WEBVTT 00:00:00.000 --> 00:00:00.610 00:00:00.610 --> 00:00:03.620 We could have a debate about what the most interesting cell 00:00:03.620 --> 00:00:07.540 in the human body is, but I think easily the neuron would 00:00:07.540 --> 00:00:10.810 make the top five, and it's not just because the cell 00:00:10.810 --> 00:00:11.830 itself is interesting. 00:00:11.830 --> 00:00:14.640 The fact that it essentially makes up our brain and our 00:00:14.640 --> 00:00:17.420 nervous system and is responsible for the thoughts 00:00:17.420 --> 00:00:22.010 and our feelings and maybe for all of our sentience, I think, 00:00:22.010 --> 00:00:24.625 would easily make it the top one or two cells. 00:00:24.625 --> 00:00:26.920 So what I want to do is first to show you what a neuron 00:00:26.920 --> 00:00:27.450 looks like. 00:00:27.450 --> 00:00:30.290 And, of course, this is kind of the perfect example. 00:00:30.290 --> 00:00:31.670 This isn't what all neurons look like. 00:00:31.670 --> 00:00:33.350 And then we're going to talk a little bit about how it 00:00:33.350 --> 00:00:37.000 performs its function, which is essentially communication, 00:00:37.000 --> 00:00:40.760 essentially transmitting signals across its length, 00:00:40.760 --> 00:00:43.400 depending on the signals it receives. 00:00:43.400 --> 00:00:45.470 So if I were to draw a neuron-- let me 00:00:45.470 --> 00:00:46.720 pick a better color. 00:00:46.720 --> 00:00:50.750 00:00:50.750 --> 00:00:52.060 So let's say I have a neuron. 00:00:52.060 --> 00:00:53.120 It looks something like this. 00:00:53.120 --> 00:00:57.780 So in the middle you have your soma and then from the soma-- 00:00:57.780 --> 00:01:00.850 let me draw the nucleus. 00:01:00.850 --> 00:01:03.390 This is a nucleus, just like any cell's nucleus. 00:01:03.390 --> 00:01:07.190 And then the soma's considered the body of the neuron and 00:01:07.190 --> 00:01:09.260 then the neuron has these little things sticking out 00:01:09.260 --> 00:01:13.680 from it that keep branching off. 00:01:13.680 --> 00:01:16.080 Maybe they look something like this. 00:01:16.080 --> 00:01:18.910 I don't want to spend too much time just drawing the neuron, 00:01:18.910 --> 00:01:23.700 but you've probably seen drawings like this before. 00:01:23.700 --> 00:01:27.810 And these branches off of the soma of the neuron, off of its 00:01:27.810 --> 00:01:32.010 body, these are called dendrites. 00:01:32.010 --> 00:01:34.455 They can keep splitting off like that. 00:01:34.455 --> 00:01:36.990 I want to do a fairly reasonable drawing so I'll 00:01:36.990 --> 00:01:39.040 spend a little time doing that. 00:01:39.040 --> 00:01:43.000 00:01:43.000 --> 00:01:46.140 So these right here, these are dendrites. 00:01:46.140 --> 00:01:48.500 And these tend to be-- and nothing is 00:01:48.500 --> 00:01:49.860 always the case in biology. 00:01:49.860 --> 00:01:53.160 Sometimes different parts of different cells perform other 00:01:53.160 --> 00:01:56.940 functions, but these tend to be where the neuron receives 00:01:56.940 --> 00:01:58.160 its signal. 00:01:58.160 --> 00:02:01.220 And we'll talk more about what it means to receive and 00:02:01.220 --> 00:02:03.370 transmit a signal in this video and 00:02:03.370 --> 00:02:04.940 probably in the next few. 00:02:04.940 --> 00:02:09.630 So this is where it receives the signal. 00:02:09.630 --> 00:02:11.160 So this is the dendrite. 00:02:11.160 --> 00:02:13.030 This right here is the soma. 00:02:13.030 --> 00:02:14.390 Soma means body. 00:02:14.390 --> 00:02:17.130 This is the body of the neuron. 00:02:17.130 --> 00:02:20.600 And then we have kind of a-- you can almost view it as a 00:02:20.600 --> 00:02:22.100 tail of the neuron. 00:02:22.100 --> 00:02:23.350 It's called the axon. 00:02:23.350 --> 00:02:26.330 00:02:26.330 --> 00:02:29.880 A neuron can be a reasonably normal sized cell, although 00:02:29.880 --> 00:02:32.820 there is a huge range, but the axons can be quite long. 00:02:32.820 --> 00:02:33.870 They could be short. 00:02:33.870 --> 00:02:36.520 Sometimes in the brain you might have very small axons, 00:02:36.520 --> 00:02:39.610 but you might have axons that go down the spinal column or 00:02:39.610 --> 00:02:42.190 that go along one of your limbs-- or if you're talking 00:02:42.190 --> 00:02:44.240 about one of a dinosaur's limbs. 00:02:44.240 --> 00:02:47.190 So the axon can actually stretch several feet. 00:02:47.190 --> 00:02:49.160 Not all neurons' axons are several feet, 00:02:49.160 --> 00:02:50.150 but they could be. 00:02:50.150 --> 00:02:53.760 And this is really where a lot of the distance of the signal 00:02:53.760 --> 00:02:55.100 gets traveled. 