1 99:59:59,999 --> 99:59:59,999 We have historical records that allow us to know how the ancient Greeks dressed, 2 99:59:59,999 --> 99:59:59,999 how they lived, 3 99:59:59,999 --> 99:59:59,999 how they fought. 4 99:59:59,999 --> 99:59:59,999 But how did they think? 5 99:59:59,999 --> 99:59:59,999 One natural idea is that the deepest aspects of human thought, 6 99:59:59,999 --> 99:59:59,999 out ability to imagine, 7 99:59:59,999 --> 99:59:59,999 to be concious, 8 99:59:59,999 --> 99:59:59,999 to dream, 9 99:59:59,999 --> 99:59:59,999 have always been the same. 10 99:59:59,999 --> 99:59:59,999 Another possibility 11 99:59:59,999 --> 99:59:59,999 is that the social transformations that have shaped our culture 12 99:59:59,999 --> 99:59:59,999 make us also change the structural columns of human thought. 13 99:59:59,999 --> 99:59:59,999 We may all have different opinions about this. 14 99:59:59,999 --> 99:59:59,999 Actually, it's a longstanding philosophical debate. 15 99:59:59,999 --> 99:59:59,999 But is this question even amenable to science? 16 99:59:59,999 --> 99:59:59,999 Here I'd like to propose that in the same way 17 99:59:59,999 --> 99:59:59,999 that in the same way that we can reconstruct 18 99:59:59,999 --> 99:59:59,999 how the ancient Greek cities looked like, 19 99:59:59,999 --> 99:59:59,999 just based on a few bricks, 20 99:59:59,999 --> 99:59:59,999 that the writings of a culture are the archealogical records -- 21 99:59:59,999 --> 99:59:59,999 the fossils -- 22 99:59:59,999 --> 99:59:59,999 of human thought. 23 99:59:59,999 --> 99:59:59,999 And in fact, 24 99:59:59,999 --> 99:59:59,999 doing some form of psychological analysis 25 99:59:59,999 --> 99:59:59,999 of some of the most ancient books of human culture, 26 99:59:59,999 --> 99:59:59,999 Julian James came in the '70s with a very wild and radical hypothesis, 27 99:59:59,999 --> 99:59:59,999 that only 3,000 years ago, 28 99:59:59,999 --> 99:59:59,999 humans were today what we'd call, schizophrenics. 29 99:59:59,999 --> 99:59:59,999 And he made this claim 30 99:59:59,999 --> 99:59:59,999 based on the fact that the first humans writing these books behaved consistently 31 99:59:59,999 --> 99:59:59,999 in different traditions and in different places of the world, 32 99:59:59,999 --> 99:59:59,999 as if they were hearing and obeying voices 33 99:59:59,999 --> 99:59:59,999 that they perceived as coming from the Gods, 34 99:59:59,999 --> 99:59:59,999 or from the muses. 35 99:59:59,999 --> 99:59:59,999 What today we'd call hallucinations. 36 99:59:59,999 --> 99:59:59,999 And only then, 37 99:59:59,999 --> 99:59:59,999 as time went on, 38 99:59:59,999 --> 99:59:59,999 they began to recognize that they were the creators -- 39 99:59:59,999 --> 99:59:59,999 the owners of these inner voices. 40 99:59:59,999 --> 99:59:59,999 And with this they gained introspection: 41 99:59:59,999 --> 99:59:59,999 the ability to think about their own thoughts. 42 99:59:59,999 --> 99:59:59,999 So Jaynes' theory is that conciousness, 43 99:59:59,999 --> 99:59:59,999 at least in the way we perceive it today, 44 99:59:59,999 --> 99:59:59,999 where we feel that we are the pilots of our own existence, 45 99:59:59,999 --> 99:59:59,999 is a quite recent cultural development. 46 99:59:59,999 --> 99:59:59,999 And this theory is quite spectacular, 47 99:59:59,999 --> 99:59:59,999 because an obvious problem, 48 99:59:59,999 --> 99:59:59,999 which is that it's built on just a few and very specific examples. 49 99:59:59,999 --> 99:59:59,999 So the question is 50 99:59:59,999 --> 99:59:59,999 whether the theory that introspection built up only about 3,000 years ago, 51 99:59:59,999 --> 99:59:59,999 can be examined in a quantitative and objective way. 52 99:59:59,999 --> 99:59:59,999 And the problem on how to go about this is quite obvious. 