.808 where a plant is grown, 00:02:35.832 --> 00:02:38.927 just the cotton part is harvested, 00:02:38.951 --> 00:02:40.736 processed into a yarn, 00:02:40.760 --> 00:02:42.529 woven into a fabric 00:02:42.553 --> 00:02:45.307 and then potentially shipped across oceans 00:02:45.331 --> 00:02:48.482 before being cut and sewn into a garment. 00:02:48.506 --> 00:02:51.125 All of that can take months. NOTE Paragraph 00:02:52.016 --> 00:02:55.112 So these prototypes indicated a field 00:02:55.136 --> 00:02:58.548 offering significant resource efficiencies. 00:02:58.572 --> 00:03:02.537 From reducing the water, energy and chemistry needed 00:03:02.561 --> 00:03:04.925 in the production of a material, 00:03:04.949 --> 00:03:08.339 through to generating zero waste, 00:03:08.363 --> 00:03:11.926 we grew fabrics to finished form -- 00:03:11.950 --> 00:03:16.803 if you like, "biological additive manufacture." NOTE Paragraph 00:03:17.307 --> 00:03:19.974 Through biofabrication, 00:03:19.998 --> 00:03:24.299 I had replaced many intensive man-made steps 00:03:24.323 --> 00:03:26.738 with one biological step. 00:03:27.433 --> 00:03:30.155 And as I engaged with this living system, 00:03:30.179 --> 00:03:32.446 it transformed my design thinking. 00:03:32.973 --> 00:03:37.234 Here was biology, with no intervention from me 00:03:37.258 --> 00:03:41.615 other than designing initial conditions for growth, 00:03:41.639 --> 00:03:45.660 efficiently producing a useful, sustainable material. 00:03:46.996 --> 00:03:53.782 So now I can't help but see all materials through the lens of biofabrication. NOTE Paragraph 00:03:53.806 --> 00:03:59.300 In fact, there's a growing global community of innovators 00:03:59.324 --> 00:04:02.887 rethinking materials with biology. 00:04:03.498 --> 00:04:08.283 Multiple companies are now growing mushroom materials, 00:04:08.307 --> 00:04:10.236 but not literally mushrooms -- 00:04:10.260 --> 00:04:15.371 using mycelium, which is the root system of fungi, 00:04:15.395 --> 00:04:19.177 to bind together agricultural byproducts. 00:04:19.201 --> 00:04:23.322 It's a process that's been described as "nature's glue." 00:04:23.680 --> 00:04:27.355 A common way to do this is to take a 3-D mold, 00:04:27.379 --> 00:04:32.831 fill it with a waste crop like corn stalks or hemp, 00:04:32.855 --> 00:04:34.450 add water, 00:04:34.474 --> 00:04:38.553 wait a few days for the mycelium to grow throughout, 00:04:38.577 --> 00:04:40.029 remove the mold, 00:04:40.053 --> 00:04:43.327 and you're left with a grown 3-D form. NOTE Paragraph 00:04:44.601 --> 00:04:48.268 Incredibly, we can grow all kinds of structures 00:04:48.292 --> 00:04:50.688 using living organisms, 00:04:50.712 --> 00:04:54.920 from foams that can replace plastics in footwear, 00:04:54.944 --> 00:04:57.833 to leather-like materials without animals. 00:04:57.857 --> 00:05:01.730 Furniture, flooring -- all are currently being prototyped. 00:05:01.754 --> 00:05:07.472 Fungi are able to grow materials that are naturally fire retardant, 00:05:07.496 --> 00:05:09.336 without any chemicals. 00:05:09.638 --> 00:05:11.368 They're naturally hydrophobic, 00:05:11.392 --> 00:05:13.622 meaning they won't absorb water. 00:05:13.646 --> 00:05:17.107 They have higher melt temperatures than plastics. 00:05:18.357 --> 00:05:22.801 Polystyrene can take thousands of years to degrade. 00:05:23.722 --> 00:05:26.252 Mushroom packaging materials 00:05:26.276 --> 00:05:29.950 can be naturally composted in your back garden, 00:05:29.974 --> 00:05:32.442 in as little as 30 days. NOTE Paragraph 00:05:33.442 --> 00:05:36.387 Living organisms are transforming waste 00:05:36.411 --> 00:05:40.879 into cost-competitive, performance-matching materials 00:05:40.903 --> 00:05:43.167 that can start to replace plastics 00:05:43.191 --> 00:05:46.319 and other CO2-emitting materials. 