1 00:00:01,161 --> 00:00:03,361 Antibodies are proteins that play an 2 00:00:03,474 --> 00:00:05,824 integral role in the complex system of 3 00:00:05,983 --> 00:00:08,293 specific immunity. They bind to and 4 00:00:08,571 --> 00:00:10,681 inactivate foreign proteins called 5 00:00:10,939 --> 00:00:13,429 antigens. Each type of antibody binds to 6 00:00:13,570 --> 00:00:17,480 one kind of antigen molecule. B-cells are 7 00:00:17,617 --> 00:00:19,797 one of the two types of white blood 8 00:00:19,872 --> 00:00:23,872 cells that make antibodies. When a 9 00:00:24,221 --> 00:00:27,101 bacterial cell enters the bloodstream, 10 00:00:27,160 --> 00:00:29,800 proteins on its surface act as antigens 11 00:00:29,890 --> 00:00:32,260 and trigger a response by the immune 12 00:00:32,397 --> 00:00:34,877 system. These antigens will bind to the 13 00:00:34,929 --> 00:00:36,729 unique B cells that have the 14 00:00:36,820 --> 00:00:38,980 corresponding antibodies on their 15 00:00:39,067 --> 00:00:41,247 surfaces. These B cells now divide. 16 00:00:44,124 --> 00:00:46,724 Some continue to divide producing many 17 00:00:46,884 --> 00:00:50,030 plasma cells. Plasma cells secrete large 18 00:00:50,069 --> 00:00:52,309 quantities of antibodies into the 19 00:00:52,373 --> 00:00:54,713 bloodstream. This division of only the 20 00:00:54,785 --> 00:00:58,085 appropriate B cells is called clonal 21 00:00:58,085 --> 00:00:59,130 selection.