1 00:00:15,750 --> 00:00:19,447 The host (from TEDxTaipei) invited me to speak about “Positive Destruction.” 2 00:00:19,447 --> 00:00:24,946 After giving it some thought, I thought I might as well share my own story. 3 00:00:24,946 --> 00:00:26,926 Among all the physicians in Taiwan, 4 00:00:26,926 --> 00:00:30,448 I am probably the one ER doctor who has seen the most cadavers. 5 00:00:30,448 --> 00:00:32,901 I've seen many cases of life and death. 6 00:00:32,901 --> 00:00:36,947 Perhaps that's why I'm suited to share such stories on this stage. 7 00:00:36,947 --> 00:00:39,314 There's a joke about 8 00:00:39,314 --> 00:00:40,871 the most famous physician -- Dr. Yeh 9 00:00:40,871 --> 00:00:42,744 here in Taiwan. 10 00:00:42,744 --> 00:00:44,530 After Shao Xiao Ling's (Taichung First Lady) car accident, 11 00:00:44,530 --> 00:00:46,613 a patient went to Chi-Mei Hospital in Liu-Ying city 12 00:00:46,613 --> 00:00:48,697 to seek a doctor named Yeh. 13 00:00:48,697 --> 00:00:49,536 The staff in the hospital said 14 00:00:49,536 --> 00:00:51,988 that there's no Dr. Yeh. 15 00:00:51,988 --> 00:00:53,206 "There is, " said the patient. 16 00:00:53,206 --> 00:00:56,421 "I was told that his name is 'Yeh Ker-Mo' (ECMO: Extra-Corporeal Membrane Oxygenation). 17 00:00:56,421 --> 00:01:00,023 This Dr. Yeh was the one who saved Shao Xiao Ling's life!" 18 00:01:00,038 --> 00:01:01,341 Speaking of ECMO, its concept is quite easy to understand. 19 00:01:01,341 --> 00:01:02,610 You divert the blood flow from the femoral vein 20 00:01:03,879 --> 00:01:05,149 and pass it through a pump, 21 00:01:05,149 --> 00:01:06,012 which serves as an artificial heart. 22 00:01:06,012 --> 00:01:07,293 The blood then passes through a membrane oxygenator, 23 00:01:07,409 --> 00:01:08,558 which acts as a pair of artificial lungs. 24 00:01:08,558 --> 00:01:10,480 Afterwards, the blood re-enters the body. 25 00:01:10,480 --> 00:01:12,939 So, ECMO is a temporary substitute of a human's cardiovascular system. 26 00:01:12,939 --> 00:01:14,973 This is how an ECMO machine looks like. 27 00:01:14,973 --> 00:01:17,486 You now have a machine acting as an artificial heart 28 00:01:17,486 --> 00:01:20,066 that pumps blood to the oxygenator and back to the body. 29 00:01:20,066 --> 00:01:22,695 As a matter of fact, ECMO technique 30 00:01:22,695 --> 00:01:24,292 was already available and widely used 31 00:01:24,292 --> 00:01:27,504 at the National Taiwan University (NTU) Hospital 32 00:01:27,504 --> 00:01:30,054 since 1994 prior to the first lady's car accident. 33 00:01:30,054 --> 00:01:31,933 It was only since her incident that folks in Taiwan are aware of the ECMO technique. 34 00:01:31,933 --> 00:01:33,384 It’s similar to the saying: "One can spend decades painting in relative obscurity," 35 00:01:33,384 --> 00:01:36,239 "but the world only sees the artist's finished masterpiece." 36 00:01:36,239 --> 00:01:37,595 That's just my personal opinion. 37 00:01:37,595 --> 00:01:41,035 ECMO became a household term due to its overexposure from Taiwan's media press. 38 00:01:41,035 --> 00:01:43,731 here's no doubt that ECMO technique has its relatively successful cases. 39 00:01:43,731 --> 00:01:45,407 One prominent example is the case of singer Jay Chou's backup dancer. 40 00:01:45,407 --> 00:01:47,830 41 00:01:47,083 --> 00:01:48,761 One day, this patient was admitted with fulminant myocarditis, 42 00:01:48,761 --> 00:01:50,947 and was undergoing cardiac arrest. 43 00:01:50,947 --> 00:01:52,999 I would like to show you a photo of him at the time, 44 00:01:52,999 --> 00:01:56,646 with the patient lying on his hospital bed. 45 00:01:56,646 --> 00:01:57,922 The eyes of this patient were wide open, 46 00:01:57,922 --> 00:01:59,414 and were staring straight, 47 00:01:59,414 --> 00:02:01,739 reading the flat lines showing on the ECG screen. 48 00:02:01,739 --> 00:02:03,317 As a result of fulminant myocarditis, 49 00:02:03,317 --> 00:02:05,474 the patient's heart stopped beating. 50 00:02:05,474 --> 00:02:07,819 He suffered a cardiac arrest. 51 00:02:07,819 --> 00:02:10,636 This is a biopsy of his cardiac muscle 52 00:02:10,636 --> 00:02:12,395 magnified 100 times under the microscope. 53 00:02:12,395 --> 00:02:13,727 Even under this type of magnifying power, 54 00:02:13,727 --> 00:02:16,312 it's still quite hard to see. 55 00:02:16,312 --> 00:02:18,831 However, magnified 400 times will be much clearer. 56 00:02:18,831 --> 00:02:22,140 Those blue spots are lymphocytes. 57 00:02:22,140 --> 00:02:26,092 From here, we can see a serious case of fulminant myocarditis. 58 00:02:26,092 --> 00:02:29,439 Lymphocytes infiltrated his entire heart, 59 00:02:29,439 --> 00:02:33,818 which caused sudden cardiac arrest. 