WEBVTT 00:00:08.243 --> 00:00:12.673 The biggest kidney stone on record weighed more than a kilogram 00:00:12.673 --> 00:00:16.765 and was 17 centimeters in diameter. 00:00:16.765 --> 00:00:20.643 The patient didn't actually swallow a stone the size of a coconut. 00:00:20.643 --> 00:00:23.464 Kidney stones form inside the body, 00:00:23.464 --> 00:00:28.704 but unfortunately, they're extremely painful to get out. 00:00:28.704 --> 00:00:33.245 A kidney stone is a hard mass of crystals that can form in the kidneys, 00:00:33.245 --> 00:00:34.345 ureters, 00:00:34.345 --> 00:00:35.254 bladder, 00:00:35.254 --> 00:00:36.846 or urethra. 00:00:36.846 --> 00:00:39.595 Urine contains compounds that consist of calcium, 00:00:39.595 --> 00:00:40.485 sodium, 00:00:40.485 --> 00:00:41.387 potassium, 00:00:41.387 --> 00:00:42.406 oxalate, 00:00:42.406 --> 00:00:43.476 uric acid, 00:00:43.476 --> 00:00:45.487 and phosphate. 00:00:45.487 --> 00:00:48.327 If the levels of these particles get too high, 00:00:48.327 --> 00:00:51.275 or if urine becomes too acidic or basic, 00:00:51.275 --> 00:00:56.635 the particles can clump together and crystallize. 00:00:56.635 --> 00:00:58.316 Unless the problem is addressed, 00:00:58.316 --> 00:01:03.907 the crystals will gradually grow over a few weeks, months, or even years, 00:01:03.907 --> 00:01:08.116 forming a detectable stone. 00:01:08.116 --> 00:01:12.214 Calcium oxalate is the most common type of crystal to form this way, 00:01:12.214 --> 00:01:16.657 and accounts for about 80% of kidney stones. 00:01:16.657 --> 00:01:21.938 Less common kidney stones are made of calcium phosphate, or uric acid. 00:01:21.938 --> 00:01:23.777 A slightly different type of stone 00:01:23.777 --> 00:01:27.528 made of the minerals magnesium ammonium phosphate, or struvite, 00:01:27.528 --> 00:01:31.258 can be caused by bacterial infection. 00:01:31.258 --> 00:01:35.169 And even rarer stones can result from genetic disorders 00:01:35.169 --> 00:01:38.489 or certain medications. 00:01:38.489 --> 00:01:44.099 A kidney stone can go undetected until it starts to move. 00:01:44.099 --> 00:01:47.428 When a stone travels through the kidney and into the ureter, 00:01:47.428 --> 00:01:52.469 its sharp edges scratch the walls of the urinary tract. 00:01:52.469 --> 00:01:57.481 Nerve endings embedded in this tissue transmit excruciating pain signals 00:01:57.481 --> 00:01:59.802 through the nervous system. 00:01:59.802 --> 00:02:04.142 And the scratches can send blood flowing into the urine. 00:02:04.142 --> 00:02:06.892 This can be accompanied by symptoms of nausea, 00:02:06.892 --> 00:02:07.734 vomiting, 00:02:07.734 --> 00:02:11.144 and a burning sensation while urinating. 00:02:11.144 --> 00:02:14.594 If a stone gets big enough to actually block the flow of urine, 00:02:14.594 --> 00:02:17.472 it can create an infection, or back flow, 00:02:17.472 --> 00:02:21.253 and damage the kidneys themselves. 00:02:21.253 --> 00:02:24.124 But most kidney stones don't become this serious, 00:02:24.124 --> 00:02:27.353 or even require invasive treatment. 00:02:27.353 --> 00:02:30.157 Masses less than five millimeters in diameter 00:02:30.157 --> 00:02:33.685 will usually pass out of the body on their own. 00:02:33.685 --> 00:02:37.415 A doctor will often simply recommend drinking large amounts of water 00:02:37.415 --> 00:02:39.895 to help speed the process along, 00:02:39.895 --> 00:02:43.385 and maybe taking some pain killers. 00:02:43.385 --> 00:02:47.165 If the stone is slightly larger, medications like alpha blockers 00:02:47.165 --> 00:02:50.326 can help by relaxing the muscles in the ureter 00:02:50.326 --> 00:02:54.126 and making it easier for the stone to get through. 00:02:54.126 --> 00:02:56.406 Another medication called potassium citrate 00:02:56.406 --> 00:03:02.987 can help dissolve the stones by creating a less acidic urine. 00:03:02.987 --> 00:03:06.197 For medium-sized stones up to about ten millimeters, 00:03:06.197 --> 00:03:10.577 one option is pulverizing them with soundwaves. 00:03:10.577 --> 00:03:16.226 Extracorporeal shock wave lithotripsy uses high-intensity pulses 00:03:16.226 --> 00:03:21.708 of focused ultrasonic energy aimed directly at the stone. 00:03:21.708 --> 00:03:25.369 The pulses create vibrations inside the stone itself 00:03:25.369 --> 00:03:29.149 and small bubbles jostle it. 00:03:29.149 --> 00:03:33.127 These combined forces crush the stone into smaller pieces 00:03:33.127 --> 00:03:37.389 that can pass out of the body more easily. 00:03:37.389 --> 00:03:40.108 But zapping a stone with sound doesn't work as well 00:03:40.108 --> 00:03:42.565 if it's simply too big. 00:03:42.565 --> 00:03:47.050 So sometimes, more invasive treatments are necessary. 00:03:47.050 --> 00:03:53.071 A rigid tube called a stent can be placed in the ureter to expand it. 00:03:53.071 --> 00:03:57.550 Optical fibers can deliver laser pulses to break up the stone. 00:03:57.550 --> 00:04:00.980 Stones can also be surgically removed through an incision 00:04:00.980 --> 00:04:04.489 in the patient's back or groin. 00:04:04.489 --> 00:04:07.901 What about just avoiding kidney stones in the first place? 00:04:07.901 --> 00:04:09.821 For people prone to them, 00:04:09.821 --> 00:04:12.470 their doctor may recommend drinking plenty of water, 00:04:12.470 --> 00:04:15.651 which dilutes the calcium oxalate and other compounds 00:04:15.651 --> 00:04:20.615 that eventually build up into painful stones. 00:04:20.615 --> 00:04:21.878 Foods like potato chips, 00:04:21.878 --> 00:04:22.932 spinach, 00:04:22.932 --> 00:04:23.744 rhubarb, 00:04:23.744 --> 00:04:26.280 and beets are high in oxalate, 00:04:26.280 --> 00:04:29.847 so doctors might advise limiting them. 00:04:29.847 --> 00:04:32.432 Even though calcium is often found in stones, 00:04:32.432 --> 00:04:36.281 calcium in foods and beverages can actually help 00:04:36.281 --> 00:04:39.101 by binding to oxalate in the digestive tract 00:04:39.101 --> 00:04:43.143 before it can be absorbed and reach the kidneys. 00:04:43.143 --> 00:04:46.222 If you do end up with a kidney stone, you're not alone. 00:04:46.222 --> 00:04:48.913 Data suggests that rates are rising, 00:04:48.913 --> 00:04:52.852 but that world record probably won't be broken any time soon.