1 00:00:09,777 --> 00:00:12,887 Do you know what Aristotle believed? 2 00:00:13,987 --> 00:00:17,757 Aristotle said that we think with our hearts 3 00:00:17,757 --> 00:00:22,297 and the brain only cools the blood coming from our hearts 4 00:00:22,297 --> 00:00:23,757 after thinking. 5 00:00:24,432 --> 00:00:25,952 Doesn't it sound outrageous 6 00:00:25,952 --> 00:00:29,332 that one of the most brilliant minds in human history 7 00:00:29,332 --> 00:00:32,732 had paralleled the human brain to a radiator? 8 00:00:33,964 --> 00:00:40,121 I think we all agree that this time Aristotle was wrong. 9 00:00:41,282 --> 00:00:45,402 For about 10 years, I've been studying the heart-brain relationship. 10 00:00:46,229 --> 00:00:51,189 Basically, the way in which the heart induces neurological disease, 11 00:00:51,189 --> 00:00:54,579 like cerebral vascular accidents, 12 00:00:54,579 --> 00:00:57,959 and how the brain induces heart disease, 13 00:00:57,959 --> 00:00:59,709 like arrhythmias. 14 00:01:00,629 --> 00:01:05,239 And through this research I came across many surprises. 15 00:01:05,239 --> 00:01:09,617 That belief that we only think with our brain 16 00:01:09,617 --> 00:01:13,587 and that the heart only pumps blood, is not that accurate. 17 00:01:14,930 --> 00:01:19,540 For example, how many times you were told to "decide with your heart"? 18 00:01:20,489 --> 00:01:25,099 What does this pump of pure muscle have to do with decision-making? 19 00:01:25,099 --> 00:01:27,529 Or maybe with the intuition, 20 00:01:27,529 --> 00:01:30,279 which sometimes we need to make decisions? 21 00:01:31,335 --> 00:01:33,825 There is a study by Cambridge University 22 00:01:33,825 --> 00:01:37,895 that revolutionized the subject on deciding with our hearts. 23 00:01:37,895 --> 00:01:41,195 And opened the path to what we call: 24 00:01:41,195 --> 00:01:43,305 "research in decision-making." 25 00:01:44,258 --> 00:01:48,238 In this study, subjects were asked to participate in a game 26 00:01:48,238 --> 00:01:51,098 in which they had to make decisions 27 00:01:51,098 --> 00:01:54,668 based on simulated situations on a computer. 28 00:01:55,972 --> 00:02:00,102 There were always two options: 29 00:02:00,102 --> 00:02:03,742 one with a favorable outcome, 30 00:02:03,742 --> 00:02:06,252 the other with a unfavorable outcome. 31 00:02:07,195 --> 00:02:12,325 While participating in the game, they had their heart beats monitored 32 00:02:12,325 --> 00:02:18,085 in order to know how the heart reacted just before making a decision. 33 00:02:19,645 --> 00:02:22,375 And what they found was that 34 00:02:22,375 --> 00:02:26,185 before making a decision that would have a favorable outcome, 35 00:02:26,185 --> 00:02:28,655 the heart beat in a particular way. 36 00:02:29,496 --> 00:02:33,246 But when they were going to make a unfavorable decision, 37 00:02:33,246 --> 00:02:35,326 it beat in a totally different way. 38 00:02:36,005 --> 00:02:38,215 So, apparently, 39 00:02:38,215 --> 00:02:41,635 the heart knew before the brain was conscious, 40 00:02:41,635 --> 00:02:44,255 if the decision about to be taken 41 00:02:44,255 --> 00:02:46,445 was going to be favorable or unfavorable. 42 00:02:47,323 --> 00:02:50,633 I ask you to keep this in mind 43 00:02:50,633 --> 00:02:55,353 and we'll make an exercise ourselves, we'll experiment with our bodies. 44 00:02:56,193 --> 00:02:59,223 Please, close your eyes. 45 00:03:00,733 --> 00:03:04,033 Close your eyes and keep quiet, 46 00:03:04,033 --> 00:03:08,413 and put your hands over your knees, until I tell you so. 47 00:03:09,786 --> 00:03:12,816 While doing this test, 48 00:03:12,816 --> 00:03:17,466 I'd like to know if you can sense your heart beats. 