WEBVTT 99:59:59.999 --> 99:59:59.999 ♪ (music) ♪ 99:59:59.999 --> 99:59:59.999 (narrator) These days, you hear music all the time. 99:59:59.999 --> 99:59:59.999 It wakes us up, motivates our workouts, 99:59:59.999 --> 99:59:59.999 keeps us company on our commutes. 99:59:59.999 --> 99:59:59.999 It doesn't matter what kind of music it is, 99:59:59.999 --> 99:59:59.999 music itself has the ability to affect our moods and our bodies 99:59:59.999 --> 99:59:59.999 in all sorts of ways. 99:59:59.999 --> 99:59:59.999 We nod our heads, we sway, dance. 99:59:59.999 --> 99:59:59.999 Music can give us chills, 99:59:59.999 --> 99:59:59.999 even make us cry. 99:59:59.999 --> 99:59:59.999 Music activates every area of the brain that we have so far mapped. 99:59:59.999 --> 99:59:59.999 In fact, there's no area of the brain we know about 99:59:59.999 --> 99:59:59.999 that music doesn't touch in some way. 99:59:59.999 --> 99:59:59.999 But what's behind all that? 99:59:59.999 --> 99:59:59.999 What exactly does music do to us? 99:59:59.999 --> 99:59:59.999 To find out, I went to a whole series of tests 99:59:59.999 --> 99:59:59.999 designed to measure my responses to music. 99:59:59.999 --> 99:59:59.999 I met some kids whose brains may actually be changing, 99:59:59.999 --> 99:59:59.999 thanks to those hours of learning, practice, and performing. 99:59:59.999 --> 99:59:59.999 I spoke with a therapist who used music 99:59:59.999 --> 99:59:59.999 to help former congresswoman Gabrielle Giffords 99:59:59.999 --> 99:59:59.999 learn to speak again, 99:59:59.999 --> 99:59:59.999 and got a glimpse inside the brain 99:59:59.999 --> 99:59:59.999 of a two-time winning artist while he played... 99:59:59.999 --> 99:59:59.999 ( ) 99:59:59.999 --> 99:59:59.999 ...all to find out how music affects us. 99:59:59.999 --> 99:59:59.999 ♪ (music) ♪ 99:59:59.999 --> 99:59:59.999 So what's going on when we listen to music? 99:59:59.999 --> 99:59:59.999 We visited the USC Brain and Creativity Institute, 99:59:59.999 --> 99:59:59.999 where I had my head examined, literally, 99:59:59.999 --> 99:59:59.999 to try to figure it out. 99:59:59.999 --> 99:59:59.999 I'm going to go into this [FMRI] machine, 99:59:59.999 --> 99:59:59.999 a tiny tube will surround me. 99:59:59.999 --> 99:59:59.999 We'll get a baseline reading of my brain, 99:59:59.999 --> 99:59:59.999 and then I'm going to listen to some music. 99:59:59.999 --> 99:59:59.999 We're going to see how my brain responds. 99:59:59.999 --> 99:59:59.999 Just close your eyes, relax, 99:59:59.999 --> 99:59:59.999 and try and get into the music as best you can, okay? 99:59:59.999 --> 99:59:59.999 ♪ (music) ♪ 99:59:59.999 --> 99:59:59.999 And here's what we saw. 99:59:59.999 --> 99:59:59.999 These are scans of my brain. 99:59:59.999 --> 99:59:59.999 The areas in red are where my activity is above average; 99:59:59.999 --> 99:59:59.999 in blue, below average. 99:59:59.999 --> 99:59:59.999 As you can see, there is red activity all over my brain, 99:59:59.999 --> 99:59:59.999 not just in one specific area. 99:59:59.999 --> 99:59:59.999 Twenty-five years ago, 99:59:59.999 --> 99:59:59.999 the idea was that language is on the left side of the brain 99:59:59.999 --> 99:59:59.999 and music is in the right side of the brain. 