1 99:59:59,999 --> 99:59:59,999 When I was a kid, the disaster we worried about most 2 99:59:59,999 --> 99:59:59,999 was a nuclear war. 3 99:59:59,999 --> 99:59:59,999 That's why we had a barrel like this down in our basement, 4 99:59:59,999 --> 99:59:59,999 filled with food and water. 5 99:59:59,999 --> 99:59:59,999 When the nuclear attack came, 6 99:59:59,999 --> 99:59:59,999 we were supposed to go downstairs, 7 99:59:59,999 --> 99:59:59,999 hunker down, and eat out of that barrel. 8 99:59:59,999 --> 99:59:59,999 Today the greatest risk of global catastrophe 9 99:59:59,999 --> 99:59:59,999 doesn't look like this. 10 99:59:59,999 --> 99:59:59,999 Instead, it looks like this. 11 99:59:59,999 --> 99:59:59,999 If anything kills over 10 million people in the next few decades, 12 99:59:59,999 --> 99:59:59,999 it's most likely to be a highly infectious virus 13 99:59:59,999 --> 99:59:59,999 rather than a war. 14 99:59:59,999 --> 99:59:59,999 Not missles, but microbes. 15 99:59:59,999 --> 99:59:59,999 Now part of the reason for this 16 99:59:59,999 --> 99:59:59,999 is that we've invested a huge amount in nuclear deterrants. 17 99:59:59,999 --> 99:59:59,999 But we've actually invested very little in a system to stop an epidemic. 18 99:59:59,999 --> 99:59:59,999 We're not ready for the next epidemic. 19 99:59:59,999 --> 99:59:59,999 Let's look at Ebola. 20 99:59:59,999 --> 99:59:59,999 I'm sure all of you read about it in the newspaper, 21 99:59:59,999 --> 99:59:59,999 lots of touch challenges. 22 99:59:59,999 --> 99:59:59,999 I followed it carefully through the case analysis tools we use 23 99:59:59,999 --> 99:59:59,999 to track polio eradication. 24 99:59:59,999 --> 99:59:59,999 And as you look at what went on, 25 99:59:59,999 --> 99:59:59,999 the problem wasn't that there was a system that didn't work well enough, 26 99:59:59,999 --> 99:59:59,999 the problem was that we didn't have a system at all. 27 99:59:59,999 --> 99:59:59,999 In fact, there's some pretty obvious key missing pieces. 28 99:59:59,999 --> 99:59:59,999 We didn't have a group of epidemiologists ready to go 29 99:59:59,999 --> 99:59:59,999 who would have gone, seen what the disease was, 30 99:59:59,999 --> 99:59:59,999 seen how far it had spread. 31 99:59:59,999 --> 99:59:59,999 The case reports came in on paper. 32 99:59:59,999 --> 99:59:59,999 It was very delayed before they were put online 33 99:59:59,999 --> 99:59:59,999 and they were extremely inaccurate. 34 99:59:59,999 --> 99:59:59,999 We didn't have a medical team ready to go. 35 99:59:59,999 --> 99:59:59,999 We didn't have a way of preparing people. 36 99:59:59,999 --> 99:59:59,999 Now Médecins Sans Frontières did a great job orchestrating volunteers. 37 99:59:59,999 --> 99:59:59,999 But even so, we were far slower than we should have been 38 99:59:59,999 --> 99:59:59,999 getting the thousands of workers into these countries. 39 99:59:59,999 --> 99:59:59,999 And a large epidemic would require us to have hundreds of thousands 40 99:59:59,999 --> 99:59:59,999 of workers. 41 99:59:59,999 --> 99:59:59,999 There was no one there to look at treatment approaches. 42 99:59:59,999 --> 99:59:59,999 No one to look at the diagnostics. 43 99:59:59,999 --> 99:59:59,999 No one to figure out what tools should be used. 44 99:59:59,999 --> 99:59:59,999 As an example, we could have taken the blood of survivors, 45 99:59:59,999 --> 99:59:59,999 processed it, and put that plasma back in people to protect them. 46 99:59:59,999 --> 99:59:59,999 But that was never tried. 47 99:59:59,999 --> 99:59:59,999 So there was a lot that was missing. 48 99:59:59,999 --> 99:59:59,999 And these things are really a global failure. 