49 00:03:24,286 --> 00:03:26,726 OK, please open your eyes. 50 00:03:27,756 --> 00:03:32,946 Please, raise your hands those of you who were able to sense your heart beats. 51 00:03:34,807 --> 00:03:37,467 Perfect, approximately 50 percent. 52 00:03:37,467 --> 00:03:40,617 Among those who raised their hands 53 00:03:40,617 --> 00:03:44,087 probably many of them have developed 54 00:03:44,087 --> 00:03:46,897 an ability called interoception. 55 00:03:48,513 --> 00:03:50,123 What is the interoception? 56 00:03:50,123 --> 00:03:54,633 It's the capacity of sensing the messages produced by our bodies, 57 00:03:54,633 --> 00:03:56,223 sent by our bodies. 58 00:03:56,223 --> 00:03:58,973 For example, in this case, our heart beats. 59 00:03:59,976 --> 00:04:02,866 Back to the experiment carried out at Cambridge University, 60 00:04:02,866 --> 00:04:07,906 those participating in the game had done what you have 61 00:04:07,906 --> 00:04:12,286 and were classified in those with good interoception, 62 00:04:12,286 --> 00:04:14,196 and those with bad interoception. 63 00:04:14,911 --> 00:04:17,551 The most interesting fact in this experiment was that 64 00:04:17,551 --> 00:04:22,651 those with good interoception made favorable decisions more frequently 65 00:04:22,651 --> 00:04:24,711 than those without good interoception. 66 00:04:25,835 --> 00:04:31,465 The conclusion of this seems to be that those people able to detect, 67 00:04:31,465 --> 00:04:37,655 decode and process messages sent by our hearts before making a decision, 68 00:04:37,655 --> 00:04:41,235 apparently can make better decisions. 69 00:04:41,235 --> 00:04:44,955 Like in any other revolutionary experiment like this one, 70 00:04:44,955 --> 00:04:49,295 it's necessary to check results with other scientists making similar studies. 71 00:04:49,295 --> 00:04:52,965 But, meanwhile, don't you think that sayings like: 72 00:04:52,965 --> 00:04:56,025 "listen to your heart" or "I have gut feeling" 73 00:04:56,025 --> 00:04:58,475 don't sound so wrong when deciding? 74 00:04:59,195 --> 00:05:03,635 But how do brain and heart collaborate in such manner 75 00:05:03,635 --> 00:05:05,665 when making a decision? 76 00:05:06,330 --> 00:05:11,530 There's a specific area inside the brain, the main subject of our research, 77 00:05:11,533 --> 00:05:13,533 called insula. 78 00:05:13,533 --> 00:05:17,673 It's called insula because it resembles an island underneath the cortex, 79 00:05:17,673 --> 00:05:22,143 and is hidden, and extremely connected to the whole brain. 80 00:05:22,143 --> 00:05:25,723 It resembles a local airport 81 00:05:25,723 --> 00:05:28,733 where all connections arrive to and depart from. 82 00:05:29,645 --> 00:05:33,325 But the insula is also connected to other organs 83 00:05:33,325 --> 00:05:36,465 like the heart or the bowel, among others, 84 00:05:36,465 --> 00:05:39,305 and so, it is also an international airport 85 00:05:39,305 --> 00:05:42,535 where all connections to other organs 86 00:05:42,735 --> 00:05:46,560 besides the brain come to and depart from. 87 00:05:46,560 --> 00:05:50,560 Most interestingly about the insula is that it's made purely of neurons, 88 00:05:50,560 --> 00:05:53,060 and the heart is pure muscle. 89 00:05:53,060 --> 00:05:54,770 So you may say: 90 00:05:54,770 --> 00:05:58,850 How can these two organs communicate being so different? 91 00:05:59,830 --> 00:06:05,930 The answer is quite surprising because the heart, like the brain, 92 00:06:05,930 --> 00:06:07,260 has neurons. 93 00:06:08,543 --> 00:06:12,193 Those white spots you see there in the heart are neurons, 94 00:06:12,193 --> 00:06:15,713 group of neurons, where connections from the brain arrive to. 95 00:06:16,562 --> 00:06:19,572 And this you are seeing is a typical heart; 96 00:06:19,572 --> 00:06:20,982 the heart's anatomy. 