9:59:59.000,9:59:59.000 0:00:00.450,0:00:02.550 In this video, I want to[br]cover several topics 0:00:02.550,0:00:03.650 that are all related. 0:00:03.650,0:00:05.850 And on some level, they're[br]really simple, but on a whole 0:00:05.850,0:00:07.883 other level, they tend to[br]confuse people a lot. 0:00:07.883,0:00:10.110 So hopefully we can[br]make some headway. 0:00:10.110,0:00:12.400 So a good place to start-- let's[br]just imagine that I have 0:00:12.400,0:00:15.460 some type of container here. 0:00:15.460,0:00:18.130 Let's say that's my container[br]and inside of that container, 0:00:18.130,0:00:21.430 I have a bunch of[br]water molecules. 0:00:21.430,0:00:24.070 It's just got a bunch[br]of water molecules. 0:00:24.070,0:00:25.550 They're all rubbing against[br]each other. 0:00:25.550,0:00:27.920 It's in its liquid form,[br]this is liquid water. 0:00:27.920,0:00:30.340 and inside of the water[br]molecules, I 0:00:30.340,0:00:33.050 have some sugar molecules. 0:00:33.050,0:00:35.790 Maybe I'll do sugar in[br]this pink color. 0:00:35.790,0:00:40.690 So I have a bunch of sugar[br]molecules right here. 0:00:40.690,0:00:43.040 I have many, many more water[br]molecules though. 0:00:43.040,0:00:44.290 I want to make that clear. 0:00:44.290,0:00:49.420 I have many, many more water molecules in this container that we are dealing with. 0:00:49.420,0:00:55.660 Now in this type of situation,[br]we call, we call the thing that there's 0:00:55.660,0:01:00.440 more of, the solvent. 0:01:00.440,0:01:03.350 So in this case, there's more[br]water molecules and you can 0:01:03.350,0:01:07.990 literally just view more as[br]the number of molecules. 0:01:07.990,0:01:10.010 I'm not going to go into a whole[br]discussion of moles and 0:01:10.010,0:01:13.140 all of that because you may or[br]may not have been exposed to 0:01:13.140,0:01:15.670 that yet, but just imagine[br]whatever there's more of, 0:01:15.670,0:01:17.740 that's what we're going[br]to call the solvent. 0:01:17.740,0:01:24.630 So in this case, water[br]is the solvent. 0:01:24.630,0:01:30.030 And whatever there is less of, so the more water is the solvent and in that case, that is the[br]in this case, that is the 0:01:30.030,0:01:32.730 sugar-- that is considered[br]the solute. 0:01:32.730,0:01:36.292 this is the solute, so the sugar. 0:01:36.292,0:01:37.640 It doesn't have to be sugar. 0:01:37.640,0:01:40.320 It could be any molecule that[br]there's less of, in the water, 0:01:40.320,0:01:41.570 in this case,sugar. 0:01:41.570,0:01:45.750 is the solute 0:01:45.750,0:01:49.620 And we say that the sugar has[br]been dissolved into the water. 0:01:49.620,0:02:03.500 sugar,has been dissolved, dissolved into, into the water 0:02:03.500,0:02:06.420 And this whole thing right here,[br]the combination of the 0:02:06.420,0:02:10.229 water and the sugar molecules,[br]we call a solution. 0:02:10.229,0:02:14.140 We call this whole[br]thing a solution. 0:02:14.140,0:02:16.870 And a solution has a solvent[br]and the solute. 0:02:16.870,0:02:18.160 The solvent is water. 0:02:18.160,0:02:21.110 That's the thing doing the[br]dissolving and the thing that 0:02:21.110,0:02:23.220 is dissolved is the sugar. 0:02:23.220,0:02:24.290 That's the solute. 0:02:24.290,0:02:27.950 Now all of this may or may not[br]be review for you, but I'm 0:02:27.950,0:02:32.870 doing it for a reason-- because[br]I want to talk about, I want to talk about 0:02:32.870,0:02:34.370 the idea of diffusion, diffusion 0:02:39.960,0:02:43.490 And the,the idea is actually[br]pretty straightforward. 