WEBVTT 00:00:00.220 --> 00:00:01.803 - [Instructor] Now let's take a look 00:00:01.803 --> 00:00:05.053 at Generalized Anxiety Disorder or GAD. 00:00:06.017 --> 00:00:08.164 And this disorder is characterized 00:00:08.164 --> 00:00:12.440 by excessive anxiety under most circumstances 00:00:12.440 --> 00:00:15.523 and worry about practically anything. 00:00:16.448 --> 00:00:19.444 GADs sometimes is what is also referred to 00:00:19.444 --> 00:00:21.527 as free-floating anxiety. 00:00:24.325 --> 00:00:28.320 It usually first appears in childhood or adolescence 00:00:28.320 --> 00:00:32.946 and in fact it is quite common in the Western society. 00:00:32.946 --> 00:00:35.740 Women tend to be diagnosed more than men 00:00:35.740 --> 00:00:38.414 by about a ratio of two to one. 00:00:38.414 --> 00:00:42.581 And about 1/4 of people who are diagnosed with this 00:00:43.539 --> 00:00:46.380 are currently in treatment. 00:00:46.380 --> 00:00:47.797 And there you see 00:00:48.842 --> 00:00:52.425 the characteristics for GAD from the DSM-5. 00:00:53.682 --> 00:00:56.142 For six months and more, the person experiences 00:00:56.142 --> 00:00:59.183 disproportionate, uncontrollable, 00:00:59.183 --> 00:01:03.945 and ongoing anxiety and worry about multiple matters. 00:01:03.945 --> 00:01:07.230 The symptoms include at least three of the following. 00:01:07.230 --> 00:01:11.397 Edginess, fatigue, poor concentration, irritability, 00:01:12.460 --> 00:01:15.235 muscle tension, and sleep problems. 00:01:15.235 --> 00:01:18.236 And there's significant distress or impairment 00:01:18.236 --> 00:01:20.175 with the disorder. 00:01:20.175 --> 00:01:21.675 And we know that there are a variety 00:01:21.675 --> 00:01:25.842 of theoretical explanations to explain Generalized Anxiety, 00:01:27.288 --> 00:01:31.183 so let's take a look at those theoretical explanations. 00:01:31.183 --> 00:01:34.968 The first is the socio-cultural perspective, 00:01:34.968 --> 00:01:36.075 which basically focuses 00:01:36.075 --> 00:01:39.242 on societal and multicultural factors. 00:01:41.242 --> 00:01:45.049 For this perspective, GAD is most likely to develop 00:01:45.049 --> 00:01:47.987 in people faced with social conditions 00:01:47.987 --> 00:01:50.070 that are truly dangerous. 00:01:51.221 --> 00:01:54.054 Research supports this theory. 00:01:54.054 --> 00:01:57.102 For example, when you take a look at situations like 00:01:57.102 --> 00:02:01.667 nuclear disaster, the Three Mile Island in 1979, 00:02:01.667 --> 00:02:05.834 Hurricane Katrina in 2005, the Haiti Earthquake in 2010, 00:02:08.425 --> 00:02:13.040 we've found significantly higher rates of GAD. 00:02:13.040 --> 00:02:16.645 A lot of the most powerful forms of societal stress 00:02:16.645 --> 00:02:20.514 is poverty, and we find that those individuals 00:02:20.514 --> 00:02:25.147 who face less equality, less power, greater vulnerability, 00:02:25.147 --> 00:02:28.558 rundown communities, higher crime rates, 00:02:28.558 --> 00:02:31.669 fewer educational and job opportunities, 00:02:31.669 --> 00:02:35.836 are definitely at a greater risk for health problems. 00:02:36.812 --> 00:02:39.666 And as would be predicted by this model then, 00:02:39.666 --> 00:02:42.273 rates of GAD are generally higher 00:02:42.273 --> 00:02:45.741 in lower socio-academic status groups. 00:02:45.741 --> 00:02:48.801 However, while the poverty and other social pressures 00:02:48.801 --> 00:02:51.371 may create a climate for GAD, 00:02:51.371 --> 00:02:54.831 other factors are clearly at work. 00:02:54.831 --> 00:02:56.288 And we find that quite honestly, 00:02:56.288 --> 00:02:59.182 most people who're living in dangerous environments 00:02:59.182 --> 00:03:01.958 don't actually develop GAD, 00:03:01.958 --> 00:03:04.306 and other models will attempt to explain then 00:03:04.306 --> 00:03:08.473 why some people develop the disorder and others do not, 00:03:09.922 --> 00:03:14.089 such as this perspective, the psychodynamic perspective. 00:03:15.036 --> 00:03:16.896 The psychodynamic perspective believe 00:03:16.896 --> 00:03:19.902 that all children experience anxiety 00:03:19.902 --> 00:03:24.094 and use defense mechanisms to help control it. 00:03:24.094 --> 00:03:28.615 Realistic anxiety results from actual danger. 