0:00:05.774,0:00:09.298 When I was a kid, the disaster[br]we worried about most 0:00:09.298,0:00:12.029 was a nuclear war. 0:00:12.029,0:00:15.085 That's why we had a barrel like this[br]down in our basement, 0:00:15.085,0:00:18.456 filled with cans of food and water. 0:00:18.456,0:00:19.901 When the nuclear attack came, 0:00:19.901,0:00:21.747 we were supposed to go downstairs, 0:00:21.747,0:00:25.877 hunker down, and eat out of that barrel. 0:00:25.877,0:00:29.924 Today the greatest risk [br]of global catastrophe 0:00:29.924,0:00:32.301 doesn't look like this. 0:00:32.301,0:00:36.438 Instead, it looks like this. 0:00:36.438,0:00:41.929 If anything kills over 10 million people[br]in the next few decades, 0:00:41.929,0:00:45.504 it's most likely to be [br]a highly infectious virus 0:00:45.504,0:00:47.792 rather than a war. 0:00:47.792,0:00:51.679 Not missles, but microbes. 0:00:51.679,0:00:53.878 Now part of the reason for this is that[br] 0:00:53.878,0:00:58.081 we've invested a huge amount[br]in nuclear deterrants. 0:00:58.081,0:01:04.129 But we've actually invested very little [br]in a system to stop an epidemic. 0:01:04.129,0:01:07.873 We're not ready for the next epidemic. 0:01:07.873,0:01:09.758 Let's look at Ebola. 0:01:09.758,0:01:13.855 I'm sure all of you read about [br]it in the newspaper, 0:01:13.855,0:01:15.401 lots of tough challenges. 0:01:15.401,0:01:19.676 I followed it carefully through [br]the case analysis tools we use 0:01:19.676,0:01:23.721 to track polio eradication. 0:01:23.721,0:01:25.573 And as you look at what went on, 0:01:25.573,0:01:30.331 the problem wasn't that there was[br]a system that didn't work well enough, 0:01:30.331,0:01:34.589 the problem was that we didn't have[br]a system at all. 0:01:34.589,0:01:39.028 In fact, there's some pretty obvious[br]key missing pieces. 0:01:39.028,0:01:43.440 We didn't have a group of epidemiologists[br]ready to go who would have gone, 0:01:43.440,0:01:47.696 seen what the disease was,[br]seen how far it had spread. 0:01:47.696,0:01:50.452 The case reports came in on paper. 0:01:50.452,0:01:52.808 It was very delayed before[br]they were put online 0:01:52.808,0:01:55.592 and they were extremely inaccurate. 0:01:55.592,0:01:57.858 We didn't have a medical team ready to go. 0:01:57.858,0:02:00.453 We didn't have a way of preparing people. 0:02:00.453,0:02:05.784 Now, Médecins Sans Frontières did a [br]great job orchestrating volunteers. 0:02:05.784,0:02:08.880 But even so, we were far slower[br]than we should have been 0:02:08.880,0:02:12.362 getting the thousands of workers[br]into these countries. 0:02:12.362,0:02:14.337 And a large epidemic would require us[br] 0:02:14.337,0:02:19.292 to have hundreds of thousands of workers. 0:02:20.752,0:02:25.155 There was noone there to look[br]at treatment approaches. 0:02:25.155,0:02:26.946 No one to look at the diagnostics. 0:02:26.946,0:02:30.243 No one to figure out what tools[br]should be used. 0:02:30.243,0:02:33.993 As an example, we could have taken[br]the blood of survivors, 0:02:33.993,0:02:39.158 processed it, and put that plasma[br]back in people to protect them. 0:02:39.158,0:02:41.764 But that was never tried. 0:02:41.764,0:02:43.520 So there was a lot that was missing. 0:02:43.520,0:02:48.305 And these things are really [br]a global failure. 0:02:48.305,0:02:51.303 The WHO is funded to monitor epidemics, 0:02:51.303,0:02:55.049 but not to do these things I talked about. 0:02:55.049,0:02:57.842 Now in the movies, it's quiet different. 