0:02:43.490,0:02:46.790 If I have, let's say,let's same[br]the same container. 0:02:46.790,0:02:49.600 Let me do it in a slightly[br]different container here, just 0:02:49.600,0:02:50.640 to talk about diffusion. 0:02:50.640,0:02:52.180 We'll go back to water[br]and sugar-- 0:02:52.180,0:02:54.070 especially back to water. 0:02:54.070,0:02:58.570 Let's say we have a container[br]here and let's say it just has 0:02:58.570,0:03:00.830 a bunch of-- let's say it just[br]has some air particles in it. 0:03:00.830,0:03:03.560 It could be anything-- oxygen[br]or carbon dioxide. 0:03:03.560,0:03:07.880 So let me just draw a couple[br]of air molecules here. 0:03:07.880,0:03:11.060 So let's say that that is a[br]gaseous-- just for the sake of 0:03:11.060,0:03:12.590 argument-- gaseous oxygen. 0:03:12.590,0:03:14.900 So each of this is an O2--[br]each of those, right? 0:03:14.900,0:03:16.900 And let's say that this is the[br]current configuration, that 0:03:16.900,0:03:19.710 all of this is a vacuum here[br]and that there's some 0:03:19.710,0:03:20.220 temperatures. 0:03:20.220,0:03:22.490 So these water molecules,[br]they have some 0:03:22.490,0:03:25.280 type, some type of kinetic energy. 0:03:25.280,0:03:29.620 They're moving in some type of[br]random directions right there. 0:03:29.620,0:03:34.760 So my question is, what is going[br]to happen, what is goign to happen in this type 0:03:34.760,0:03:35.810 of container? 0:03:35.810,0:03:38.710 Well, any of these guys are[br]going to be randomly bumping 0:03:38.710,0:03:39.770 into each other. 0:03:39.770,0:03:43.030 They're more likely to bump into[br]things in this down-left 0:03:43.030,0:03:45.120 direction than they are in[br]the up-right direction. 0:03:45.120,0:03:47.970 So if this guy was happening[br]to go in this down-left 0:03:47.970,0:03:50.110 direction, he's going to bump[br]into something and then 0:03:50.110,0:03:52.070 ricochet into the up-right[br]direction. 0:03:52.070,0:03:53.480 But in the up-right[br]direction, there's 0:03:53.480,0:03:55.040 nothing to bounce into. 0:03:55.040,0:03:57.990 So in general, everything is[br]moving in random directions, 0:03:57.990,0:04:00.250 but you're more likely[br]to be able to move in 0:04:00.250,0:04:01.000 the rightward direction. 0:04:01.000,0:04:02.500 When you go to the left, you're[br]more likely to bump 0:04:02.500,0:04:04.130 into each other, into something. 0:04:04.130,0:04:06.090 So it's almost common sense. 0:04:06.090,0:04:09.550 Over time, if you just let this[br]system come to some type 0:04:09.550,0:04:11.580 of equilibrium-- I'm not[br]going to go into detail 0:04:11.580,0:04:12.340 on what that means. 0:04:12.340,0:04:14.340 You can watch the thermodynamics[br]videos if you'd 0:04:14.340,0:04:15.470 like to see that. 0:04:15.470,0:04:18.000 You'll eventually see the[br]container will look 0:04:18.000,0:04:19.140 something like this. 0:04:19.140,0:04:20.200 I can't guarantee it. 0:04:20.200,0:04:22.500 There's some probability it[br]would actually stay like this, 0:04:22.500,0:04:25.920 but very likely that those five[br]particles are going to 0:04:25.920,0:04:27.970 get relatively spread out. 0:04:27.970,0:04:32.790 This is diffusion and so it's[br]really just the spreading of 0:04:32.790,0:04:36.940 particles or molecules from[br]high concentration to low 0:04:36.940,0:04:39.140 concentration areas, right? 0:04:39.140,0:04:41.420 In this case, the molecules are[br]going to spread in that 0:04:41.420,0:04:43.780 direction from a high[br]concentration to a low 0:04:43.780,0:04:45.130 concentration area. 0:04:45.130,0:04:47.920 Now you're saying, Sal,[br]what is concentration? 