1 00:00:07,058 --> 00:00:09,369 Cigarettes aren’t good for us. 2 00:00:09,369 --> 00:00:13,865 That’s hardly news--we’ve known about the dangers of smoking for decades. 3 00:00:13,865 --> 00:00:17,150 But how exactly do cigarettes harm us? 4 00:00:17,150 --> 00:00:19,422 Let’s look at what happens as their ingredients 5 00:00:19,422 --> 00:00:21,151 make their way through our bodies, 6 00:00:21,151 --> 00:00:25,378 and how we benefit physically when we finally give up smoking. 7 00:00:25,378 --> 00:00:27,358 With each inhalation, 8 00:00:27,358 --> 00:00:31,158 smoke brings its more than 5,000 chemical substances 9 00:00:31,158 --> 00:00:33,896 into contact with the body’s tissues. 10 00:00:33,896 --> 00:00:37,444 From the start, tar, a black, resinous material, 11 00:00:37,444 --> 00:00:39,825 begins to coat the teeth and gums, 12 00:00:39,825 --> 00:00:43,708 damaging tooth enamel, and eventually causing decay. 13 00:00:43,708 --> 00:00:47,721 Over time, smoke also damages nerve-endings in the nose, 14 00:00:47,721 --> 00:00:49,366 causing loss of smell. 15 00:00:49,366 --> 00:00:51,815 Inside the airways and the lungs, 16 00:00:51,815 --> 00:00:54,604 smoke increases the likelihood of infections, 17 00:00:54,604 --> 00:00:58,587 as well as chronic diseases like bronchitis and emphysema. 18 00:00:58,587 --> 00:01:01,707 It does this by damaging the cilia, 19 00:01:01,707 --> 00:01:07,237 tiny hairlike structures whose job it is to keep the airways clean. 20 00:01:07,237 --> 00:01:09,504 It then fills the alveoli, 21 00:01:09,504 --> 00:01:13,654 tiny air sacs that enable the exchange of oxygen and carbon dioxide 22 00:01:13,654 --> 00:01:15,418 between the lungs and blood. 23 00:01:15,418 --> 00:01:20,251 A toxic gas called carbon monoxide crosses that membrane into the blood, 24 00:01:20,251 --> 00:01:21,958 binding to hemoglobin 25 00:01:21,958 --> 00:01:23,821 and displacing the oxygen 26 00:01:23,821 --> 00:01:26,771 it would usually have transported around the body. 27 00:01:26,771 --> 00:01:30,380 That’s one of the reasons smoking can lead to oxygen deprivation 28 00:01:30,380 --> 00:01:32,704 and shortness of breath. 29 00:01:32,704 --> 00:01:35,121 Within about 10 seconds, 30 00:01:35,121 --> 00:01:38,987 the bloodstream carries a stimulant called nicotine to the brain, 31 00:01:38,987 --> 00:01:42,413 triggering the release of dopamine and other neurotransmitters 32 00:01:42,413 --> 00:01:43,689 including endorphins 33 00:01:43,689 --> 00:01:47,684 that create the pleasurable sensations which make smoking highly addictive. 34 00:01:47,684 --> 00:01:50,043 Nicotine and other chemicals from the cigarette 35 00:01:50,043 --> 00:01:53,006 simultaneously cause constriction of blood vessels 36 00:01:53,006 --> 00:01:55,942 and damage their delicate endothelial lining, 37 00:01:55,942 --> 00:01:57,905 restricting blood flow. 38 00:01:57,905 --> 00:02:00,957 These vascular effects lead to thickening of blood vessel walls 39 00:02:00,957 --> 00:02:03,471 and enhance blood platelet stickiness, 40 00:02:03,471 --> 00:02:06,055 increasing the likelihood that clots will form 41 00:02:06,055 --> 00:02:08,929 and trigger heart attacks and strokes. 42 00:02:08,929 --> 00:02:12,689 Many of the chemicals inside cigarettes can trigger dangerous mutations 43 00:02:12,689 --> 00:02:16,095 in the body’s DNA that make cancers form. 44 00:02:16,095 --> 00:02:18,955 Additionally, ingredients like arsenic and nickel 45 00:02:18,955 --> 00:02:21,524 may disrupt the process of DNA repair, 46 00:02:21,524 --> 00:02:25,003 thus compromising the body’s ability to fight many cancers. 47 00:02:25,003 --> 00:02:29,175 In fact, about one of every three cancer deaths in the United States 48 00:02:29,175 --> 00:02:31,218 is caused by smoking. 49 00:02:31,218 --> 00:02:33,571 And it’s not just lung cancer. 