WEBVTT 00:00:01.161 --> 00:00:03.361 Antibodies are proteins that play an 00:00:03.474 --> 00:00:05.824 integral role in the complex system of 00:00:05.983 --> 00:00:08.293 specific immunity. They bind to and 00:00:08.571 --> 00:00:10.681 inactivate foreign proteins called 00:00:10.939 --> 00:00:13.429 antigens. Each type of antibody binds to 00:00:13.570 --> 00:00:17.480 one kind of antigen molecule. B-cells are 00:00:17.617 --> 00:00:19.797 one of the two types of white blood 00:00:19.872 --> 00:00:23.872 cells that make antibodies. When a 00:00:24.221 --> 00:00:27.101 bacterial cell enters the bloodstream, 00:00:27.160 --> 00:00:29.800 proteins on its surface act as antigens 00:00:29.890 --> 00:00:32.260 and trigger a response by the immune 00:00:32.397 --> 00:00:34.877 system. These antigens will bind to the 00:00:34.929 --> 00:00:36.729 unique B cells that have the 00:00:36.820 --> 00:00:38.980 corresponding antibodies on their 00:00:39.067 --> 00:00:41.247 surfaces. These B cells now divide. 00:00:44.124 --> 00:00:46.724 Some continue to divide producing many 00:00:46.884 --> 00:00:50.030 plasma cells. Plasma cells secrete large 00:00:50.069 --> 00:00:52.309 quantities of antibodies into the 00:00:52.373 --> 00:00:54.713 bloodstream. This division of only the 00:00:54.785 --> 00:00:58.085 appropriate B cells is called clonal 00:00:58.085 --> 00:00:59.130 selection.