0:04:47.920,0:04:51.060 And there's many ways to measure[br]concentration and you 0:04:51.060,0:04:54.120 can go into molarity and[br]molality and all of that. 0:04:54.120,0:04:57.830 But the very simple idea is, how[br]much of that particle do 0:04:57.830,0:04:59.900 you have per unit space? 0:04:59.900,0:05:02.780 So here, you have a lot of those[br]particles per unit space 0:05:02.780,0:05:04.550 and here you have very[br]few of those 0:05:04.550,0:05:05.850 particles per unit space. 0:05:05.850,0:05:09.230 So this is a high concentration[br]and that's a low 0:05:09.230,0:05:09.970 concentration. 0:05:09.970,0:05:12.740 So you could imagine other[br]experiments like this. 0:05:12.740,0:05:17.000 You could imagine a solution[br]like-- let's do 0:05:17.000,0:05:18.250 something like this. 0:05:18.250,0:05:21.570 let me make 0:05:21.570,0:05:22.820 Let's say I have[br]two containers. 0:05:22.820,0:05:25.440 let's see two container. 0:05:25.440,0:05:27.230 Let's go back to the[br]solution situation. 0:05:27.230,0:05:29.720 This was a gas, but I started[br]off with that example so let's 0:05:29.720,0:05:31.432 stay with that example. 0:05:31.432,0:05:35.530 So let's say that I have a door[br]right there that's larger 0:05:35.530,0:05:38.370 than either the water or[br]the sugar molecules. 0:05:38.370,0:05:41.305 On either side, I have a bunch[br]of water molecules. 0:05:41.305,0:05:52.020 I have a bunch of water molecules on either side, just like that on either side 0:05:52.020,0:05:53.300 So I have a lot of[br]water molecules. 0:05:53.300,0:05:55.650 So if I just had water molecules[br]here-- they're all 0:05:55.650,0:05:58.690 bouncing around in random[br]directions-- and so the odds 0:05:58.690,0:06:01.890 of a water molecule going this[br]way, equivalent to what odds of a 0:06:01.890,0:06:04.590 water molecule going that way,[br]assuming that both sides have 0:06:04.590,0:06:06.570 the same level of water[br]molecule, otherwise the 0:06:06.570,0:06:07.510 pressures would be different. 0:06:07.510,0:06:10.070 But let's say, you know that the top[br]of this is the same 0:06:10.070,0:06:11.170 as the top of this. 0:06:11.170,0:06:12.730 So there's no more pressure[br]going in one 0:06:12.730,0:06:13.790 direction or another. 0:06:13.790,0:06:17.240 So you know if,it for whatever reason, a[br]bunch of more water molecules 0:06:17.240,0:06:18.772 were going in the rightward[br]direction, then all of a 0:06:18.772,0:06:20.760 sudden this would fill up with[br]more water and we know that 0:06:20.760,0:06:22.620 that isn't likely to occur. 0:06:22.620,0:06:28.200 So this is,you know, this is just a solution, with or , this is just two containers of waters[br]of water. 0:06:28.200,0:06:30.340 Now let's put some[br]solute in it. 0:06:30.340,0:06:33.230 Let's dissolve some solute in it[br]and let's say we do all the 0:06:33.230,0:06:35.630 dissolving on the[br]left-hand side. 0:06:35.630,0:06:40.620 So we put some sugar molecules[br]on the left-hand side. 0:06:40.620,0:06:42.910 And these are small enough to[br]fit through this little pipe. 0:06:42.910,0:06:44.280 right, that's just one assumption[br]that I'm making. 0:06:44.280,0:06:45.120 So what's going to happen? 0:06:45.120,0:06:47.710 All of these things have some[br]type of kinetic energy. 0:06:47.710,0:06:52.630 They're all bouncing , they're all bouncing around. 0:06:52.630,0:06:56.250 Well, over time,you know, the water's[br]going back and forth. 