99:59:59.999 --> 99:59:59.999 But now that we've got better quality tools, 99:59:59.999 --> 99:59:59.999 higher resolution neuro-imaging and better experimental methods, 99:59:59.999 --> 99:59:59.999 we've discovered that's not at all right. 99:59:59.999 --> 99:59:59.999 How does that play out in different regions of the brain? 99:59:59.999 --> 99:59:59.999 When music enters and then gets shuttled off 99:59:59.999 --> 99:59:59.999 to different parts of the brain, 99:59:59.999 --> 99:59:59.999 it stops at specialized processing units in auditory cortex, 99:59:59.999 --> 99:59:59.999 they track loudness and pitch and rhythm 99:59:59.999 --> 99:59:59.999 and [tambour] and things like that. 99:59:59.999 --> 99:59:59.999 There's visual cortex activation when you're reading music as a musician 99:59:59.999 --> 99:59:59.999 or watching music, 99:59:59.999 --> 99:59:59.999 motor cortex when you're tapping your feet, 99:59:59.999 --> 99:59:59.999 snapping your fingers, clapping you hands; 99:59:59.999 --> 99:59:59.999 and cerebellum which mediates the emotional responses; 99:59:59.999 --> 99:59:59.999 the memory and the hippocampus, 99:59:59.999 --> 99:59:59.999 hearing a familiar passage, 99:59:59.999 --> 99:59:59.999 finding it somewhere in your memory banks. 99:59:59.999 --> 99:59:59.999 Music is going on in both halves of your brain, 99:59:59.999 --> 99:59:59.999 the left and the right, 99:59:59.999 --> 99:59:59.999 the front and the back, 99:59:59.999 --> 99:59:59.999 the inside and the outside. 99:59:59.999 --> 99:59:59.999 ♪ (music) ♪ 99:59:59.999 --> 99:59:59.999 So what about a musicians's brain? 99:59:59.999 --> 99:59:59.999 To play a piece of music engages so many things: 99:59:59.999 --> 99:59:59.999 motor systems, timing systems, 99:59:59.999 --> 99:59:59.999 memory systems, hearing systems. 99:59:59.999 --> 99:59:59.999 There's all sorts of brain activity happening. 99:59:59.999 --> 99:59:59.999 It's a very robust thing to play music. 99:59:59.999 --> 99:59:59.999 ♪ (music) ♪ 99:59:59.999 --> 99:59:59.999 I'm Alex Jacob Robertson. 99:59:59.999 --> 99:59:59.999 I'm Nathan Glenn Robertson. 99:59:59.999 --> 99:59:59.999 We asked these 11-year old musicians 99:59:59.999 --> 99:59:59.999 to tell us what's going through their minds when they play. 99:59:59.999 --> 99:59:59.999 Some of the most important things are I think good postures, 99:59:59.999 --> 99:59:59.999 getting the note right, 99:59:59.999 --> 99:59:59.999 legato, staccato. 99:59:59.999 --> 99:59:59.999 (violin) 99:59:59.999 --> 99:59:59.999 For the violin, you need to hold your hand at the right place, 99:59:59.999 --> 99:59:59.999 and you need to be in tune, 99:59:59.999 --> 99:59:59.999 and then you also have to have not only the right intonation 99:59:59.999 --> 99:59:59.999 but the right sound, 99:59:59.999 --> 99:59:59.999 and then you also need to have great vibrato. 99:59:59.999 --> 99:59:59.999 There's lot of things to think about. 99:59:59.999 --> 99:59:59.999 (violin) 99:59:59.999 --> 99:59:59.999 (narrator) Back at USC, 99:59:59.999 --> 99:59:59.999 researchers have been studying kids who play music over the past five years 99:59:59.999 --> 99:59:59.999 to see how it affects their development. 