1 00:00:00,220 --> 00:00:01,803 - [Instructor] Now let's take a look 2 00:00:01,803 --> 00:00:05,053 at Generalized Anxiety Disorder or GAD. 3 00:00:06,017 --> 00:00:08,164 And this disorder is characterized 4 00:00:08,164 --> 00:00:12,440 by excessive anxiety under most circumstances 5 00:00:12,440 --> 00:00:15,523 and worry about practically anything. 6 00:00:16,448 --> 00:00:19,444 GADs sometimes is what is also referred to 7 00:00:19,444 --> 00:00:21,527 as free-floating anxiety. 8 00:00:24,325 --> 00:00:28,320 It usually first appears in childhood or adolescence 9 00:00:28,320 --> 00:00:32,946 and in fact it is quite common in the Western society. 10 00:00:32,946 --> 00:00:35,740 Women tend to be diagnosed more than men 11 00:00:35,740 --> 00:00:38,414 by about a ratio of two to one. 12 00:00:38,414 --> 00:00:42,581 And about 1/4 of people who are diagnosed with this 13 00:00:43,539 --> 00:00:46,380 are currently in treatment. 14 00:00:46,380 --> 00:00:47,797 And there you see 15 00:00:48,842 --> 00:00:52,425 the characteristics for GAD from the DSM-5. 16 00:00:53,682 --> 00:00:56,142 For six months and more, the person experiences 17 00:00:56,142 --> 00:00:59,183 disproportionate, uncontrollable, 18 00:00:59,183 --> 00:01:03,945 and ongoing anxiety and worry about multiple matters. 19 00:01:03,945 --> 00:01:07,230 The symptoms include at least three of the following. 20 00:01:07,230 --> 00:01:11,397 Edginess, fatigue, poor concentration, irritability, 21 00:01:12,460 --> 00:01:15,235 muscle tension, and sleep problems. 22 00:01:15,235 --> 00:01:18,236 And there's significant distress or impairment 23 00:01:18,236 --> 00:01:20,175 with the disorder. 24 00:01:20,175 --> 00:01:21,675 And we know that there are a variety 25 00:01:21,675 --> 00:01:25,842 of theoretical explanations to explain Generalized Anxiety, 26 00:01:27,288 --> 00:01:31,183 so let's take a look at those theoretical explanations. 27 00:01:31,183 --> 00:01:34,968 The first is the socio-cultural perspective, 28 00:01:34,968 --> 00:01:36,075 which basically focuses 29 00:01:36,075 --> 00:01:39,242 on societal and multicultural factors. 30 00:01:41,242 --> 00:01:45,049 For this perspective, GAD is most likely to develop 31 00:01:45,049 --> 00:01:47,987 in people faced with social conditions 32 00:01:47,987 --> 00:01:50,070 that are truly dangerous. 33 00:01:51,221 --> 00:01:54,054 Research supports this theory. 34 00:01:54,054 --> 00:01:57,102 For example, when you take a look at situations like 35 00:01:57,102 --> 00:02:01,667 nuclear disaster, the Three Mile Island in 1979, 36 00:02:01,667 --> 00:02:05,834 Hurricane Katrina in 2005, the Haiti Earthquake in 2010, 37 00:02:08,425 --> 00:02:13,040 we've found significantly higher rates of GAD. 38 00:02:13,040 --> 00:02:16,645 A lot of the most powerful forms of societal stress 39 00:02:16,645 --> 00:02:20,514 is poverty, and we find that those individuals 40 00:02:20,514 --> 00:02:25,147 who face less equality, less power, greater vulnerability, 41 00:02:25,147 --> 00:02:28,558 rundown communities, higher crime rates, 42 00:02:28,558 --> 00:02:31,669 fewer educational and job opportunities, 43 00:02:31,669 --> 00:02:35,836 are definitely at a greater risk for health problems. 44 00:02:36,812 --> 00:02:39,666 And as would be predicted by this model then, 45 00:02:39,666 --> 00:02:42,273 rates of GAD are generally higher 46 00:02:42,273 --> 00:02:45,741 in lower socio-academic status groups. 47 00:02:45,741 --> 00:02:48,801 However, while the poverty and other social pressures 48 00:02:48,801 --> 00:02:51,371 may create a climate for GAD, 49 00:02:51,371 --> 00:02:54,831 other factors are clearly at work. 50 00:02:54,831 --> 00:02:56,288 And we find that quite honestly, 51 00:02:56,288 --> 00:02:59,182 most people who're living in dangerous environments 52 00:02:59,182 --> 00:03:01,958 don't actually develop GAD, 53 00:03:01,958 --> 00:03:04,306 and other models will attempt to explain then 54 00:03:04,306 --> 00:03:08,473 why some people develop the disorder and others do not, 55 00:03:09,922 --> 00:03:14,089 such as this perspective, the psychodynamic perspective. 56 00:03:15,036 --> 00:03:16,896 The psychodynamic perspective believe 57 00:03:16,896 --> 00:03:19,902 that all children experience anxiety 58 00:03:19,902 --> 00:03:24,094 and use defense mechanisms to help control it. 59 00:03:24,094 --> 00:03:28,615 Realistic anxiety results from actual danger. 