00:03:28.615 --> 00:03:31.286 Neurotic anxiety, though, results when children 00:03:31.286 --> 00:03:35.286 are prevented from expressing their id impulses. 00:03:36.916 --> 00:03:40.471 So Freud believes then, that excessive childhood neurotic 00:03:40.471 --> 00:03:43.721 or moral anxiety set the stage for GAD. 00:03:44.955 --> 00:03:48.142 Contemporary theorists, however, often disagree 00:03:48.142 --> 00:03:51.768 with very specific aspects of Freud's explanation, 00:03:51.768 --> 00:03:54.338 though most continue to believe that the disorder 00:03:54.338 --> 00:03:58.505 can be traced to an adequate parent-child relationships. 00:04:00.675 --> 00:04:03.184 So when we take a look at the techniques 00:04:03.184 --> 00:04:06.307 that are used or the therapies, 00:04:06.307 --> 00:04:09.024 in general they use the same general techniques 00:04:09.024 --> 00:04:11.503 for treating all dysfunctions. 00:04:11.503 --> 00:04:15.670 So example free association, therapist's interpretation, 00:04:17.515 --> 00:04:20.954 transference, resistance, dream analysis. 00:04:20.954 --> 00:04:23.300 So those items that we had mentioned earlier 00:04:23.300 --> 00:04:24.450 when we were taking a look 00:04:24.450 --> 00:04:26.975 at some of the different approaches. 00:04:26.975 --> 00:04:30.355 Specific treatment for GAD, the Freudians focus less 00:04:30.355 --> 00:04:34.857 on the fear and more on the control of the id. 00:04:34.857 --> 00:04:38.348 Object-Relations therapists attempt to help patients 00:04:38.348 --> 00:04:42.348 identify and settle early-relationship problems. 00:04:43.354 --> 00:04:45.828 Overall though, the research has shown 00:04:45.828 --> 00:04:48.281 that the psychodynamic approaches 00:04:48.281 --> 00:04:52.448 to be of only modest help in treating cases of GAD. 00:04:54.329 --> 00:04:58.491 So now let's take a look at the humanistic perspective. 00:04:58.491 --> 00:05:01.094 According to the humanistic perspective, 00:05:01.094 --> 00:05:05.177 GAD arises when people stop looking at themselves 00:05:08.258 --> 00:05:10.887 honestly and acceptingly. 00:05:10.887 --> 00:05:13.634 And we have to look to Carl Rogers who again, 00:05:13.634 --> 00:05:17.801 we first met when we talked about the humanistic approach, 00:05:18.813 --> 00:05:20.955 but according to Carl Rogers, 00:05:20.955 --> 00:05:25.204 the lack of unconditional positive regard in childhood 00:05:25.204 --> 00:05:29.371 leads to harsh self-standards, known as conditions of worth. 00:05:30.306 --> 00:05:32.743 These threatening self-judgments break through 00:05:32.743 --> 00:05:36.910 and cause anxiety, setting the stage for GAD to develop. 00:05:38.614 --> 00:05:43.409 Carl Rogers proposed client-centered therapy then 00:05:43.409 --> 00:05:47.774 in which unconditional positive regard is given 00:05:47.774 --> 00:05:51.191 to help the individual deal with anxiety. 00:05:53.990 --> 00:05:56.985 The cognitive perspective believes 00:05:56.985 --> 00:05:59.189 that psychological problems are caused 00:05:59.189 --> 00:06:01.920 by dysfunctional ways of thinking, 00:06:01.920 --> 00:06:04.503 in particular, excessive worry. 00:06:05.635 --> 00:06:08.851 And very often, cognitive therapists will say 00:06:08.851 --> 00:06:11.237 that someone who is dealing with GAD 00:06:11.237 --> 00:06:15.404 is dealing with this because it's caused primarily 00:06:16.340 --> 00:06:19.097 by maladaptive assumptions. 00:06:19.097 --> 00:06:20.791 The person that we want associating 00:06:20.791 --> 00:06:23.222 with this approach is Albert Ellis. 00:06:23.222 --> 00:06:25.305 And he proposed that the presence 00:06:25.305 --> 00:06:28.082 of these basic irrational assumptions 00:06:28.082 --> 00:06:31.502 lead people to act in inappropriate ways 00:06:31.502 --> 00:06:36.134 when these assumptions are relied on in everyday life. 00:06:36.134 --> 00:06:38.966 Another theorist, Aaron Beck, argued 00:06:38.966 --> 00:06:42.365 that those with Generalized Anxiety Disorder hold 00:06:42.365 --> 00:06:46.532 unrealistic silent assumptions implying imminent danger. 