0:02:57.842,0:03:01.674 There's a group of [br]handsome epidemiologists 0:03:01.674,0:03:06.036 ready to go, they move in, [br]they save the day. 0:03:06.036,0:03:10.177 But that's just pure Hollywood. 0:03:10.177,0:03:13.887 The failure to prepare could allow[br]the next epidemic 0:03:13.887,0:03:18.735 to be dramatically [br]more devastating than Ebola 0:03:18.735,0:03:24.311 Let's look at the progression [br]of Ebola over this year. 0:03:24.311,0:03:27.149 About 10,000 people died, [br] 0:03:27.149,0:03:31.846 and nearly all were in the three[br]West African countries. 0:03:31.846,0:03:34.433 There's three reasons why[br]it didn't spread more. 0:03:34.433,0:03:37.274 The first is that there was [br]a lot of heroic work 0:03:37.274,0:03:38.808 by the health workers. 0:03:38.808,0:03:42.136 They found the people and they [br]prevented more infections. 0:03:42.136,0:03:44.761 The second is the nature of the virus. 0:03:44.761,0:03:47.697 Ebola does not spread through the air. 0:03:47.697,0:03:51.240 And by the time you're contagious,[br]most people are so sick 0:03:51.240,0:03:54.820 that they're bedridden. 0:03:54.820,0:03:58.411 Third, it didn't get into [br]many urban areas. 0:03:58.411,0:03:59.915 And that was just luck. 0:03:59.915,0:04:02.095 If it had gotten into a lot [br]more urban areas, 0:04:02.095,0:04:06.157 the case numbers would have [br]been much larger. 0:04:06.157,0:04:09.466 So next time, we might not be so lucky. 0:04:09.466,0:04:14.530 You can have a virus where people [br]feel well enough while they're infectious, 0:04:14.530,0:04:17.842 that they get on a plane[br]or they go to a market. 0:04:17.842,0:04:20.846 The source of the virus could be [br]a natural epidemic like Ebola, 0:04:20.846,0:04:22.826 or it could be bioterrorism. 0:04:22.826,0:04:25.935 And so there are things that would [br]literally make things 0:04:25.935,0:04:27.904 a thousand times worse. 0:04:27.904,0:04:33.475 In fact, let's look at a model[br]of a virus spread through the air, 0:04:33.475,0:04:37.950 like the Spanish Flu back in 1918. 0:04:37.950,0:04:39.560 So here's what would happen: 0:04:39.560,0:04:43.558 it would spread throughout the world[br]very, very quickly. 0:04:43.558,0:04:48.683 And you can see, over 30 million people[br]died from that epidemic. 0:04:48.683,0:04:50.496 So this is a seriousl problem. 0:04:50.496,0:04:52.257 We should be concerned. 0:04:52.257,0:04:56.982 But in fact, we can build[br]a really good response system. 0:04:56.982,0:05:01.836 We have the benefits of all the science[br]and technology that we talk about here. 0:05:01.836,0:05:04.563 We've got cell phones to get [br]information from the public 0:05:04.563,0:05:06.140 and get information out to them. 0:05:06.140,0:05:08.839 We have satellite maps where [br]we can see where people are 0:05:08.839,0:05:10.221 and where they're moving. 0:05:10.221,0:05:13.857 We have advances in biology[br]that should dramatically change 0:05:13.857,0:05:16.453 the turnaround time to look at a pathogen 0:05:16.453,0:05:22.252 and be able to make drugs and vaccines[br]that fit for that pathogen. 0:05:22.252,0:05:25.158 So we can have tools, but those tools[br]need to be put into 0:05:25.158,0:05:27.500 an overall global health system. 0:05:27.500,0:05:29.793 And we need preparedness. 0:05:29.793,0:05:32.257 The best lessons, I think, on how [br]to get prepared 0:05:32.257,0:05:35.108 are, again, what we do for war. 0:05:35.108,0:05:39.005 For soldiers, we have them full-time,[br]ready to go. 0:05:39.005,0:05:42.316 We have reserves that can scale us up[br]to large numbers. 