60 00:02:33,818 --> 00:02:37,062 The patient stared at the screen, 61 00:02:37,062 --> 00:02:40,421 as it displayed no signs of a working heart. 62 00:02:40,421 --> 00:02:42,880 After the ninth day, 63 00:02:42,880 --> 00:02:44,558 after a heart and a kidney transplant, 64 00:02:44,558 --> 00:02:46,807 She returned to dance in less than one month's recovery. 65 00:02:46,807 --> 00:02:49,329 It was a great miracle in modern medicine. 66 00:02:49,329 --> 00:02:52,406 In modern medical records, 67 00:02:52,406 --> 00:02:55,150 this patient holds the longest record for CPR survival: 68 00:02:55,150 --> 00:02:57,291 4 hours. 69 00:02:57,291 --> 00:03:00,766 CPR was performed on him from Cathay General Hospital to NTU Hospital. 70 00:03:00,766 --> 00:03:02,808 When physicians tried ECMO technique at the NTU hospital, 71 00:03:02,808 --> 00:03:05,015 they found that over 100 doses 72 00:03:05,015 --> 00:03:06,683 of cardiotonic drugs 73 00:03:06,683 --> 00:03:08,746 were already given to him. 74 00:03:08,746 --> 00:03:10,303 When an incision was made 75 00:03:10,303 --> 00:03:10,947 to insert an ECMO tube, 76 00:03:10,947 --> 00:03:12,408 the patient's veins and arteries were too narrow. 77 00:03:12,408 --> 00:03:13,636 Therefore, CPR had to be conducted again 78 00:03:13,636 --> 00:03:14,879 until he was in the operating room. 79 00:03:14,879 --> 00:03:15,807 Surgeons had to saw open the patient's chest 80 00:03:15,807 --> 00:03:18,192 to insert ECMO tubes from the top. 81 00:03:18,192 --> 00:03:22,448 The entire procedure sounds surreal right now. 82 00:03:22,448 --> 00:03:27,160 Every time I recall this case, I always say it's a modern medical miracle. 83 00:03:27,160 --> 00:03:30,330 The fact that a man‘s heart had stopped for 9 days. 84 00:03:30,330 --> 00:03:34,100 And after enduring heart and kidney transplants, 85 00:03:34,100 --> 00:03:36,728 a 4 hour CPR, 86 00:03:36,728 --> 00:03:39,169 he could still survive. 87 00:03:39,169 --> 00:03:40,871 Here is anthother patient case. 88 00:03:40,871 --> 00:03:42,516 The headline reads ”World's First: 89 00:03:42,516 --> 00:03:43,943 Miracle of Taiwan". 90 00:03:43,943 --> 00:03:46,421 Man without heart for 16 days. 91 00:03:46,421 --> 00:03:49,746 In this case, the patient is a 56-year-old man. 92 00:03:49,746 --> 00:03:51,346 He had a tooth decay. 93 00:03:51,346 --> 00:03:53,396 Bacteria from the cavity went into the blood, 94 00:03:53,396 --> 00:03:54,297 and spread to the portions of the heart. 95 00:03:54,297 --> 00:03:55,885 It caused a pus buildup. 96 00:03:55,885 --> 00:03:57,824 The patient went to a different hospital 97 00:03:57,824 --> 00:03:59,761 where the surgical team opened up his chest, 98 00:03:59,761 --> 00:04:00,561 and began to eliminate 99 00:04:00,561 --> 00:04:01,945 infected tissues of the heart. 100 00:04:01,945 --> 00:04:02,796 The team continued to remove 101 00:04:02,796 --> 00:04:03,849 more affected tissues 102 00:04:03,849 --> 00:04:06,866 until not much of the muscular organ was left. 103 00:04:06,866 --> 00:04:07,861 So what can the team do now? 104 00:04:07,861 --> 00:04:13,267 Transfer this patient to NTU hospital. 105 00:04:13,308 --> 00:04:17,128 It seems that NTU hospital is the last line of medical defense in Taiwan. 106 00:04:17,128 --> 00:04:18,990 NTU hospital has to take patients in. 107 00:04:18,990 --> 00:04:21,831 In the first case, the case was cardiac arrest. 108 00:04:21,831 --> 00:04:22,543 This case is more extreme. 109 00:04:22,543 --> 00:04:23,779 This is a man with not much of a heart left. 110 00:04:23,779 --> 00:04:25,475 It was almost all surgically removed. 111 00:04:25,475 --> 00:04:26,706 When the patient was transferred to NTU hospital, 112 00:04:26,706 --> 00:04:28,527 because of the state he was in, 113 00:04:28,527 --> 00:04:30,254 our medical team had to use two ECMOs. 114 00:04:30,254 --> 00:04:31,241 Look at this slide. 115 00:04:31,241 --> 00:04:32,733 There are two ECMO devices. 116 00:04:32,733 --> 00:04:34,376 This one is even more unbelievable. 117 00:04:34,376 --> 00:04:35,511 Since he didn't have a heart left, 118 00:04:35,511 --> 00:04:37,747 so the ECG displayed a completely flat line. 119 00:04:37,747 --> 00:04:40,880 There's not much to explain here. 120 00:04:40,880 --> 00:04:42,432 This is his CT scan result. 121 00:04:42,432 --> 00:04:43,285 Theoretically, 122 00:04:43,285 --> 00:04:45,915 there should have been a heart in his thorax. 123 00:04:45,915 --> 00:04:47,030 However, the heart is missing here. 124 00:04:47,030 --> 00:04:49,390 There are only tubes. 125 00:04:49,390 --> 00:04:51,285 After 16 days, 126 00:04:51,285 --> 00:04:53,485 our surgical team performed a heart transplant surgery on this patient. 