1 00:00:09,339 --> 00:00:12,025 The human eye is an amazing mechanism, 2 00:00:12,025 --> 00:00:16,465 able to detect anywhere from a few photons to direct sunlight, 3 00:00:16,465 --> 00:00:19,081 or switch focus from the screen in front of you 4 00:00:19,081 --> 00:00:22,631 to the distant horizon in a third of a second. 5 00:00:22,631 --> 00:00:26,359 In fact, the structures required for such incredible flexibility 6 00:00:26,359 --> 00:00:28,368 were once considered so complex 7 00:00:28,368 --> 00:00:33,499 that Charles Darwin himself acknowledged that the idea of their having evolved 8 00:00:33,499 --> 00:00:37,456 seemed absurd in the highest possible degree. 9 00:00:37,456 --> 00:00:42,981 And yet, that is exactly what happened, starting more than 500 million years ago. 10 00:00:42,981 --> 00:00:46,762 The story of the human eye begins with a simple light spot, 11 00:00:46,762 --> 00:00:49,815 such as the one found in single-celled organisms, 12 00:00:49,815 --> 00:00:51,622 like euglena. 13 00:00:51,622 --> 00:00:53,843 This is a cluster of light-sensitive proteins 14 00:00:53,843 --> 00:00:56,412 linked to the organism's flagellum, 15 00:00:56,412 --> 00:01:00,022 activating when it finds light, and therefore food. 16 00:01:00,022 --> 00:01:05,037 A more complex version of this light spot can be found in the flat worm, planaria. 17 00:01:05,037 --> 00:01:07,512 Being cupped, rather than flat, 18 00:01:07,512 --> 00:01:12,035 enables it to better sense the direction of the incoming light. 19 00:01:12,035 --> 00:01:13,768 Among its other uses, 20 00:01:13,768 --> 00:01:19,488 this ability allows an organism to seek out shade and hide from predators. 21 00:01:19,488 --> 00:01:20,602 Over the millenia, 22 00:01:20,602 --> 00:01:23,429 as such light cups grew deeper in some organisms, 23 00:01:23,429 --> 00:01:26,453 the opening at the front grew smaller. 24 00:01:26,453 --> 00:01:31,187 The result was a pinhole effect, which increased resolution dramatically, 25 00:01:31,187 --> 00:01:36,464 reducing distortion by only allowing a thin beam of light into the eye. 26 00:01:36,464 --> 00:01:39,083 The nautilus, an ancestor of the octopus, 27 00:01:39,083 --> 00:01:45,148 uses this pinhole eye for improved resolution and directional sensing. 28 00:01:45,148 --> 00:01:48,559 Although the pinhole eye allows for simple images, 29 00:01:48,559 --> 00:01:52,487 the key step towards the eye as we know it is a lens. 30 00:01:52,487 --> 00:01:54,109 This is thought to have evolved 31 00:01:54,109 --> 00:01:58,556 through transparent cells covering the opening to prevent infection, 32 00:01:58,556 --> 00:02:01,617 allowing the inside of the eye to fill with fluid 33 00:02:01,617 --> 00:02:05,235 that optimizes light sensitivity and processing. 34 00:02:05,235 --> 00:02:07,435 Crystalline proteins forming at the surface 35 00:02:07,435 --> 00:02:09,905 created a structure that proved useful 36 00:02:09,905 --> 00:02:13,135 in focusing light at a single point on the retina. 37 00:02:13,135 --> 00:02:17,480 It is this lens that is the key to the eye's adability, 38 00:02:17,480 --> 00:02:21,789 changing its curvature to adapt to near and far vision. 39 00:02:21,789 --> 00:02:24,681 This structure of the pinhole camera with a lens 40 00:02:24,681 --> 00:02:29,784 served as the basis for what would eventually evolve into the human eye. 41 00:02:29,784 --> 00:02:33,193 Further refinements would include a colored ring, called the iris, 42 00:02:33,193 --> 00:02:36,384 that controls the amount of light entering the eye, 43 00:02:36,384 --> 00:02:41,409 a tough white outer layer known as the sclera to maintain its structure, 44 00:02:41,409 --> 00:02:45,469 and tear glands that secrete a protective film. 45 00:02:45,469 --> 00:02:49,477 But equally important was the accompanying evolution of the brain, 46 00:02:49,477 --> 00:02:51,501 with its expansion of the visual cortex 47 00:02:51,501 --> 00:02:56,157 to process the sharper and more colorful images it was receiving. 48 00:02:56,157 --> 00:03:00,242 We now know that far from being an ideal masterpiece of design, 49 00:03:00,242 --> 00:03:04,342 our eye bares traces of its step by step evolution. 50 00:03:04,342 --> 00:03:07,561 For example, the human retina is inverted, 51 00:03:07,561 --> 00:03:11,249 with light detecting cells facing away from the eye opening. 52 00:03:11,249 --> 00:03:12,904 This results in a blind spot, 53 00:03:12,904 --> 00:03:15,626 where the optic nerve must pierce the retina 54 00:03:15,626 --> 00:03:18,382 to reach the photosensitive layer in the back. 55 00:03:18,382 --> 00:03:21,528 The similar looking eyes of cephalopods, 56 00:03:21,528 --> 00:03:23,187 which evolved independently, 57 00:03:23,187 --> 00:03:27,970 have a front facing retina, allowing them to see without a blind spot. 58 00:03:27,970 --> 00:03:30,794 Other creatures eyes display different adaptations. 59 00:03:30,794 --> 00:03:33,732 Anableps, the so called four-eyed fish, 60 00:03:33,732 --> 00:03:38,802 have eyes divided in two sections for looking above and under water, 61 00:03:38,802 --> 00:03:42,258 perfect for spotting both predators and prey. 62 00:03:42,258 --> 00:03:47,465 Cats, classically nighttime hunters, have evolved with a reflective layer 63 00:03:47,465 --> 00:03:51,185 maximizing the amount of light the eye can detect, 64 00:03:51,185 --> 00:03:55,715 granting them excellent night vision, as well as their signature glow. 65 00:03:55,715 --> 00:04:00,468 These are just a few examples of the huge diversity of eyes in the animal kingdom. 66 00:04:00,468 --> 00:04:04,869 So if you could design an eye, would you do it any differently? 67 00:04:04,869 --> 00:04:07,632 This question isn't as strange as it might sound. 68 00:04:07,632 --> 00:04:11,285 Today, doctors and scientists are looking at different eye structures 69 00:04:11,285 --> 00:04:15,662 to help design biomechanical implants for the vision impaired. 70 00:04:15,662 --> 00:04:18,279 And in the not so distant future, 71 00:04:18,279 --> 00:04:22,200 the machines built with the precision and flexibilty of the human eye 72 00:04:22,200 --> 00:04:26,283 may even enable it to surpass its own evolution.