49 99:59:59,999 --> 99:59:59,999 The WHO is funded to monitor epidemics, 50 99:59:59,999 --> 99:59:59,999 but not to do these things I talked about. 51 99:59:59,999 --> 99:59:59,999 Now in the movies, it's quiet different. 52 99:59:59,999 --> 99:59:59,999 There's a group of handsome epidemiologists 53 99:59:59,999 --> 99:59:59,999 ready to go, they move in, they save the day. 54 99:59:59,999 --> 99:59:59,999 But that's just pure Hollywood. 55 99:59:59,999 --> 99:59:59,999 The failure to prepare could allow the next epidemic 56 99:59:59,999 --> 99:59:59,999 to be dramatically more devastating than Ebola. 57 99:59:59,999 --> 99:59:59,999 Let's look at the progression of Ebola over this year. 58 99:59:59,999 --> 99:59:59,999 About 10,000 people died, 59 99:59:59,999 --> 99:59:59,999 and nearly all were in the three West African countries. 60 99:59:59,999 --> 99:59:59,999 There's three reasons why it didn't spread more. 61 99:59:59,999 --> 99:59:59,999 The first is that there was a lot of heroic work 62 99:59:59,999 --> 99:59:59,999 by the health workers. 63 99:59:59,999 --> 99:59:59,999 They found the people and they prevented more infections. 64 99:59:59,999 --> 99:59:59,999 The second is the nature of the virus. 65 99:59:59,999 --> 99:59:59,999 Ebola does not spread through the air. 66 99:59:59,999 --> 99:59:59,999 And by the time you're contagious, most people are so sick 67 99:59:59,999 --> 99:59:59,999 that they're bedridden. 68 99:59:59,999 --> 99:59:59,999 Third, it didn't get into many urban areas. 69 99:59:59,999 --> 99:59:59,999 And that was just luck. 70 99:59:59,999 --> 99:59:59,999 If it had gotten into a lot more urban areas, 71 99:59:59,999 --> 99:59:59,999 the case numbers would have been much larger. 72 99:59:59,999 --> 99:59:59,999 So next time, we may not be so lucky. 73 99:59:59,999 --> 99:59:59,999 You can have a virus where people feel well enough while they're infectious, 74 99:59:59,999 --> 99:59:59,999 they get on a plane or they go to a market. 75 99:59:59,999 --> 99:59:59,999 The source of the virus could be a natural epidemic like Ebola, 76 99:59:59,999 --> 99:59:59,999 or it could be bioterrorism. 77 99:59:59,999 --> 99:59:59,999 And so there are things that would literally make things 78 99:59:59,999 --> 99:59:59,999 a thousand times worse. 79 99:59:59,999 --> 99:59:59,999 In fact, let's look at a model of a virus spread through the air, 80 99:59:59,999 --> 99:59:59,999 like the Spanish Flu back in 1918. 81 99:59:59,999 --> 99:59:59,999 So here's what would happen: 82 99:59:59,999 --> 99:59:59,999 it would spread throughout the world very, very quickly. 83 99:59:59,999 --> 99:59:59,999 And you can see, over 30 million people died from that epidemic. 84 99:59:59,999 --> 99:59:59,999 So this is a seriousl problem. 85 99:59:59,999 --> 99:59:59,999 We should be concerned. 86 99:59:59,999 --> 99:59:59,999 But in fact, we can build a really good response system. 87 99:59:59,999 --> 99:59:59,999 We have the benefits of all the science and technology that we talked about here. 88 99:59:59,999 --> 99:59:59,999 We've got cell phones to get information from the public 89 99:59:59,999 --> 99:59:59,999 and get information out to them. 90 99:59:59,999 --> 99:59:59,999 We have satellite maps where we can see where we can see where people are 91 99:59:59,999 --> 99:59:59,999 and where they're moving. 92 99:59:59,999 --> 99:59:59,999 We have advances in biology that should dramatically change 93 99:59:59,999 --> 99:59:59,999 the turnaround time to look at a pathogen 94 99:59:59,999 --> 99:59:59,999 and be able to make drugs and vaccines that fit for that pathogen. 