00:05:46.924 --> 00:05:50.543 And once we start growing materials with living organisms, 00:05:50.567 --> 00:05:56.212 it starts to make previous methods of manufacture seem illogical. NOTE Paragraph 00:05:57.300 --> 00:05:59.451 Take the humble house brick. 00:06:01.007 --> 00:06:04.053 The cement industry generates around eight percent 00:06:04.077 --> 00:06:05.942 of global CO2 emissions. 00:06:05.966 --> 00:06:09.355 That's more than all the planes and ships each year. 00:06:09.958 --> 00:06:15.287 The cement process requires materials to be fired in a kiln 00:06:15.311 --> 00:06:18.506 at over 2,000 degrees Fahrenheit. 00:06:19.504 --> 00:06:22.632 Compare this to bioMASON. 00:06:23.195 --> 00:06:27.767 They use a soil microbe to transform loose aggregates, 00:06:27.791 --> 00:06:30.409 like sand or crushed stone, 00:06:30.433 --> 00:06:34.712 into a biofabricated, or biocement, brick. 00:06:35.028 --> 00:06:38.782 Their process happens at room temperature, 00:06:38.806 --> 00:06:40.837 in just a couple of days. 00:06:40.861 --> 00:06:43.765 Think hydroponics for bricks. 00:06:43.789 --> 00:06:48.739 An irrigation system feeds nutrient-rich water 00:06:48.763 --> 00:06:50.660 to trays of bricks 00:06:50.684 --> 00:06:53.353 that have been inoculated with bacteria. 00:06:53.926 --> 00:06:56.260 The bacteria produce crystals 00:06:56.284 --> 00:06:59.346 that form around each grain of sand, 00:06:59.370 --> 00:07:02.553 locking together all the loose particles 00:07:02.577 --> 00:07:04.402 to form a solid brick. 00:07:05.725 --> 00:07:09.074 We can now grow construction materials 00:07:09.098 --> 00:07:11.613 in the elegant way nature does, 00:07:11.637 --> 00:07:13.716 just like a coral reef. 00:07:14.831 --> 00:07:20.434 And these biofabricated bricks are nearly three times stronger 00:07:20.458 --> 00:07:22.508 than a concrete block. 00:07:23.702 --> 00:07:27.797 And in stark contrast to traditional cement production, 00:07:27.821 --> 00:07:30.354 they store more carbon than they make. 00:07:31.202 --> 00:07:35.908 So if we could replace the 1.2 trillion fired bricks 00:07:35.932 --> 00:07:37.607 that are made each year 00:07:37.631 --> 00:07:40.297 with biofabricated bricks, 00:07:40.321 --> 00:07:42.934 we could reduce CO2 emissions 00:07:42.958 --> 00:07:46.762 by 800 million tons every year. NOTE Paragraph 00:07:48.307 --> 00:07:54.747 (Applause) NOTE Paragraph 00:07:56.034 --> 00:07:59.533 Beyond growing materials with living organisms, 00:07:59.557 --> 00:08:01.938 we're even starting to design products 00:08:01.962 --> 00:08:03.829 that encourage their growth. 00:08:04.338 --> 00:08:06.687 And this comes from the realization 00:08:06.711 --> 00:08:12.211 that the very thing we've been trying to marginalize -- life -- 00:08:12.235 --> 00:08:16.125 might actually be our greatest collaborator. 00:08:16.689 --> 00:08:20.538 To that end, we've been exploring all the ways 00:08:20.562 --> 00:08:24.640 that we can grow healthy microbes in our own ecosystems. 00:08:25.482 --> 00:08:29.713 A great example of this is architects 00:08:29.737 --> 00:08:33.499 who are imagining the skin of a building 00:08:33.523 --> 00:08:36.324 to function like the bark of a tree. 00:08:36.680 --> 00:08:39.627 But not as a cosmetic green layer. 00:08:39.982 --> 00:08:43.252 They're designing architectural barks 00:08:43.276 --> 00:08:47.262 as hosts for evolving ecologies. 