127 00:04:53,485 --> 00:04:56,408 Cardiologist surgeon Dr. Wan showed me this. 128 00:04:56,408 --> 00:04:58,472 Dr. Wan said during the surgery, 129 00:04:58,472 --> 00:04:59,494 he opened the patient's chest 130 00:04:59,494 --> 00:05:01,938 and had expected a heart in the thorax. 131 00:05:01,938 --> 00:05:03,830 However, there were only plastic tubes 132 00:05:03,830 --> 00:05:06,634 connecting to the ECMO. 133 00:05:06,634 --> 00:05:09,179 The patient had no heart at all. 134 00:05:09,179 --> 00:05:12,196 And after 16 days, the heart transplant surgery was completed. 135 00:05:12,196 --> 00:05:15,317 The patient was discharged later. 136 00:05:15,317 --> 00:05:18,834 Here is the Straits Times of Singapore. 137 00:05:18,834 --> 00:05:22,161 A vendor I know sent me an e-mail from Singapore. 138 00:05:22,161 --> 00:05:24,590 He told me that we were featured in the Straits Times. 139 00:05:24,590 --> 00:05:26,329 16 days without heart 140 00:05:26,329 --> 00:05:27,989 A person had lived for 16 days without a heart. 141 00:05:27,989 --> 00:05:29,219 But after receiving heart transplant, 142 00:05:29,219 --> 00:05:33,337 he still went home in good shape. 143 00:05:33,337 --> 00:05:35,103 This is a third case. 144 00:05:35,103 --> 00:05:39,209 He’s a 26-year-old aboriginal Taiwanese. 145 00:05:39,209 --> 00:05:41,370 He went swimming even when he was seriously drunk. 146 00:05:41,370 --> 00:05:45,080 Jokingly, he probably thought he was Li Bai the poet. 147 00:05:45,080 --> 00:05:47,175 The pond he swam in was really unsanitary. 148 00:05:47,175 --> 00:05:48,217 He choked on water. 149 00:05:48,217 --> 00:05:49,618 As a result, 150 00:05:49,618 --> 00:05:51,410 he caught a severe case of pneumonia. 151 00:05:51,410 --> 00:05:53,393 He’d relied on ECMO for 117 days. 152 00:05:53,393 --> 00:05:55,187 Look at his lungs. 153 00:05:55,187 --> 00:05:55,976 After he ingested unclean water, 154 00:05:55,976 --> 00:05:57,380 his condition worsened to a severe case of pneumonia. 155 00:05:57,380 --> 00:05:59,818 This is called acute respiratory distress syndrome. 156 00:05:59,818 --> 00:06:01,948 The lungs became abnormally white. 157 00:06:01,948 --> 00:06:05,090 He lived on ECMO for 117 days. 158 00:06:05,090 --> 00:06:09,524 We can see clearly from this slide. 159 00:06:09,524 --> 00:06:11,860 For one entire month, 160 00:06:11,860 --> 00:06:13,486 the patient's ventilation volume 161 00:06:13,486 --> 00:06:15,155 did not exceed 100 c.c. 162 00:06:15,155 --> 00:06:18,018 But the patient still recovered. 163 00:06:18,018 --> 00:06:19,459 In short, 164 00:06:19,459 --> 00:06:21,226 in the these three medical cases, 165 00:06:21,226 --> 00:06:22,961 in the these three medical cases, 166 00:06:22,961 --> 00:06:24,606 the patient undergoing cardiac arrest, 167 00:06:24,606 --> 00:06:27,110 or the patient with lung failure, 168 00:06:27,110 --> 00:06:29,308 with the help of ECMO, 169 00:06:29,308 --> 00:06:32,590 no matter whether 9 days later 170 00:06:32,590 --> 00:06:34,605 or even 100 days afterwards, 171 00:06:34,605 --> 00:06:36,373 after a heart transplant 172 00:06:36,373 --> 00:06:37,832 or lung transplant, 173 00:06:37,832 --> 00:06:39,519 their lives were saved. 174 00:06:39,519 --> 00:06:41,629 It is really incredible. 175 00:06:41,629 --> 00:06:42,823 To be honest... 176 00:06:42,823 --> 00:06:44,578 In recent history, ECMO has retained 177 00:06:44,578 --> 00:06:45,728 a high level of awareness 178 00:06:45,728 --> 00:06:47,664 thanks to the media presses in Taiwan. 179 00:06:47,664 --> 00:06:48,695 The reason why folks know about ECMO, 180 00:06:48,695 --> 00:06:50,572 is because of past success cases, 181 00:06:50,572 --> 00:06:52,259 and also because of the first lady in Taichung, 182 00:06:52,259 --> 00:06:53,761 and famed astrologer Nick Yen. 183 00:06:53,761 --> 00:06:55,333 However, 184 00:06:55,333 --> 00:06:56,403 the media usually 185 00:06:56,403 --> 00:06:58,211 only reports on the successful stories. 186 00:06:58,211 --> 00:06:59,408 Reporters don’t write failed cases. 187 00:06:59,408 --> 00:07:00,942 Hidden from the public eye. 188 00:07:00,942 --> 00:07:04,117 As a critical care physician, 189 00:07:04,117 --> 00:07:06,322 I am certainly glad to encounter successful patient cases. 190 00:07:06,322 --> 00:07:08,187 However, there are cases that are not as successful. 191 00:07:08,187 --> 00:07:12,953 This baby was one and half months old. 192 00:07:12,953 --> 00:07:14,767 He suffered from a congenital heart disease. 193 00:07:14,767 --> 00:07:16,324 After undergoing a heart surgery, 194 00:07:16,324 --> 00:07:17,886 the baby still could not live without a heart-lung machine. 