97 00:06:20,982 --> 00:06:25,782 And what happened throughout human history for a heart like that 98 00:06:25,782 --> 00:06:29,642 to become the universal symbol of love? 99 00:06:30,323 --> 00:06:33,663 What does the heart have to do with loving or falling in love? 100 00:06:35,533 --> 00:06:38,733 In other study, 101 00:06:38,733 --> 00:06:42,933 subjects were asked to bring pictures of someone they loved deeply, 102 00:06:42,933 --> 00:06:46,563 and somebody who didn't mean anything to them. 103 00:06:46,563 --> 00:06:50,153 They used a special kind of magnetic resonance imaging, called "functional," 104 00:06:50,153 --> 00:06:54,543 that let us see which parts of the brain are being activated 105 00:06:54,543 --> 00:06:57,603 after certain stimuli, or certain actions. 106 00:06:58,790 --> 00:07:00,840 What came out from this experiment is that 107 00:07:00,840 --> 00:07:04,500 when subjects saw the picture of their loved ones, 108 00:07:04,500 --> 00:07:10,360 areas related with pleasure and reward were activated. 109 00:07:11,537 --> 00:07:15,117 And not by chance, one of those areas was indeed the insula. 110 00:07:15,993 --> 00:07:19,923 The insula seems to be related, along with other areas of the brain, 111 00:07:19,923 --> 00:07:22,553 with functions 112 00:07:22,553 --> 00:07:26,305 that allow us to be aware that we're in love. 113 00:07:26,305 --> 00:07:29,555 It allows us to say, "This is the person I am in love with." 114 00:07:30,435 --> 00:07:33,015 And also because of its connections with the brain, 115 00:07:33,015 --> 00:07:37,105 with the heart and with the bowel, 116 00:07:37,105 --> 00:07:40,335 makes it possible that when we are with our beloved 117 00:07:40,335 --> 00:07:42,755 we have tachycardia, palpitations, 118 00:07:42,755 --> 00:07:46,405 and that feeling of having butterflies in our stomach, 119 00:07:46,405 --> 00:07:48,385 when we are in love. 120 00:07:48,385 --> 00:07:53,125 So, we fall in love with our brains, and not with our hearts. 121 00:07:54,191 --> 00:07:56,991 This level of interconnection 122 00:07:57,921 --> 00:08:04,321 with our brain and also the insula, 123 00:08:04,321 --> 00:08:08,271 has many functional repercussions, 124 00:08:08,271 --> 00:08:14,441 but it also may result in health problems. 125 00:08:15,817 --> 00:08:20,287 For example, I would like to show you this graphic: 126 00:08:20,287 --> 00:08:24,967 In the horizontal axis we have the months of May, June and July. 127 00:08:25,737 --> 00:08:27,583 And in the vertical axis, 128 00:08:27,583 --> 00:08:31,723 the number of heart attacks in Munich. 129 00:08:35,671 --> 00:08:41,481 In 2003, the number of heart attacks stayed constant, 130 00:08:41,481 --> 00:08:42,811 there were no changes. 131 00:08:43,460 --> 00:08:46,300 In 2005, something similar happened. 132 00:08:47,946 --> 00:08:52,146 In 2006, during May everything stayed the same; 133 00:08:53,386 --> 00:08:57,306 during June and July there was a sudden rise in the number of heart attacks. 134 00:08:58,110 --> 00:08:59,280 What happened? 135 00:09:00,227 --> 00:09:04,277 OK, many of you already noticed: the 2006 World Soccer Cup. 136 00:09:04,875 --> 00:09:05,695 (Laughter) 137 00:09:06,234 --> 00:09:09,604 And each match played by Germany, 138 00:09:09,604 --> 00:09:12,634 is represented by each peak you see in this graphic. 139 00:09:15,157 --> 00:09:19,707 Most interesting is that peak number 5, 140 00:09:20,627 --> 00:09:26,567 is the match for quarter finals between Germany and Argentina 141 00:09:27,892 --> 00:09:30,232 which final result I'd rather not mention. 