WEBVTT 00:00:01.280 --> 00:00:05.136 Computer algorithms today are performing incredible tasks 00:00:05.160 --> 00:00:09.896 with high accuracies, at a massive scale, using human-like intelligence. 00:00:09.920 --> 00:00:13.856 And this intelligence of computers is often referred to as AI 00:00:13.880 --> 00:00:15.736 or artificial intelligence. 00:00:15.760 --> 00:00:19.960 AI is poised to make an incredible impact on our lives in the future. 00:00:20.880 --> 00:00:24.816 Today, however, we still face massive challenges 00:00:24.840 --> 00:00:28.336 in detecting and diagnosing several life-threatening illnesses, 00:00:28.360 --> 00:00:30.720 such as infectious diseases and cancer. 00:00:32.000 --> 00:00:34.296 Thousands of patients every year 00:00:34.320 --> 00:00:37.120 lose their lives due to liver and oral cancer. NOTE Paragraph 00:00:37.880 --> 00:00:40.576 Our best way to help these patients 00:00:40.600 --> 00:00:44.920 is to perform early detection and diagnoses of these diseases. 00:00:45.880 --> 00:00:50.040 So how do we detect these diseases today, and can artificial intelligence help? 00:00:51.920 --> 00:00:55.576 In patients who, unfortunately, are suspected of these diseases, 00:00:55.600 --> 00:00:58.256 an expert physician first orders 00:00:58.280 --> 00:01:00.896 very expensive medical imaging technologies 00:01:00.920 --> 00:01:05.016 such as fluorescent imaging, CTs, MRIs, to be performed. 00:01:05.040 --> 00:01:07.336 Once those images are collected, 00:01:07.360 --> 00:01:11.880 another expert physician then diagnoses those images and talks to the patient. 00:01:12.520 --> 00:01:15.976 As you can see, this is a very resource-intensive process, 00:01:16.000 --> 00:01:20.416 requiring both expert physicians, expensive medical imaging technologies, 00:01:20.440 --> 00:01:23.536 and is not considered practical for the developing world. 00:01:23.560 --> 00:01:26.920 And in fact, in many industrialized nations, as well. NOTE Paragraph 00:01:27.760 --> 00:01:30.640 So, can we solve this problem using artificial intelligence? 00:01:31.840 --> 00:01:35.896 Today, if I were to use traditional artificial intelligence architectures 00:01:35.920 --> 00:01:37.136 to solve this problem, 00:01:37.160 --> 00:01:38.616 I would require 10,000 -- 00:01:38.640 --> 00:01:42.656 I repeat, on an order of 10,000 of these very expensive medical images 00:01:42.680 --> 00:01:44.056 first to be generated. 00:01:44.080 --> 00:01:46.976 After that, I would then go to an expert physician, 00:01:47.000 --> 00:01:49.496 who would then analyze those images for me. 00:01:49.520 --> 00:01:51.616 And using those two pieces of information, 00:01:51.640 --> 00:01:55.296 I can train a standard deep neural network or a deep learning network 00:01:55.320 --> 00:01:57.456 to provide patient's diagnosis. 00:01:57.480 --> 00:01:59.216 Similar to the first approach, 00:01:59.240 --> 00:02:01.383 traditional artificial intelligence approaches 00:02:01.407 --> 00:02:02.856 suffer from the same problem. 00:02:02.880 --> 00:02:07.440 Large amounts of data, expert physicians and expert medical imaging technologies. NOTE Paragraph 00:02:08.320 --> 00:02:12.616 So, can we invent more scalable, effective 00:02:12.640 --> 00:02:15.936 and more valuable artificial intelligence architectures 00:02:15.960 --> 00:02:19.016 to solve these very important problems facing us today? 00:02:19.040 --> 00:02:22.336 And this is exactly what my group at MIT Media Lab does. 00:02:22.360 --> 00:02:26.216 We have invented a variety of unorthodox AI architectures 00:02:26.240 --> 00:02:29.416 to solve some of the most important challenges facing us today 00:02:29.440 --> 00:02:31.640 in medical imaging and clinical trials. NOTE Paragraph 00:02:32.480 --> 00:02:35.536 In the example I shared with you today, we had two goals. 