60 00:03:28,615 --> 00:03:31,286 Neurotic anxiety, though, results when children 61 00:03:31,286 --> 00:03:35,286 are prevented from expressing their id impulses. 62 00:03:36,916 --> 00:03:40,471 So Freud believes then, that excessive childhood neurotic 63 00:03:40,471 --> 00:03:43,721 or moral anxiety set the stage for GAD. 64 00:03:44,955 --> 00:03:48,142 Contemporary theorists, however, often disagree 65 00:03:48,142 --> 00:03:51,768 with very specific aspects of Freud's explanation, 66 00:03:51,768 --> 00:03:54,338 though most continue to believe that the disorder 67 00:03:54,338 --> 00:03:58,505 can be traced to an adequate parent-child relationships. 68 00:04:00,675 --> 00:04:03,184 So when we take a look at the techniques 69 00:04:03,184 --> 00:04:06,307 that are used or the therapies, 70 00:04:06,307 --> 00:04:09,024 in general they use the same general techniques 71 00:04:09,024 --> 00:04:11,503 for treating all dysfunctions. 72 00:04:11,503 --> 00:04:15,670 So example free association, therapist's interpretation, 73 00:04:17,515 --> 00:04:20,954 transference, resistance, dream analysis. 74 00:04:20,954 --> 00:04:23,300 So those items that we had mentioned earlier 75 00:04:23,300 --> 00:04:24,450 when we were taking a look 76 00:04:24,450 --> 00:04:26,975 at some of the different approaches. 77 00:04:26,975 --> 00:04:30,355 Specific treatment for GAD, the Freudians focus less 78 00:04:30,355 --> 00:04:34,857 on the fear and more on the control of the id. 79 00:04:34,857 --> 00:04:38,348 Object-Relations therapists attempt to help patients 80 00:04:38,348 --> 00:04:42,348 identify and settle early-relationship problems. 81 00:04:43,354 --> 00:04:45,828 Overall though, the research has shown 82 00:04:45,828 --> 00:04:48,281 that the psychodynamic approaches 83 00:04:48,281 --> 00:04:52,448 to be of only modest help in treating cases of GAD. 84 00:04:54,329 --> 00:04:58,491 So now let's take a look at the humanistic perspective. 85 00:04:58,491 --> 00:05:01,094 According to the humanistic perspective, 86 00:05:01,094 --> 00:05:05,177 GAD arises when people stop looking at themselves 87 00:05:08,258 --> 00:05:10,887 honestly and acceptingly. 88 00:05:10,887 --> 00:05:13,634 And we have to look to Carl Rogers who again, 89 00:05:13,634 --> 00:05:17,801 we first met when we talked about the humanistic approach, 90 00:05:18,813 --> 00:05:20,955 but according to Carl Rogers, 91 00:05:20,955 --> 00:05:25,204 the lack of unconditional positive regard in childhood 92 00:05:25,204 --> 00:05:29,371 leads to harsh self-standards, known as conditions of worth. 93 00:05:30,306 --> 00:05:32,743 These threatening self-judgments break through 94 00:05:32,743 --> 00:05:36,910 and cause anxiety, setting the stage for GAD to develop. 95 00:05:38,614 --> 00:05:43,409 Carl Rogers proposed client-centered therapy then 96 00:05:43,409 --> 00:05:47,774 in which unconditional positive regard is given 97 00:05:47,774 --> 00:05:51,191 to help the individual deal with anxiety. 98 00:05:53,990 --> 00:05:56,985 The cognitive perspective believes 99 00:05:56,985 --> 00:05:59,189 that psychological problems are caused 100 00:05:59,189 --> 00:06:01,920 by dysfunctional ways of thinking, 101 00:06:01,920 --> 00:06:04,503 in particular, excessive worry. 102 00:06:05,635 --> 00:06:08,851 And very often, cognitive therapists will say 103 00:06:08,851 --> 00:06:11,237 that someone who is dealing with GAD 104 00:06:11,237 --> 00:06:15,404 is dealing with this because it's caused primarily 105 00:06:16,340 --> 00:06:19,097 by maladaptive assumptions. 106 00:06:19,097 --> 00:06:20,791 The person that we want associating 107 00:06:20,791 --> 00:06:23,222 with this approach is Albert Ellis. 108 00:06:23,222 --> 00:06:25,305 And he proposed that the presence 109 00:06:25,305 --> 00:06:28,082 of these basic irrational assumptions 110 00:06:28,082 --> 00:06:31,502 lead people to act in inappropriate ways 111 00:06:31,502 --> 00:06:36,134 when these assumptions are relied on in everyday life. 112 00:06:36,134 --> 00:06:38,966 Another theorist, Aaron Beck, argued 113 00:06:38,966 --> 00:06:42,365 that those with Generalized Anxiety Disorder hold 114 00:06:42,365 --> 00:06:46,532 unrealistic silent assumptions implying imminent danger. 