195 00:07:17,886 --> 00:07:19,643 So, we hooked the baby up to an ECMO. 196 00:07:19,643 --> 00:07:20,668 The ECMO was inserted in the baby's heart. 197 00:07:20,668 --> 00:07:21,965 After the procedure, 198 00:07:21,965 --> 00:07:22,989 in three days, 199 00:07:22,989 --> 00:07:24,209 the baby's feet turned black. 200 00:07:24,209 --> 00:07:25,379 Let’s zoom in. 201 00:07:25,379 --> 00:07:27,028 Look at his tiny, blackened feet. 202 00:07:27,028 --> 00:07:28,488 So now, as a physician, 203 00:07:28,488 --> 00:07:29,993 you have to make a decision. 204 00:07:29,993 --> 00:07:31,510 Should you amputate his tiny feet 205 00:07:31,510 --> 00:07:32,615 to try to save his life? 206 00:07:32,615 --> 00:07:33,580 Or should you just give up 207 00:07:33,580 --> 00:07:34,835 and let him go? 208 00:07:34,835 --> 00:07:37,695 These types of decisions are incredibly stressful to make. 209 00:07:37,695 --> 00:07:40,091 But if you can’t make the call, 210 00:07:40,091 --> 00:07:42,114 then the next case is more difficult to gauge. 211 00:07:42,114 --> 00:07:44,830 Here is a 7-year-old boy 212 00:07:44,830 --> 00:07:46,151 suffering from streptococcus pneumonia. 213 00:07:46,151 --> 00:07:48,962 His condition worsened to acute respiratory distress syndrome. 214 00:07:48,962 --> 00:07:51,538 So the medical team decided to employ ECMO technique. 215 00:07:51,538 --> 00:07:53,829 After using ECMO, however, 216 00:07:53,829 --> 00:07:55,044 there were complications. 217 00:07:55,044 --> 00:07:56,889 His limbs all turned black. 218 00:07:56,889 --> 00:07:58,493 His adorable eyes would look at you, 219 00:07:58,493 --> 00:07:59,316 his conscious in a clear state. 220 00:07:59,316 --> 00:08:00,711 He could even ask for water when he was thirsty. 221 00:08:00,711 --> 00:08:02,645 But as a doctor, 222 00:08:02,645 --> 00:08:04,540 you have to make incredibly hard decisions. 223 00:08:04,540 --> 00:08:05,963 If you want to save him, 224 00:08:05,963 --> 00:08:07,541 you have to cut off his limbs first, 225 00:08:07,541 --> 00:08:08,983 and continue with further medical treatment. 226 00:08:08,983 --> 00:08:10,868 And if you give up, 227 00:08:10,868 --> 00:08:12,332 you have to turn off the ECMO. 228 00:08:12,332 --> 00:08:14,080 Now think of this: 229 00:08:14,080 --> 00:08:16,298 Between life and death, 230 00:08:16,298 --> 00:08:17,801 when the patient is in a conscious state, 231 00:08:17,801 --> 00:08:21,887 of course, the doctor's mind is clear, too. 232 00:08:21,887 --> 00:08:23,788 How would you ask the boy? 233 00:08:23,788 --> 00:08:24,883 "Hi dear" 234 00:08:24,883 --> 00:08:26,589 "If you want to live" 235 00:08:26,589 --> 00:08:28,493 "I will need to amputate your limbs." 236 00:08:28,493 --> 00:08:30,400 "Or you'd rather give up," 237 00:08:30,400 --> 00:08:32,397 "and rest in peace?" 238 00:08:32,397 --> 00:08:34,421 How do you communicate this type of life and death decision 239 00:08:34,421 --> 00:08:37,569 with a 7-year-old? 240 00:08:37,569 --> 00:08:39,646 This is the line of work I have to deal with 241 00:08:39,646 --> 00:08:41,723 as a critical care physician. 242 00:08:41,723 --> 00:08:43,800 In the beginning, I made decisions rather logically. 243 00:08:43,800 --> 00:08:47,368 I identified everything by patients. 244 00:08:47,368 --> 00:08:48,652 Gradually, 245 00:08:48,652 --> 00:08:49,843 I targeted diseases, not patients. 246 00:08:49,843 --> 00:08:51,260 A diseased heart, for example. 247 00:08:51,260 --> 00:08:53,123 Fortunately, when I turned fifty, 248 00:08:53,123 --> 00:08:56,585 I gradually realized that I should treat patient as a whole again. 249 00:08:56,585 --> 00:08:58,079 To be quite honest, 250 00:08:58,079 --> 00:09:00,505 I consider myself academically inclined. 251 00:09:00,505 --> 00:09:02,089 When I reached my 30s, 252 00:09:02,089 --> 00:09:03,057 heart transplants, 253 00:09:03,057 --> 00:09:04,067 lung transplants, 254 00:09:04,067 --> 00:09:05,138 ECMO technique, 255 00:09:05,138 --> 00:09:07,888 youngest chief physician in NTU hospital, 256 00:09:07,888 --> 00:09:09,517 chief physician of the Surgical Intensive Care Unit, 257 00:09:09,517 --> 00:09:11,919 Initiated the Organ Registry and Sharing Center project, 258 00:09:11,919 --> 00:09:13,136 Chief physician of the Trauma Unit. 259 00:09:13,136 --> 00:09:15,740 All these were accomplished by my 30s. 260 00:09:15,740 --> 00:09:17,207 During this journey, 261 00:09:17,207 --> 00:09:20,140 I believed that medical knowledge was incredibly powerful. 262 00:09:20,140 --> 00:09:21,678 Medical knowledge can cure everything. 