0:06:56.250,0:06:57.600 This water molecule[br]might go that way. 0:06:57.600,0:07:00.040 That water molecule might go[br]that way, but they net out each 0:07:00.040,0:07:03.810 other out, but over time one of[br]these big sugar molecules 0:07:03.810,0:07:06.520 will be going in just the[br]right direction to go 0:07:06.520,0:07:08.470 through--maybe you know maybe this guy's,[br]instead of going that 0:07:08.470,0:07:10.380 direction, he starts off going[br]in that direction. 0:07:10.380,0:07:15.630 He goes just through this,throught this,uhm throught this tunnel[br]connecting this two 0:07:15.630,0:07:18.050 containers and he'll end[br]up there, right? 0:07:18.050,0:07:20.320 And this guy will still[br]be bouncing around. 0:07:20.320,0:07:23.570 There's some probability he goes[br]back, but there's still 0:07:23.570,0:07:25.420 more particles,more sugar particles[br]here than there. 0:07:25.420,0:07:31.350 So there's still more[br]probability that one of, so these 0:07:31.350,0:07:33.350 guys will go to that side[br]than one of these guys 0:07:33.350,0:07:34.340 will go to that side, that one of these guys will go to that side, 0:07:34.340,0:07:36.980 So you can imagine if you're[br]doing this with gazillions of 0:07:36.980,0:07:40.650 particles-- I'm only doing it[br]with four-- over time, the 0:07:40.650,0:07:43.440 particles will have spread out[br]so that their concentrations 0:07:43.440,0:07:44.550 are roughly equal. 0:07:44.550,0:07:46.950 So that maybe you'll have[br]two here over time. 0:07:46.950,0:07:49.430 But if, but when you're only dealing[br]with three or four or five 0:07:49.430,0:07:51.380 particles, there's some[br]probability it doesn't happen, 0:07:51.380,0:07:53.240 but when you're doing it with a[br]gazillion and they're super 0:07:53.240,0:07:56.810 small, it's a very, very,[br]very high likelihood. 0:07:56.810,0:07:59.590 But anyway, this whole process--[br]we went from a 0:07:59.590,0:08:02.460 container of high concentration[br]to a container 0:08:02.460,0:08:06.080 of low concentration and the[br]particles would have spread 0:08:06.080,0:08:08.530 from the low concentration[br]container to the high 0:08:08.530,0:08:09.590 concentration container. 0:08:09.590,0:08:11.130 So they diffused. 0:08:11.130,0:08:12.820 This is diffusion. 0:08:12.820,0:08:16.170 This is diffusion 0:08:16.170,0:08:18.880 And just so that we learn some[br]other words that tend to be 0:08:18.880,0:08:21.800 used with the idea of[br]diffusion-- when we started 0:08:21.800,0:08:24.260 off, this had a higher[br]concentration. 0:08:24.260,0:08:26.715 The left-hand side container[br]had higher concentration. 0:08:26.715,0:08:33.110 Higher concentration, higher concentration 0:08:33.110,0:08:34.130 It's all relative, right? 0:08:34.130,0:08:37.480 It's higher than this guy,higher concentration 0:08:37.480,0:08:39.505 And this right here had[br]a lower concentration. 0:08:39.505,0:08:42.799 Lower concentrarion 0:08:42.799,0:08:44.450 And there are words[br]for these things. 0:08:44.450,0:08:47.650 This solution with a high[br]concentration is called a 0:08:47.650,0:08:50.330 hypertonic solution. 0:08:50.330,0:08:51.730 Let me write that in yellow. 0:08:51.730,0:08:58.330 Hyoer, Hypertonic solution 0:08:58.330,0:09:01.120 Hyper, in general, meaning[br]having a lot of something, 0:09:01.120,0:09:02.620 having too much of something. 0:09:02.620,0:09:05.925 And this lower concentration[br]is hypo, hypotonic 0:09:05.925,0:09:13.720 Hypotonic solution,lower concentration 0:09:13.720,0:09:16.660 You might have heard maybe one[br]of your relatives, if they 0:09:16.660,0:09:20.730 haven't had a meal in awhile[br]say, I'm hypoglycemic. 