1 99:59:59,999 --> 99:59:59,999 Thank you very much. 2 99:59:59,999 --> 99:59:59,999 Well, I would like to start with testicles. 3 99:59:59,999 --> 99:59:59,999 (Laughter) 4 99:59:59,999 --> 99:59:59,999 Men who sleep five hours a night 5 99:59:59,999 --> 99:59:59,999 have significantly smaller testicles than those who sleep seven hours or more. 6 99:59:59,999 --> 99:59:59,999 (Laughter) 7 99:59:59,999 --> 99:59:59,999 In addition, men who routinely sleep just four to five hours a night 8 99:59:59,999 --> 99:59:59,999 will have a level of testosterone 9 99:59:59,999 --> 99:59:59,999 which is that of someone 10 years their senior. 10 99:59:59,999 --> 99:59:59,999 So a lack of sleep will age a man by a decade 11 99:59:59,999 --> 99:59:59,999 in terms of that critical aspect of wellness. 12 99:59:59,999 --> 99:59:59,999 And we see equivalent impairments in female reproductive health 13 99:59:59,999 --> 99:59:59,999 caused by a lack of sleep. 14 99:59:59,999 --> 99:59:59,999 This is the best news that I have for you today. 15 99:59:59,999 --> 99:59:59,999 (Laughter) 16 99:59:59,999 --> 99:59:59,999 From this point, it may only get worse. 17 99:59:59,999 --> 99:59:59,999 Not only will I tell you about the wonderfully good things 18 99:59:59,999 --> 99:59:59,999 that happen when you get sleep 19 99:59:59,999 --> 99:59:59,999 but the alarmingly bad things that happen when you don't get enough, 20 99:59:59,999 --> 99:59:59,999 both for your brain and for your body. 21 99:59:59,999 --> 99:59:59,999 Let me start with the brain 22 99:59:59,999 --> 99:59:59,999 and the functions of learning and memory, 23 99:59:59,999 --> 99:59:59,999 because what we've discovered over the past 10 or so years 24 99:59:59,999 --> 99:59:59,999 is that you need sleep after learning 25 99:59:59,999 --> 99:59:59,999 to essentially hit the save button on those new memories 26 99:59:59,999 --> 99:59:59,999 so that you don't forget. 27 99:59:59,999 --> 99:59:59,999 But recently we discovered 28 99:59:59,999 --> 99:59:59,999 that you also need sleep before learning, 29 99:59:59,999 --> 99:59:59,999 and now to actually prepare your brain, 30 99:59:59,999 --> 99:59:59,999 almost like a dry sponge 31 99:59:59,999 --> 99:59:59,999 ready to initially soak up new information. 32 99:59:59,999 --> 99:59:59,999 And without sleep, the memory circuits of the brain 33 99:59:59,999 --> 99:59:59,999 essentially become waterlogged, 34 99:59:59,999 --> 99:59:59,999 as it were, 35 99:59:59,999 --> 99:59:59,999 and you can't absorb new memories. 36 99:59:59,999 --> 99:59:59,999 So let me show you the data. 37 99:59:59,999 --> 99:59:59,999 Here in this study, we decided to test the hypothesis 38 99:59:59,999 --> 99:59:59,999 that pulling the all-nighter was a good idea. 39 99:59:59,999 --> 99:59:59,999 So we took a group of individuals 40 99:59:59,999 --> 99:59:59,999 and we assigned them to one of two experimental groups: 41 99:59:59,999 --> 99:59:59,999 a sleep group, 42 99:59:59,999 --> 99:59:59,999 and a sleep deprivation group.