263 00:09:21,678 --> 00:09:23,982 But in my 40s, 264 00:09:23,982 --> 00:09:25,414 there were many unsuccessful cases 265 00:09:25,414 --> 00:09:27,116 with the use of ECMO. 266 00:09:27,116 --> 00:09:28,052 Sometimes the families of the patients asked me, 267 00:09:28,052 --> 00:09:29,239 “How come the First Lady of Taichung survived, 268 00:09:29,239 --> 00:09:31,926 but my family member didn't make it?” 269 00:09:31,926 --> 00:09:33,220 I don’t know how to answer such questions. 270 00:09:33,220 --> 00:09:36,495 I couldn’t say because he or she was not the First Lady, could I? 271 00:09:36,495 --> 00:09:37,390 Others ask me, 272 00:09:37,390 --> 00:09:39,234 “why do his limbs turned black?” 273 00:09:39,234 --> 00:09:40,131 If I'd known the answer, 274 00:09:40,131 --> 00:09:41,048 I would have definitely prevented it from happening. 275 00:09:41,048 --> 00:09:42,354 I have to admit that I don't know. 276 00:09:42,354 --> 00:09:44,440 So when I was in my 40s, 277 00:09:44,440 --> 00:09:46,487 I thought that 278 00:09:46,487 --> 00:09:49,553 why couldn't this patient be saved? 279 00:09:49,553 --> 00:09:51,557 Finally, when I was reached my 50s, 280 00:09:51,557 --> 00:09:54,057 the concept dawned on me. 281 00:09:54,057 --> 00:09:56,661 There's a Chinese poetry that says: "I've searched high and low for her." 282 00:09:56,661 --> 00:09:57,533 "It's only when I turned around," 283 00:09:57,533 --> 00:09:59,652 "The woman I seek is just standing behind me near a lantern." 284 00:09:59,652 --> 00:10:00,439 That day, 285 00:10:00,439 --> 00:10:01,880 it dawned on me that 286 00:10:01,880 --> 00:10:04,143 doctors are people, not God. 287 00:10:04,143 --> 00:10:05,262 Doctors can only try our best. 288 00:10:05,262 --> 00:10:08,058 That’s it. 289 00:10:08,058 --> 00:10:10,284 I began to reason this philosophy out. 290 00:10:10,284 --> 00:10:11,144 Let's look at seasons. 291 00:10:11,144 --> 00:10:13,199 There's spring, summer, autumn, and winter. 292 00:10:13,199 --> 00:10:15,449 Medicine has its limit. 293 00:10:15,449 --> 00:10:18,010 No matter how advanced science is, 294 00:10:18,010 --> 00:10:19,243 with today’s technology, 295 00:10:19,243 --> 00:10:19,921 a person without a heart, 296 00:10:19,921 --> 00:10:20,497 or lungs, 297 00:10:20,497 --> 00:10:21,530 or liver, 298 00:10:21,530 --> 00:10:21,894 or kidney, 299 00:10:21,894 --> 00:10:23,168 can still live. 300 00:10:23,168 --> 00:10:26,162 But can we replace our organs with devices or gadgets 301 00:10:26,162 --> 00:10:27,981 forever? 302 00:10:27,981 --> 00:10:30,493 Medicine still has its limits. 303 00:10:30,493 --> 00:10:32,696 So I came to a conclusion. 304 00:10:32,696 --> 00:10:35,604 Can gardeners change the seasons? 305 00:10:35,604 --> 00:10:37,168 Of course not. 306 00:10:37,168 --> 00:10:39,070 Gardeners can only make flowers 307 00:10:39,070 --> 00:10:42,221 grow prettier in the four seasons. 308 00:10:42,221 --> 00:10:43,490 As a doctor, 309 00:10:43,490 --> 00:10:45,806 am I capable of changing nature's rules to birth, aging, sickness or death? 310 00:10:45,806 --> 00:10:46,731 Well, 311 00:10:46,731 --> 00:10:47,990 it's very difficult. 312 00:10:47,990 --> 00:10:49,455 As a doctor, 313 00:10:49,455 --> 00:10:52,358 all we can do is to enable people 314 00:10:52,358 --> 00:10:53,692 to go through life a little easier when they’re alive. 315 00:10:53,692 --> 00:10:54,557 That’s all. 316 00:10:54,557 --> 00:10:55,356 So gradually, 317 00:10:55,356 --> 00:10:57,114 I came to realize that 318 00:10:57,114 --> 00:11:01,231 doctors are just the gardeners in the life's garden. 319 00:11:01,231 --> 00:11:05,380 As a gardener, 320 00:11:05,380 --> 00:11:07,308 when faced with the withered plants, 321 00:11:07,308 --> 00:11:09,070 how to treat them is a great question. 322 00:11:09,070 --> 00:11:11,563 As an expert in critical care, 323 00:11:11,563 --> 00:11:14,931 how do I face death? 324 00:11:14,931 --> 00:11:16,884 From a scientific aspect, 325 00:11:16,884 --> 00:11:19,289 or more precisely, from molecular science, 326 00:11:19,289 --> 00:11:20,615 a system undergoing physical reaction 327 00:11:20,615 --> 00:11:21,548 on a molecular level 328 00:11:21,548 --> 00:11:22,398 will tend to minimize energy 329 00:11:22,398 --> 00:11:23,418 and maximize entropy. 330 00:11:23,418 --> 00:11:26,607 So delta S (entropy) should be greater or equal to zero. 331 00:11:26,607 --> 00:11:29,524 Some may ask how delta s is greater than zero. 332 00:11:29,524 --> 00:11:31,317 Some believe it's from the Big Bang theory, 333 00:11:31,317 --> 00:11:33,748 as it describes the state of ever-expanding universe. 334 00:11:33,748 --> 00:11:35,827 So that's how delta S is greater than zero. 335 00:11:35,827 --> 00:11:36,697 Or you may ask, 336 00:11:36,697 --> 00:11:38,784 is anything constant in the laws of this universe? 