95 99:59:59,999 --> 99:59:59,999 So we can have tools, but those tools need to be put into 96 99:59:59,999 --> 99:59:59,999 an overall global health system. 97 99:59:59,999 --> 99:59:59,999 And we need preparedness. 98 99:59:59,999 --> 99:59:59,999 The best lessons, I think, on how to get prepared 99 99:59:59,999 --> 99:59:59,999 are, again, what we do for war. 100 99:59:59,999 --> 99:59:59,999 For soldiers, we have them full-time, ready to go. 101 99:59:59,999 --> 99:59:59,999 We have reserves that can scale us up to large numbers. 102 99:59:59,999 --> 99:59:59,999 NATO has a mobile unit that can deploy very rapidly. 103 99:59:59,999 --> 99:59:59,999 NATO does a lot of war games to check, "Are people well trained? 104 99:59:59,999 --> 99:59:59,999 Do they understand about fuel and logistics 105 99:59:59,999 --> 99:59:59,999 and the same radio frequencies?" 106 99:59:59,999 --> 99:59:59,999 So they are absolutely ready to go. 107 99:59:59,999 --> 99:59:59,999 So those are the kinds of things we need to deal with an epidemic. 108 99:59:59,999 --> 99:59:59,999 What are the key pieces? 109 99:59:59,999 --> 99:59:59,999 First, we need strong health systems for countries. 110 99:59:59,999 --> 99:59:59,999 That's where mothers can give birth safely, 111 99:59:59,999 --> 99:59:59,999 kids can get all their vaccines. 112 99:59:59,999 --> 99:59:59,999 But, also where we'll see the outbreak very early on. 113 99:59:59,999 --> 99:59:59,999 We need a medical reserve corps: 114 99:59:59,999 --> 99:59:59,999 lots of people who've got the training and background 115 99:59:59,999 --> 99:59:59,999 who are ready to go, with the expertise. 116 99:59:59,999 --> 99:59:59,999 And then we need to pair those medical people 117 99:59:59,999 --> 99:59:59,999 with the military, 118 99:59:59,999 --> 99:59:59,999 taking advantage of the military's ability to move fast, do logistics 119 99:59:59,999 --> 99:59:59,999 and secure areas. 120 99:59:59,999 --> 99:59:59,999 We need to do simulations: germs games, not war games, 121 99:59:59,999 --> 99:59:59,999 so that we see where the holes are. 122 99:59:59,999 --> 99:59:59,999 The last time a germ game was done in the United States 123 99:59:59,999 --> 99:59:59,999 was back in 2001, and it didn't go so well. 124 99:59:59,999 --> 99:59:59,999 So far the score is germs: 1, people: 0. 125 99:59:59,999 --> 99:59:59,999 Finally, we need lots of advanced R&D in areas of vaccines and diagnostics. 126 99:59:59,999 --> 99:59:59,999 There are some big breakthroughs, like the Adeno-associated virus, 127 99:59:59,999 --> 99:59:59,999 that could work very, very quickly. 128 99:59:59,999 --> 99:59:59,999 Now I don't have an exact budget for what this would cost, 129 99:59:59,999 --> 99:59:59,999 but I'm quite sure that it's very modest compared to the potential harm. 130 99:59:59,999 --> 99:59:59,999 The World Bank estimates that if we have a worldwide flu epidemic, 131 99:59:59,999 --> 99:59:59,999 global wealth would go down by over 3 trillion dollars. 132 99:59:59,999 --> 99:59:59,999 We'd have millions and millions of deaths. 133 99:59:59,999 --> 99:59:59,999 These investments offer significant benefits beyond just 134 99:59:59,999 --> 99:59:59,999 being ready for an epidemic. 135 99:59:59,999 --> 99:59:59,999 The primary healthcare, the R&D, those things 136 99:59:59,999 --> 99:59:59,999 would reduce global health equity and make the world more just, 137 99:59:59,999 --> 99:59:59,999 as well as more safe. 138 99:59:59,999 --> 99:59:59,999 So I think this should absolutely be a priority. 139 99:59:59,999 --> 99:59:59,999 There's no need to panic. 140 99:59:59,999 --> 99:59:59,999 We don't have