WEBVTT 99:59:59.999 --> 99:59:59.999 Can we, as adults, grow new nerve cells? 99:59:59.999 --> 99:59:59.999 There's still some confusion about that question, 99:59:59.999 --> 99:59:59.999 as this is a fairly new field of research. 99:59:59.999 --> 99:59:59.999 For example, I was talking to one of my colleagues, Robert -- 99:59:59.999 --> 99:59:59.999 who is an oncologist -- 99:59:59.999 --> 99:59:59.999 and he was telling me, 99:59:59.999 --> 99:59:59.999 "Sandrine, this is puzzling, 99:59:59.999 --> 99:59:59.999 some of my patients that have been told they are cured of their cancer, 99:59:59.999 --> 99:59:59.999 still develop symptoms of depression." 99:59:59.999 --> 99:59:59.999 And I responded to him, 99:59:59.999 --> 99:59:59.999 "Well, from my point of view that makes sense. 99:59:59.999 --> 99:59:59.999 The drug you give to your patients that stops the cancer cells multiplying, 99:59:59.999 --> 99:59:59.999 also stops the newborn neurons being generated in their brain." 99:59:59.999 --> 99:59:59.999 And then Robert looked at me like I was crazy and said, 99:59:59.999 --> 99:59:59.999 "But Sandrine, these are adult patients, adults do not grow new nerve cells." 99:59:59.999 --> 99:59:59.999 And much to his surprise, I said, "Well actually, we do." 99:59:59.999 --> 99:59:59.999 And this is a phenomenon that we call Neurogenesis. 99:59:59.999 --> 99:59:59.999 [Neurogenesis] 99:59:59.999 --> 99:59:59.999 Now, Robert is not a neuroscientist, so when he went to medical school, 99:59:59.999 --> 99:59:59.999 so when he went to medical school he was not taught what we know now -- 99:59:59.999 --> 99:59:59.999 that the adult brain can generate new nerve cells. 99:59:59.999 --> 99:59:59.999 So, Robert, you know, being a good doctor that he is, 99:59:59.999 --> 99:59:59.999 wanted to come to my lab to understand the topic a little bit better. 99:59:59.999 --> 99:59:59.999 And I took him for a tour 99:59:59.999 --> 99:59:59.999 of one the of most exciting parts of the brain, 99:59:59.999 --> 99:59:59.999 when it comes to Neurogenesis -- 99:59:59.999 --> 99:59:59.999 and this is the Hippocampus. 99:59:59.999 --> 99:59:59.999 So this is this gray structure in the center of the brain. 99:59:59.999 --> 99:59:59.999 And what we've known for what seems like already for very long, 99:59:59.999 --> 99:59:59.999 is that this is important for learning, memory, mood and emotion. 99:59:59.999 --> 99:59:59.999 However, what we have learned more recently, 99:59:59.999 --> 99:59:59.999 is that this is one of the unique structures of the adult brain 99:59:59.999 --> 99:59:59.999 where new neurons can be generated. 99:59:59.999 --> 99:59:59.999 And if we slide through the Hippocampus 99:59:59.999 --> 99:59:59.999 and zoom in, 99:59:59.999 --> 99:59:59.999 what you actually see here in blue 99:59:59.999 --> 99:59:59.999 is a newborn neuron in an adult mouse brain. 99:59:59.999 --> 99:59:59.999 So when it comes to the human brain, 99:59:59.999 --> 99:59:59.999 my colleague Dr. Jonas Frisén from the Karolinska Institute, 99:59:59.999 --> 99:59:59.999 has estimated that we produce 99:59:59.999 --> 99:59:59.999 700 new neurons per day in the Hippocampus. 99:59:59.999 --> 99:59:59.999 So you might think this is not much according the to billions of neurons we have, 99:59:59.999 --> 99:59:59.999 according to the billions of neurons we have, 99:59:59.999 --> 99:59:59.999 but by the time we will turn 50