1 00:00:01,280 --> 00:00:05,136 Computer algorithms today are performing incredible tasks 2 00:00:05,160 --> 00:00:09,896 with high accuracies, at a massive scale, using human-like intelligence. 3 00:00:09,920 --> 00:00:13,856 And this intelligence of computers is often referred to as AI 4 00:00:13,880 --> 00:00:15,736 or artificial intelligence. 5 00:00:15,760 --> 00:00:19,960 AI is poised to make an incredible impact on our lives in the future. 6 00:00:20,880 --> 00:00:24,816 Today, however, we still face massive challenges 7 00:00:24,840 --> 00:00:28,336 in detecting and diagnosing several life-threatening illnesses, 8 00:00:28,360 --> 00:00:30,720 such as infectious diseases and cancer. 9 00:00:32,000 --> 00:00:34,296 Thousands of patients every year 10 00:00:34,320 --> 00:00:37,120 lose their lives due to liver and oral cancer. 11 00:00:37,880 --> 00:00:40,576 Our best way to help these patients 12 00:00:40,600 --> 00:00:44,920 is to perform early detection and diagnoses of these diseases. 13 00:00:45,880 --> 00:00:50,040 So how do we detect these diseases today, and can artificial intelligence help? 14 00:00:51,920 --> 00:00:55,576 In patients who, unfortunately, are suspected of these diseases, 15 00:00:55,600 --> 00:00:58,256 an expert physician first orders 16 00:00:58,280 --> 00:01:00,896 very expensive medical imaging technologies 17 00:01:00,920 --> 00:01:05,016 such as fluorescent imaging, CTs, MRIs, to be performed. 18 00:01:05,040 --> 00:01:07,336 Once those images are collected, 19 00:01:07,360 --> 00:01:11,880 another expert physician then diagnoses those images and talks to the patient. 20 00:01:12,520 --> 00:01:15,976 As you can see, this is a very resource-intensive process, 21 00:01:16,000 --> 00:01:20,416 requiring both expert physicians, expensive medical imaging technologies, 22 00:01:20,440 --> 00:01:23,536 and is not considered practical for the developing world. 23 00:01:23,560 --> 00:01:26,920 And in fact, in many industrialized nations, as well. 24 00:01:27,760 --> 00:01:30,640 So, can we solve this problem using artificial intelligence? 25 00:01:31,840 --> 00:01:35,896 Today, if I were to use traditional artificial intelligence architectures 26 00:01:35,920 --> 00:01:37,136 to solve this problem, 27 00:01:37,160 --> 00:01:38,616 I would require 10,000 -- 28 00:01:38,640 --> 00:01:42,656 I repeat, on an order of 10,000 of these very expensive medical images 29 00:01:42,680 --> 00:01:44,056 first to be generated. 30 00:01:44,080 --> 00:01:46,976 After that, I would then go to an expert physician, 31 00:01:47,000 --> 00:01:49,496 who would then analyze those images for me. 32 00:01:49,520 --> 00:01:51,616 And using those two pieces of information, 33 00:01:51,640 --> 00:01:55,296 I can train a standard deep neural network or a deep learning network 34 00:01:55,320 --> 00:01:57,456 to provide patient's diagnosis. 35 00:01:57,480 --> 00:01:59,216 Similar to the first approach, 36 00:01:59,240 --> 00:02:01,383 traditional artificial intelligence approaches 37 00:02:01,407 --> 00:02:02,856 suffer from the same problem. 38 00:02:02,880 --> 00:02:07,440 Large amounts of data, expert physicians and expert medical imaging technologies. 39 00:02:08,320 --> 00:02:12,616 So, can we invent more scalable, effective 40 00:02:12,640 --> 00:02:15,936 and more valuable artificial intelligence architectures 41 00:02:15,960 --> 00:02:19,016 to solve these very important problems facing us today? 42 00:02:19,040 --> 00:02:22,336 And this is exactly what my group at MIT Media Lab does. 43 00:02:22,360 --> 00:02:26,216 We have invented a variety of unorthodox AI architectures 44 00:02:26,240 --> 00:02:29,416 to solve some of the most important challenges facing us today 45 00:02:29,440 --> 00:02:31,640 in medical imaging and clinical trials. 