WEBVTT 00:00:01.000 --> 00:00:04.000 (English captions by Trisha Paul, University of Michigan.) 00:00:04.000 --> 00:00:08.000 Introduction to Epi-zoonotic Diseases. 00:00:09.000 --> 00:00:15.000 In this session, we shall look at key terminologies and definitions related to zoonotic diseases 00:00:16.000 --> 00:00:19.000 of epidemic potential. 00:00:19.000 --> 00:00:25.000 We shall look at the zoonotic diseases of epidemic potential in Eastern Africa, the 00:00:25.000 --> 00:00:31.000 significance of epi-zoonotics as emerging diseases, the factors promoting emergence 00:00:31.000 --> 00:00:38.000 of epi-zoonotic diseases, the consequences of epi-zoonotic diseases, and general response 00:00:38.000 --> 00:00:45.000 interventions, and then, issues related to animal welfare. 00:00:45.000 --> 00:00:52.000 A zoonosis is a disease or infection which is naturally transmitted between animals and 00:00:52.000 --> 00:00:54.000 humans. 00:00:54.000 --> 00:01:01.000 It may occur from an animal to human, or from human to an animal. 00:01:01.000 --> 00:01:10.000 A simpler definition is a disease that normally infects animals, but can also infect humans. 00:01:10.000 --> 00:01:19.000 An epizootic disease is an outbreak (epidemic) of disease in an animal population. 00:01:19.000 --> 00:01:27.000 An enzootic is a disease that is endemic in animals. 00:01:27.000 --> 00:01:33.000 Exotic diseases are those which are imported into a country in which they do not otherwise 00:01:33.000 --> 00:01:34.000 occur. 00:01:34.000 --> 00:01:40.000 An example is avian influenza. 00:01:40.000 --> 00:01:46.000 Emerging and re-emerging zoonoses are diseases caused either by totally new or partially 00:01:46.000 --> 00:01:55.000 new agents, or by micro-organisms previously known, but now occurring in places or in species 00:01:55.000 --> 00:01:59.000 where the disease was previously unknown. 00:01:59.000 --> 00:02:04.000 Examples of this include influenza, ebola, and SARS. 00:02:04.000 --> 00:02:12.000 The priority of zoonotic diseases of epidemic potential in Eastern Africa include rift valley 00:02:12.000 --> 00:02:21.000 fever, influenza A viruses, anthrax, rabies, ebola and other viral hemorrhaegic fevers, 00:02:21.000 --> 00:02:26.000 plague, and trypanosomiasis. 00:02:26.000 --> 00:02:32.000 What is the significance of epi-zoonotics as emerging diseases, especially in Eastern 00:02:32.000 --> 00:02:33.000 Africa? 00:02:33.000 --> 00:02:39.000 Globally, there have been over 20 new diseases in the last 30 years. 00:02:39.000 --> 00:02:45.000 Over 2/3 of new disease causing agents arise from wild-life. 00:02:45.000 --> 00:02:52.000 Examples include SARS, nipah, H5N1, H1N1. 00:02:52.000 --> 00:02:58.000 Domestic animals account for 20% of new zoonoses. 00:02:58.000 --> 00:03:07.000 The East and Central Africa Region is a 'hot spot' for new diseases. 00:03:07.000 --> 00:03:13.000 Factors promoting the emergence of epidemic-prone epi-zoonotic diseases include socio-economic 00:03:13.000 --> 00:03:23.000 factors like intensive farming without bio-security measures, water-supply projects, urbanization, 00:03:23.000 --> 00:03:31.000 human population movement, animal movement, famine, free-range farming systems. 00:03:31.000 --> 00:03:37.000 Environmental factors include climate change (e.g. global warming) and presence of vectors 00:03:37.000 --> 00:03:44.000 and/or reservoirs. 00:03:44.000 --> 00:03:50.000 Human-related factors include co-infection with other diseases agents (like HIV and tuberculosis or TB), 00:03:50.000 --> 00:03:57.000 lack of knowledge on bio-security measures, inadequate personal hygiene like sneezing 00:03:57.000 --> 00:04:02.000 without covering mouth or not washing hands. 00:04:02.000 --> 00:04:09.000 Cultural and behavioural risk factors include lack of knowledge, food habits, changes in 00:04:09.000 --> 00:04:15.000 life-style, human-livestock-wildlife interaction. 