00:02:55.100 --> 00:02:58.190 Let me draw the axon. 00:02:58.190 --> 00:03:01.620 So the axon will look something like this. 00:03:01.620 --> 00:03:06.080 And at the end, it ends at the axon terminal where it can 00:03:06.080 --> 00:03:10.360 connect to other dendrites or maybe to other types of tissue 00:03:10.360 --> 00:03:13.990 or muscle if the point of this neuron is to tell a muscle to 00:03:13.990 --> 00:03:14.910 do something. 00:03:14.910 --> 00:03:16.810 So at the end of the axon, you have the axon 00:03:16.810 --> 00:03:19.070 terminal right there. 00:03:19.070 --> 00:03:22.170 I'll do my best to draw it like that. 00:03:22.170 --> 00:03:22.830 Let me label it. 00:03:22.830 --> 00:03:25.270 So this is the axon. 00:03:25.270 --> 00:03:26.530 This is the axon terminal. 00:03:26.530 --> 00:03:29.790 00:03:29.790 --> 00:03:33.090 And you'll sometimes hear the word-- the point at which the 00:03:33.090 --> 00:03:36.590 soma or the body of the neuron connects to the axon is as 00:03:36.590 --> 00:03:39.400 often referred to as the axon hillock-- maybe you can kind 00:03:39.400 --> 00:03:40.380 of view it as kind of a lump. 00:03:40.380 --> 00:03:41.690 It starts to form the axon. 00:03:41.690 --> 00:03:46.740 00:03:46.740 --> 00:03:54.610 And then we're going to talk about how the impulses travel. 00:03:54.610 --> 00:03:58.970 And a huge part in what allows them to travel efficiently are 00:03:58.970 --> 00:04:01.420 these insulating cells around the axon. 00:04:01.420 --> 00:04:04.760 00:04:04.760 --> 00:04:06.520 We're going to talk about this in detail and how they 00:04:06.520 --> 00:04:09.230 actually work, but it's good just to have the anatomical 00:04:09.230 --> 00:04:17.420 structure first. So these are called Schwann cells and 00:04:17.420 --> 00:04:20.450 they're covering-- they make up the myelin sheath. 00:04:20.450 --> 00:04:23.040 So this covering, this insulation, at different 00:04:23.040 --> 00:04:24.850 intervals around the axon, this is 00:04:24.850 --> 00:04:26.710 called the myelin sheath. 00:04:26.710 --> 00:04:29.540 So Schwann cells make up the myelin sheath. 00:04:29.540 --> 00:04:31.010 I'll do one more just like that. 00:04:31.010 --> 00:04:40.040 00:04:40.040 --> 00:04:42.780 And then these little spaces between the myelin sheath-- 00:04:42.780 --> 00:04:46.390 just so we have all of the terminology from-- so we know 00:04:46.390 --> 00:04:50.650 the entire anatomy of the neuron-- these are called the 00:04:50.650 --> 00:04:51.900 nodes of Ranvier. 00:04:51.900 --> 00:04:56.620 00:04:56.620 --> 00:04:57.950 I guess they're named after Ranvier. 00:04:57.950 --> 00:04:59.910 Maybe he was the guy who looked and saw they had these 00:04:59.910 --> 00:05:02.810 little slots here where you don't have myelin sheath. 00:05:02.810 --> 00:05:05.280 So these are the nodes of Ranvier. 00:05:05.280 --> 00:05:07.980 So the general idea, as I mentioned, is that you get a 00:05:07.980 --> 00:05:08.860 signal here. 00:05:08.860 --> 00:05:11.070 We're going to talk more about what the signal means-- and 00:05:11.070 --> 00:05:13.890 then that signal gets-- actually, the signals can be 00:05:13.890 --> 00:05:16.580 summed, so you might have one little signal right there, 00:05:16.580 --> 00:05:19.450 another signal right there, and then you'll have maybe a 00:05:19.450 --> 00:05:23.010 larger signal there and there-- and that the combined 00:05:23.010 --> 00:05:26.780 effects of these signals get summed up and they travel to 00:05:26.780 --> 00:05:30.430 the hillock and if they're a large enough, they're going to 00:05:30.430 --> 00:05:34.940 trigger an action potential on the axon, which will cause a 00:05:34.940 --> 00:05:38.280 signal to travel down the balance of the axon and then 00:05:38.280 --> 00:05:42.920 over here it might be connected via synapses to 00:05:42.920 --> 00:05:44.440 other dendrites or muscles. 00:05:44.440 --> 00:05:46.420 And we'll talk more about synapses and those might help 00:05:46.420 --> 00:05:47.790 trigger other things. 00:05:47.790 --> 00:05:49.770 So you're saying, what's triggering these things here? 00:05:49.770 --> 00:05:54.400 Well, this could be the terminal end of other neurons' 00:05:54.400 --> 00:05:57.100 axons, like in the brain. 00:05:57.100 --> 00:05:58.910 This could be some type of sensory neuron. 00:05:58.910 --> 00:06:02.490 This could be on a taste bud someplace, so a salt molecule 00:06:02.490 --> 00:06:06.280 somehow can trigger it or a sugar molecule-- or this might 00:06:06.280 --> 00:06:07.390 be some type of sensor. 00:06:07.390 --> 00:06:09.110 It could be a whole bunch of different things and we'll 00:06:09.110 --> 00:06:11.700 talk more about the different types of neurons. 00:06:11.700 --> 00:06:12.950