337 00:11:38,784 --> 00:11:39,353 Honestly, 338 00:11:39,353 --> 00:11:40,244 I don’t have an answer to this. 339 00:11:40,244 --> 00:11:41,720 There’s an old saying 340 00:11:41,720 --> 00:11:46,173 "A blind man is no judge of colors." 341 00:11:46,173 --> 00:11:47,329 Visually impared folks 342 00:11:47,329 --> 00:11:48,644 can’t distinguish colors 343 00:11:48,644 --> 00:11:50,435 so it's pointless to ask them to judge. 344 00:11:50,435 --> 00:11:52,263 Does constant apply 345 00:11:52,263 --> 00:11:53,449 to the laws in this universe? 346 00:11:53,449 --> 00:11:55,297 Does eternity exist 347 00:11:55,297 --> 00:11:55,993 in space and time? 348 00:11:55,993 --> 00:11:56,483 Frankly, 349 00:11:56,483 --> 00:11:57,535 I don’t know these answers. 350 00:11:57,535 --> 00:11:58,562 But at least, 351 00:11:58,562 --> 00:12:00,605 within the realm of our discussion 352 00:12:00,605 --> 00:12:02,618 delta S is still positive. 353 00:12:02,618 --> 00:12:04,490 What does it mean when we say delta S is positive? 354 00:12:04,490 --> 00:12:05,295 In theory, 355 00:12:05,295 --> 00:12:07,157 objects tends to be in minimum energy and maximum entropy, 356 00:12:07,157 --> 00:12:08,176 creating greater disorder. 357 00:12:08,176 --> 00:12:10,140 My existence 358 00:12:10,140 --> 00:12:11,361 would mean a delta S less than zero, 359 00:12:11,361 --> 00:12:14,958 which defies molecular science. 360 00:12:14,958 --> 00:12:17,202 Then how should we view life and death? 361 00:12:17,202 --> 00:12:18,611 Actually, 362 00:12:18,611 --> 00:12:20,682 we often see ourselves only. 363 00:12:20,682 --> 00:12:22,601 We don’t realize that we are in the universe. 364 00:12:22,601 --> 00:12:24,923 The universe is the combination of us and the environment. 365 00:12:24,923 --> 00:12:26,347 So total delta S 366 00:12:26,347 --> 00:12:29,446 equals to delta S system and delta S surrounding. 367 00:12:29,446 --> 00:12:30,437 So 368 00:12:30,437 --> 00:12:32,631 this is an important concept. 369 00:12:32,631 --> 00:12:35,202 Any organized group 370 00:12:35,202 --> 00:12:37,240 is always in an unstable state. 371 00:12:37,240 --> 00:12:39,428 The group disrupts its surrounding. 372 00:12:39,428 --> 00:12:41,178 So even if delta S for the group is negative, 373 00:12:41,178 --> 00:12:43,284 because the group disrupts its surrounding, 374 00:12:43,284 --> 00:12:44,561 delta S total is greater than zero 375 00:12:44,561 --> 00:12:46,361 to make the equation positive. 376 00:12:46,361 --> 00:12:47,188 So my existence 377 00:12:47,188 --> 00:12:49,326 is to disrupt my surroundings 378 00:12:49,326 --> 00:12:50,298 until one day 379 00:12:50,298 --> 00:12:52,062 when I can no longer do so, 380 00:12:52,062 --> 00:12:53,659 that's when I disrupt myself 381 00:12:53,659 --> 00:12:56,399 so Delta S total can remain positive. 382 00:12:56,399 --> 00:12:58,207 In essence, our existence is to disrupt. 383 00:12:58,207 --> 00:12:59,268 When you’re unable to disrupt the surrounding, 384 00:12:59,268 --> 00:13:00,311 you end up disrupting yourself. 385 00:13:00,311 --> 00:13:01,635 That is the meaning of death. 386 00:13:01,635 --> 00:13:04,917 It's death from a molecular science aspect. 387 00:13:04,917 --> 00:13:07,544 However, 388 00:13:07,544 --> 00:13:08,797 as a doctor, 389 00:13:08,797 --> 00:13:10,885 I understand molecular science. 390 00:13:10,885 --> 00:13:13,159 But what about the meaning of life? 391 00:13:13,159 --> 00:13:14,758 One day, when I was in ICU 392 00:13:14,758 --> 00:13:15,620 making my rounds 393 00:13:15,620 --> 00:13:16,907 I came to realize 394 00:13:16,907 --> 00:13:18,623 that humans only have two types of ending. 395 00:13:18,623 --> 00:13:19,286 One is with inserted tubes. 396 00:13:19,286 --> 00:13:21,529 The other is without. 397 00:13:21,529 --> 00:13:24,340 Both represent death. 398 00:13:24,340 --> 00:13:26,855 Death is every person's final journey. 399 00:13:26,855 --> 00:13:27,804 So 400 00:13:27,804 --> 00:13:30,780 what does death mean to us? 401 00:13:30,780 --> 00:13:33,692 I'd like to share a contrasting viewpoint on this. 402 00:13:33,692 --> 00:13:35,840 If you ask me what death is, 403 00:13:35,840 --> 00:13:37,486 I will ask you: 404 00:13:37,486 --> 00:13:40,495 what does it mean to be alive? 405 00:13:40,495 --> 00:13:41,452 Everyone here in this audience 406 00:13:41,452 --> 00:13:43,149 came to hear a lecture. 407 00:13:43,149 --> 00:13:45,157 I hope you can do one thing when you leave. 408 00:13:45,157 --> 00:13:46,567 Before falling asleep tonight, 409 00:13:46,567 --> 00:13:47,433 when you’re lying on your bed, 410 00:13:47,433 --> 00:13:49,017 ask yourself this question: 411 00:13:49,017 --> 00:13:58,424 "What does it mean to be alive?" 