0:09:20.730,0:09:22.230 That means that they have[br]not-- they're feeling 0:09:22.230,0:09:22.910 lightheaded. 0:09:22.910,0:09:24.800 There's not enough sugar in[br]their bloodstream and they 0:09:24.800,0:09:26.730 want to pass out so[br]they want a meal. 0:09:26.730,0:09:29.930 If you just had a candy bar,[br]maybe you're hyperglycemic-- 0:09:29.930,0:09:32.930 or maybe you're just[br]hyper in general. 0:09:32.930,0:09:35.580 But, so, you know, so these are just good[br]prefixes to know, but 0:09:35.580,0:09:38.650 hypertonic-- you have[br]a lot of the solute. 0:09:38.650,0:09:40.510 You have a high concentration. 0:09:40.510,0:09:44.500 And then in hypotonic, not too[br]much of the solute so you have 0:09:44.500,0:09:46.010 a low concentration. 0:09:46.010,0:09:47.130 These are good words to know. 0:09:47.130,0:09:51.220 So in general, diffusion-- if[br]there's no barriers to the 0:09:51.220,0:09:54.790 diffusion like we had here, you[br]will have the solute go 0:09:54.790,0:09:58.820 from a high concentration or[br]hypertonic solution if they 0:09:58.820,0:10:03.490 can travel to a hypotonic[br]solution, to a hypo, where the 0:10:03.490,0:10:05.520 concentration is lower. 0:10:05.520,0:10:08.480 Now let's do an interesting[br]experiment here. 0:10:08.480,0:10:10.930 We've talked about diffusion and[br]so far we've been talking 0:10:10.930,0:10:14.530 about the diffusion of[br]the solute, right? 0:10:14.530,0:10:17.770 And in general-- and this is not[br]always the case-- if you 0:10:17.770,0:10:19.780 want to be as general as[br]possible, the solute is 0:10:19.780,0:10:22.400 whatever you have less of,[br]the solvent is whatever 0:10:22.400,0:10:23.510 you have more of. 0:10:23.510,0:10:26.600 And the most common solvent[br]tends to be water, but it 0:10:26.600,0:10:27.520 doesn't have to be water. 0:10:27.520,0:10:28.870 It could be some type[br]of alcohol. 0:10:28.870,0:10:31.390 It could be a...you, know it could be mercury. 0:10:31.390,0:10:34.880 It could be a whole set of[br]molecules, but water in most 0:10:34.880,0:10:38.130 biological or chemical systems[br]tends to be the 0:10:38.130,0:10:39.460 most typical solvent. 0:10:39.460,0:10:41.920 It's what other things[br]are dissolved into. 0:10:41.920,0:10:46.380 But what happens if we have a[br]tunnel where the solute is too 0:10:46.380,0:10:51.060 big to travel, but water is[br]small enough to travel? 0:10:51.060,0:10:55.370 Let's think about[br]that situation, let's think about the situation 0:10:55.370,0:10:57.090 In order to think about it,[br]I'm going to do something 0:10:57.090,0:10:58.830 interesting. 0:10:58.830,0:11:02.670 Let's say we have a[br]container here,let's say 0:11:02.670,0:11:03.950 Actually, I won't even[br]draw a container. 0:11:03.950,0:11:07.190 Let's just say we have an[br]outside environment that has a 0:11:07.190,0:11:09.260 bunch of water. 0:11:09.260,0:11:12.630 This is the outside environment[br]and then you have 0:11:12.630,0:11:13.880 some type of membrane. 0:11:13.880,0:11:19.400 you have some type of membrane here, that's a membrane 0:11:19.400,0:11:22.040 Water can go in and out[br]of this membrane. 0:11:22.040,0:11:23.190 So it's semi-permeable. 0:11:23.190,0:11:26.520 Well, it's permeable to water,[br]but the solute cannot go 0:11:26.520,0:11:27.110 through the membrane. 0:11:27.110,0:11:28.680 So let's say that the[br]solute is sugar. 0:11:28.680,0:11:33.060 So we have water on[br]the outside and 0:11:33.060,0:11:36.126 also inside the membrane. 