53 99:59:59,999 --> 99:59:59,999 It's not like Plato woke up one day 54 99:59:59,999 --> 99:59:59,999 and then he wrote, 55 99:59:59,999 --> 99:59:59,999 "Hello, I'm Plato 56 99:59:59,999 --> 99:59:59,999 and as of today I have a fully introspective consciousness." 57 99:59:59,999 --> 99:59:59,999 (Laughter) 58 99:59:59,999 --> 99:59:59,999 And this still is actually what is the essence of the problem. 59 99:59:59,999 --> 99:59:59,999 We need to find the emergence of a concept that's never said. 60 99:59:59,999 --> 99:59:59,999 The word introspection does not appear a single time 61 99:59:59,999 --> 99:59:59,999 in the books we want to analyze. 62 99:59:59,999 --> 99:59:59,999 So our way to solve this is to build the space of words. 63 99:59:59,999 --> 99:59:59,999 This is a huge space that contains all words 64 99:59:59,999 --> 99:59:59,999 in such a way that they distance between any two of them 65 99:59:59,999 --> 99:59:59,999 is indicative of how closely related they are. 66 99:59:59,999 --> 99:59:59,999 So for instance, 67 99:59:59,999 --> 99:59:59,999 you want the words dog and cat to be very close together, 68 99:59:59,999 --> 99:59:59,999 but the words grapefruit and logarithm to be very far away. 69 99:59:59,999 --> 99:59:59,999 And this has to be true for any two words within the space. 70 99:59:59,999 --> 99:59:59,999 And there are different ways that we can construct the space of words. 71 99:59:59,999 --> 99:59:59,999 One is just asking the experts, 72 99:59:59,999 --> 99:59:59,999 a bit like we do with dictionaries. 73 99:59:59,999 --> 99:59:59,999 Another possibility 74 99:59:59,999 --> 99:59:59,999 is following the simple assumption 75 99:59:59,999 --> 99:59:59,999 that when two words are related they tend to appear in the same sentences, 76 99:59:59,999 --> 99:59:59,999 in the same paragraphs, 77 99:59:59,999 --> 99:59:59,999 in the same documents, 78 99:59:59,999 --> 99:59:59,999 more often than would be expected just by pure chance. 79 99:59:59,999 --> 99:59:59,999 And this simple hypothesis, 80 99:59:59,999 --> 99:59:59,999 this simple method, 81 99:59:59,999 --> 99:59:59,999 with some computational tricks 82 99:59:59,999 --> 99:59:59,999 that have to do with the fact 83 99:59:59,999 --> 99:59:59,999 that this is a very complex and highly dimensional space, 84 99:59:59,999 --> 99:59:59,999 turns out to be quite effective. 85 99:59:59,999 --> 99:59:59,999 And just to give you a flavor of how well this works, 86 99:59:59,999 --> 99:59:59,999 this is the result we get when we analyze this for some familiar words. 87 99:59:59,999 --> 99:59:59,999 And you can see first 88 99:59:59,999 --> 99:59:59,999 that words automatically organize into semantic neighborhoods. 89 99:59:59,999 --> 99:59:59,999 So you get the fruits, 90 99:59:59,999 --> 99:59:59,999 the body parts, 91 99:59:59,999 --> 99:59:59,999 the computer parts, 92 99:59:59,999 --> 99:59:59,999 the scientific terms 93 99:59:59,999 --> 99:59:59,999 and so on. 94 99:59:59,999 --> 99:59:59,999 The algorithm also identifies the reorganized concepts in a hierarchy. 95 99:59:59,999 --> 99:59:59,999 So for instance, 96 99:59:59,999 --> 99:59:59,999 you can see that the scientific terms break down into two subcategories 97 99:59:59,999 --> 99:59:59,999 of the astronomic and the physic terms. 98 99:59:59,999 --> 99:59:59,999 And then their are very fine things. 99 99:59:59,999 --> 99:59:59,999 For instance, 100 99:59:59,999 --> 99:59:59,999 the word astronomy, 101 99:59:59,999 --> 99:59:59,999 which seems a bit bizarre where it is, 102 99:59:59,999 --> 99:59:59,999 is actually exactly where it should be, 103 99:59:59,999 --> 99:59:59,999 between what it is -- 104 99:59:59,999 --> 99:59:59,999 an actual science -- 105 99:59:59,999 --> 99:59:59,999 and between what it describes -- 106 99:59:59,999 --> 99:59:59,999 the astronomical terms. 