0:00:01.080,0:00:05.376 What if you could make[br]your sleep more efficient? 0:00:05.400,0:00:07.136 As a sleep scientist, 0:00:07.160,0:00:10.056 this is the question[br]that has captivated me 0:00:10.080,0:00:11.640 for the past 10 years. 0:00:12.360,0:00:16.936 Because while the lightbulb[br]and technology have brought about a world 0:00:16.960,0:00:20.416 of 24-hour work and productivity, 0:00:20.440,0:00:22.096 it has come at the cost 0:00:22.120,0:00:25.416 of our naturally occurring[br]circadian rhythm 0:00:25.440,0:00:27.640 and our body's need for sleep. 0:00:28.520,0:00:32.456 The circadian rhythm dictates[br]our energy level throughout the day, 0:00:32.479,0:00:37.336 and only recently we've been conducting[br]a global experiment on this rhythm, 0:00:37.360,0:00:39.416 which is putting our sleep health 0:00:39.440,0:00:42.840 and ultimately[br]our life quality in jeopardy. 0:00:44.240,0:00:45.496 Because of this, 0:00:45.520,0:00:47.656 we aren't getting the sleep we need, 0:00:47.680,0:00:51.416 with the average American[br]sleeping a whole hour less 0:00:51.440,0:00:53.936 than they did in the 1940s. 0:00:53.960,0:00:55.216 For some reason, 0:00:55.240,0:00:57.496 we decided to wear it as a badge of honor 0:00:57.520,0:00:59.760 that we can get by on not enough sleep. 0:01:00.400,0:01:04.120 This all adds up to a real health crisis. 0:01:04.879,0:01:08.536 Most of us know that poor sleep[br]is linked to diseases 0:01:08.560,0:01:11.296 like Alzheimer's, cardiovascular disease, 0:01:11.320,0:01:13.360 stroke and diabetes. 0:01:13.880,0:01:17.696 And if you go untreated[br]with a sleep disorder like sleep apnea, 0:01:17.720,0:01:20.480 you're more likely[br]to get many of these illnesses. 0:01:21.080,0:01:25.480 But did you know about sleep's impact[br]on your mental states? 0:01:26.360,0:01:30.736 Poor sleep makes us[br]make risky, rash decisions 0:01:30.760,0:01:33.720 and is a drain[br]on our capacity for empathy. 0:01:34.720,0:01:40.136 When sleep deprivation literally makes us[br]more sensitive to our own pain, 0:01:40.160,0:01:44.176 it's not so surprising that we have[br]a hard time relating to others 0:01:44.200,0:01:47.416 and just generally[br]being a good and healthy person 0:01:47.440,0:01:48.920 when we're sleep-deprived. 0:01:49.640,0:01:52.296 Scientists are now starting to understand 0:01:52.320,0:01:54.496 how not only the quantity 0:01:54.520,0:01:59.320 but also the quality of sleep[br]impacts our health and well-being. 0:02:00.360,0:02:02.176 My research focuses 0:02:02.200,0:02:07.216 on what many scientists believe[br]is the most regenerative stage of sleep: 0:02:07.240,0:02:08.440 deep sleep. 0:02:08.919,0:02:11.256 We now know that generally speaking, 0:02:11.280,0:02:13.896 there are three stages of sleep: 0:02:13.920,0:02:15.256 light sleep, 0:02:15.280,0:02:17.296 rapid eye movement or REM 0:02:17.320,0:02:18.520 and deep sleep. 0:02:19.080,0:02:24.760 We measure these stages by connecting[br]electrodes to the scalp, chin and chest. 0:02:25.600,0:02:27.056 In light sleep and REM, 0:02:27.080,0:02:31.320 our brain waves are very similar[br]to our brain waves in waking life. 0:02:31.720,0:02:35.816 But our brain waves in deep sleep[br]have these long-burst brain waves 0:02:35.840,0:02:38.976 that are very different[br]from our waking life brain waves. 0:02:39.000,0:02:43.400 These long-burst brain waves[br]are called delta waves. 0:02:44.600,0:02:47.056 When we don't get the deep sleep we need, 0:02:47.080,0:02:49.256 it inhibits our ability to learn 0:02:49.280,0:02:52.080 and for our cells and bodies to recover. 0:02:52.920,0:02:56.096 Deep sleep is how we convert[br]all those interactions 0:02:56.120,0:02:57.816 that we make during the day 0:02:57.840,0:03:00.560 into our long-term memory[br]and personalities. 0:03:01.200,0:03:02.456 As we get older, 0:03:02.480,0:03:05.976 we're more likely to lose[br]these regenerative delta waves. 0:03:06.000,0:03:08.816 So in way, deep sleep and delta waves 0:03:08.840,0:03:12.480 are actually a marker[br]for biological youth. 