WEBVTT 00:00:06.898 --> 00:00:09.219 Cigarettes aren’t good for us. 00:00:09.219 --> 00:00:13.865 That’s hardly news--we’ve known about the dangers of smoking for decades. 00:00:13.865 --> 00:00:16.860 But how exactly do cigarettes harm us? 00:00:16.860 --> 00:00:19.192 Let’s look at what happens as their ingredients 00:00:19.192 --> 00:00:20.851 make their way through our bodies, 00:00:20.851 --> 00:00:25.478 and how we benefit physically when we finally give up smoking. NOTE Paragraph 00:00:25.478 --> 00:00:27.358 With each inhalation, 00:00:27.358 --> 00:00:31.158 smoke brings its more than 5,000 chemical substances 00:00:31.158 --> 00:00:33.766 into contact with the body’s tissues. 00:00:33.766 --> 00:00:37.444 From the start, tar, a black, resinous material, 00:00:37.444 --> 00:00:39.825 begins to coat the teeth and gums, 00:00:39.825 --> 00:00:43.708 damaging tooth enamel, and eventually causing decay. 00:00:43.708 --> 00:00:47.721 Over time, smoke also damages nerve-endings in the nose, 00:00:47.721 --> 00:00:50.006 causing loss of smell. NOTE Paragraph 00:00:50.006 --> 00:00:51.815 Inside the airways and lungs, 00:00:51.815 --> 00:00:54.604 smoke increases the likelihood of infections, 00:00:54.604 --> 00:00:59.277 as well as chronic diseases like bronchitis and emphysema. 00:00:59.277 --> 00:01:01.707 It does this by damaging the cilia, 00:01:01.707 --> 00:01:07.067 tiny hairlike structures whose job it is to keep the airways clean. 00:01:07.067 --> 00:01:09.504 It then fills the alveoli, 00:01:09.504 --> 00:01:13.654 tiny air sacs that enable the exchange of oxygen and carbon dioxide 00:01:13.654 --> 00:01:15.258 between the lungs and blood. 00:01:15.258 --> 00:01:20.251 A toxic gas called carbon monoxide crosses that membrane into the blood, 00:01:20.251 --> 00:01:21.958 binding to hemoglobin 00:01:21.958 --> 00:01:23.561 and displacing the oxygen 00:01:23.561 --> 00:01:26.771 it would usually have transported around the body. 00:01:26.771 --> 00:01:30.380 That’s one of the reasons smoking can lead to oxygen deprivation 00:01:30.380 --> 00:01:32.954 and shortness of breath. NOTE Paragraph 00:01:32.954 --> 00:01:35.121 Within about 10 seconds, 00:01:35.121 --> 00:01:38.897 the bloodstream carries a stimulant called nicotine to the brain, 00:01:38.897 --> 00:01:42.413 triggering the release of dopamine and other neurotransmitters 00:01:42.413 --> 00:01:43.689 including endorphins 00:01:43.689 --> 00:01:47.684 that create the pleasurable sensations which make smoking highly addictive. 00:01:47.684 --> 00:01:50.043 Nicotine and other chemicals from the cigarette 00:01:50.043 --> 00:01:53.006 simultaneously cause constriction of blood vessels 00:01:53.006 --> 00:01:55.942 and damage their delicate endothelial lining, 00:01:55.942 --> 00:01:57.675 restricting blood flow. 00:01:57.675 --> 00:02:00.957 These vascular effects lead to thickening of blood vessel walls 00:02:00.957 --> 00:02:03.471 and enhance blood platelet stickiness, 00:02:03.471 --> 00:02:06.055 increasing the likelihood that clots will form 00:02:06.055 --> 00:02:08.929 and trigger heart attacks and strokes. NOTE Paragraph 00:02:08.929 --> 00:02:12.689 Many of the chemicals inside cigarettes can trigger dangerous mutations 00:02:12.689 --> 00:02:15.965 in the body’s DNA that make cancers form. 00:02:15.965 --> 00:02:18.955 Additionally, ingredients like arsenic and nickel 00:02:18.955 --> 00:02:21.524 may disrupt the process of DNA repair, 00:02:21.524 --> 00:02:25.443 thus compromising the body’s ability to fight many cancers. 00:02:25.443 --> 00:02:29.175 In fact, about one of every three cancer deaths in the United States 00:02:29.175 --> 00:02:31.218 is caused by smoking. NOTE Paragraph 00:02:31.218 --> 00:02:33.571 And it’s not just lung cancer. 