107 99:59:59,999 --> 99:59:59,999 And we could go on and on with this. 108 99:59:59,999 --> 99:59:59,999 Actually if you stare at this for awhile 109 99:59:59,999 --> 99:59:59,999 and you just build random trajectories, 110 99:59:59,999 --> 99:59:59,999 you will see that is feels well -- 111 99:59:59,999 --> 99:59:59,999 actually it feels a bit like doing poetry. 112 99:59:59,999 --> 99:59:59,999 And this is because in way, 113 99:59:59,999 --> 99:59:59,999 walking in this space is like walking in the mind. 114 99:59:59,999 --> 99:59:59,999 And last thing is that this algorithm also identifies what are our intuitions, 115 99:59:59,999 --> 99:59:59,999 of which words should lead in the neighborhood of introspection. 116 99:59:59,999 --> 99:59:59,999 So for instance, 117 99:59:59,999 --> 99:59:59,999 words such as Self, Guilt, Reason, Emotion, 118 99:59:59,999 --> 99:59:59,999 are very close to introspection, 119 99:59:59,999 --> 99:59:59,999 but other words, 120 99:59:59,999 --> 99:59:59,999 such as Red, Football, Candle, Banana, 121 99:59:59,999 --> 99:59:59,999 are just very far away. 122 99:59:59,999 --> 99:59:59,999 And so once we've built this space, 123 99:59:59,999 --> 99:59:59,999 the question of the history of introspection, 124 99:59:59,999 --> 99:59:59,999 or of the history of any concept, 125 99:59:59,999 --> 99:59:59,999 which before could seem abstract and somehow vague, 126 99:59:59,999 --> 99:59:59,999 becomes concrete -- 127 99:59:59,999 --> 99:59:59,999 becomes amenable to quantitative science. 128 99:59:59,999 --> 99:59:59,999 All that we have to do is take the books, 129 99:59:59,999 --> 99:59:59,999 we digitize them 130 99:59:59,999 --> 99:59:59,999 and we take this stream of words as a trajectory 131 99:59:59,999 --> 99:59:59,999 and project them into this space, 132 99:59:59,999 --> 99:59:59,999 and then we ask whether this trajectory spends significant time 133 99:59:59,999 --> 99:59:59,999 circling closely to the concept of introspection. 134 99:59:59,999 --> 99:59:59,999 And with this, 135 99:59:59,999 --> 99:59:59,999 we can analyze the history of introspection 136 99:59:59,999 --> 99:59:59,999 in the ancient Greek tradition, 137 99:59:59,999 --> 99:59:59,999 for which we have the best available written record. 138 99:59:59,999 --> 99:59:59,999 So what we did is we took all the books -- 139 99:59:59,999 --> 99:59:59,999 we just ordered them by time -- 140 99:59:59,999 --> 99:59:59,999 for each book we take the words 141 99:59:59,999 --> 99:59:59,999 and we project them to the space, 142 99:59:59,999 --> 99:59:59,999 and then we ask for each word how close it is to introspection, 143 99:59:59,999 --> 99:59:59,999 and we just average that. 144 99:59:59,999 --> 99:59:59,999 And then we understand that as time goes on and on, 145 99:59:59,999 --> 99:59:59,999 these books get closer, and closer and closer 146 99:59:59,999 --> 99:59:59,999 to the concept of introspection. 147 99:59:59,999 --> 99:59:59,999 And this is exactly what happens in the ancient Greek tradition. 148 99:59:59,999 --> 99:59:59,999 So you can see that for the oldest books in the Homeric tradition, 149 99:59:59,999 --> 99:59:59,999 there is a small increase with books getting closer to introspection, 150 99:59:59,999 --> 99:59:59,999 but about four centuries before Christ, 151 99:59:59,999 --> 99:59:59,999 this starts ramping up very rapidly 152 99:59:59,999 --> 99:59:59,999 to an almost five-fold increase 153 99:59:59,999 --> 99:59:59,999 of books getting closer, and closer and closer 154 99:59:59,999 --> 99:59:59,999 to the concept of introspection. 155 99:59:59,999 --> 99:59:59,999 And one of the nice things about this 156 99:59:59,999 --> 99:59:59,999 is that now we can ask 157 99:59:59,999 --> 99:59:59,999 whether this is also true in a different independent tradition. 