00:06:48.412 --> 00:06:51.653 And research does suggest or support the notion 00:06:51.653 --> 00:06:55.820 that people with GAD do hold these maladaptive assumptions, 00:06:58.003 --> 00:07:00.423 especially when they're facing situations 00:07:00.423 --> 00:07:03.090 that are particularly dangerous. 00:07:05.104 --> 00:07:08.714 Biological perspective then, believes 00:07:08.714 --> 00:07:13.054 that GAD is caused primarily by biological factors. 00:07:13.054 --> 00:07:15.331 And in particular, what we're gonna focus on 00:07:15.331 --> 00:07:17.450 are the pedigree studies. 00:07:17.450 --> 00:07:21.204 And in fact, the pedigree studies find 00:07:21.204 --> 00:07:24.817 significant support for the biological approach. 00:07:24.817 --> 00:07:29.208 Biological relatives are more likely to develop GAD, 00:07:29.208 --> 00:07:33.763 about 15%, compared to the general population, 00:07:33.763 --> 00:07:36.808 which is only approximately 6%. 00:07:36.808 --> 00:07:40.163 And what we find is that the closer relative, 00:07:40.163 --> 00:07:42.423 the greater the likelihood. 00:07:42.423 --> 00:07:46.685 However, there is also some evidence or some indication 00:07:46.685 --> 00:07:50.852 that shared-upbringing can contribute to having GAD. 00:07:56.717 --> 00:08:00.884 Alright, when we take a look at the neurotransmitter GABA, 00:08:01.739 --> 00:08:06.616 we find that GABA inactivity does contribute to it, 00:08:06.616 --> 00:08:10.783 and may play a role in an individual developing GAD. 00:08:13.435 --> 00:08:17.125 So when we take a look at the biology of anxiety, 00:08:17.125 --> 00:08:18.953 we find that the circuit in the brain 00:08:18.953 --> 00:08:21.976 that helps produce anxiety reactions, 00:08:21.976 --> 00:08:25.285 includes areas such as the amygdala, 00:08:25.285 --> 00:08:30.265 the prefrontal cortex, and the anterior cingulate cortex. 00:08:30.265 --> 00:08:32.397 So in other words, what we are finding 00:08:32.397 --> 00:08:35.837 is that there are definitely certain parts of the brain 00:08:35.837 --> 00:08:38.587 that are impacting one's anxiety. 00:08:41.673 --> 00:08:45.152 So when we take a look at treatment, 00:08:45.152 --> 00:08:47.903 the anti-anxiety medications, 00:08:47.903 --> 00:08:52.070 the pre-1950s treatments were primarily barbiturates. 00:08:53.465 --> 00:08:57.253 Post-1950 treatments were Benzodiazepines, 00:08:57.253 --> 00:09:00.461 and they provide temporary modest relief, 00:09:00.461 --> 00:09:04.139 but they can cause rebound-anxiety with withdrawal 00:09:04.139 --> 00:09:07.638 when you stop using them, and physical dependence, 00:09:07.638 --> 00:09:10.662 we know, is definitely very possible. 00:09:10.662 --> 00:09:13.286 In addition, Benzodiazepines 00:09:13.286 --> 00:09:17.453 also have undesirable effects, such as drowsiness. 00:09:20.394 --> 00:09:23.989 More recently, other medications have become available, 00:09:23.989 --> 00:09:28.156 such as antidepressants and antipsychotic medications. 00:09:29.150 --> 00:09:32.457 In addition, there is relaxation training, 00:09:32.457 --> 00:09:36.910 in which someone learns to physically relax, 00:09:36.910 --> 00:09:40.574 which will lead to psychological relaxation, 00:09:40.574 --> 00:09:45.128 and in particular, on the use of biofeedback. 00:09:45.128 --> 00:09:46.711 So with biofeedback, 00:09:46.711 --> 00:09:50.903 there're electrical signals from the body 00:09:50.903 --> 00:09:52.327 that are used to train people 00:09:52.327 --> 00:09:55.740 to control their physiological responses. 00:09:55.740 --> 00:09:58.666 The most widely used biofeedback tool 00:09:58.666 --> 00:10:01.828 is this electromyograph or EMG, 00:10:01.828 --> 00:10:05.430 which provides feedback about muscle tension. 00:10:05.430 --> 00:10:09.097 The greatest impact is found when it is used 00:10:10.571 --> 00:10:14.321 in combination with other medical treatments. 00:10:16.183 --> 00:10:18.178 Alright, this mini lecture took a look 00:10:18.178 --> 00:10:21.459 at Generalized Anxiety, the symptoms, 00:10:21.459 --> 00:10:22.970 and the different theories, 00:10:22.970 --> 00:10:26.137 as to what causes Generalized Anxiety.