99:59:59.999 --> 99:59:59.999 The multi-tasking areas of their brains understandable lit up, 99:59:59.999 --> 99:59:59.999 but they've seen other results too. 99:59:59.999 --> 99:59:59.999 Music training over the course of five years 99:59:59.999 --> 99:59:59.999 has had benefits in cognitive skills and decision making, 99:59:59.999 --> 99:59:59.999 also had some benefits in social behavior, 99:59:59.999 --> 99:59:59.999 and we've also seen changes in the associated brain structures. 99:59:59.999 --> 99:59:59.999 (narrator) Did you hear that? 99:59:59.999 --> 99:59:59.999 Changes in brain structures! 99:59:59.999 --> 99:59:59.999 They found that the brains of children who have studied music 99:59:59.999 --> 99:59:59.999 have stronger connections between the left and right hemispheres, 99:59:59.999 --> 99:59:59.999 and that can make them better, more creative problem solvers. 99:59:59.999 --> 99:59:59.999 And then there's emotion. 99:59:59.999 --> 99:59:59.999 (emotional music) 99:59:59.999 --> 99:59:59.999 When you hear a piece like this, 99:59:59.999 --> 99:59:59.999 it's easy to understand why emotions play such a big part in music. 99:59:59.999 --> 99:59:59.999 This song by Camille Saint-Saëns is known as the music for the dying swan in ballet. 99:59:59.999 --> 99:59:59.999 While it might move ballerinas to dance, it inspires different reactions in others. 99:59:59.999 --> 99:59:59.999 ( ) 99:59:59.999 --> 99:59:59.999 Some people get goosebumps, chills. 99:59:59.999 --> 99:59:59.999 That weird tingly sensation that you get 99:59:59.999 --> 99:59:59.999 when a great piece of music just hits you in the right way? 99:59:59.999 --> 99:59:59.999 It's called frisson, and not everyone gets it, 99:59:59.999 --> 99:59:59.999 but it turns out I do. 99:59:59.999 --> 99:59:59.999 Now we're going to have you listen to some pieces of music. 99:59:59.999 --> 99:59:59.999 Okay. 99:59:59.999 --> 99:59:59.999 When you experience a chill, if you do, 99:59:59.999 --> 99:59:59.999 I want you to just press this space bar 99:59:59.999 --> 99:59:59.999 so we have an indication 99:59:59.999 --> 99:59:59.999 of when those peak moments of enjoyment are happening. 99:59:59.999 --> 99:59:59.999 Okay. 99:59:59.999 --> 99:59:59.999 Matt Sachs, a PhD candidate at USC, 99:59:59.999 --> 99:59:59.999 wired me up to measure my physiological response. 99:59:59.999 --> 99:59:59.999 So when I'm feeling that emotional connection 99:59:59.999 --> 99:59:59.999 that has a physical manifestation, 99:59:59.999 --> 99:59:59.999 we'll see what my body is actually doing? 99:59:59.999 --> 99:59:59.999 Exactly. 99:59:59.999 --> 99:59:59.999 (dramatic music) 99:59:59.999 --> 99:59:59.999 Alright, how was that? 99:59:59.999 --> 99:59:59.999 That was-- that had a lot of them. 99:59:59.999 --> 99:59:59.999 We got them all. 99:59:59.999 --> 99:59:59.999 Now full disclosure: 99:59:59.999 --> 99:59:59.999 Back in the day, I played the cello, 99:59:59.999 --> 99:59:59.999 which might have something to do with why that particular song affected me. 99:59:59.999 --> 99:59:59.999 Nice hair! 99:59:59.999 --> 99:59:59.999 But it turns out the brain is at work here too. 99:59:59.999 --> 99:59:59.999 We processed the difference between this pathway 99:59:59.999 --> 99:59:59.999 that connects the auditory regions is on the side of the brain here, 99:59:59.999 --> 99:59:59.999 to the emotional regions, 99:59:59.999 --> 99:59:59.999 and we showed that the tract actually that connects those two regions 99:59:59.999 --> 99:59:59.999 is stronger, 99:59:59.999 --> 99:59:59.999 there's more fibers in that region in the people who get chills. 