00:02:33.571 --> 00:02:36.938 Smoking can cause cancer in multiple tissues and organs, 00:02:36.938 --> 00:02:38.745 as well as damaged eyesight 00:02:38.745 --> 00:02:40.901 and weakened bones. 00:02:40.901 --> 00:02:43.110 It makes it harder for women to get pregnant. 00:02:43.110 --> 00:02:46.088 And in men, it can cause erectile dysfunction. NOTE Paragraph 00:02:46.088 --> 00:02:47.785 But for those who quit smoking, 00:02:47.785 --> 00:02:49.763 there’s a huge positive upside 00:02:49.763 --> 00:02:53.328 with almost immediate and long-lasting physical benefits. NOTE Paragraph 00:02:53.328 --> 00:02:57.010 Just 20 minutes after a smoker’s final cigarette, 00:02:57.010 --> 00:03:00.841 their heart rate and blood pressure begin to return to normal. 00:03:00.841 --> 00:03:04.259 After 12 hours, carbon monoxide levels stabilize, 00:03:04.259 --> 00:03:07.023 increasing the blood’s oxygen-carrying capacity. 00:03:07.023 --> 00:03:08.540 A day after ceasing, 00:03:08.540 --> 00:03:13.894 heart attack risk begins to decrease as blood pressure and heart rates normalize. 00:03:13.894 --> 00:03:15.170 After two days, 00:03:15.170 --> 00:03:20.094 the nerve endings responsible for smell and taste start to recover. NOTE Paragraph 00:03:20.094 --> 00:03:23.520 Lungs become healthier after about one month, 00:03:23.520 --> 00:03:25.875 with less coughing and shortness of breath. 00:03:25.875 --> 00:03:28.999 The delicate hair-like cilia in the airways and lungs 00:03:28.999 --> 00:03:31.077 start recovering within weeks, 00:03:31.077 --> 00:03:35.340 and are restored after 9 months, improving resistance to infection. NOTE Paragraph 00:03:35.340 --> 00:03:37.717 By the one-year anniversary of quitting, 00:03:37.717 --> 00:03:42.761 heart disease risk plummets to half as blood vessel function improves. 00:03:42.761 --> 00:03:44.025 Five years in, 00:03:44.025 --> 00:03:46.845 the chance of a clot forming dramatically declines, 00:03:46.845 --> 00:03:49.751 and the risk of stroke continues to reduce. 00:03:49.751 --> 00:03:53.352 After ten years, the chances of developing fatal lung cancer 00:03:53.352 --> 00:03:55.398 go down by 50%, 00:03:55.398 --> 00:04:00.169 probably because the body’s ability to repair DNA is once again restored. 00:04:00.169 --> 00:04:04.008 Fifteen years in, the likelihood of developing coronary heart disease 00:04:04.008 --> 00:04:07.522 is essentially the same as that of a non-smoker. NOTE Paragraph 00:04:07.522 --> 00:04:10.818 There’s no point pretending this is all easy to achieve. 00:04:10.818 --> 00:04:13.640 Quitting can lead to anxiety and depression, 00:04:13.640 --> 00:04:15.582 resulting from nicotine withdrawal. 00:04:15.582 --> 00:04:19.292 But fortunately, such effects are usually temporary. 00:04:19.292 --> 00:04:23.980 And quitting is getting easier, thanks to a growing arsenal of tools. 00:04:23.980 --> 00:04:26.426 Nicotine replacement therapy through gum, 00:04:26.426 --> 00:04:27.655 skin patches, 00:04:27.655 --> 00:04:28.439 lozenges, 00:04:28.439 --> 00:04:29.352 and sprays 00:04:29.352 --> 00:04:32.345 may help wean smokers off cigarettes. 00:04:32.345 --> 00:04:35.458 They work by stimulating nicotine receptors in the brain 00:04:35.458 --> 00:04:37.850 and thus preventing withdrawal symptoms, 00:04:37.850 --> 00:04:40.758 without the addition of other harmful chemicals. 00:04:40.758 --> 00:04:42.470 Counselling and support groups, 00:04:42.470 --> 00:04:44.413 cognitive behavioral therapy, 00:04:44.413 --> 00:04:46.606 and moderate intensity exercise 00:04:46.606 --> 00:04:50.061 also help smokers stay cigarette-free. NOTE Paragraph 00:04:50.061 --> 00:04:51.608 That’s good news, 00:04:51.608 --> 00:04:56.256 since quitting puts you and your body on the path back to health.