142 00:09:30,232 --> 00:09:31,087 (Laughter) 143 00:09:32,067 --> 00:09:36,487 This match was being watched by a friend called Hans at his house. 144 00:09:37,891 --> 00:09:40,431 Hans was sitting in front of the TV, 145 00:09:40,431 --> 00:09:45,461 and saw the first and the second half which ended even 146 00:09:45,461 --> 00:09:47,511 and all the definition by penalty. 147 00:09:47,511 --> 00:09:49,691 Germany was winning 4 to 2, 148 00:09:50,594 --> 00:09:52,254 the last penalty pending, 149 00:09:54,094 --> 00:09:57,964 Cambiasso prepares to kick and Lehmann is at the soccer goal. 150 00:09:59,437 --> 00:10:03,602 Cambiasso kicks, Lehmann gets it, Germany classifies, 151 00:10:03,602 --> 00:10:08,335 and Hans, a extremely passionate fan, 152 00:10:08,335 --> 00:10:09,351 (Laughter) 153 00:10:10,471 --> 00:10:14,441 screams like ever, releases all his energy and adrenaline accumulated 154 00:10:14,441 --> 00:10:17,771 during those 90 minutes plus penalties, 155 00:10:17,771 --> 00:10:21,381 and after finishing screaming 156 00:10:21,381 --> 00:10:23,991 ends up in hospital with a heart attack. 157 00:10:25,132 --> 00:10:26,752 Like many other Germans 158 00:10:26,752 --> 00:10:30,542 that day when the number of heart attacks in Munich tripled. 159 00:10:31,862 --> 00:10:35,593 Hans is a living example 160 00:10:35,593 --> 00:10:39,593 of how some emotions affecting our brain 161 00:10:39,593 --> 00:10:45,173 result in cardiac problems. 162 00:10:46,332 --> 00:10:50,272 The stress suffered by Hans, that adrenaline overdose 163 00:10:50,272 --> 00:10:53,152 compromised his heart and resulted in a heart attack. 164 00:10:53,711 --> 00:10:56,451 So, here we ask ourselves, 165 00:10:57,744 --> 00:11:01,934 do we have to give up and accept that we are exposed 166 00:11:01,934 --> 00:11:06,004 to what this complex brain-heart system 167 00:11:06,004 --> 00:11:07,834 exposes us to, regarding our emotions? 168 00:11:07,834 --> 00:11:09,814 Or is there something we can do? 169 00:11:10,832 --> 00:11:17,712 Science is opening many doors, one of them to ancient techniques. 170 00:11:19,064 --> 00:11:22,064 Techniques that albeit having thousands and thousands of years, 171 00:11:22,064 --> 00:11:27,372 have only been explored serious and intensively during the last years. 172 00:11:27,372 --> 00:11:29,992 One of them is "mindfulness." 173 00:11:31,731 --> 00:11:34,871 Mindfulness is somewhat a form of meditation 174 00:11:34,871 --> 00:11:39,781 that allows us to concentrate in what's going on around, 175 00:11:41,098 --> 00:11:44,498 in physical sensations, emotions, 176 00:11:45,278 --> 00:11:46,996 and in messages from our bodies. 177 00:11:46,996 --> 00:11:51,181 Does this "messages from our bodies" ring a bell to you? Interoception? 178 00:11:52,549 --> 00:11:56,179 When I heard about mindfulness 10 or 12 years ago, 179 00:11:56,179 --> 00:11:58,999 I was absolutely skeptical because, sure enough, 180 00:11:58,999 --> 00:12:02,509 there was no scientific evidence, none. 181 00:12:02,509 --> 00:12:06,449 And as we tend to think with scientific and medical minds, 182 00:12:06,449 --> 00:12:08,799 if is not proven, it's useless. 183 00:12:09,618 --> 00:12:13,098 So look at what happened during the last 10 years. 184 00:12:13,098 --> 00:12:14,928 From 2005 to 2015: 185 00:12:14,928 --> 00:12:19,118 Scientific publications which have the word "mindfulness" in their title. 186 00:12:20,174 --> 00:12:23,106 An important increase and most of them, 187 00:12:24,176 --> 00:12:28,136 the most important part of the publications you're seeing, 188 00:12:28,136 --> 00:12:32,366 is related to how useful mindfulness can be to alleviate things like stress. 