158 99:59:59,999 --> 99:59:59,999 So we just ran this same analysis on the Judeo Christian tradition, 159 99:59:59,999 --> 99:59:59,999 and we got virtually the same pattern. 160 99:59:59,999 --> 99:59:59,999 Again you see a small increase for the oldest books in the old testament, 161 99:59:59,999 --> 99:59:59,999 and then it increases much more rapidly 162 99:59:59,999 --> 99:59:59,999 in the new books of the new testament, 163 99:59:59,999 --> 99:59:59,999 and then we get the peak of introspection 164 99:59:59,999 --> 99:59:59,999 in the work Confessions of Saint Augustine, 165 99:59:59,999 --> 99:59:59,999 about four centuries after Christ. 166 99:59:59,999 --> 99:59:59,999 And this was very important, 167 99:59:59,999 --> 99:59:59,999 because Saint Augustine had been recognized 168 99:59:59,999 --> 99:59:59,999 by scholars, philologists, historians, 169 99:59:59,999 --> 99:59:59,999 as one of the founders of introspection. 170 99:59:59,999 --> 99:59:59,999 Actually, some believe him to be the father of modern psychology. 171 99:59:59,999 --> 99:59:59,999 So our algorithm -- 172 99:59:59,999 --> 99:59:59,999 which has the virtue of being quantitative, 173 99:59:59,999 --> 99:59:59,999 of being objective, 174 99:59:59,999 --> 99:59:59,999 and of course of being extremely fast, 175 99:59:59,999 --> 99:59:59,999 it just runs in a fraction of a second -- 176 99:59:59,999 --> 99:59:59,999 can capture some of the most important conclusions 177 99:59:59,999 --> 99:59:59,999 of this long tradition of investigation. 178 99:59:59,999 --> 99:59:59,999 And this is in a way, one of the beauties of science, 179 99:59:59,999 --> 99:59:59,999 which is that now this idea can translated 180 99:59:59,999 --> 99:59:59,999 and generalized to a whole lot of different domains. 181 99:59:59,999 --> 99:59:59,999 So in the same way that we asked about the past of human conciousness, 182 99:59:59,999 --> 99:59:59,999 maybe the most challenging question we can pose to ourselves, 183 99:59:59,999 --> 99:59:59,999 is whether this can tell us something about the future of our unconciousness. 184 99:59:59,999 --> 99:59:59,999 To put it more precisely, 185 99:59:59,999 --> 99:59:59,999 whether the words we say today 186 99:59:59,999 --> 99:59:59,999 can tell us something of where our minds will be in a few days, 187 99:59:59,999 --> 99:59:59,999 in a few months, 188 99:59:59,999 --> 99:59:59,999 or a few years from now. 189 99:59:59,999 --> 99:59:59,999 And in the way many of us are now wearing censors 190 99:59:59,999 --> 99:59:59,999 that detect our heart rate, 191 99:59:59,999 --> 99:59:59,999 our respiration, 192 99:59:59,999 --> 99:59:59,999 our genes, 193 99:59:59,999 --> 99:59:59,999 on the hopes that this may help us prevent diseases, 194 99:59:59,999 --> 99:59:59,999 we can ask whether monitoring and analyzing the words we speak -- 195 99:59:59,999 --> 99:59:59,999 we tweet, 196 99:59:59,999 --> 99:59:59,999 we email, 197 99:59:59,999 --> 99:59:59,999 we write -- 198 99:59:59,999 --> 99:59:59,999 can tell us ahead of time whether something will go wrong with our minds. 199 99:59:59,999 --> 99:59:59,999 And with Guillermo Cecci, 200 99:59:59,999 --> 99:59:59,999 who has been my brother in this adventure, 201 99:59:59,999 --> 99:59:59,999 we took on this task. 202 99:59:59,999 --> 99:59:59,999 And we did so by analyzing the recorded speech for 44 young people 203 99:59:59,999 --> 99:59:59,999 who were at a high risk of developing schizophenia. 204 99:59:59,999 --> 99:59:59,999 And so what we did is we measured speech at day one 205 99:59:59,999 --> 99:59:59,999 and then we asked 206 99:59:59,999 --> 99:59:59,999 whether the properties of the speech could predict -- 207 99:59:59,999 --> 99:59:59,999 within a window of almost three years -- 208 99:59:59,999 --> 99:59:59,999 the future development of psychosis. 