0:11:36.126,0:11:39.380 So these are little small[br]water molecules. 0:11:39.380,0:11:43.950 This is a membrane right here. 0:11:43.950,0:11:46.520 And let's say that we have some[br]sugar molecules again-- 0:11:46.520,0:11:47.560 I'm just picking on sugar. 0:11:47.560,0:11:48.760 It could have been anything. 0:11:48.760,0:11:51.050 So we have some sugar molecules[br]here that are just a 0:11:51.050,0:11:55.950 little bit bigger-- or they[br]could be a lot bigger. 0:11:55.950,0:11:57.750 Actually, they're a lot bigger[br]than water molecules. 0:11:57.750,0:11:59.700 You have a bunch of-- and I only[br]draw four, but you have a 0:11:59.700,0:12:01.210 gazillion of them, right? 0:12:01.210,0:12:03.470 You have that much more[br]water molecules. 0:12:03.470,0:12:05.325 I'm just trying to show you have[br]more water molecules than 0:12:05.325,0:12:06.290 sugar molecules. 0:12:06.290,0:12:07.645 And this membrane is[br]semi-permeable. 0:12:13.140,0:12:15.210 Permeable means it allows[br]things to pass. 0:12:15.210,0:12:18.070 Semi-permeables means it's[br]not completely permeable. 0:12:18.070,0:12:20.650 So semi-permeable-- in this[br]context, I'm saying I allow 0:12:20.650,0:12:22.440 water to pass through[br]the membrane. 0:12:22.440,0:12:28.850 So water can pass,[br]but sugar cannot. 0:12:28.850,0:12:30.100 Sugar is too large. 0:12:35.900,0:12:39.220 So if we were to zoom in on the[br]actual membrane itself-- 0:12:39.220,0:12:40.580 maybe the membrane[br]looks like this. 0:12:40.580,0:12:41.980 I'm going to zoom in[br]on this membrane. 0:12:44.530,0:12:48.620 So it has little holes in the[br]membrane, just like that. 0:12:48.620,0:12:51.270 And maybe the water molecules[br]are about that size. 0:12:51.270,0:12:53.820 So they can go through[br]those holes. 0:12:53.820,0:12:56.250 So the water molecules can go[br]back and forth through the 0:12:56.250,0:13:01.520 holes, but the sugar molecules[br]are about that big. 0:13:01.520,0:13:04.990 So they cannot go through[br]that hole. 0:13:04.990,0:13:07.280 They're too big for this opening[br]right here to go back 0:13:07.280,0:13:08.830 and forth between them. 0:13:08.830,0:13:12.680 Now what do you think is going[br]to happen in this situation? 0:13:12.680,0:13:14.330 So first of all, let's[br]use our terminology. 0:13:14.330,0:13:15.720 Remember, sugar is our solute. 0:13:15.720,0:13:17.120 Water is our solvent. 0:13:17.120,0:13:18.930 Semi-permeable membrane. 0:13:18.930,0:13:21.400 Which side of the membrane[br]has a higher or lower 0:13:21.400,0:13:24.330 concentration of solute? 0:13:24.330,0:13:25.690 Well, the inside does. 0:13:25.690,0:13:27.060 The inside is hypertonic. 0:13:32.370,0:13:33.540 The outside has a lower 0:13:33.540,0:13:34.850 concentration so it's hypotonic. 0:13:44.850,0:13:47.680 Now, if these openings were big[br]enough, based on what we 0:13:47.680,0:13:51.330 just talked about-- these guys[br]are bouncing around, water is 0:13:51.330,0:13:53.700 travelling in either direction,[br]and equal 0:13:53.700,0:13:56.520 probability or-- actually[br]I'm going to talk 0:13:56.520,0:13:58.360 about that in a second. 0:13:58.360,0:14:01.660 If everything was wide open, it[br]would be equal probability, 0:14:01.660,0:14:03.780 but if it was wide open, these[br]guys eventually would bounce 0:14:03.780,0:14:06.450 their ways over to this side and[br]you'd probably end up with 0:14:06.450,0:14:08.500 equal concentrations[br]eventually. 0:14:08.500,0:14:10.710 And so you would have your[br]traditional diffusion, where 0:14:10.710,0:14:13.130 high concentration[br]of solute to low 0:14:13.130,0:14:14.530 concentrations of solute. 