189 00:12:33,295 --> 00:12:36,175 I know you are skeptical 190 00:12:37,045 --> 00:12:39,245 and have a curious mind 191 00:12:39,245 --> 00:12:42,985 and you won't believe anything I say. 192 00:12:42,985 --> 00:12:45,855 So let's pretend you're scientists, 193 00:12:45,855 --> 00:12:49,525 and I ask you to think which stressful situation we may use 194 00:12:49,535 --> 00:12:54,085 to prove whether mindfulness is useful in fighting stress or not. 195 00:12:55,295 --> 00:12:57,472 Which is the worst-case scenario? 196 00:12:58,097 --> 00:12:59,077 War. 197 00:13:01,757 --> 00:13:04,127 In California, there is a center 198 00:13:04,127 --> 00:13:08,327 where Marines are trained before being sent to combat. 199 00:13:08,327 --> 00:13:11,457 It's the last training when a drill is carried out, 200 00:13:12,467 --> 00:13:13,697 most stressful, 201 00:13:14,757 --> 00:13:19,487 where Marines are faced with soldiers resembling 202 00:13:19,487 --> 00:13:20,807 those they will confront. 203 00:13:21,767 --> 00:13:23,587 Noises are the same, 204 00:13:23,587 --> 00:13:25,947 smells are the same, 205 00:13:27,338 --> 00:13:29,098 and said by they themselves, 206 00:13:29,098 --> 00:13:31,688 it's the most stressful moment before going to war. 207 00:13:34,009 --> 00:13:36,069 In this training center, 208 00:13:36,069 --> 00:13:40,069 half the Marines were offered to do mindfulness during eight weeks. 209 00:13:40,069 --> 00:13:42,409 The rest had usual training. 210 00:13:43,754 --> 00:13:48,294 They did mindfulness training, and went through this terrible drill, 211 00:13:49,514 --> 00:13:52,224 and afterwards, they completed a questionnaire 212 00:13:52,224 --> 00:13:55,154 assessing how stressed they were. 213 00:13:56,014 --> 00:13:58,744 Interestingly, those who underwent mindfulness training, 214 00:13:58,744 --> 00:14:01,814 were much less stressed out, than those who didn't. 215 00:14:01,814 --> 00:14:05,304 You may say, "Of course, they were biased, 216 00:14:05,304 --> 00:14:08,884 as they did mindfulness, they were bound to say they were less stressed." 217 00:14:08,884 --> 00:14:12,834 But they were also measured a protein in their blood released by the brain 218 00:14:12,834 --> 00:14:14,864 in extremely stressful situations. 219 00:14:14,864 --> 00:14:18,744 And those who had done mindfulness had much lower levels 220 00:14:18,744 --> 00:14:20,824 than those who had not. 221 00:14:20,824 --> 00:14:23,534 So, there's an objective and a subjective demonstration 222 00:14:23,534 --> 00:14:27,144 that there is something we can do to diminish stress. 223 00:14:27,144 --> 00:14:32,434 And there are plenty of experiments like this one, portrayed in this graphic. 224 00:14:34,043 --> 00:14:39,193 Thus, it seems that thanks to practices existing for a long time, 225 00:14:39,193 --> 00:14:41,203 and which science is proving nowadays, 226 00:14:41,203 --> 00:14:45,573 we may have the possibility of decreasing the impact some emotions have 227 00:14:45,573 --> 00:14:48,323 on our health and on our heart-brain system. 228 00:14:48,323 --> 00:14:51,213 Maybe in the future, science will tell, 229 00:14:51,213 --> 00:14:56,423 even diseases like stroke and heart attacks may be prevented 230 00:14:56,423 --> 00:14:58,623 by these kind of practices. 231 00:14:59,376 --> 00:15:01,766 For now, I think we all have 232 00:15:03,230 --> 00:15:07,530 to acknowledge the genius of Aristotle, the first to think 233 00:15:07,530 --> 00:15:10,580 that heart and brain act as a system. 234 00:15:11,673 --> 00:15:16,693 And I think it is good to remember the words by a wise man who said, 235 00:15:16,693 --> 00:15:21,113 "A good head and a good heart are always a formidable combination." 236 00:15:21,113 --> 00:15:22,493 Thank you very much. 237 00:15:22,893 --> 00:15:24,795 (Applause)