412 00:13:58,424 --> 00:13:59,208 Because 413 00:13:59,208 --> 00:14:00,621 this question 414 00:14:00,621 --> 00:14:02,552 leads us to contemplate 415 00:14:02,552 --> 00:14:03,831 on the meaning of life. 416 00:14:03,831 --> 00:14:05,909 My answer to the question is this: 417 00:14:05,909 --> 00:14:07,168 "When you’re searching for the answer to the question, 418 00:14:07,168 --> 00:14:10,508 it is the answer to the question." 419 00:14:10,508 --> 00:14:12,331 Everyone dies eventually. 420 00:14:12,331 --> 00:14:14,200 No one will set death 421 00:14:14,200 --> 00:14:15,404 as his or her goal in life. 422 00:14:15,404 --> 00:14:17,299 Therefore, life is just a process. 423 00:14:17,299 --> 00:14:20,082 In this process 424 00:14:20,082 --> 00:14:21,371 during one's entire lifespan 425 00:14:21,371 --> 00:14:23,530 we keep searching for the answer 426 00:14:23,530 --> 00:14:25,133 to the meaning of existence. 427 00:14:25,133 --> 00:14:27,403 So when you’re searching for the answer to existence 428 00:14:27,403 --> 00:14:29,042 that is the very answer to the question. 429 00:14:29,042 --> 00:14:31,249 Death is not the goal of life. 430 00:14:31,249 --> 00:14:33,491 Life is just a process. 431 00:14:33,491 --> 00:14:37,558 Recently, I've been sharing the story of feces. 432 00:14:37,558 --> 00:14:39,110 At one time, my advisor was going to retire. 433 00:14:39,110 --> 00:14:39,673 So he said, 434 00:14:39,673 --> 00:14:40,556 "I am going to retire, 435 00:14:40,556 --> 00:14:41,375 treat me to somewhere fancy." 436 00:14:41,375 --> 00:14:42,480 I said, "Of course." 437 00:14:42,480 --> 00:14:44,389 So my advisor, another schoolmate, and I 438 00:14:44,389 --> 00:14:46,503 went to the 2nd floor of the Sheraton Hotel 439 00:14:46,503 --> 00:14:48,959 to celebrate in a French restaurant. 440 00:14:48,959 --> 00:14:51,654 The three of us spent TWD$ 26,000. 441 00:14:51,654 --> 00:14:54,397 I was astonished when I got the bill. 442 00:14:54,397 --> 00:14:56,010 How could I eat something so expensive? 443 00:14:56,010 --> 00:14:57,909 I’d never been to that kind of restaurant before, 444 00:14:57,909 --> 00:14:58,596 so we ordered 445 00:14:58,596 --> 00:14:59,993 some random and unknown dishes. 446 00:14:59,993 --> 00:15:01,369 When I saw the bill, 447 00:15:01,369 --> 00:15:03,168 TWD$ 26,000, I was too shocked to speak. 448 00:15:03,168 --> 00:15:04,927 The next morning, in the toilet, 449 00:15:04,927 --> 00:15:09,081 I examined my feces carefully. 450 00:15:09,081 --> 00:15:10,606 I thought in my mind, 451 00:15:10,606 --> 00:15:15,390 "I’d spent TWD$ 9,000 dollars producing this." 452 00:15:15,390 --> 00:15:15,909 After careful examination, I concluded that 453 00:15:15,909 --> 00:15:18,394 this "poo" looks no different from the feces I produced after dining in the NTU hospital cafeteria. 454 00:15:18,394 --> 00:15:19,800 The buffet there costs TWD$ 70 only. 455 00:15:19,800 --> 00:15:23,550 I couldn't tell the difference. 456 00:15:23,550 --> 00:15:26,659 On the toilet, I came to realize that 457 00:15:26,659 --> 00:15:28,606 all the wealth one desires 458 00:15:28,606 --> 00:15:35,666 turns out to be crap. 459 00:15:40,074 --> 00:15:43,061 Confucianism is the most important philosophical system in the Chinese culture. 460 00:15:43,077 --> 00:15:45,613 The advantages of Confucianism are that 461 00:15:45,613 --> 00:15:48,047 its philosophy is about human virtues. 462 00:15:48,047 --> 00:15:50,254 Let's look at a few passages 463 00:15:50,254 --> 00:15:51,104 in the Analects of Confucius. 464 00:15:51,104 --> 00:15:52,455 "“If you don't understand what life is, how will you understand death?" 465 00:15:52,455 --> 00:15:53,059 "If you can't yet serve men," 466 00:15:53,059 --> 00:15:54,474 "how can you serve the spirits?” 467 00:15:54,474 --> 00:15:55,223 “When your parents are alive," 468 00:15:55,223 --> 00:15:55,624 "serve them with propriety;" 469 00:15:55,624 --> 00:15:56,015 "when they die," 470 00:15:56,015 --> 00:15:56,921 "bury them with propriety," 471 00:15:56,921 --> 00:15:58,320 "and then worship them with propriety." 472 00:15:58,320 --> 00:15:59,975 Confucianism refused to talk about life and death. 473 00:15:59,975 --> 00:16:00,955 Instead, Confucius gave answers to 474 00:16:00,955 --> 00:16:02,620 sacrificing life for justice 475 00:16:02,620 --> 00:16:04,293 and how man holds no regret 476 00:16:04,293 --> 00:16:06,653 once he understands "the way". 477 00:16:06,653 --> 00:16:09,508 To a follower of Confucianism, the question of life and death 478 00:16:09,508 --> 00:16:11,074 is a topic to be avoided. 