115 00:06:48,412 --> 00:06:51,653 And research does suggest or support the notion 116 00:06:51,653 --> 00:06:55,820 that people with GAD do hold these maladaptive assumptions, 117 00:06:58,003 --> 00:07:00,423 especially when they're facing situations 118 00:07:00,423 --> 00:07:03,090 that are particularly dangerous. 119 00:07:05,104 --> 00:07:08,714 Biological perspective then, believes 120 00:07:08,714 --> 00:07:13,054 that GAD is caused primarily by biological factors. 121 00:07:13,054 --> 00:07:15,331 And in particular, what we're gonna focus on 122 00:07:15,331 --> 00:07:17,450 are the pedigree studies. 123 00:07:17,450 --> 00:07:21,204 And in fact, the pedigree studies find 124 00:07:21,204 --> 00:07:24,817 significant support for the biological approach. 125 00:07:24,817 --> 00:07:29,208 Biological relatives are more likely to develop GAD, 126 00:07:29,208 --> 00:07:33,763 about 15%, compared to the general population, 127 00:07:33,763 --> 00:07:36,808 which is only approximately 6%. 128 00:07:36,808 --> 00:07:40,163 And what we find is that the closer relative, 129 00:07:40,163 --> 00:07:42,423 the greater the likelihood. 130 00:07:42,423 --> 00:07:46,685 However, there is also some evidence or some indication 131 00:07:46,685 --> 00:07:50,852 that shared-upbringing can contribute to having GAD. 132 00:07:56,717 --> 00:08:00,884 Alright, when we take a look at the neurotransmitter GABA, 133 00:08:01,739 --> 00:08:06,616 we find that GABA inactivity does contribute to it, 134 00:08:06,616 --> 00:08:10,783 and may play a role in an individual developing GAD. 135 00:08:13,435 --> 00:08:17,125 So when we take a look at the biology of anxiety, 136 00:08:17,125 --> 00:08:18,953 we find that the circuit in the brain 137 00:08:18,953 --> 00:08:21,976 that helps produce anxiety reactions, 138 00:08:21,976 --> 00:08:25,285 includes areas such as the amygdala, 139 00:08:25,285 --> 00:08:30,265 the prefrontal cortex, and the anterior cingulate cortex. 140 00:08:30,265 --> 00:08:32,397 So in other words, what we are finding 141 00:08:32,397 --> 00:08:35,837 is that there are definitely certain parts of the brain 142 00:08:35,837 --> 00:08:38,587 that are impacting one's anxiety. 143 00:08:41,673 --> 00:08:45,152 So when we take a look at treatment, 144 00:08:45,152 --> 00:08:47,903 the anti-anxiety medications, 145 00:08:47,903 --> 00:08:52,070 the pre-1950s treatments were primarily barbiturates. 146 00:08:53,465 --> 00:08:57,253 Post-1950 treatments were Benzodiazepines, 147 00:08:57,253 --> 00:09:00,461 and they provide temporary modest relief, 148 00:09:00,461 --> 00:09:04,139 but they can cause rebound-anxiety with withdrawal 149 00:09:04,139 --> 00:09:07,638 when you stop using them, and physical dependence, 150 00:09:07,638 --> 00:09:10,662 we know, is definitely very possible. 151 00:09:10,662 --> 00:09:13,286 In addition, Benzodiazepines 152 00:09:13,286 --> 00:09:17,453 also have undesirable effects, such as drowsiness. 153 00:09:20,394 --> 00:09:23,989 More recently, other medications have become available, 154 00:09:23,989 --> 00:09:28,156 such as antidepressants and antipsychotic medications. 155 00:09:29,150 --> 00:09:32,457 In addition, there is relaxation training, 156 00:09:32,457 --> 00:09:36,910 in which someone learns to physically relax, 157 00:09:36,910 --> 00:09:40,574 which will lead to psychological relaxation, 158 00:09:40,574 --> 00:09:45,128 and in particular, on the use of biofeedback. 159 00:09:45,128 --> 00:09:46,711 So with biofeedback, 160 00:09:46,711 --> 00:09:50,903 there're electrical signals from the body 161 00:09:50,903 --> 00:09:52,327 that are used to train people 162 00:09:52,327 --> 00:09:55,740 to control their physiological responses. 163 00:09:55,740 --> 00:09:58,666 The most widely used biofeedback tool 164 00:09:58,666 --> 00:10:01,828 is this electromyograph or EMG, 165 00:10:01,828 --> 00:10:05,430 which provides feedback about muscle tension. 166 00:10:05,430 --> 00:10:09,097 The greatest impact is found when it is used 167 00:10:10,571 --> 00:10:14,321 in combination with other medical treatments. 168 00:10:16,183 --> 00:10:18,178 Alright, this mini lecture took a look 169 00:10:18,178 --> 00:10:21,459 at Generalized Anxiety, the symptoms, 170 00:10:21,459 --> 00:10:22,970 and the different theories, 171 00:10:22,970 --> 00:10:26,137 as to what causes Generalized Anxiety.