0:14:14.530,0:14:17.350 But in this case, these[br]guys-- they can't 0:14:17.350,0:14:18.330 fit through the hole. 0:14:18.330,0:14:20.160 Only water can go[br]back and forth. 0:14:20.160,0:14:25.180 If these guys were not here,[br]water would have an equal 0:14:25.180,0:14:28.780 likelihood of going in this[br]direction as they would be 0:14:28.780,0:14:33.940 going in that direction, a[br]completely equal likelihood. 0:14:33.940,0:14:40.090 But because these guys are on[br]the right-hand side of-- or in 0:14:40.090,0:14:42.290 this case, on the inside[br]of our membrane. 0:14:42.290,0:14:47.000 This is our inside of our[br]membrane zoomed up-- it's less 0:14:47.000,0:14:50.440 likely because these guys[br]might be in the approach 0:14:50.440,0:14:55.230 position of the holes-- that's[br]slightly less likely for water 0:14:55.230,0:14:58.110 to be in the approach position[br]for the holes so it's actually 0:14:58.110,0:15:02.720 more probable that water could[br]enter than water exit. 0:15:02.720,0:15:04.180 And I want to make[br]that very clear. 0:15:04.180,0:15:07.150 If these sugar molecules were[br]not here, obviously it's 0:15:07.150,0:15:09.830 equally likely for water to[br]go in either direction. 0:15:09.830,0:15:12.730 Now that these sugar molecules[br]are there, these sugar 0:15:12.730,0:15:15.290 molecules might be on[br]the right-hand side. 0:15:15.290,0:15:18.200 They might be blocking-- I guess[br]the best way to think 0:15:18.200,0:15:20.430 about it is blocking the[br]approach to the hole. 0:15:20.430,0:15:22.060 They'll never be able to go[br]through the hole themselves 0:15:22.060,0:15:24.490 and might not even be blocking[br]the hole, but they're going in 0:15:24.490,0:15:25.720 some random direction. 0:15:25.720,0:15:29.580 So if a water molecule was[br]approaching-- it's all 0:15:29.580,0:15:31.360 probabilistic and we're dealing[br]with gazillions of 0:15:31.360,0:15:34.610 molecules-- it's that much more[br]likely to be blocked to 0:15:34.610,0:15:35.360 get outside. 0:15:35.360,0:15:37.620 But the water molecules from the[br]outside-- there's nothing 0:15:37.620,0:15:40.170 blocking them to get in so[br]you're going to have a flow of 0:15:40.170,0:15:41.480 water inside. 0:15:41.480,0:15:44.310 So in this situation, with a[br]semi-permeable membrane, 0:15:44.310,0:15:45.700 you're going to have water. 0:15:45.700,0:15:49.280 You're going to have a net[br]inward flow of water. 0:15:49.280,0:15:51.430 And so this is kind[br]of interesting. 0:15:51.430,0:15:56.900 We have the solvent flowing from[br]a hypotonic situation to 0:15:56.900,0:15:59.600 a hypertonic solution,[br]but it's only 0:15:59.600,0:16:01.210 hypotonic in the solute. 0:16:07.650,0:16:11.620 But water-- if you flip it the[br]other way-- if you've used 0:16:11.620,0:16:15.290 sugar as the solvent, then you[br]could say, we're going from a 0:16:15.290,0:16:19.470 high concentration of water to[br]a low concentration of water. 0:16:19.470,0:16:20.370 I don't want to confuse[br]you too much. 0:16:20.370,0:16:23.090 This is what tends to confuse[br]people, but just think about 0:16:23.090,0:16:24.040 what's going to happen. 0:16:24.040,0:16:27.260 No matter in what situation,[br]the solution is going to do 0:16:27.260,0:16:30.000 what it can to try to[br]equilibriate the 0:16:30.000,0:16:30.680 concentration. 0:16:30.680,0:16:32.080 To make the concentrations[br]on both 0:16:32.080,0:16:33.710 sides as close as possible. 0:16:33.710,0:16:35.150 And it's not just some magic. 