0:00:14.392,0:00:25.019 You have about 20,000 genes in your DNA. 9:59:59.000,9:59:59.000 They encode the molecules that[br]make up your body, 9:59:59.000,9:59:59.000 from the keratin in your toenails,[br]to the collagen at the tip of your nose, 9:59:59.000,9:59:59.000 to the dopamine surging around[br]inside your brain. 9:59:59.000,9:59:59.000 Other species have genes of their own. 9:59:59.000,9:59:59.000 A spider has genes for spider silk. 9:59:59.000,9:59:59.000 An oak tree has genes for chlorophyll,[br]which turns sunlight into wood. 9:59:59.000,9:59:59.000 So where did all those genes come from?[br] 9:59:59.000,9:59:59.000 It depends on the gene. 9:59:59.000,9:59:59.000 Scientists suspect that life[br]started on Earth about 4 billion years ago. 9:59:59.000,9:59:59.000 The early life forms were[br]primitive microbes 9:59:59.000,9:59:59.000 with a basic set of genes for[br]the basic tasks required to stay alive. 9:59:59.000,9:59:59.000 They passed down those basic genes[br]to their offspring 9:59:59.000,9:59:59.000 through billions of generations. 9:59:59.000,9:59:59.000 Some of them still do the same jobs[br]in our cells today, like copying DNA. 9:59:59.000,9:59:59.000 But none of those microbes had genes[br]for spider silk or dopamine. 9:59:59.000,9:59:59.000 There are a lot more genes on Earth today[br]than there were back then. 9:59:59.000,9:59:59.000 It turns out that a lot of those[br]extra genes were born from mistakes. 9:59:59.000,9:59:59.000 Each time a cell divides,[br]it makes new copies of its DNA. 9:59:59.000,9:59:59.000 Sometimes it accidentally copies[br]the same stretch of DNA twice. 9:59:59.000,9:59:59.000 In the process, it may make an extra copy[br]of one of its genes. 9:59:59.000,9:59:59.000 At first, the extra gene works the same[br]as the original one. 9:59:59.000,9:59:59.000 But over the generations, [br]it may pick up new mutations. 9:59:59.000,9:59:59.000 Those mutations may change how[br]the new gene works, 9:59:59.000,9:59:59.000 and that new gene may duplicate again. 9:59:59.000,9:59:59.000 A surprising number of our [br]mutated genes emerged more recently; 9:59:59.000,9:59:59.000 Many in just the past few million years. 9:59:59.000,9:59:59.000 The youngest evolved after our own species[br]broke off from our cousins, the apes. 9:59:59.000,9:59:59.000 While it may take over a million years[br]for a single gene to give rise 9:59:59.000,9:59:59.000 to a whole family of genes, 9:59:59.000,9:59:59.000 scientists are finding that once [br]the new genes evolve, 9:59:59.000,9:59:59.000 they can quickly take on[br]essential functions. 9:59:59.000,9:59:59.000 For example, we have hundreds of genes[br]for the proteins in our noses 9:59:59.000,9:59:59.000 that grab odor molecules. 9:59:59.000,9:59:59.000 The mutations let them grab[br]different molecules, 9:59:59.000,9:59:59.000 giving us the power to perceive trillions[br]of different smells. 9:59:59.000,9:59:59.000 Sometimes mutations have[br]a bigger effect on new copies of genes. 9:59:59.000,9:59:59.000 They may cause a gene to make its[br]protein in a different organ, 9:59:59.000,9:59:59.000 or at a different time of life, 9:59:59.000,9:59:59.000 or the protein may start doing[br]a different job altogether. 9:59:59.000,9:59:59.000 In snakes, for example, there's a gene[br]that makes a protein for killing bacteria. 9:59:59.000,9:59:59.000 Long ago, the gene duplicated[br]and the new copy mutated. 9:59:59.000,9:59:59.000 That mutation changed[br]the signal in the gene 9:59:59.000,9:59:59.000 about where it should make its protein. 9:59:59.000,9:59:59.000 Instead of becoming active in[br]the snake's pacreas, 9:59:59.000,9:59:59.000 it started making this bacteria-killing[br]protein in the snake's mouth. 9:59:59.000,9:59:59.000 So when the snake bit its prey,[br]this enzyme got into the animal's wound. 9:59:59.000,9:59:59.000 And when this protein proved[br]to have a harmful effect, 9:59:59.000,9:59:59.000 and helped the snake catch more prey, 9:59:59.000,9:59:59.000 it became favored, 9:59:59.000,9:59:59.000 so now what was a gene in the pancreas[br]makes a venom in the mouth 9:59:59.000,9:59:59.000 that kills the snake's prey. 9:59:59.000,9:59:59.000 And there are even more incredible ways[br]to make a new gene. 9:59:59.000,9:59:59.000 The DNA of animals and plants[br]and other species 9:59:59.000,9:59:59.000 contain huge stretches without any[br]protein coding genes. 9:59:59.000,9:59:59.000 As far as scientists can tell,[br]its mostly random sequences 9:59:59.000,9:59:59.000 of genetic giberish that serve[br]no function. 9:59:59.000,9:59:59.000 These stretches of DNA[br]sometimes mutate, just like genes do. 9:59:59.000,9:59:59.000 Sometimes those mutations[br]turn the DNA into a place 9:59:59.000,9:59:59.000 where a cell cans start reading it. 9:59:59.000,9:59:59.000 Suddenly the cell is making a new protein. 9:59:59.000,9:59:59.000 At first, the protein may be useless,[br]or even harmful, 9:59:59.000,9:59:59.000 but more mutations can [br]change the shape of the protein. 9:59:59.000,9:59:59.000 The protein may start[br]doing something useful, 9:59:59.000,9:59:59.000 something that makes an organism[br]healthier, stronger, 9:59:59.000,9:59:59.000 better able to reproduce. 9:59:59.000,9:59:59.000 Scientists have found these new genes[br]at work in many parts of animal bodies. 9:59:59.000,9:59:59.000 So our 20,000 genes have many origins, 9:59:59.000,9:59:59.000 from the origin of life, to new genes[br]still coming into existence from scratch. 9:59:59.000,9:59:59.000 As long as life is here on Earth,[br]it will be making new genes.