209 99:59:59,999 --> 99:59:59,999 But despite our hopes, 210 99:59:59,999 --> 99:59:59,999 we got failure after failure. 211 99:59:59,999 --> 99:59:59,999 There was just not enough information in semantics 212 99:59:59,999 --> 99:59:59,999 to predict the future organization of the mind. 213 99:59:59,999 --> 99:59:59,999 It was good enough 214 99:59:59,999 --> 99:59:59,999 to distinguish between a group of schizophrenics and a control group, 215 99:59:59,999 --> 99:59:59,999 a bit like we had done for the ancient texts, 216 99:59:59,999 --> 99:59:59,999 but not to predict the future onto the psychosis. 217 99:59:59,999 --> 99:59:59,999 But then we realized 218 99:59:59,999 --> 99:59:59,999 that maybe the most important thing was not so much what they were saying 219 99:59:59,999 --> 99:59:59,999 but how they were saying it. 220 99:59:59,999 --> 99:59:59,999 More specifically, 221 99:59:59,999 --> 99:59:59,999 it was not in which semantic neighborhoods the words were, 222 99:59:59,999 --> 99:59:59,999 but how far and fast they jumped from one semantic neighborhood to another. 223 99:59:59,999 --> 99:59:59,999 And so we came up with this measure, 224 99:59:59,999 --> 99:59:59,999 which we termed Semantic Coherence, 225 99:59:59,999 --> 99:59:59,999 which essentially measures 226 99:59:59,999 --> 99:59:59,999 the persistence of speech within one semantic topic, 227 99:59:59,999 --> 99:59:59,999 within one semantic category. 228 99:59:59,999 --> 99:59:59,999 And it turned out to be 229 99:59:59,999 --> 99:59:59,999 that for this group of 44 people, 230 99:59:59,999 --> 99:59:59,999 the algorithm based on semantic cohernece 231 99:59:59,999 --> 99:59:59,999 could predict with 100 percent accuracy 232 99:59:59,999 --> 99:59:59,999 who developed psychosis and who will not. 233 99:59:59,999 --> 99:59:59,999 And this was something that could not be achieved -- 234 99:59:59,999 --> 99:59:59,999 not even close -- 235 99:59:59,999 --> 99:59:59,999 with all the other existing clinical measures. 236 99:59:59,999 --> 99:59:59,999 And I remember vividly while I was working on this, 237 99:59:59,999 --> 99:59:59,999 I was sitting on my computer 238 99:59:59,999 --> 99:59:59,999 and I saw a bunch of tweets by Polo. 239 99:59:59,999 --> 99:59:59,999 Polo has been my first student back in Buenos Aires 240 99:59:59,999 --> 99:59:59,999 and at the time he was living in New York. 241 99:59:59,999 --> 99:59:59,999 And there was something in this tweet -- 242 99:59:59,999 --> 99:59:59,999 I could not tell exactly what because nothing was said explicitly -- 243 99:59:59,999 --> 99:59:59,999 but I got this strong hunch, 244 99:59:59,999 --> 99:59:59,999 this strong intuition that something was going wrong. 245 99:59:59,999 --> 99:59:59,999 So I picked up the phone and I called Polo, 246 99:59:59,999 --> 99:59:59,999 and he was not feeling well. 247 99:59:59,999 --> 99:59:59,999 And this simple fact that reading in between the lines 248 99:59:59,999 --> 99:59:59,999 I could sense through words his feelings, 249 99:59:59,999 --> 99:59:59,999 was a simple but very effective way to help. 250 99:59:59,999 --> 99:59:59,999 What I tell you today 251 99:59:59,999 --> 99:59:59,999 is that we're getting close to understanding 252 99:59:59,999 --> 99:59:59,999 how we can convert this intuition that we all have, 253 99:59:59,999 --> 99:59:59,999 that we all share, 254 99:59:59,999 --> 99:59:59,999 into an algorithm. 255 99:59:59,999 --> 99:59:59,999 And in doing so, 256 99:59:59,999 --> 99:59:59,999 we may be seeing in the future a very different form of mental health, 257 99:59:59,999 --> 99:59:59,999 based on objective, quantitative and automated analysis 258 99:59:59,999 --> 99:59:59,999 of the words we write, 259 99:59:59,999 --> 99:59:59,999 of the words we say. 260 99:59:59,999 --> 99:59:59,999 Gracias. 261 99:59:59,999 --> 99:59:59,999 (Applause)