00:02:35.560 --> 00:02:38.536 Our first goal was to reduce the number of images 00:02:38.560 --> 00:02:41.816 required to train artificial intelligence algorithms. 00:02:41.840 --> 00:02:43.936 Our second goal -- we were more ambitious, 00:02:43.960 --> 00:02:47.696 we wanted to reduce the use of expensive medical imaging technologies 00:02:47.720 --> 00:02:48.936 to screen patients. 00:02:48.960 --> 00:02:50.160 So how did we do it? NOTE Paragraph 00:02:50.920 --> 00:02:52.136 For our first goal, 00:02:52.160 --> 00:02:54.216 instead of starting with tens and thousands 00:02:54.240 --> 00:02:57.256 of these very expensive medical images, like traditional AI, 00:02:57.280 --> 00:02:59.336 we started with a single medical image. 00:02:59.360 --> 00:03:03.136 From this image, my team and I figured out a very clever way 00:03:03.160 --> 00:03:05.896 to extract billions of information packets. 00:03:05.920 --> 00:03:09.616 These information packets included colors, pixels, geometry 00:03:09.640 --> 00:03:12.176 and rendering of the disease on the medical image. 00:03:12.200 --> 00:03:16.536 In a sense, we converted one image into billions of training data points, 00:03:16.560 --> 00:03:20.096 massively reducing the amount of data needed for training. NOTE Paragraph 00:03:20.120 --> 00:03:21.336 For our second goal, 00:03:21.360 --> 00:03:25.216 to reduce the use of expensive medical imaging technologies to screen patients, 00:03:25.240 --> 00:03:28.096 we started with a standard, white light photograph, 00:03:28.120 --> 00:03:32.456 acquired either from a DSLR camera or a mobile phone, for the patient. 00:03:32.480 --> 00:03:34.936 Then remember those billions of information packets? 00:03:34.960 --> 00:03:38.496 We overlaid those from the medical image onto this image, 00:03:38.520 --> 00:03:41.040 creating something that we call a composite image. 00:03:41.480 --> 00:03:44.776 Much to our surprise, we only required 50 -- 00:03:44.800 --> 00:03:46.136 I repeat, only 50 -- 00:03:46.160 --> 00:03:50.000 of these composite images to train our algorithms to high efficiencies. NOTE Paragraph 00:03:50.680 --> 00:03:52.016 To summarize our approach, 00:03:52.040 --> 00:03:55.216 instead of using 10,000 very expensive medical images, 00:03:55.240 --> 00:03:58.256 we can now train the AI algorithms in an unorthodox way, 00:03:58.280 --> 00:04:02.536 using only 50 of these high-resolution, but standard photographs, 00:04:02.560 --> 00:04:05.056 acquired from DSLR cameras and mobile phones, 00:04:05.080 --> 00:04:06.616 and provide diagnosis. 00:04:06.640 --> 00:04:07.856 More importantly, 00:04:07.880 --> 00:04:11.016 our algorithms can accept, in the future and even right now, 00:04:11.040 --> 00:04:13.856 some very simple, white light photographs from the patient, 00:04:13.880 --> 00:04:16.320 instead of expensive medical imaging technologies. NOTE Paragraph 00:04:17.120 --> 00:04:20.216 I believe that we are poised to enter an era 00:04:20.240 --> 00:04:22.176 where artificial intelligence 00:04:22.200 --> 00:04:24.736 is going to make an incredible impact on our future. 00:04:24.760 --> 00:04:27.216 And I think that thinking about traditional AI, 00:04:27.240 --> 00:04:30.016 which is data-rich but application-poor, 00:04:30.040 --> 00:04:31.576 we should also continue thinking 00:04:31.600 --> 00:04:34.616 about unorthodox artificial intelligence architectures, 00:04:34.640 --> 00:04:36.576 which can accept small amounts of data 00:04:36.600 --> 00:04:39.536 and solve some of the most important problems facing us today, 00:04:39.560 --> 00:04:40.816 especially in health care. NOTE Paragraph 00:04:40.840 --> 00:04:42.056 Thank you very much. NOTE Paragraph 00:04:42.080 --> 00:04:45.920 (Applause)