479 00:16:11,074 --> 00:16:12,281 He offered no direct answers. 480 00:16:12,281 --> 00:16:14,439 So... 481 00:16:14,439 --> 00:16:15,292 on the positive side, 482 00:16:15,292 --> 00:16:15,986 he focuses on the time when he is alive. 483 00:16:15,986 --> 00:16:17,812 Just avoid these big questions 484 00:16:17,812 --> 00:16:19,564 and focus on the things you have at hand. 485 00:16:19,564 --> 00:16:20,551 But there is one problem. 486 00:16:20,551 --> 00:16:23,685 He totally sidesteps the question of life and death. 487 00:16:23,685 --> 00:16:26,098 The following is what I think. 488 00:16:26,098 --> 00:16:27,749 In Chinese culture, 489 00:16:27,749 --> 00:16:29,722 Confucianism is the most crucial philosophy. 490 00:16:29,722 --> 00:16:31,506 Back then, our forefathers didn't want to discuss life and death. 491 00:16:31,506 --> 00:16:33,372 They tried to avoid the question. 492 00:16:33,372 --> 00:16:36,354 There’s a saying from Sun Tzu's Art of War: 493 00:16:36,354 --> 00:16:38,198 "Force soldiers to see the face of death; they will fight to stay alive." 494 00:16:38,198 --> 00:16:40,219 Only when we can face death 495 00:16:40,219 --> 00:16:42,735 or even face death straight up 496 00:16:42,735 --> 00:16:45,724 can we begin to reflect on 497 00:16:45,724 --> 00:16:47,234 what life is. 498 00:16:47,234 --> 00:16:49,549 We will all die one day. 499 00:16:49,549 --> 00:16:51,760 Life is just a process, 500 00:16:51,760 --> 00:16:55,428 a process of searching for the meaning of existence. 501 00:16:55,428 --> 00:16:57,351 That's just my humble opinion. 502 00:16:57,351 --> 00:16:58,845 I think I can be considered an astute person. 503 00:16:58,845 --> 00:17:00,571 My stamina is good, too. 504 00:17:00,571 --> 00:17:03,362 I've biked around the entire Taiwan island on my first biking tour. 505 00:17:03,362 --> 00:17:05,459 Just because I'm asute 506 00:17:05,459 --> 00:17:07,231 and also in good physical shape, 507 00:17:07,231 --> 00:17:09,225 can I use these blessings 508 00:17:09,225 --> 00:17:10,153 to bully 509 00:17:10,153 --> 00:17:11,317 or to take advantage of others? 510 00:17:11,317 --> 00:17:12,127 Definitely not. 511 00:17:12,127 --> 00:17:12,815 So 512 00:17:12,815 --> 00:17:14,870 those who are blessed 513 00:17:14,870 --> 00:17:16,527 should be grateful. 514 00:17:16,527 --> 00:17:18,480 If we are very capable, 515 00:17:18,480 --> 00:17:20,088 shouldn't we actively help others 516 00:17:20,088 --> 00:17:22,717 and make our lives more meaningful? 517 00:17:22,717 --> 00:17:23,861 Life is about "knowing gratitude" and "repaying gratitude." 518 00:17:23,861 --> 00:17:25,832 When I visited Dharma Drum Mountain Monastery, 519 00:17:25,832 --> 00:17:27,717 the abbot there, Veneralble Guo-Dong, shared with me 520 00:17:27,717 --> 00:17:28,709 the idea of "knowing and repaying gratitude," 521 00:17:28,709 --> 00:17:29,568 as well as "being grateful, not resentful." 522 00:17:29,568 --> 00:17:31,245 He said, 523 00:17:31,245 --> 00:17:32,530 “I know you've been wronged,” 524 00:17:32,530 --> 00:17:34,504 “but you can’t complain." 525 00:17:34,504 --> 00:17:38,666 "Instead, you should make greater vows to help others in need.” 526 00:17:38,666 --> 00:17:40,659 Lastly, let me share a concept 527 00:17:40,659 --> 00:17:42,430 called “a to the power of n.” 528 00:17:42,430 --> 00:17:44,080 If "a" is greater than 1, 529 00:17:44,080 --> 00:17:45,442 "a" to the power of "n" is infinity. 530 00:17:45,442 --> 00:17:46,679 If "a" is less than 1, 531 00:17:46,679 --> 00:17:48,282 "a" to the power of "n" will approach zero rapidly. 532 00:17:48,282 --> 00:17:49,763 What does that mean? 533 00:17:49,763 --> 00:17:52,543 If what I give to the society 534 00:17:52,543 --> 00:17:54,062 is greater than what I take from the society, 535 00:17:54,062 --> 00:17:55,283 my "a" is greater than one. 536 00:17:55,283 --> 00:17:57,256 This society will become better and better accordingly. 537 00:17:57,256 --> 00:17:58,801 If what I take from the society 538 00:17:58,801 --> 00:18:00,488 is greater than what I give to the society, 539 00:18:00,488 --> 00:18:01,642 my "a" will be less than 1. 540 00:18:01,642 --> 00:18:03,431 Consequently, this society will increasingly collapse. 541 00:18:03,431 --> 00:18:05,419 I will end my speech 542 00:18:05,419 --> 00:18:07,295 with these words. 543 00:18:07,295 --> 00:18:09,415 "Facing hardships is not the most difficult thing." 544 00:18:09,415 --> 00:18:11,167 "The most difficult thing is..." 545 00:18:11,167 --> 00:18:12,784 "to facing the hardships" 546 00:18:12,784 --> 00:18:14,241 "without loosing your passion for mankind." 547 00:18:14,241 --> 00:18:16,177 Thank you, everyone!