00:04:15.000 --> 00:04:22.000 These are some of the characteristics of the human-animal interface that increases the 00:04:22.000 --> 00:04:29.000 likelihood of transferring diseases that were previously not known in humans from animals. 00:04:29.000 --> 00:04:37.000 Intense handling of animal products with low bio-security causing diseases like brucellosis, 00:04:37.000 --> 00:04:41.000 anthrax, avian influenza. 00:04:41.000 --> 00:04:49.000 Pastoralism and free-range systems, hunting, gathering, eating game meat and carcasses 00:04:49.000 --> 00:04:54.000 predisposing to ebola and anthrax. 00:04:54.000 --> 00:04:59.000 Contact with bats predisposing to ebola and marburg. 00:04:59.000 --> 00:05:06.000 Ill cooked products causing salmonellosis and brucellosis. 00:05:06.000 --> 00:05:13.000 Hygiene and rats predisposing to leptospirosis and hepatitis E. 00:05:13.000 --> 00:05:20.000 Free-range poultry and migratory birds predisposing to avion influenza. 00:05:20.000 --> 00:05:29.000 Conservation areas like Ngorongoro and Samburu. Ill-handling of domestic canines predisposing 00:05:29.000 --> 00:05:31.000 to rabies. 00:05:31.000 --> 00:05:39.000 Socio-cultural factors including sharing accommodation with animals, and cross-border risk as well 00:05:39.000 --> 00:05:44.000 as gender related risk 00:05:44.000 --> 00:05:51.000 What are the consequences of epidemic-prone epi-zoonotic diseases? 00:05:51.000 --> 00:05:55.000 They include: 00:05:55.000 --> 00:06:02.000 Socio-economic impacts like reduction in the level of outputs from animal production, reduction 00:06:02.000 --> 00:06:09.000 in perceived or actual output quality, waste of inputs to animal production, resource costs 00:06:09.000 --> 00:06:16.000 of disease prevention and control, negative animal welfare effects, and international 00:06:16.000 --> 00:06:20.000 trade restrictions. 00:06:20.000 --> 00:06:31.000 Human health costs including effects or costs of treatment, effects on the environment, 00:06:31.000 --> 00:06:37.000 effects on tourism, effects on rural livelihoods, political and social disruption, and increased 00:06:37.000 --> 00:06:39.000 poverty. 00:06:39.000 --> 00:06:46.000 All the public health consequences of epi-zoonoses include increased deaths, increased illness, 00:06:46.000 --> 00:06:53.000 social disruption and panic, collapse of regular heath care systems, health workers are at 00:06:53.000 --> 00:07:02.000 high-risk of contracting the diseases, and health workers may run away from health units. 00:07:02.000 --> 00:07:09.000 Response interventions include farmers should report incidents to animal and human health 00:07:09.000 --> 00:07:18.000 workers, provisional quarantine of affected areas if necessary, confirming the occurrence 00:07:18.000 --> 00:07:24.000 of an outbreak and notifying authorities 00:07:24.000 --> 00:07:31.000 Activating the Rapid Response Team including vets, health workers, leaders, and police, 00:07:31.000 --> 00:07:40.000 etc), identifying source of infection and identifying the severity of the infection 00:07:40.000 --> 00:07:47.000 and extent of spread, setting up immediate control measures 00:07:47.000 --> 00:07:54.000 Disposing of dead animals in safe ways, either by burning them or burying them, quarantining 00:07:54.000 --> 00:08:02.000 the sick and suspected and observing general conditions, stopping movement of animals, 00:08:02.000 --> 00:08:07.000 and vaccination where necessary. 00:08:07.000 --> 00:08:16.000 In outbreak situations of epi-zoonotic diseases, animal welfare situations should be taken into consideration. 00:08:16.000 --> 00:08:25.000 If they are to be destroyed or killed, animals should be treated in a humane manner. 00:08:25.000 --> 00:08:27.000 Reduce undue pain. 00:08:27.000 --> 00:08:31.000 Confine them in a considerate manner. 00:08:31.000 --> 00:08:35.000 Thanks for listening.