99:59:59.999 --> 99:59:59.999 (narrator) Which means that some people's brains 99:59:59.999 --> 99:59:59.999 might have better communication 99:59:59.999 --> 99:59:59.999 between what they hear and how they feel. 99:59:59.999 --> 99:59:59.999 The music itself also plays a role in frisson. 99:59:59.999 --> 99:59:59.999 Sachs uses different songs in his lectures to see if students get it. 99:59:59.999 --> 99:59:59.999 I'll say raise your hand when you get a chill 99:59:59.999 --> 99:59:59.999 and I'll play a piece of music, a classical piece, 99:59:59.999 --> 99:59:59.999 and maybe half the people will get it. 99:59:59.999 --> 99:59:59.999 (narrator) Then he plays this.. 99:59:59.999 --> 99:59:59.999 ( ) 99:59:59.999 --> 99:59:59.999 Rolling Stone's Give me Shelter. 99:59:59.999 --> 99:59:59.999 Have you ever seen the movie 20 Feet from Stardom? 99:59:59.999 --> 99:59:59.999 The documentary about back up singers? 99:59:59.999 --> 99:59:59.999 Yeah. 99:59:59.999 --> 99:59:59.999 There's a part where they isolate the vocals from Give me Shelter. 99:59:59.999 --> 99:59:59.999 ♪ ( ) ♪ 99:59:59.999 --> 99:59:59.999 And I play that, 99:59:59.999 --> 99:59:59.999 and 90% of the people experience chills, 99:59:59.999 --> 99:59:59.999 sort of independent of where I go. 99:59:59.999 --> 99:59:59.999 I have to tell you, bringing that up made me think about it 99:59:59.999 --> 99:59:59.999 and I got that little kind of thing at the back of my neck. 99:59:59.999 --> 99:59:59.999 (narrator) But why would that happen? 99:59:59.999 --> 99:59:59.999 The high pitched notes that she hit almost sounds like a scream 99:59:59.999 --> 99:59:59.999 and it's very important ancestrally for us 99:59:59.999 --> 99:59:59.999 to be able to pay attention to a scream, 99:59:59.999 --> 99:59:59.999 figure out what's going on, 99:59:59.999 --> 99:59:59.999 and either run or fight, whatever we need to do. 99:59:59.999 --> 99:59:59.999 (narrator) So how come that manifests as pleasure? 99:59:59.999 --> 99:59:59.999 Well it's because our pre-frontal cortex, 99:59:59.999 --> 99:59:59.999 the more rational, thinking part of the brain kicks in. 99:59:59.999 --> 99:59:59.999 So you realize very quickly, 99:59:59.999 --> 99:59:59.999 after you have this really quick startle reflex, 99:59:59.999 --> 99:59:59.999 that there's nothing actually threatening about the piece of music, 99:59:59.999 --> 99:59:59.999 that you're sitting in a safe space with your headphones on, 99:59:59.999 --> 99:59:59.999 and it's in that reappraisal 99:59:59.999 --> 99:59:59.999 that we tend to think of the pleasure responses emerging. 99:59:59.999 --> 99:59:59.999 And whether you find listening to music so pleasurable you get chills 99:59:59.999 --> 99:59:59.999 or you absolutely despise a song, 99:59:59.999 --> 99:59:59.999 it can produce absolutely fascinating effects in the brain. 99:59:59.999 --> 99:59:59.999 According to [Levitan], music we enjoy 99:59:59.999 --> 99:59:59.999 triggers the brain's internal opioid system-- 99:59:59.999 --> 99:59:59.999 yes, opioid system. 