50 00:02:33,571 --> 00:02:36,938 Smoking can cause cancer in multiple tissues and organs, 51 00:02:36,938 --> 00:02:38,745 as well as damaged eyesight 52 00:02:38,745 --> 00:02:40,901 and weakened bones. 53 00:02:40,901 --> 00:02:43,110 It makes it harder for women to get pregnant. 54 00:02:43,110 --> 00:02:46,088 And in men, it can cause erectile dysfunction. 55 00:02:46,088 --> 00:02:47,785 But for those who quit smoking, 56 00:02:47,785 --> 00:02:49,763 there’s a huge positive upside 57 00:02:49,763 --> 00:02:53,328 with almost immediate and long-lasting physical benefits. 58 00:02:53,328 --> 00:02:57,010 Just 20 minutes after a smoker’s final cigarette, 59 00:02:57,010 --> 00:03:00,841 their heart rate and blood pressure begin to return to normal. 60 00:03:00,841 --> 00:03:04,259 After 12 hours, carbon monoxide levels stabilize, 61 00:03:04,259 --> 00:03:07,143 increasing the blood’s oxygen-carrying capacity. 62 00:03:07,143 --> 00:03:08,540 A day after ceasing, 63 00:03:08,540 --> 00:03:13,894 heart attack risk begins to decrease as blood pressure and heart rates normalize. 64 00:03:13,894 --> 00:03:15,170 After two days, 65 00:03:15,170 --> 00:03:20,094 the nerve endings responsible for smell and taste start to recover. 66 00:03:20,094 --> 00:03:23,520 Lungs become healthier after about one month, 67 00:03:23,520 --> 00:03:25,875 with less coughing and shortness of breath. 68 00:03:25,875 --> 00:03:28,999 The delicate hair-like cilia in the airways and lungs 69 00:03:28,999 --> 00:03:31,077 start recovering within weeks, 70 00:03:31,077 --> 00:03:35,340 and are restored after 9 months, improving resistance to infection. 71 00:03:35,340 --> 00:03:37,717 By the one-year anniversary of quitting, 72 00:03:37,717 --> 00:03:42,891 heart disease risk plummets to half as blood vessel function improves. 73 00:03:42,891 --> 00:03:44,155 Five years in, 74 00:03:44,155 --> 00:03:46,845 the chance of a clot forming dramatically declines, 75 00:03:46,845 --> 00:03:49,901 and the risk of stroke continues to reduce. 76 00:03:49,901 --> 00:03:53,352 After ten years, the chances of developing fatal lung cancer 77 00:03:53,352 --> 00:03:55,398 go down by 50%, 78 00:03:55,398 --> 00:04:00,169 probably because the body’s ability to repair DNA is once again restored. 79 00:04:00,169 --> 00:04:04,008 Fifteen years in, the likelihood of developing coronary heart disease 80 00:04:04,008 --> 00:04:07,812 is essentially the same as that of a non-smoker. 81 00:04:07,812 --> 00:04:10,818 There’s no point pretending this is all easy to achieve. 82 00:04:10,818 --> 00:04:13,640 Quitting can lead to anxiety and depression, 83 00:04:13,640 --> 00:04:15,582 resulting from nicotine withdrawal. 84 00:04:15,582 --> 00:04:19,292 But fortunately, such effects are usually temporary. 85 00:04:19,292 --> 00:04:23,980 And quitting is getting easier, thanks to a growing arsenal of tools. 86 00:04:23,980 --> 00:04:26,426 Nicotine replacement therapy through gum, 87 00:04:26,426 --> 00:04:27,655 skin patches, 88 00:04:27,655 --> 00:04:28,649 lozenges, 89 00:04:28,649 --> 00:04:29,732 and sprays 90 00:04:29,732 --> 00:04:32,345 may help wean smokers off cigarettes. 91 00:04:32,345 --> 00:04:35,458 They work by stimulating nicotine receptors in the brain 92 00:04:35,458 --> 00:04:37,850 and thus preventing withdrawal symptoms, 93 00:04:37,850 --> 00:04:40,758 without the addition of other harmful chemicals. 94 00:04:40,758 --> 00:04:42,470 Counselling and support groups, 95 00:04:42,470 --> 00:04:44,413 cognitive behavioral therapy, 96 00:04:44,413 --> 00:04:46,606 and moderate intensity exercise 97 00:04:46,606 --> 00:04:50,061 also help smokers stay cigarette-free. 98 00:04:50,061 --> 00:04:51,608 That’s good news, 99 00:04:51,608 --> 00:04:56,256 since quitting puts you and your body on the path back to health.