0:00:06.383,0:00:11.110 You have about 20,000 genes in your DNA. 0:00:11.110,0:00:13.950 They encode the molecules that[br]make up your body, 0:00:13.958,0:00:17.990 from the keratin in your toenails,[br]to the collagen at the tip of your nose, 0:00:17.990,0:00:21.287 to the dopamine surging around[br]inside your brain. 0:00:21.287,0:00:23.678 Other species have genes of their own. 0:00:23.678,0:00:26.094 A spider has genes for spider silk. 0:00:26.094,0:00:30.808 An oak tree has genes for chlorophyll,[br]which turns sunlight into wood. 0:00:30.808,0:00:33.332 So where did all those genes come from?[br] 0:00:33.332,0:00:35.225 It depends on the gene. 0:00:35.225,0:00:40.254 Scientists suspect that life[br]started on Earth about 4 billion years ago. 0:00:40.254,0:00:42.741 The early life forms were[br]primitive microbes 0:00:42.741,0:00:47.380 with a basic set of genes for[br]the basic tasks required to stay alive. 0:00:47.380,0:00:50.175 They passed down those basic genes[br]to their offspring 0:00:50.175,0:00:52.321 through billions of generations. 0:00:52.321,0:00:57.955 Some of them still do the same jobs[br]in our cells today, like copying DNA. 0:00:57.955,0:01:01.942 But none of those microbes had genes[br]for spider silk or dopamine. 0:01:01.942,0:01:06.689 There are a lot more genes on Earth today[br]than there were back then. 0:01:06.689,0:01:11.468 It turns out that a lot of those[br]extra genes were born from mistakes. 0:01:11.468,0:01:15.605 Each time a cell divides,[br]it makes new copies of its DNA. 0:01:15.605,0:01:20.167 Sometimes it accidentally copies[br]the same stretch of DNA twice. 0:01:20.167,0:01:24.592 In the process, it may make an extra copy[br]of one of its genes. 0:01:24.592,0:01:27.818 At first, the extra gene works the same[br]as the original one. 0:01:27.818,0:01:32.054 But over the generations, [br]it may pick up new mutations. 0:01:32.054,0:01:35.394 Those mutations may change how[br]the new gene works, 0:01:35.394,0:01:38.144 and that new gene may duplicate again. 0:01:38.144,0:01:41.947 A surprising number of our [br]mutated genes emerged more recently; 0:01:41.947,0:01:45.035 many in just the past few million years. 0:01:45.035,0:01:50.055 The youngest evolved after our own species[br]broke off from our cousins, the apes. 0:01:50.055,0:01:54.148 While it may take over a million years[br]for a single gene to give rise 0:01:54.148,0:01:55.905 to a whole family of genes, 0:01:55.905,0:01:58.872 scientists are finding that once [br]the new genes evolve, 0:01:58.872,0:02:01.695 they can quickly take on[br]essential functions. 0:02:01.695,0:02:06.405 For example, we have hundreds of genes[br]for the proteins in our noses 0:02:06.405,0:02:08.647 that grab odor molecules. 0:02:08.647,0:02:11.298 The mutations let them grab[br]different molecules, 0:02:11.298,0:02:14.951 giving us the power to perceive trillions[br]of different smells. 0:02:14.951,0:02:19.383 Sometimes mutations have[br]a bigger effect on new copies of genes. 0:02:19.383,0:02:22.913 They may cause a gene to make its[br]protein in a different organ, 0:02:22.913,0:02:25.446 or at a different time of life, 0:02:25.446,0:02:29.175 or the protein may start doing[br]a different job altogether. 0:02:29.175,0:02:33.640 In snakes, for example, there's a gene[br]that makes a protein for killing bacteria. 0:02:33.640,0:02:38.243 Long ago, the gene duplicated[br]and the new copy mutated. 0:02:38.243,0:02:40.957 That mutation changed[br]the signal in the gene 0:02:40.957,0:02:43.199 about where it should make its protein. 0:02:43.199,0:02:45.800 Instead of becoming active in[br]the snake's pacreas, 0:02:45.800,0:02:50.569 it started making this bacteria-killing[br]protein in the snake's mouth. 0:02:50.569,0:02:55.048 So when the snake bit its prey,[br]this enzyme got into the animal's wound. 0:02:55.048,0:02:57.949 And when this protein proved[br]to have a harmful effect, 0:02:57.949,0:03:00.060 and helped the snake catch more prey, 0:03:00.060,0:03:01.922 it became favored. 0:03:01.922,0:03:05.733 So now what was a gene in the pancreas[br]makes a venom in the mouth 0:03:05.733,0:03:07.779 that kills the snake's prey. 0:03:07.779,0:03:10.990 And there are even more incredible ways[br]to make a new gene. 0:03:10.990,0:03:13.883 The DNA of animals and plants[br]and other species 0:03:13.883,0:03:18.197 contain huge stretches without any[br]protein coding genes. 0:03:18.197,0:03:22.053 As far as scientists can tell,[br]its mostly random sequences 0:03:22.053,0:03:24.676 of genetic giberish that serve[br]no function. 0:03:24.676,0:03:28.704 These stretches of DNA[br]sometimes mutate, just like genes do. 0:03:28.704,0:03:31.821 Sometimes those mutations[br]turn the DNA into a place 0:03:31.821,0:03:34.307 where a cell can start reading it. 0:03:34.307,0:03:36.977 Suddenly the cell is making a new protein. 0:03:36.977,0:03:40.515 At first, the protein may be useless,[br]or even harmful, 0:03:40.515,0:03:43.913 but more mutations can [br]change the shape of the protein. 0:03:43.913,0:03:45.999 The protein may start[br]doing something useful, 0:03:45.999,0:03:48.616 something that makes an organism[br]healthier, stronger, 0:03:48.616,0:03:50.941 better able to reproduce. 0:03:50.941,0:03:55.233 Scientists have found these new genes[br]at work in many parts of animal bodies. 0:03:55.233,0:03:58.643 So our 20,000 genes have many origins, 0:03:58.643,0:04:03.577 from the origin of life, to new genes[br]still coming into existence from scratch. 0:04:03.577,0:04:07.196 As long as life is here on Earth,[br]it will be making new genes.