46 00:02:32,480 --> 00:02:35,536 In the example I shared with you today, we had two goals. 47 00:02:35,560 --> 00:02:38,536 Our first goal was to reduce the number of images 48 00:02:38,560 --> 00:02:41,816 required to train artificial intelligence algorithms. 49 00:02:41,840 --> 00:02:43,936 Our second goal -- we were more ambitious, 50 00:02:43,960 --> 00:02:47,696 we wanted to reduce the use of expensive medical imaging technologies 51 00:02:47,720 --> 00:02:48,936 to screen patients. 52 00:02:48,960 --> 00:02:50,160 So how did we do it? 53 00:02:50,920 --> 00:02:52,136 For our first goal, 54 00:02:52,160 --> 00:02:54,216 instead of starting with tens and thousands 55 00:02:54,240 --> 00:02:57,256 of these very expensive medical images, like traditional AI, 56 00:02:57,280 --> 00:02:59,336 we started with a single medical image. 57 00:02:59,360 --> 00:03:03,136 From this image, my team and I figured out a very clever way 58 00:03:03,160 --> 00:03:05,896 to extract billions of information packets. 59 00:03:05,920 --> 00:03:09,616 These information packets included colors, pixels, geometry 60 00:03:09,640 --> 00:03:12,176 and rendering of the disease on the medical image. 61 00:03:12,200 --> 00:03:16,536 In a sense, we converted one image into billions of training data points, 62 00:03:16,560 --> 00:03:20,096 massively reducing the amount of data needed for training. 63 00:03:20,120 --> 00:03:21,336 For our second goal, 64 00:03:21,360 --> 00:03:25,216 to reduce the use of expensive medical imaging technologies to screen patients, 65 00:03:25,240 --> 00:03:28,096 we started with a standard, white light photograph, 66 00:03:28,120 --> 00:03:32,456 acquired either from a DSLR camera or a mobile phone, for the patient. 67 00:03:32,480 --> 00:03:34,936 Then remember those billions of information packets? 68 00:03:34,960 --> 00:03:38,496 We overlaid those from the medical image onto this image, 69 00:03:38,520 --> 00:03:41,040 creating something that we call a composite image. 70 00:03:41,480 --> 00:03:44,776 Much to our surprise, we only required 50 -- 71 00:03:44,800 --> 00:03:46,136 I repeat, only 50 -- 72 00:03:46,160 --> 00:03:50,000 of these composite images to train our algorithms to high efficiencies. 73 00:03:50,680 --> 00:03:52,016 To summarize our approach, 74 00:03:52,040 --> 00:03:55,216 instead of using 10,000 very expensive medical images, 75 00:03:55,240 --> 00:03:58,256 we can now train the AI algorithms in an unorthodox way, 76 00:03:58,280 --> 00:04:02,536 using only 50 of these high-resolution, but standard photographs, 77 00:04:02,560 --> 00:04:05,056 acquired from DSLR cameras and mobile phones, 78 00:04:05,080 --> 00:04:06,616 and provide diagnosis. 79 00:04:06,640 --> 00:04:07,856 More importantly, 80 00:04:07,880 --> 00:04:11,016 our algorithms can accept, in the future and even right now, 81 00:04:11,040 --> 00:04:13,856 some very simple, white light photographs from the patient, 82 00:04:13,880 --> 00:04:16,320 instead of expensive medical imaging technologies. 83 00:04:17,120 --> 00:04:20,216 I believe that we are poised to enter an era 84 00:04:20,240 --> 00:04:22,176 where artificial intelligence 85 00:04:22,200 --> 00:04:24,736 is going to make an incredible impact on our future. 86 00:04:24,760 --> 00:04:27,216 And I think that thinking about traditional AI, 87 00:04:27,240 --> 00:04:30,016 which is data-rich but application-poor, 88 00:04:30,040 --> 00:04:31,576 we should also continue thinking 89 00:04:31,600 --> 00:04:34,616 about unorthodox artificial intelligence architectures, 90 00:04:34,640 --> 00:04:36,576 which can accept small amounts of data 91 00:04:36,600 --> 00:04:39,536 and solve some of the most important problems facing us today, 92 00:04:39,560 --> 00:04:40,816 especially in health care. 93 00:04:40,840 --> 00:04:42,056 Thank you very much. 94 00:04:42,080 --> 00:04:45,920 (Applause)