0:04:25.331,0:04:27.050
(Students' overlapping voices)

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(Clapping and singing)

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(Cheering)

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These are worms.

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Not the kind of worms[br]you find crawling in the dirt.

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These are parasitic roundworms.

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They live inside[br]a human being's intestines.

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Each of these worms[br]can grow up to 12 inches long,

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and there are 200 of them[br]in this jar for a reason,

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because that is the number[br]you might typically find

0:00:16.927,0:00:19.371
in the belly of a single infected child.

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Worm infections have been around[br]for thousands of years.

0:00:22.079,0:00:24.079
They have influenced the outcomes of wars,

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and they have long stymied human health.

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Roundworm, hookworm,

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whipworm, schistosomiasis:

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infections from these species[br]cause pain and discomfort.

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They steal nutrients and zap energy.

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They stunt both physical[br]and cognitive growth.

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In most cases, these worms[br]may not be fatal,

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but paradoxically,[br]that's part of the problem.

0:00:42.398,0:00:43.938
It means that many countries

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simply have not been able[br]to prioritize their treatment.

0:00:46.718,0:00:48.335
There's a social cost to that:

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children without access[br]to deworming treatments

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have lower rates of school attendance.

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Adults who grow up[br]without deworming medicine

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are less productive[br]and have lower lifelong earnings.

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What intestinal worms do, really,

0:00:59.738,0:01:01.165
is limit potential.

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Currently, there are 1.7 billion people[br]in the world still at risk for worms.

0:01:05.432,0:01:07.878
Six hundred million of them are in Africa.

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For every dollar invested[br]in worm control and prevention,

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African countries see up to 42 dollars[br]return in economic benefits.

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The good news is that deworming[br]treatment is extremely easy.

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One to three pills[br]given once or twice a year

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is enough to take a child[br]from 200 worms to zero

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and to protect them[br]from infection going forward.

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In communities where[br]there's a high prevalence of worms,

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treatment can be done right at school.

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This process is extremely simple and fast.

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In Ethiopia, for example,[br]this is done for 20 million children

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in a matter of weeks.

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The world has come a long way

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on getting deworming medicines[br]to the people who need them,

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and African governments[br]want to gain more traction.

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It's now time to match their ambition.

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The END Fund will work with governments

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to create a plan that drastically reduces[br]the burden of disease caused by worms.

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They’ll work together to ensure[br]prevention and treatment programs

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can serve everyone.

0:01:58.921,0:02:01.100
The END Fund has an audacious idea:

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they believe we are the generation to end[br]sickness from worm infections forever.

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The key is not simply to build[br]new programs from scratch,

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but to amplify the efforts of the programs[br]that are already taking shape.

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By examining the problem[br]of how worms transmit disease,

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the END Fund has identified five key areas[br]where they can drive improvement.

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Number one: lower the cost of treatment.

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Many pharmaceutical companies[br]offer deworming medicines for free,

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so the END Fund[br]works with the right partners

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to coordinate their delivery.

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They will continue[br]to secure drug donations

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for additional at-risk populations.

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They can now do it for less[br]than 25 cents per child per year.

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Number two: focus on prevention.

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The END Fund calls in the right partners[br]to educate communities

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on sanitation and hygiene

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in order to change behaviors[br]around things like hand-washing

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and latrine use,

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ensuring people[br]are not continually reinfected.

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Number three: invest in innovation.

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The END Fund has contributed to deworming

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by introducing innovative techniques[br]that effectively target and treat people.

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They will test new delivery methods,

0:03:03.839,0:03:06.031
target the environments[br]where parasites thrive

0:03:06.055,0:03:07.766
and influence behavior change.

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Number four: monitor and evaluate.

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The END Fund collects detailed data[br]on all programs on a regular basis

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to help them get better[br]and better over time.

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Number five: increase local ownership.

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At all stages of the process,

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the END Fund works with government[br]and local stakeholders

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to encourage cofinancing commitments[br]that support deworming efforts.

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They also worked[br]with African philanthropists

0:03:30.784,0:03:33.631
and corporate leaders[br]to partner on these efforts.

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There's an incredible opportunity[br]to work together to create a new system

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for disease elimination[br]for the next decade and beyond.

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Part of the money the END Fund needs

0:03:42.426,0:03:45.027
will go directly toward delivering[br]deworming treatments

0:03:45.051,0:03:46.449
to communities that need it

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and part will go towards facilitating[br]the handover of programs

0:03:49.918,0:03:51.219
to local ownership.

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Together, these efforts will create[br]prevention and treatment programs

0:03:54.728,0:03:57.314
that are sustainable far into the future.

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If this plan gets fully funded[br]for the next six years,

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tens of millions of people[br]will receive deworming treatment.

0:04:04.883,0:04:08.605
With that, countries will be interrupting[br]the cycle of disease transmission

0:04:08.629,0:04:09.800
at all levels,

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and most importantly, people[br]will experience significant improvements

0:04:13.701,0:04:16.652
in their mental, physical[br]and social health.

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Just imagine the potential[br]that will be gained

0:04:19.218,0:04:21.637
when people can stop worrying about these

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and can put their energy[br]into things like these.