99:59:59.999 --> 99:59:59.999 And just like the opioids that come in pill form 99:59:59.999 --> 99:59:59.999 these chemicals make you feel good and help relieve pain. 99:59:59.999 --> 99:59:59.999 And music you don't like? Well, that releases cortisol, 99:59:59.999 --> 99:59:59.999 the notorious stress hormone. 99:59:59.999 --> 99:59:59.999 But that's not even the half of what music can do in the brain. 99:59:59.999 --> 99:59:59.999 Can you turn on the lights? 99:59:59.999 --> 99:59:59.999 (narrator) When former Congresswomen Gabrielle Giffords 99:59:59.999 --> 99:59:59.999 was shot in 2011 99:59:59.999 --> 99:59:59.999 the left side of her brain was severely damaged, 99:59:59.999 --> 99:59:59.999 leaving her struggling to speak, 99:59:59.999 --> 99:59:59.999 a condition called aphasia. 99:59:59.999 --> 99:59:59.999 Gabby, are you frustrated? 99:59:59.999 --> 99:59:59.999 (narrator) But to get an idea 99:59:59.999 --> 99:59:59.999 of just how powerful music's effect on the brain can be, 99:59:59.999 --> 99:59:59.999 watch this video. 99:59:59.999 --> 99:59:59.999 You ready? 99:59:59.999 --> 99:59:59.999 (together) This little light of mine I'm gonna let it shine. 99:59:59.999 --> 99:59:59.999 (narrator) That word that she'd been struggling to say, "light," 99:59:59.999 --> 99:59:59.999 came easily in song. 99:59:59.999 --> 99:59:59.999 Why would she be able to sing a word when she's unable to say it? 99:59:59.999 --> 99:59:59.999 What we know about the brain 99:59:59.999 --> 99:59:59.999 is that the left hemisphere controls language, 99:59:59.999 --> 99:59:59.999 and there are many other parts of the brain 99:59:59.999 --> 99:59:59.999 that have music access. 99:59:59.999 --> 99:59:59.999 Music therapist Maegan Morrow's job 99:59:59.999 --> 99:59:59.999 is to help patients use those other pathways to regain language. 99:59:59.999 --> 99:59:59.999 Sometimes I compare it to being in traffic, 99:59:59.999 --> 99:59:59.999 and you can't move any further, 99:59:59.999 --> 99:59:59.999 but you might need to exit and take the feeder road 99:59:59.999 --> 99:59:59.999 to get you to your destination. 99:59:59.999 --> 99:59:59.999 So music is basically like that feeder road 99:59:59.999 --> 99:59:59.999 to the new destination. 99:59:59.999 --> 99:59:59.999 (narrator) Like a detour. 99:59:59.999 --> 99:59:59.999 So we know that music can help us relearn things like speech 99:59:59.999 --> 99:59:59.999 by accessing alternative pathways in the brain 99:59:59.999 --> 99:59:59.999 and that learning to play music can help strengthen brain connections. 99:59:59.999 --> 99:59:59.999 But what about making music? 99:59:59.999 --> 99:59:59.999 To make music is like-- 99:59:59.999 --> 99:59:59.999 it's the language of humanity. 99:59:59.999 --> 99:59:59.999 No matter where I go in the world, 99:59:59.999 --> 99:59:59.999 if I'm playing something, 99:59:59.999 --> 99:59:59.999 it doesn't matter if someone can't speak the language-- 99:59:59.999 --> 99:59:59.999 if they're into it, they're into it. 99:59:59.999 --> 99:59:59.999 (narrator) This is Xavier Dphrepaulezz, better known as Fantastic Negrito. 99:59:59.999 --> 99:59:59.999 We brought him to UCSF to meet Charles Limb, 99:59:59.999 --> 99:59:59.999 a neuroscientist who studies musical creativity. 