0:03:13.680,0:03:17.216 So naturally, I wanted to get[br]more deep sleep for myself 0:03:17.240,0:03:22.936 and I literally tried almost every gadget,[br]gizmo, device and hack out there -- 0:03:22.960,0:03:24.896 consumer-grade, clinical-grade, 0:03:24.920,0:03:26.120 what have you. 0:03:26.720,0:03:30.536 I learned a lot, and I found[br]I really do need, like most people, 0:03:30.560,0:03:32.216 eight hours of sleep. 0:03:32.240,0:03:35.296 I even shifted my circadian component 0:03:35.320,0:03:39.016 by changing my meals,[br]exercise and light exposure, 0:03:39.040,0:03:43.296 but I still couldn't find a way[br]to get a deeper night of sleep ... 0:03:43.320,0:03:46.376 that is until I met[br]Dr. Dmitry Gerashchenko 0:03:46.400,0:03:48.696 from Harvard Medical School. 0:03:48.720,0:03:51.896 Dmitry told me about[br]a new finding in the literature, 0:03:51.920,0:03:56.336 where a lab out of Germany showed[br]that if you could play certain sounds 0:03:56.360,0:03:58.896 at the right time in people's sleep, 0:03:58.920,0:04:02.360 you could actually make sleep[br]deeper and more efficient. 0:04:03.080,0:04:05.736 And what's more, is that this lab showed 0:04:05.760,0:04:09.256 that you actually could improve[br]next-day memory performance 0:04:09.280,0:04:10.480 with this sound. 0:04:11.080,0:04:12.456 Dmitry and I teamed up, 0:04:12.480,0:04:15.976 and we began working on a way[br]to build this technology. 0:04:16.000,0:04:19.079 With our research lab[br]collaborators at Penn State, 0:04:20.440,0:04:23.856 we designed experiments[br]in order to validate our system. 0:04:23.880,0:04:27.496 And we've since received grant funding[br]from the National Science Foundation 0:04:27.520,0:04:29.536 and the National Institute of Health 0:04:29.560,0:04:32.480 to develop this deep-sleep[br]stimulating technology. 0:04:33.480,0:04:35.056 Here's how it works. 0:04:35.080,0:04:36.336 People came into the lab 0:04:36.360,0:04:38.736 and we hooked them up[br]to a number of devices, 0:04:38.760,0:04:40.536 two of which I have on right here -- 0:04:40.560,0:04:41.816 not a fashion statement. 0:04:41.840,0:04:43.360 (Laughter) 0:04:44.200,0:04:47.016 When we detected[br]that people were in deep sleep, 0:04:47.040,0:04:49.696 we played the deep-sleep[br]stimulating sounds 0:04:49.720,0:04:52.376 that were shown[br]to make them have deeper sleep. 0:04:52.400,0:04:54.680 I'm going to demo this sound[br]for you right now. 0:04:56.280,0:05:00.040 (Repeating sound waves) 0:05:04.560,0:05:05.816 Pretty weird, right? 0:05:05.840,0:05:07.576 (Laughter) 0:05:07.600,0:05:13.056 So that sound is actually at the same[br]burst frequency as your brain waves 0:05:13.080,0:05:15.416 when your brain is in deep sleep. 0:05:15.440,0:05:18.696 That sound pattern[br]actually primes your mind 0:05:18.720,0:05:21.360 to have more of these[br]regenerative delta waves. 0:05:22.160,0:05:25.016 When we asked participants[br]the next day about the sounds, 0:05:25.040,0:05:27.936 they were completely unaware[br]that we played the sounds, 0:05:27.960,0:05:31.840 yet their brains responded[br]with more of these delta waves. 0:05:32.280,0:05:36.176 Here's an image of someone's brain waves[br]from the study that we conducted. 0:05:36.200,0:05:37.896 See the bottom panel? 0:05:37.920,0:05:41.416 This shows the sound being played[br]at that burst frequency. 0:05:41.440,0:05:44.536 Now look at the brain waves[br]in the upper part of the graph. 0:05:44.560,0:05:46.496 You can see from the graph 0:05:46.520,0:05:51.000 that the sound is actually producing[br]more of these regenerative delta waves. 0:05:52.120,0:05:54.936 We learned that we could[br]accurately track sleep 0:05:54.960,0:05:57.656 without hooking people up to electrodes 0:05:57.680,0:06:00.776 and make people sleep deeper. 0:06:00.800,0:06:02.216 We're continuing to develop 0:06:02.240,0:06:05.656 the right sound environment[br]and sleep habitat 0:06:05.680,0:06:08.000 to improve people's sleep health. 0:06:08.640,0:06:12.256 Our sleep isn't[br]as regenerative as it could be, 0:06:12.280,0:06:14.096 but maybe one day soon, 0:06:14.120,0:06:16.536 we could wear a small device 0:06:16.560,0:06:18.640 and get more out of our sleep. 0:06:19.040,0:06:20.256 Thank you. 0:06:20.280,0:06:24.040 (Applause)