0:00:01.161,0:00:03.361 Antibodies are proteins that play an 0:00:03.474,0:00:05.824 integral role in the complex system of 0:00:05.983,0:00:08.293 specific immunity. They bind to and 0:00:08.571,0:00:10.681 inactivate foreign proteins called 0:00:10.939,0:00:13.429 antigens. Each type of antibody binds to 0:00:13.570,0:00:17.480 one kind of antigen molecule. B-cells are 0:00:17.617,0:00:19.797 one of the two types of white blood 0:00:19.872,0:00:23.872 cells that make antibodies. When a 0:00:24.221,0:00:27.101 bacterial cell enters the bloodstream, 0:00:27.160,0:00:29.800 proteins on its surface act as antigens 0:00:29.890,0:00:32.260 and trigger a response by the immune 0:00:32.397,0:00:34.877 system. These antigens will bind to the 0:00:34.929,0:00:36.729 unique B cells that have the 0:00:36.820,0:00:38.980 corresponding antibodies on their 0:00:39.067,0:00:41.247 surfaces. These B cells now divide. 0:00:44.124,0:00:46.724 Some continue to divide producing many 0:00:46.884,0:00:50.030 plasma cells. Plasma cells secrete large 0:00:50.069,0:00:52.309 quantities of antibodies into the 0:00:52.373,0:00:54.713 bloodstream. This division of only the 0:00:54.785,0:00:58.085 appropriate B cells is called clonal 0:00:58.085,0:00:59.130 selection.