0:05:42.316,0:05:46.005 NATO has a mobile unit [br]that can deploy very rapidly. 0:05:46.005,0:05:49.165 NATO does a lot of war games to check, [br]"Are people well trained? 0:05:49.165,0:05:52.265 Do they understand about fuel[br]and logistics 0:05:52.265,0:05:54.243 and the same radio frequencies?" 0:05:54.243,0:05:56.779 So they are absolutely ready to go. 0:05:56.779,0:06:01.474 So those are the kinds of things[br]we need to deal with an epidemic. 0:06:01.474,0:06:03.301 What are the key pieces? 0:06:03.301,0:06:08.591 First, we need strong health systems[br]for countries. 0:06:08.591,0:06:11.249 That's where mothers can give birth safely, 0:06:11.249,0:06:13.177 kids can get all their vaccines. 0:06:13.177,0:06:18.154 But, also where we'll see[br]the outbreak very early on. 0:06:18.154,0:06:20.105 We need a medical reserve corps: 0:06:20.105,0:06:22.501 lots of people who've got the training[br]and background 0:06:22.501,0:06:25.853 who are ready to go, with the expertise. 0:06:25.853,0:06:29.036 And then we need to pair those[br]medical people 0:06:29.036,0:06:30.549 with the military, 0:06:30.549,0:06:34.417 taking advantage of the military's ability[br]to move fast, do logistics 0:06:34.417,0:06:36.450 and secure areas. 0:06:36.450,0:06:41.615 We need to do simulations: germs games,[br]not war games, 0:06:41.615,0:06:44.487 so that we see where the holes are. 0:06:44.487,0:06:48.473 The last time a germ game was done[br]in the United States 0:06:48.473,0:06:50.713 was back in 2001, and it didn't go so well. 0:06:50.713,0:06:55.490 So far the score is germs: 1, people: 0. 0:06:55.490,0:07:01.879 Finally, we need lots of advanced R&D[br]in areas of vaccines and diagnostics. 0:07:01.879,0:07:05.246 There are some big breakthroughs, [br]like the Adeno-associated virus, 0:07:05.246,0:07:09.229 that could work very, very quickly. 0:07:09.229,0:07:12.599 Now I don't have an exact budget[br]for what this would cost,[br] 0:07:12.599,0:07:17.685 but I'm quite sure that it's very modest[br]compared to the potential harm. 0:07:17.685,0:07:21.740 The World Bank estimates that [br]if we have a worldwide flu epidemic, 0:07:21.740,0:07:25.465 global wealth would go down[br]by over 3 trillion dollars. 0:07:25.465,0:07:29.802 We'd have millions and millions of deaths. 0:07:29.802,0:07:32.927 These investments offer [br]significant benefits beyond just 0:07:32.927,0:07:34.648 being ready for an epidemic. 0:07:34.648,0:07:36.892 The primary healthcare, the R&D,[br]those things[br] 0:07:36.892,0:07:41.170 would reduce global health equity[br]and make the world more just, 0:07:41.170,0:07:43.256 as well as more safe. 0:07:43.256,0:07:47.514 So I think this should absolutely[br]be a priority. 0:07:47.514,0:07:48.980 There's no need to panic. 0:07:48.980,0:07:51.119 We don't have to horde cans[br]or spaghetti 0:07:51.119,0:07:53.728 or go down into the basement. 0:07:53.728,0:07:55.173 But we need to get going, 0:07:55.173,0:07:58.019 because time is not on our side. 0:07:58.019,0:08:03.524 In fact, if there's one positive thing[br]that can come out of the Ebola epidemic, 0:08:03.524,0:08:09.880 it's that can serve as an early warning,[br]a wake-up call, to get ready. 0:08:09.880,0:08:14.758 If we start now, we can be ready [br]for the next epidemic. 0:08:14.758,0:08:16.114 Thank you. 0:08:16.114,0:08:19.868 (Applause)