00:08:48.104 --> 00:08:53.730 These surface structures are designed to invite life in. 00:08:54.239 --> 00:08:59.649 And if we applied the same energy we currently do suppressing forms of life 00:08:59.673 --> 00:09:02.649 towards cultivating life, 00:09:02.673 --> 00:09:06.400 we'd turn the negative image of the urban jungle 00:09:06.424 --> 00:09:11.940 into one that literally embodies a thriving, living ecosystem. 00:09:12.734 --> 00:09:18.656 By actively encouraging surface interactions with healthy microbes, 00:09:18.680 --> 00:09:21.688 we could improve passive climate control, 00:09:21.712 --> 00:09:23.545 stormwater management, 00:09:23.569 --> 00:09:25.704 and even reduce CO2 emissions 00:09:25.728 --> 00:09:29.743 by lowering the energy used to heat or cool our buildings. NOTE Paragraph 00:09:30.847 --> 00:09:34.943 We're just beginning to realize the potential 00:09:34.967 --> 00:09:38.117 of nature-based technologies. 00:09:38.141 --> 00:09:43.164 I'm excited that we're starting to design and biofabricate 00:09:43.188 --> 00:09:45.442 a new material world. NOTE Paragraph 00:09:49.177 --> 00:09:53.438 It's one that moves away from the exploitation 00:09:53.462 --> 00:09:55.915 of nonrenewable resources 00:09:55.939 --> 00:10:00.275 to working with the original, renewable life. 00:10:00.819 --> 00:10:02.871 Instead of designing out life, 00:10:02.895 --> 00:10:06.259 we're designing with it and for it. 00:10:06.934 --> 00:10:10.968 Packaging, fashion, footwear, furniture, construction -- 00:10:10.992 --> 00:10:16.143 biofabricated products can be grown close to centers of demand, 00:10:16.167 --> 00:10:19.937 with local resources, less land, energy, 00:10:19.961 --> 00:10:23.837 and even harnessing industrial waste streams. NOTE Paragraph 00:10:24.924 --> 00:10:28.925 It used to be that the tools of biotechnology 00:10:28.949 --> 00:10:31.316 were the preserve of powerful, 00:10:31.340 --> 00:10:35.528 multinational chemical and biotech companies. 00:10:35.950 --> 00:10:40.061 In the last century, we expected material innovation 00:10:40.085 --> 00:10:44.593 to come from the likes of DuPont, Dow, BASF. 00:10:45.173 --> 00:10:51.180 But this 21st-century material revolution is being led by start-ups 00:10:51.204 --> 00:10:54.347 with small teams and limited capital. 00:10:54.903 --> 00:10:58.617 And by the way, not all their founders have science degrees. 00:10:58.950 --> 00:11:03.363 They include artists, architects and designers. 00:11:04.538 --> 00:11:08.292 Over a billion dollars has already been invested 00:11:08.316 --> 00:11:12.260 in start-ups biofabricating consumer products. NOTE Paragraph 00:11:13.316 --> 00:11:17.763 I don't think we have a choice but to biofabricate our future. 00:11:18.938 --> 00:11:20.422 From the jacket you're wearing 00:11:20.446 --> 00:11:22.002 to the chair you're sitting in 00:11:22.026 --> 00:11:23.748 to the home you live in, 00:11:23.772 --> 00:11:29.355 your designed material world shouldn't compromise your health 00:11:29.379 --> 00:11:31.251 or that of our planet. 00:11:31.879 --> 00:11:33.879 If materials can't be recycled 00:11:33.903 --> 00:11:36.442 or naturally composted at home, 00:11:36.466 --> 00:11:37.974 we should reject them. NOTE Paragraph 00:11:37.998 --> 00:11:42.537 I'm committed to making this future a reality 00:11:42.561 --> 00:11:46.203 by shining a light on all the amazing work 00:11:46.227 --> 00:11:47.759 being done today 00:11:47.783 --> 00:11:50.791 and by facilitating more interactions 00:11:50.815 --> 00:11:55.255 between designers, scientists, investors and brands. 00:11:55.581 --> 00:11:58.747 Because we need a material revolution, 00:11:58.771 --> 00:12:00.397 and we need it now. NOTE Paragraph 00:12:00.914 --> 00:12:02.088 Thank you. NOTE Paragraph 00:12:02.112 --> 00:12:06.577 (Applause)