99:59:59.999 --> 99:59:59.999 The Duffler's up next. 99:59:59.999 --> 99:59:59.999 (narrator) To understand how Fantastic Negrito's brain works 99:59:59.999 --> 99:59:59.999 when making music, 99:59:59.999 --> 99:59:59.999 Dr. Limb had him play on of his songs while going through the fMRI. 99:59:59.999 --> 99:59:59.999 (Fantastic Negrito singing) 99:59:59.999 --> 99:59:59.999 (narrator) So how did his brain respond? 99:59:59.999 --> 99:59:59.999 The areas that process sensory and motor skills, along with sounds, 99:59:59.999 --> 99:59:59.999 lit up. 99:59:59.999 --> 99:59:59.999 You can see them here in red and yellow. 99:59:59.999 --> 99:59:59.999 Makes sense, right? 99:59:59.999 --> 99:59:59.999 But here's the really interesting part. 99:59:59.999 --> 99:59:59.999 Limb asked him to improvise 99:59:59.999 --> 99:59:59.999 to see what happens when he's creating something totally original. 99:59:59.999 --> 99:59:59.999 (Fantastic Negrito singing) 99:59:59.999 --> 99:59:59.999 Now watch what happens to his brain? 99:59:59.999 --> 99:59:59.999 Stop! 99:59:59.999 --> 99:59:59.999 (laughter) 99:59:59.999 --> 99:59:59.999 Now watch what happens to his brain. 99:59:59.999 --> 99:59:59.999 The areas that were active before, 99:59:59.999 --> 99:59:59.999 the ones that deal with motor skills and sounds, 99:59:59.999 --> 99:59:59.999 are even more active. 99:59:59.999 --> 99:59:59.999 But see how there's way more blue in the front of his brain? 99:59:59.999 --> 99:59:59.999 That's the pre-frontal cortex, 99:59:59.999 --> 99:59:59.999 and it's associated with effortful planning and conscience self-monitoring, 99:59:59.999 --> 99:59:59.999 and it's blue because it's less active. 99:59:59.999 --> 99:59:59.999 We see that the pre-frontal cortex 99:59:59.999 --> 99:59:59.999 appears to be really shutting down in these moments of high creativity, 99:59:59.999 --> 99:59:59.999 kind of like letting of of these conscious self-censoring or self-monitoring areas 99:59:59.999 --> 99:59:59.999 that normally are there to help control our output. 99:59:59.999 --> 99:59:59.999 (narrator) And Limb says it's about more than just letting go. 99:59:59.999 --> 99:59:59.999 You view it from a perspective of survival. 99:59:59.999 --> 99:59:59.999 If human beings only could do memorized route responses, 99:59:59.999 --> 99:59:59.999 we'd be long gone. 99:59:59.999 --> 99:59:59.999 It is not just the thing that happens in clubs and in jazz bars, 99:59:59.999 --> 99:59:59.999 it's actually maybe the most fundamental form 99:59:59.999 --> 99:59:59.999 of what it means to be human, 99:59:59.999 --> 99:59:59.999 to come up with new ideas. 99:59:59.999 --> 99:59:59.999 (singing) 99:59:59.999 --> 99:59:59.999 (narrator) So music is so much more than notes on a page. 99:59:59.999 --> 99:59:59.999 It can change the way we think and speak and feel. 99:59:59.999 --> 99:59:59.999 But is there a limit to what science can tell us about music? 99:59:59.999 --> 99:59:59.999 Just when I discovered the answer to one thing, 99:59:59.999 --> 99:59:59.999 five new questions pop up that are more interesting than the first, 99:59:59.999 --> 99:59:59.999 and I've gained an appreciation 99:59:59.999 --> 99:59:59.999 for how complex the music-making and music-listening system is. 99:59:59.999 --> 99:59:59.999 It's not demystified for me at all. 99:59:59.999 --> 99:59:59.999 It's more mysterious than ever. 99:59:59.999 --> 99:59:59.999 (singing) 99:59:59.999 --> 99:59:59.999 (applause)