0:16:35.150,0:16:36.160 It's not like the[br]solution knows. 0:16:36.160,0:16:38.300 It's all based on probabilities[br]and these things 0:16:38.300,0:16:41.050 bumping around, but in this[br]situation, water is more 0:16:41.050,0:16:43.790 likely to flow into[br]the container. 0:16:43.790,0:16:46.700 So it's actually going to go[br]from the hypotonic side when 0:16:46.700,0:16:50.460 we talk about low concentration[br]of solute to the 0:16:50.460,0:16:53.690 side that has high[br]concentrations of solute, of 0:16:53.690,0:16:57.320 sugar-- and actually, if this[br]thing is stretchable, more 0:16:57.320,0:17:01.670 water will keep flowing[br]in and this membrane 0:17:01.670,0:17:04.420 will stretch out. 0:17:04.420,0:17:08.420 I won't go to too much detail[br]here, but this idea of water-- 0:17:08.420,0:17:12.470 of the solvent-- if in this[br]case, water is the solvent-- 0:17:12.470,0:17:15.150 of water as a solvent[br]diffusing through a 0:17:15.150,0:17:18.500 semi-permeable membrane,[br]this is called osmosis. 0:17:22.569,0:17:25.170 You've probably heard learning[br]by osmosis-- if you put a book 0:17:25.170,0:17:27.200 against your head, maybe it'll[br]just seep into your brain. 0:17:27.200,0:17:28.000 Same idea. 0:17:28.000,0:17:29.500 That's where the word[br]comes from. 0:17:29.500,0:17:33.570 This idea of water seeping[br]through membranes to try to 0:17:33.570,0:17:35.600 make concentrations[br]more equal. 0:17:35.600,0:17:38.370 So if you say, well, I have high[br]concentration here, low 0:17:38.370,0:17:39.490 concentration here. 0:17:39.490,0:17:43.020 If there was no membrane here,[br]these big molecules would 0:17:43.020,0:17:48.080 exit, but because there's this[br]semi-permeable membrane here, 0:17:48.080,0:17:48.680 they can't. 0:17:48.680,0:17:52.400 So the system just[br]probabilistically-- no magic 0:17:52.400,0:17:56.090 here-- more water will enter[br]to try to equilibriate 0:17:56.090,0:17:57.160 concentration. 0:17:57.160,0:18:01.970 Eventually-- if maybe there's a[br]few molecules out here-- not 0:18:01.970,0:18:06.440 as high concentration here--[br]eventually if everything was 0:18:06.440,0:18:08.970 allowed to happen fully, you'll[br]get to the point where 0:18:08.970,0:18:11.120 you have just as many--[br]you have just as high 0:18:11.120,0:18:13.650 concentration on this side as[br]you have on the right-hand 0:18:13.650,0:18:16.500 side because this right-hand[br]side is going to fill with 0:18:16.500,0:18:19.380 water and also probably become[br]a larger volume. 0:18:19.380,0:18:21.520 And then, once again, the[br]probabilities of a water 0:18:21.520,0:18:23.600 molecule going to the right and[br]to the left will be the 0:18:23.600,0:18:25.920 same and you'll get to some[br]type of equilibrium. 0:18:25.920,0:18:29.910 But I want to make it very[br]clear-- diffusion is the idea 0:18:29.910,0:18:33.130 of any particle going from[br]higher concentration and 0:18:33.130,0:18:35.740 spreading into a region that has[br]a lower concentration and 0:18:35.740,0:18:36.950 just spreading out. 0:18:36.950,0:18:41.240 Osmosis is the diffusion[br]of water. 0:18:41.240,0:18:44.210 And usually you're talking about[br]the diffusion of water 0:18:44.210,0:18:47.010 as a solvent and usually it's[br]in the context of a 0:18:47.010,0:18:51.260 semi-permeable membrane, where[br]the actual solute cannot 0:18:51.260,0:18:53.530 travel through the membrane. 0:18:53.530,0:18:55.800 Anyway, hopefully you've[br]found that useful and 0:18:55.800,0:18:57.880 not completely confusing.